J C Wu

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint The effect of sleep deprivation on cerebral glucose metabolic rate in normal humans assessed with positron emission tomography
    J C Wu
    University of California, Irvine
    Sleep 14:155-62. 1991
  2. ncbi request reprint A PET study of the pathophysiology of negative symptoms in schizophrenia. Positron emission tomography
    Steven G Potkin
    Department of Psychiatry and Human Behavior, University of California, Irvine 92697 3960, USA
    Am J Psychiatry 159:227-37. 2002
  3. ncbi request reprint Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation
    Feng Cao
    The Department of Radiology and Bio X Program, Stanford University School of Medicine, Stanford, California 94305 5344, USA
    Cloning Stem Cells 9:107-17. 2007
  4. ncbi request reprint Sleep deprivation PET correlations of Hamilton symptom improvement ratings with changes in relative glucose metabolism in patients with depression
    Joseph C Wu
    UC Irvine Department of Psychiatry and Human Behavior, Irvine, California 92697 3960, United States
    J Affect Disord 107:181-6. 2008
  5. doi request reprint Rapid and sustained antidepressant response with sleep deprivation and chronotherapy in bipolar disorder
    Joseph C Wu
    Department of Psychiatry and Human Behavior, University of California at Irvine School of Medicine, Room 109, Irvine Hall, Irvine, CA 92697 3960, USA
    Biol Psychiatry 66:298-301. 2009
  6. ncbi request reprint Frontal lobe metabolic decreases with sleep deprivation not totally reversed by recovery sleep
    Joseph C Wu
    UC Irvine Department of Psychiatry and Human Behavior, Irvine, CA, USA
    Neuropsychopharmacology 31:2783-92. 2006
  7. ncbi request reprint Prediction of antidepressant effects of sleep deprivation by metabolic rates in the ventral anterior cingulate and medial prefrontal cortex
    J Wu
    Department of Psychiatry and Human Behavior, College of Medicine, University of California, Irvine 92717, USA
    Am J Psychiatry 156:1149-58. 1999
  8. ncbi request reprint Clinical neurochemical implications of sleep deprivation's effects on the anterior cingulate of depressed responders
    J C Wu
    Department of Psychiatry, University of California, Irvine 92717, USA
    Neuropsychopharmacology 25:S74-8. 2001
  9. ncbi request reprint Effects of amoxapine and imipramine on evoked potentials in the Continuous Performance Test in patients with affective disorder
    M S Buchsbaum
    Department of Psychiatry, University of California, Irvine
    Neuropsychobiology 20:15-22. 1988
  10. ncbi request reprint Brain metabolic and clinical effects of rivastigmine in Alzheimer's disease
    S G Potkin
    Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92627 3960, USA
    Int J Neuropsychopharmacol 4:223-30. 2001

Collaborators

Detail Information

Publications35

  1. ncbi request reprint The effect of sleep deprivation on cerebral glucose metabolic rate in normal humans assessed with positron emission tomography
    J C Wu
    University of California, Irvine
    Sleep 14:155-62. 1991
    ....
  2. ncbi request reprint A PET study of the pathophysiology of negative symptoms in schizophrenia. Positron emission tomography
    Steven G Potkin
    Department of Psychiatry and Human Behavior, University of California, Irvine 92697 3960, USA
    Am J Psychiatry 159:227-37. 2002
    ....
  3. ncbi request reprint Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation
    Feng Cao
    The Department of Radiology and Bio X Program, Stanford University School of Medicine, Stanford, California 94305 5344, USA
    Cloning Stem Cells 9:107-17. 2007
    ....
  4. ncbi request reprint Sleep deprivation PET correlations of Hamilton symptom improvement ratings with changes in relative glucose metabolism in patients with depression
    Joseph C Wu
    UC Irvine Department of Psychiatry and Human Behavior, Irvine, California 92697 3960, United States
    J Affect Disord 107:181-6. 2008
    ..In addition, we also studied the effect of concomitant antidepressant medication in conjunction with sleep depression...
