A H Wu

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. ncbi request reprint A multiethnic population-based study of smoking, alcohol and body size and risk of adenocarcinomas of the stomach and esophagus (United States)
    A H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, USA
    Cancer Causes Control 12:721-32. 2001
  2. ncbi request reprint HSD17B1 and CYP17 polymorphisms and breast cancer risk among Chinese women in Singapore
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
    Int J Cancer 104:450-7. 2003
  3. ncbi request reprint Soy intake and other lifestyle determinants of serum estrogen levels among postmenopausal Chinese women in Singapore
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90089, USA
    Cancer Epidemiol Biomarkers Prev 11:844-51. 2002
  4. ncbi request reprint Adolescent and adult soy intake and risk of breast cancer in Asian-Americans
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
    Carcinogenesis 23:1491-6. 2002
  5. ncbi request reprint Green tea and risk of breast cancer in Asian Americans
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
    Int J Cancer 106:574-9. 2003
  6. ncbi request reprint Hiatal hernia, reflux symptoms, body size, and risk of esophageal and gastric adenocarcinoma
    Anna H Wu
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, MC 9175, Los Angeles, CA 90089 9175, USA
    Cancer 98:940-8. 2003
  7. ncbi request reprint Plasma isoflavone levels versus self-reported soy isoflavone levels in Asian-American women in Los Angeles County
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles 90089 9175, USA
    Carcinogenesis 25:77-81. 2004
  8. ncbi request reprint Dietary heterocyclic amines and microsatellite instability in colon adenocarcinomas
    A H Wu
    Department of Preventive Medicine and Department of Pathology, University of Southern California, Keck School of Medicine, Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, Los Angeles, CA 90089 0251, USA
    Carcinogenesis 22:1681-4. 2001
  9. ncbi request reprint Tea intake, COMT genotype, and breast cancer in Asian-American women
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA 90089, USA
    Cancer Res 63:7526-9. 2003
  10. ncbi request reprint Role of Helicobacter pylori CagA+ strains and risk of adenocarcinoma of the stomach and esophagus
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, Keck School of Medicine, Los Angeles, CA 90089 9175, USA
    Int J Cancer 103:815-21. 2003

Research Grants

Detail Information

Publications76

  1. ncbi request reprint A multiethnic population-based study of smoking, alcohol and body size and risk of adenocarcinomas of the stomach and esophagus (United States)
    A H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, USA
    Cancer Causes Control 12:721-32. 2001
    ..We sought to determine the role of smoking, alcohol use, and body size characteristics in the etiology of esophageal, gastric cardia, and distal gastric adenocarcinomas...
  2. ncbi request reprint HSD17B1 and CYP17 polymorphisms and breast cancer risk among Chinese women in Singapore
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
    Int J Cancer 104:450-7. 2003
    ..41, 95% CI=1.56-3.72; RR=4.39, 95% CI=1.71-11.30, respectively). The latter gene-parity effects were especially pronounced in postmenopausal women...
  3. ncbi request reprint Soy intake and other lifestyle determinants of serum estrogen levels among postmenopausal Chinese women in Singapore
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90089, USA
    Cancer Epidemiol Biomarkers Prev 11:844-51. 2002
    ..Current smokers showed significantly higher E(2) levels (28%) than nonsmokers (P = 0.04). These findings are discussed in relation to the recent doubling of breast cancer incidence among Chinese women in Singapore...
  4. ncbi request reprint Adolescent and adult soy intake and risk of breast cancer in Asian-Americans
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
    Carcinogenesis 23:1491-6. 2002
    ..These results show that high soy intake in childhood in Asian-Americans is associated with reduced breast cancer risk. Risk may be further reduced by intake as an adult...
  5. ncbi request reprint Green tea and risk of breast cancer in Asian Americans
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
    Int J Cancer 106:574-9. 2003
    ..In summary, our results point to an important role of both green tea and soy intake in relation to breast cancer risk in Asian-American women...
  6. ncbi request reprint Hiatal hernia, reflux symptoms, body size, and risk of esophageal and gastric adenocarcinoma
    Anna H Wu
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, MC 9175, Los Angeles, CA 90089 9175, USA
    Cancer 98:940-8. 2003
    ..Since the 1970s, incidence rates of esophageal and gastric cardia adenocarcinoma have risen substantially. Reasons for the increasing trends are not well understood...
