Allan D Wu

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Asymmetric corticomotor excitability correlations in early Parkinson's disease
    Allan D Wu
    Department of Neurology, David Geffen School of Medicine, University of California Los Angeles UCLA, Los Angeles, California 90095 1769, USA
    Mov Disord 22:1587-93. 2007
  2. doi request reprint Interleaved practice enhances skill learning and the functional connectivity of fronto-parietal networks
    Chien Ho Janice Lin
    Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, 710 Westwood Plaza, Reed A 153, Los Angeles, California, USA
    Hum Brain Mapp 34:1542-58. 2013
  3. doi request reprint Brain-behavior correlates of optimizing learning through interleaved practice
    Chien Ho Janice Lin
    Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Neuroimage 56:1758-72. 2011
  4. doi request reprint Age related differences in the neural substrates of motor sequence learning after interleaved and repetitive practice
    Chien Ho Lin
    Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095 7332, USA
    Neuroimage 62:2007-20. 2012
  5. doi request reprint Enhanced motor learning in older adults is accompanied by increased bilateral frontal and fronto-parietal connectivity
    Chien Ho Janice Lin
    Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095 7332, USA
    Brain Connect 2:56-68. 2012
  6. doi request reprint Neural correlates of the contextual interference effect in motor learning: a transcranial magnetic stimulation investigation
    Chien Ho Janice Lin
    Division of Biokinesiology and Physical Therapy, School of Dentistry, University of Southern California, Los Angeles, CA, USA
    J Mot Behav 42:223-32. 2010
  7. doi request reprint Early semantic and phonological effects on temporal- and muscle-specific motor resonance
    Ingo G Meister
    Ahmanson Lovelace Brain Mapping Center, David Geffen School of Medicine, University of California, 660 Charles E Young Drive South, Los Angeles, CA 90095, USA
    Eur J Neurosci 36:2391-9. 2012
  8. pmc Neural correlate of the contextual interference effect in motor learning: a kinematic analysis
    Chien Ho Janice Lin
    School of Dentistry, University of Southern California, Los Angeles, CA, USA
    J Mot Behav 41:232-42. 2009
  9. doi request reprint Anodal tDCS to V1 blocks visual perceptual learning consolidation
    Megan A K Peters
    Department of Psychology, University of California, Los Angeles, Los Angeles, CA 90095 1563, USA
    Neuropsychologia 51:1234-9. 2013
  10. pmc Identification of potential neuromotor mechanisms of manual therapy in patients with musculoskeletal disablement: rationale and description of a clinical trial
    Beth E Fisher
    Neuroplasticity and Imaging Laboratory, Division of Biokinesiology and Physical Therapy at the School of Dentistry, University of Southern California, Los Angeles, California, USA
    BMC Neurol 9:20. 2009