  5. doi request reprint Rapid and sustained antidepressant response with sleep deprivation and chronotherapy in bipolar disorder
    Joseph C Wu
    Department of Psychiatry and Human Behavior, University of California at Irvine School of Medicine, Room 109, Irvine Hall, Irvine, CA 92697 3960, USA
    Biol Psychiatry 66:298-301. 2009
    ..This study evaluates the combined efficacy of three established circadian-related treatments (SD, bright light [BL]), sleep phase advance [SPA]) as adjunctive treatment to lithium and antidepressants...
  6. ncbi request reprint Frontal lobe metabolic decreases with sleep deprivation not totally reversed by recovery sleep
    Joseph C Wu
    UC Irvine Department of Psychiatry and Human Behavior, Irvine, CA, USA
    Neuropsychopharmacology 31:2783-92. 2006
    ..Recovery sleep was found to have only a partial restorative effect on frontal lobe function with minimal reversal of subcortical deficits. Sleep may be especially important for maintenance of frontal lobe activity...
  7. ncbi request reprint Prediction of antidepressant effects of sleep deprivation by metabolic rates in the ventral anterior cingulate and medial prefrontal cortex
    J Wu
    Department of Psychiatry and Human Behavior, College of Medicine, University of California, Irvine 92717, USA
    Am J Psychiatry 156:1149-58. 1999
    ..The authors extend their earlier work in a larger group of patients and explore additional brain areas with statistical probability mapping...
  8. ncbi request reprint Clinical neurochemical implications of sleep deprivation's effects on the anterior cingulate of depressed responders
    J C Wu
    Department of Psychiatry, University of California, Irvine 92717, USA
    Neuropsychopharmacology 25:S74-8. 2001
    ..The neurochemical implications of these findings are explored. Possible dopaminergic and serotonergic mechanisms are discussed...
  9. ncbi request reprint Effects of amoxapine and imipramine on evoked potentials in the Continuous Performance Test in patients with affective disorder
    M S Buchsbaum
    Department of Psychiatry, University of California, Irvine
    Neuropsychobiology 20:15-22. 1988
    ..CPT performance was significantly better on amoxapine than placebo...
  10. ncbi request reprint Brain metabolic and clinical effects of rivastigmine in Alzheimer's disease
    S G Potkin
    Department of Psychiatry and Human Behavior, University of California, Irvine, CA 92627 3960, USA
    Int J Neuropsychopharmacol 4:223-30. 2001
    ..Rivastigmine prevented the expected deterioration in clinical status and dramatically increased brain metabolic activity in a majority of patients...
  11. doi request reprint The relationship of respiratory and cardiovascular hospital admissions to the southern California wildfires of 2003
    R J Delfino
    Epidemiology Department, School of Medicine, University of California Irvine, 100 Theory Drive, Irvine, CA 92617 7555, USA
    Occup Environ Med 66:189-97. 2009
    ..The relationship of cardiorespiratory hospital admissions (n = 40 856) to wildfire-related particulate matter (PM(2.5)) during catastrophic wildfires in southern California in October 2003 was evaluated...
  12. ncbi request reprint Sleep deprivation as a model experimental antidepressant treatment: findings from functional brain imaging
    J C Gillin
    Department of Psychiatry, UCSD and VA San Diego Healthcare System 116a, 3350 La Jolla Village Drive, San Diego, CA 92161, USA
    Depress Anxiety 14:37-49. 2001
    ..Finally, a SPECT study using a radioactively labeled D2 receptor antagonist suggests that the antidepressant benefits of sleep deprivation are correlated with endogenous release of dopamine...
  13. ncbi request reprint D1 receptor alleles predict PET metabolic correlates of clinical response to clozapine
    S G Potkin
    Department of Psychiatry and Human Behavior, University of Caliornia, Irvine 92697 3960, USA
    Mol Psychiatry 8:109-13. 2003
    ..05). In this preliminary study, brain metabolic and clinical response to clozapine are related to the D1 receptor genotype...
  14. pmc Neural correlates of STN DBS-induced cognitive variability in Parkinson disease
    M C Campbell
    Department of Psychiatry, Washington University School of Medicine, St Louis, MO 63110, United States
    Neuropsychologia 46:3162-9. 2008
    ..The purpose of this study was to determine the neural correlates of STN DBS-induced variability in cognitive performance...