  7. ncbi request reprint Plasma isoflavone levels versus self-reported soy isoflavone levels in Asian-American women in Los Angeles County
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles 90089 9175, USA
    Carcinogenesis 25:77-81. 2004
    ..These results further strengthen our previous observation of an inverse association between soy intake and breast cancer risk in the Los Angeles Asian Breast Cancer Study...
  8. ncbi request reprint Dietary heterocyclic amines and microsatellite instability in colon adenocarcinomas
    A H Wu
    Department of Preventive Medicine and Department of Pathology, University of Southern California, Keck School of Medicine, Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, Los Angeles, CA 90089 0251, USA
    Carcinogenesis 22:1681-4. 2001
    ..These results provide a potential mechanism of linking HAA exposure and cigarette smoking to a specific subset of colon cancers...
  9. ncbi request reprint Tea intake, COMT genotype, and breast cancer in Asian-American women
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA 90089, USA
    Cancer Res 63:7526-9. 2003
    ..Reduction in risk was strongest among persons who had the low activity COMT alleles, suggesting these individuals were less efficient in eliminating tea catechins and may derive the most benefit from these compounds...
  10. ncbi request reprint Role of Helicobacter pylori CagA+ strains and risk of adenocarcinoma of the stomach and esophagus
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, Keck School of Medicine, Los Angeles, CA 90089 9175, USA
    Int J Cancer 103:815-21. 2003
    ..pylori reduces risk of esophageal and gastric cardia adenocarcinoma in this population. Our findings confirm the positive association between risk of distal gastric cancer and infection with H. pylori infection, especially CagA+ strains...
  11. ncbi request reprint Soy intake and risk of breast cancer in Asians and Asian Americans
    A H Wu
    Department of Preventive Medicine, University of Southern California, Los Angeles 90033 0800, USA
    Am J Clin Nutr 68:1437S-1443S. 1998
    ..Cross-sectional and longitudinal studies are necessary to investigate the longer-term relations between hormone concentrations and soy intake in women...
  12. ncbi request reprint Lifestyle determinants of 5alpha-reductase metabolites in older African-American, white, and Asian-American men
    A H Wu
    Departments of Preventive Medicine, University of Southern California, Los Angeles, California 90089 0251, USA
    Cancer Epidemiol Biomarkers Prev 10:533-8. 2001
    ..This difference may be related to the lower prostate cancer risk in Asian-Americans...
  13. ncbi request reprint A meta-analysis of soyfoods and risk of stomach cancer: the problem of potential confounders
    A H Wu
    Department of Preventive Medicine, University of Southern California, Los Angeles 90089 9175, USA
    Cancer Epidemiol Biomarkers Prev 9:1051-8. 2000
    ....
  14. ncbi request reprint Fiber intake and risk of adenocarcinomas of the esophagus and stomach
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, 1441 Eastlake Avenue, MS 44, Los Angeles, CA 90089 9175, USA
    Cancer Causes Control 18:713-22. 2007
    ..Since the 1970s, incidence rates for esophageal and gastric cardia adenocarcinomas have risen substantially for reasons that are not well understood. We sought to determine the role of dietary factors in these tumor types...
  15. ncbi request reprint Meta-analysis: dietary fat intake, serum estrogen levels, and the risk of breast cancer
    A H Wu
    Department of Preventive Medicine, University of Southern California Medical School, Los Angeles, USA
    J Natl Cancer Inst 91:529-34. 1999
    ....
  16. pmc Exposure misclassification bias in studies of environmental tobacco smoke and lung cancer
    A H Wu
    Department of Preventive Medicine, University of Southern California, Los Angeles, California 90089, USA
    Environ Health Perspect 107:873-7. 1999
    ....
  17. pmc Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium
    C L Pearce
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Br J Cancer 100:412-20. 2009
    ..CYP3A4 encodes a key enzyme in oestrogen metabolism and our finding between rs2740574 and risk of ovarian cancer suggests that this pathway may be involved in ovarian carcinogenesis. Additional follow-up is warranted...
  18. pmc Menstrual and reproductive factors and risk of breast cancer in Asian-Americans
    A H Wu
    Department of Preventive Medicine, University of Southern California, Los Angeles, 90033, USA
    Br J Cancer 73:680-6. 1996
    ..These results suggest that the lower rates of breast cancer in Asians must be largely as a result of other environmental/lifestyle factors...
  19. ncbi request reprint Does mammographic density reflect ethnic differences in breast cancer incidence rates?