Research Grants

Collaborators

Detail Information

Publications23

  1. ncbi request reprint Asymmetric corticomotor excitability correlations in early Parkinson's disease
    Allan D Wu
    Department of Neurology, David Geffen School of Medicine, University of California Los Angeles UCLA, Los Angeles, California 90095 1769, USA
    Mov Disord 22:1587-93. 2007
    ..These findings are consistent with an evolution of neurophysiologic correlates in early PD patients from a less to more symptomatic state...
  2. doi request reprint Interleaved practice enhances skill learning and the functional connectivity of fronto-parietal networks
    Chien Ho Janice Lin
    Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, 710 Westwood Plaza, Reed A 153, Los Angeles, California, USA
    Hum Brain Mapp 34:1542-58. 2013
    ....
  3. doi request reprint Brain-behavior correlates of optimizing learning through interleaved practice
    Chien Ho Janice Lin
    Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Neuroimage 56:1758-72. 2011
    ..This demonstrates that interleaved practice induces interrelated changes in both cortical hemodynamic responses and M1 excitability, which likely index the formation of enhanced memory traces and efficient long-term retrieval...
  4. doi request reprint Age related differences in the neural substrates of motor sequence learning after interleaved and repetitive practice
    Chien Ho Lin
    Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095 7332, USA
    Neuroimage 62:2007-20. 2012
    ..Older adults may engage compensatory mechanisms during interleaved practice such as increasing sensorimotor recruitment which in turn benefits learning...
  5. doi request reprint Enhanced motor learning in older adults is accompanied by increased bilateral frontal and fronto-parietal connectivity
    Chien Ho Janice Lin
    Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095 7332, USA
    Brain Connect 2:56-68. 2012
    ..These data suggest that though younger and older gain similar behavioral benefits from interleaved training, aging may alter the operation of brain networks underlying such optimized learning...
  6. doi request reprint Neural correlates of the contextual interference effect in motor learning: a transcranial magnetic stimulation investigation
    Chien Ho Janice Lin
    Division of Biokinesiology and Physical Therapy, School of Dentistry, University of Southern California, Los Angeles, CA, USA
    J Mot Behav 42:223-32. 2010
    ..Results contribute to knowledge of the critical and specific role that M1 plays in generating a learning advantage following high-interference practice conditions...
  7. doi request reprint Early semantic and phonological effects on temporal- and muscle-specific motor resonance
    Ingo G Meister
    Ahmanson Lovelace Brain Mapping Center, David Geffen School of Medicine, University of California, 660 Charles E Young Drive South, Los Angeles, CA 90095, USA
    Eur J Neurosci 36:2391-9. 2012
    ..Furthermore, the timing of the semantic effect suggests that motor activation during semantic processing is not an 'epiphenomenon' but rather is essential to the construction of meaning...
  8. pmc Neural correlate of the contextual interference effect in motor learning: a kinematic analysis
    Chien Ho Janice Lin
    School of Dentistry, University of Southern California, Los Angeles, CA, USA
    J Mot Behav 41:232-42. 2009
    ..The authors' data suggest that increased corticomotor activity during high CI practice may reflect preferential processing of the temporal parameter of the task...
  9. doi request reprint Anodal tDCS to V1 blocks visual perceptual learning consolidation
    Megan A K Peters
    Department of Psychology, University of California, Los Angeles, Los Angeles, CA 90095 1563, USA
    Neuropsychologia 51:1234-9. 2013
    ..These results show that applying tDCS to the visual cortex can modify consolidation of visual learning...
  10. pmc Identification of potential neuromotor mechanisms of manual therapy in patients with musculoskeletal disablement: rationale and description of a clinical trial
    Beth E Fisher
    Neuroplasticity and Imaging Laboratory, Division of Biokinesiology and Physical Therapy at the School of Dentistry, University of Southern California, Los Angeles, California, USA
    BMC Neurol 9:20. 2009
    ..However, the effect of treatment speed, as well as the specific mechanism and locus of CNS changes, remain unclear...
  11. pmc Noninvasive brain stimulation for Parkinson's disease and dystonia
    Allan D Wu
    Department of Neurology, University of California, Los Angeles, California 90095, USA
    Neurotherapeutics 5:345-61. 2008
    ..Nonetheless, the noninvasive nature, minimal side effects, positive effects in preliminary clinical studies, and increasing evidence for rational mechanisms make rTMS and tDCS attractive for ongoing investigation...
  12. doi request reprint Contextual interference effects in sequence learning for young and older adults
    Chien Ho Janice Lin
    Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, CA 90095, USA
    Psychol Aging 25:929-39. 2010