  15. ncbi request reprint Positron emission tomography with deoxyglucose-F18 imaging of sleep
    M S Buchsbaum
    Neuroscience PET Laboratory, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    Neuropsychopharmacology 25:S50-6. 2001
    ..Compared with REM sleep, nonREM sleep was associated with significantly lower metabolic rates in the temporal and occipital regions, as well as the thalamus...
  16. ncbi request reprint Localized and lateralized cerebral glucose metabolism associated with eye movements during REM sleep and wakefulness: a positron emission tomography (PET) study
    C C Hong
    Department of Psychiatry, University of California, San Diego, La Jolla 92093-0603, USA
    Sleep 18:570-80. 1995
    ..Our data also suggest right hemispheric specialization in saccadic eye movement control and reciprocal inhibition in the contralateral homologous area during higher cortical functioning...
  17. ncbi request reprint Expression of the human integrin beta6 subunit in alveolar type II cells and bronchiolar epithelial cells reverses lung inflammation in beta6 knockout mice
    X Huang
    Lung Biology Center, and the Department of Medicine, University of California, San Francisco, USA
    Am J Respir Cell Mol Biol 19:636-42. 1998
    ....
  18. ncbi request reprint Brightening depression
    Anna Wirz-Justice
    Science 303:467-9. 2004
  19. pmc Positron emission tomography imaging of conditional gene activation in the heart
    Gwendolen Y Chang
    The Molecular Imaging Program at Stanford MIPS and Department of Radiology, Stanford University, Palo Alto, CA, USA
    J Mol Cell Cardiol 43:18-26. 2007
    ..With further development and validation, PET imaging will likely play an important role in the noninvasive, repetitive, and quantitative measurement of conditional gene activation in the future...
  20. pmc Reporter gene imaging following percutaneous delivery in swine moving toward clinical applications
    Martin Rodriguez-Porcel
    J Am Coll Cardiol 51:595-7. 2008
  21. pmc Imaging of VEGF receptor in a rat myocardial infarction model using PET
    Martin Rodriguez-Porcel
    Molecular Imaging Program at Stanford, Department of Radiology, Division of Nuclear Medicine, Stanford University, Stanford, CA 94305 5427, USA
    J Nucl Med 49:667-73. 2008
    ..We have developed a PET tracer (64Cu-DOTA-VEGF121 [DOTA is 1,4,7,10-tetraazadodecane-N,N',N'',N'''-tetraacetic acid]) to image VEGF receptor (VEGFR) expression after MI in the living subject...
  22. ncbi request reprint Can radionuclide imaging predict future response to stem cell therapy?
    Joseph C Wu
    J Nucl Cardiol 15:308-10. 2008
  23. doi request reprint Intracellular and extracellular targets of molecular imaging in the myocardium
    Hyung J Chun
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305 5344, USA
    Nat Clin Pract Cardiovasc Med 5:S33-41. 2008
    ..Further development of these imaging targets may lead to improved characterization of disease processes and guide provision of individualized therapies...
  24. doi request reprint Noninvasive radionuclide imaging of cardiac gene therapy: progress and potential
    Asimina Hiona
    Department of Radiology, Molecular Imaging Program at Stanford, Stanford University School of Medicine, Stanford, CA 94305 5344, USA
    Nat Clin Pract Cardiovasc Med 5:S87-95. 2008
    ..We discuss limitations of current methods for analyzing gene transfer and describe how reporter gene imaging works...
  25. ncbi request reprint Clinical hurdles for the transplantation of cardiomyocytes derived from human embryonic stem cells: role of molecular imaging
    Rutger Jan Swijnenburg
    Molecular Imaging Program at Stanford, Department of Radiology, Stanford University, Stanford, California, USA
    Curr Opin Biotechnol 18:38-45. 2007
    ..Therefore, molecular imaging is expected to play an increasing role in characterizing the biology and physiology of hESC-derived cardiac cells in living subjects...