    Zhengjia Chen
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
    Am J Epidemiol 159:140-7. 2004
    ..This study suggests that absolute but not percent mammographic density reflects the lower breast cancer incidence rates of Asian Americans in relation to those of African Americans and Whites...
  20. ncbi request reprint Mammographic density and breast cancer in three ethnic groups
    Giske Ursin
    Department of Preventive Medicine, University of California Keck School of Medicine, Los Angeles, California 90089, USA
    Cancer Epidemiol Biomarkers Prev 12:332-8. 2003
    ..Furthermore, our findings suggest that mammographic density is as strong a predictor of risk for African-American and Asian-American women as for white women...
  21. ncbi request reprint Estimated Asian adult soy protein and isoflavone intakes
    Mark Messina
    Department ofNutrition, School of PublicHealth, Loma Linda University, Loma Linda, CA, USA
    Nutr Cancer 55:1-12. 2006
    ..Evidence suggests that < or =10% of the Asian population consumes as much as 25 g of soy protein or 100 mg of isoflavones per day. The applicability of these findings for making soy intake recommendations for non-Asians is discussed...
  22. pmc A genome screen of families with multiple cases of prostate cancer: evidence of genetic heterogeneity
    C L Hsieh
    University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, CA, USA
    Am J Hum Genet 69:148-58. 2001
    ..The data provided little support for any of the putative prostate cancer-susceptibility genes identified in other linkage studies...
  23. ncbi request reprint Mismatch repair deficiency and CpG island hypermethylation in sporadic colon adenocarcinomas
    Z Xiong
    Departments of Surgery, University of Southern California, Keck School of Medicine, Los Angeles, CA 90089-9176, USA
    Cancer Epidemiol Biomarkers Prev 10:799-803. 2001
    ....
  24. pmc Soy intake and breast cancer risk in Singapore Chinese Health Study
    A H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90089, USA
    Br J Cancer 99:196-200. 2008
    ..These prospective findings suggest that approximately 10 mg of isoflavones per day, obtained in a standard serving of tofu, may have lasting beneficial effects against breast cancer development...
  25. pmc Effects of soy foods on ovarian function in premenopausal women
    A H Wu
    Department of Preventive Medicine, University of Southern California, School of Medicine, Los Angeles, USA
    Br J Cancer 82:1879-86. 2000
    ....
  26. ncbi request reprint Tamoxifen, soy, and lifestyle factors in Asian American women with breast cancer
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
    J Clin Oncol 25:3024-30. 2007
    ....
  27. ncbi request reprint Associations between soy, diet, reproductive factors, and mammographic density in Singapore Chinese women
    Giske Ursin
    University of Southern California, Los Angeles, CA 90089, USA
    Nutr Cancer 56:128-35. 2006
    ..Our results suggest that the effect of soy intake on percent mammographic density is moderate but possibly of clinical relevance...
  28. ncbi request reprint Diabetes and risk of breast cancer in Asian-American women
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90089, USA
    Carcinogenesis 28:1561-6. 2007
    ..08) than women without such a history after adjusting for BMI and WHR. Our results support the hypothesis that diabetes may have a role in the development of breast cancer, influencing risk via both sex hormone and insulin pathways...
  29. ncbi request reprint Body size, hormone therapy and risk of breast cancer in Asian-American women
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
    Int J Cancer 120:844-52. 2007
    ..017). The increased risk associated with high body weight was observed irrespective of HT use. Use of HT and high body size might have contributed to the rapid increase of breast cancer in Asian-Americans...
  30. ncbi request reprint Tea, hormone-related cancers and endogenous hormone levels
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90089 9175, USA
    Mol Nutr Food Res 50:160-9. 2006
    ..We pay special attention to some of the limitations of the human studies and discuss future research needs...
  31. ncbi request reprint Etiologic clues from the similarity of histology-specific trends in esophageal and lung cancers
    Myles G Cockburn
    Department of Preventive Medicine, USC Keck School of Medicine, Los Angeles, California, USA
    Cancer Causes Control 16:1065-74. 2005
    ..Squamous cell lung cancers, while caused by smoking, are believed to be caused by different constituents of tobacco smoke than lung adenocarcinomas. Smoking is also a risk factor for esophageal cancers...
  32. pmc A common genetic risk factor for colorectal and prostate cancer
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Nat Genet 39:954-6. 2007
    ..Comprehensive testing in the region uncovered variants capturing significant additional risk. Our results show that variants at 8q24 have different effects on cancer development that depend on the tissue type...
