Research Topics
| Baolin WuSummaryAffiliation: University of Minnesota Country: USA Publications
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Detail Information
Publications
Cancer outlier differential gene expression detectionBaolin Wu
Division of Biostatistics, School of Public Health, University of Minnesota, A460 Mayo Building, MMC 303, Minneapolis, MN 55455, USA
Biostatistics 8:566-75. 2007..The proposed method often has more detection power and smaller false discovery rates. Supplementary information can be found at http://www.biostat.umn.edu/~baolin/research/ort.html...
Evolution of clipping for thoracoscopic sympathectomy in symptomatic hyperhidrosisBryan A Whitson
Section of Thoracic and Foregut Surgery, University of Minnesota, Department of Surgery and Center for Minimally Invasive Surgery, Minneapolis, MN 55455, USA
Surg Laparosc Endosc Percutan Tech 17:287-90. 2007..Severe hyperhidrosis is treated by thoracic sympathetic chain interrupting through chain transection or clipping. Our study compared the efficacy of these 2 methods...
Video-assisted thoracoscopic surgery is more favorable than thoracotomy for resection of clinical stage I non-small cell lung cancerBryan A Whitson
Department of Surgery, Section of Thoracic and Foregut Surgery, University of Minnesota Medical Center, Minneapolis, Minnesota 55455, USA
Ann Thorac Surg 83:1965-70. 2007..We compared the operative characteristics and postoperative course for patients with clinical stage I NSCLC who underwent lobectomy by VATS or thoracotomy...
Levitronix ventricular assist devices as a bridge to recovery after profound biventricular heart failure associated with pulmonary aspergillosisBryan A Whitson
Department of Surgery, Division of Cardiovascular and Thoracic Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA
J Heart Lung Transplant 26:345-9. 2007..Ventricular assist devices should be strongly considered, as bridges to recovery, to support patients with acute myocardial dysfunction associated with sepsis while the underlying infection is treated...
Spontaneous posterior rectus sheath hernia: a new clinical entity?B A Whitson
Department of Surgery, University of Minnesota, MMC 195, 420 Delaware St SE, Minneapolis, MN 55455, USA
Hernia 11:445-7. 2007..This is accompanied with a review of the literature and the suggestion that spontaneous posterior rectus sheath herniation is possibly a separate clinical entity...
Minimally invasive cancer surgery improves patient survival rates through less perioperative immunosuppressionB A Whitson
Section of Thoracic and Foregut Surgery, University of Minnesota, Department of Surgery, MMC 207, 420 Delaware St SE, Minneapolis, MN 55455, USA
Med Hypotheses 68:1328-32. 2007..A deeper understanding of the integral components of the immune response to surgery would open the door for immunomodulation strategies and be of great clinical utility in guiding neoadjuvant, surgical, or adjuvant therapeutic decisions...
Minimally invasive versus open Roux-en-Y gastric bypass: effect on immune effector cellsBryan A Whitson
Department of Surgery, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
Surg Obes Relat Dis 5:181-93. 2009..We hypothesized that the open approach to Roux-en-Y gastric bypass (RYGB) has a more deleterious, negative, quantifiable effect on the peripheral blood mononuclear cells than does the MIS approach...
Thoracoscopic versus thoracotomy approaches to lobectomy: differential impairment of cellular immunityBryan A Whitson
Department of Surgery, University of Minnesota, Minneapolis, Minnesota, USA
Ann Thorac Surg 86:1735-44. 2008..Specifically, we assessed the cytotoxic capacity of peripheral blood mononuclear cells (PBMCs) of patients undergoing lobectomy for non-small-cell lung cancer by either VATS or thoracotomy...
A role for MEIS1 in MLL-fusion gene leukemiaAshish R Kumar
Masonic Cancer Center, Minneapolis, MN 55455, USA
Blood 113:1756-8. 2009..Targeting MEIS1 may have therapeutic potential for treating leukemias expressing this transcription factor...
Multi-group cancer outlier differential gene expression detectionFang Liu
Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA
Comput Biol Chem 31:65-71. 2007..Supplementary information can be found at http://www.biostat.umn.edu/~baolin/research/orf.html...