    ..Our study underscores the distinction between age-related effects on learning vs. performance, and offers practical implications for enhancing skill learning in older adults...
  13. pmc Do you see what I mean? Corticospinal excitability during observation of culture-specific gestures
    Istvan Molnar-Szakacs
    Center for the Biology of Creativity, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, California, USA Ahmanson Lovelace Brain Mapping Center, UCLA, Los Angeles, California, USA FPR UCLA Center for Culture, Brain and Development, UCLA, Los Angeles, California, USA Department of Psychiatry and Biobehavioral Sciences, UCLA, Los Angeles, California, USA
    PLoS ONE 2:e626. 2007
    ..The latter result cannot be interpreted simply as an effect of ethnic ingroup familiarity. Thus, a likely explanation of these findings is that motor resonance is modulated by interacting biological and cultural factors...
  14. ncbi request reprint Neuroimaging of nonmotor features of Parkinson's disease
    Choi Deblieck
    Ahmanson Lovelace Brain Mapping Center, University of California, Los Angeles, CA, USA
    Rev Neurol Dis 5:125-33. 2008
    ..These neuroimaging studies support a broader view of PD with early involvement in time and wider involvement of monoamine and cortical systems that may provide targets for novel therapies for nonmotor symptoms...
  15. pmc The effect of exercise training in improving motor performance and corticomotor excitability in people with early Parkinson's disease
    Beth E Fisher
    Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA 90089 9006, USA
    Arch Phys Med Rehabil 89:1221-9. 2008
    ....
  16. ncbi request reprint A preliminary study of fMRI-guided rTMS in the treatment of generalized anxiety disorder
    Alexander Bystritsky
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095 6968, USA
    J Clin Psychiatry 69:1092-8. 2008
    ..The goal of this pilot study was to evaluate whether functional magnetic resonance imaging (fMRI)-guided rTMS is effective in reducing symptoms of GAD...
  17. doi request reprint Fast estimation of transcranial magnetic stimulation motor threshold
    Feng Qi
    Neuroscience, University of Southern California, Los Angeles, California 90089, USA
    Brain Stimul 4:50-7. 2011
    ..Because the MT reflects cortical excitability, the TMS intensity needs to be adjusted according to the subject's MT at the beginning of every TMS session...
  18. ncbi request reprint The essential role of premotor cortex in speech perception
    Ingo G Meister
    Ahmanson Lovelace Brain Mapping Center, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA
    Curr Biol 17:1692-6. 2007
    ..These results show that the disruption of human premotor cortex impairs speech perception, thus demonstrating an essential role of premotor cortices in perceptual processes...
  19. ncbi request reprint Correlation between motor and phosphene thresholds: a transcranial magnetic stimulation study
    Choi Deblieck
    Ahmanson Lovelace Brain Mapping Center, UCLA, Los Angeles, California, USA
    Hum Brain Mapp 29:662-70. 2008
    ..They also provide a rationale for the use of easily obtained aMT to calibrate TMS intensities in brain mapping studies that employ TMS in cortical regions besides motor cortex...
  20. ncbi request reprint Motor cortex activation during treatment may predict therapeutic gains in paretic hand function after stroke
    Yun Dong
    Department of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA, USA
    Stroke 37:1552-5. 2006
    ..Functional brain imaging after stroke offers insight into motor network adaptations. This exploratory study examined whether motor cortical activation captured during arm-focused therapy can predict paretic hand functional gains...
  21. ncbi request reprint Functional neuroimaging and repetitive transcranial magnetic stimulation in Parkinson's disease
    Allan D Wu
    Ahmanson Lovelace Brain Mapping Center, University of California, Los Angeles UCLA and Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Rev Neurol Dis 4:1-9. 2007
    ....
  22. ncbi request reprint Effect of task practice order on motor skill learning in adults with Parkinson disease: a pilot study
    Chien Ho Janice Lin
    School of Dentistry, University of Southern California, Los Angeles, CA 90089, USA
    Phys Ther 87:1120-31. 2007
    ..Random practice of motor tasks has been shown to enhance motor learning. The purpose of this study was to investigate the effects of task practice order (random, blocked) on motor learning in adults with Parkinson disease (PD)...
  23. ncbi request reprint Reliability of intracortical and corticomotor excitability estimates obtained from the upper extremities in chronic stroke
    Lisa Koski
    Division of Geriatrics, Faculty of Medicine, Department of Neurology and Neurosurgery, McGill University, Canada
    Neurosci Res 58:19-31. 2007
    ..Due to high intrasubject variability, the use of some excitability parameters as indicators of functional neuroplasticity in response to treatment may be limited to interventions with large effect sizes...

Research Grants2