  26. ncbi request reprint Positron emission tomography imaging of cardiac reporter gene expression in living rats
    Joseph C Wu
    Crump Institute for Molecular Imaging, UCLA School of Medicine, Los Angeles, Calif 90095 1770, USA
    Circulation 106:180-3. 2002
    ..Imaging reporter gene expression is useful for noninvasive monitoring of gene therapy. In this study, we imaged cardiac reporter gene expression in living rats using micro positron emission tomography (microPET)...
  27. ncbi request reprint Positron-emission tomography reporter gene expression imaging in rat myocardium
    Masayuki Inubushi
    Department of Molecular and Medical Pharmacology, The Crump Institute for Molecular Imaging, University of California, Los Angeles 90095 1735, USA
    Circulation 107:326-32. 2003
    ....
  28. ncbi request reprint Molecular imaging of cardiac cell transplantation in living animals using optical bioluminescence and positron emission tomography
    Joseph C Wu
    Department of Molecular and Medical Pharmacology and Crump Institute for Molecular Imaging, UCLA School of Medicine, Los Angeles, Calif, USA
    Circulation 108:1302-5. 2003
    ..The current method of analyzing myocardial cell transplantation relies on postmortem histology. We sought to demonstrate the feasibility of monitoring transplanted cell survival in living animals using molecular imaging techniques...
  29. ncbi request reprint Molecular imaging of the kinetics of vascular endothelial growth factor gene expression in ischemic myocardium
    Joseph C Wu
    Department of Molecular and Medical Pharmacology, the Crump Institute of Molecular Imaging, UCLA School of Medicine, Los Angeles, Calif, USA
    Circulation 110:685-91. 2004
    ..In this study, we used micro-positron emission tomography (microPET) to monitor the transgene expression, function, and effects in a whole-body system...
  30. ncbi request reprint Human gene therapy and imaging: cardiology
    Joseph C Wu
    Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Edwards Building, Room R354, Stanford, CA 94305 5344, USA
    Eur J Nucl Med Mol Imaging 32:S346-57. 2005
    ....
  31. ncbi request reprint Imaging chemically modified adenovirus for targeting tumors expressing integrin alphavbeta3 in living mice with mutant herpes simplex virus type 1 thymidine kinase PET reporter gene
    Zhengming Xiong
    Molecular Imaging Program at Stanford, MIPS, Department of Radiology, Stanford University School of Medicine, California 94305 5484, USA
    J Nucl Med 47:130-9. 2006
    ....
  32. ncbi request reprint In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery
    Feng Cao
    Department of Radiology, Bio X Program, Stanford University School of Medicine, Stanford, CA 94305 5344, USA
    Circulation 113:1005-14. 2006
    ..Recent studies have shown that stem cell therapy can promote tissue regeneration; however, monitoring stem cells in vivo remains problematic owing to limitations of conventional histological assays and imaging modalities...
  33. ncbi request reprint 18F-labeled bombesin analogs for targeting GRP receptor-expressing prostate cancer
    Xianzhong Zhang
    Molecular Imaging Program at Stanford MIPS, Department of Radiology and Bio X Program, Stanford University School of Medicine, Stanford, California 94305 5484, USA
    J Nucl Med 47:492-501. 2006
    ..The gastrin-releasing peptide receptor (GRPR) is found to be overexpressed in a variety of human tumors. The aim of this study was to develop 18F-labeled bombesin analogs for PET of GRPR expression in prostate cancer xenograft models...
  34. ncbi request reprint Molecular imaging of cardiac stem cell transplantation
    Ahmad Y Sheikh
    Department of Medicine, Division of Cardiology and Radiology, Molecular Imaging Program at Stanford, Stanford University School of Medicine, Edwards Building, Room R 354, Stanford, CA 94305 5324, USA
    Curr Cardiol Rep 8:147-54. 2006
    ..This article provides a focused overview of clinical stem cell therapy for the heart, followed by a discussion of how novel molecular imaging techniques are presently being applied to monitor cell therapy...
  35. ncbi request reprint Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation
    Joseph C Wu
    Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, USA
    Physiol Genomics 25:29-38. 2006
    ..Taken together, this is the first study to analyze in detail the effects of reporter genes on molecular imaging of ES cells...