Parametric and nonparametric FDR estimation revisitedBaolin Wu
Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55455, USA
Biometrics 62:735-44. 2006..Based on our results, we advocate using the parametric approach, or directly modeling the test statistics using the empirical Bayes method...
Quantitative proteomics reveals myosin and actin as promising saliva biomarkers for distinguishing pre-malignant and malignant oral lesionsEbbing P de Jong
Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA
PLoS ONE 5:e11148. 2010..A test for proteins, ones found in non-invasively-collected whole saliva and whose abundances distinguish these lesion types, would meet this critical need...
Differential gene expression detection and sample classification using penalized linear regression modelsBaolin Wu
Division of Biostatistics, School of Public Health, University of Minnesota, A460 Mayo Building, MMC 303, Minneapolis, MN 55455, USA
Bioinformatics 22:472-6. 2006..using the (1) penalized regression models. And we show that the penalized linear regression models provide a rigorous and unified statistical framework for sample classification and differential gene expression detection...
Sparse regularized discriminant analysis with application to microarraysRan Li
Division of Biostatistics, School of Public Health University of Minnesota, Minneapolis, MN 55455, USA
Comput Biol Chem 39:14-9. 2012..We will illustrate its competitive performance through simulation studies and applications to public microarray data...
Robust and efficient identification of biomarkers by classifying features on graphsTaeHyun Hwang
Department of Computer Science and Engineering, University of Minnesota, Twin Cities, Bioinformatics Core, Mayo Clinic College of Medicine, Rochester, MN, USA
Bioinformatics 24:2023-9. 2008..In addition, although designed for classifying features, our algorithm can also simultaneously classify test samples for disease prognosis/diagnosis...
Functional group-based linkage analysis of gene expression trait lociNa Li
Division of Biostatistics, University of Minnesota, A460 Mayo Building MMC 303, 420 Delaware Street Southeast, Minneapolis, Minnesota 55126, USA
BMC Proc 1:S117. 2007..Future research is needed to develop rigorous methods in mapping of genes affecting the expression of a group of transcripts...
Cerebral malaria in children is associated with long-term cognitive impairmentChandy C John
Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota, USA
Pediatrics 122:e92-9. 2008..This study was conducted to determine the long-term effects of cerebral malaria on the cognitive function of these children...
PSMIX: an R package for population structure inference via maximum likelihood methodBaolin Wu
Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, USA
BMC Bioinformatics 7:317. 2006..However, these Bayesian methods demand intensive computation resources and may run into convergence problem in Markov Chain Monte Carlo based posterior samplings...
Proteome of human calcium kidney stonesBenjamin K Canales
Department of Urology, University of Minnesota, Minneapolis, Minnesota, USA
Urology 76:1017.e13-20. 2010..If this is true, we theorize that differences will be seen within the organic portion (matrix) of CaOx stones compared with CaP stones using a mass spectroscopy (MS) approach...
LTQ-iQuant: A freely available software pipeline for automated and accurate protein quantification of isobaric tagged peptide data from LTQ instrumentsGetiria Onsongo
Department of Computer Science and Engineering, University of Minnesota, Minneapolis, MN, USA
Proteomics 10:3533-8. 2010..LTQ-iQuant should make LTQ instruments and isobaric peptide tagging accessible to more proteomic researchers...
Malignant transformation initiated by Mll-AF9: gene dosage and critical target cellsWeili Chen
University of Minnesota Cancer Center, University of Minnesota, 420 Delaware Street S E, Minneapolis, MN 55455, USA
Cancer Cell 13:432-40. 2008..Mll-AF9 upregulated expression of 192 genes in both LSK and progenitor cells, but to higher levels in LSKs than in committed myeloid progenitors...
Differential gene expression detection using penalized linear regression models: the improved SAM statisticsBaolin Wu
Division of Biostatistics, School of Public Health, University of Minnesota, A460 Mayo Building, MMC 303, Minneapolis, MN 55455, USA
Bioinformatics 21:1565-71. 2005..biostat.umn.edu/~baolin/research CONTACT: baolin@biostat.umn.edu SUPPLEMENTARY INFORMATION: http://www.biostat.umn.edu/~baolin/research...