  33. doi request reprint Markers of inflammation and risk of ovarian cancer in Los Angeles County
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA 90089 9175, USA
    Int J Cancer 124:1409-15. 2009
    ..The NSAID finding was unexpected and suggests that factors associated with inflammation are associated with ovarian cancer risk. This result needs confirmation with careful attention to the reasons for NSAID use...
  34. doi request reprint Increased ovarian cancer risk associated with menopausal estrogen therapy is reduced by adding a progestin
    Celeste Leigh Pearce
    Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Cancer 115:531-9. 2009
    ....
  35. pmc Green tea, soy, and mammographic density in Singapore Chinese women
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    Cancer Epidemiol Biomarkers Prev 17:3358-65. 2008
    ..52). Our findings suggest that both regular green tea and high soy intake may have beneficial effects on the breast; the effect of green tea on PMD may be stronger than the effect of soy...
  36. ncbi request reprint Comprehensive association testing of common genetic variation in DNA repair pathway genes in relationship with breast cancer risk in multiple populations
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
    Hum Mol Genet 17:825-34. 2008
    ..The methods utilized in this study, applied to multiple populations, provide a framework for testing in association studies in diverse populations...
  37. doi request reprint Dietary patterns and breast cancer risk in Asian American women
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90089, USA
    Am J Clin Nutr 89:1145-54. 2009
    ..The role of diet as a cause of breast cancer in Asian Americans has not been adequately studied...
  38. pmc Hormone therapy, DNA methylation and colon cancer
    Anna H Wu
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA, USA
    Carcinogenesis 31:1060-7. 2010
    ..055) and increased DNA methylation of ESR1 in the 'tumorous' colonic tissues (P = 0.056). These findings on DNA methylation and hormone therapy use need confirmation in larger studies...
  39. pmc Sleep duration, melatonin and breast cancer among Chinese women in Singapore
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    Carcinogenesis 29:1244-8. 2008
    ..However, data are inconclusive from the three studies conducted in Western populations on sleep duration and breast cancer risk...
  40. doi request reprint Comprehensive evaluation of ESR2 variation and ovarian cancer risk
    Celeste Leigh Pearce
    USC Norris Comprehensive Cancer Center and Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90089, USA
    Cancer Epidemiol Biomarkers Prev 17:393-6. 2008
    ..28-11.73; P = 0.016). Haplotype D was also reported by the BPC3 to be associated with increased risk of breast cancer. This haplotype warrants further investigation to rule out any effect with invasive ovarian cancer risk...
  41. pmc Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations
    Jing He
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, USC Norris Comprehensive Cancer Center, Harlyne Norris Research Tower, 1450 Biggy Street, Los Angeles, CA 90033, USA
    Cancer Epidemiol Biomarkers Prev 20:70-81. 2011
    ..Genome-wide association studies (GWAS) in populations of European ancestry have identified several loci that confer an increased risk of colorectal cancer (CRC)...
  42. pmc Greatly increased occurrence of breast cancers in areas of mammographically dense tissue
    Giske Ursin
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA
    Breast Cancer Res 7:R605-8. 2005
    ..We addressed this question by studying ductal carcinoma in situ (DCIS), as revealed by microcalcifications...
  43. ncbi request reprint A controlled 2-mo dietary fat reduction and soy food supplementation study in postmenopausal women
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, Keck School of Medicine, Los Angeles, CA 90089 9175, USA
    Am J Clin Nutr 81:1133-41. 2005
    ..Low intake of dietary fat and high intake of soy foods have been suggested to partly explain the lower breast cancer rates in Asia, perhaps because of lower endogenous estrogens...
  44. ncbi request reprint Hormonal factors and the risk of invasive ovarian cancer: a population-based case-control study
    Malcolm C Pike
    USC Norris Comprehensive Cancer Center, Keck School of Medicine, Department of Preventive Medicine, University of Southern California, Los Angeles, California 90033, USA
    Fertil Steril 82:186-95. 2004
    ..To examine the influence of hormone-related factors on the risk of invasive epithelial ovarian cancer (ovarian cancer)...
  45. ncbi request reprint Is residual confounding a reasonable explanation for the apparent protective effects of beta-carotene found in epidemiologic studies of lung cancer in smokers?
    Daniel O Stram
    Department of Preventive Medicine, School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Am J Epidemiol 155:622-8. 2002
    ..Appropriate cohort studies of lung cancer in smokers, utilizing biomarkers of smoking, are needed and are presently ongoing...
  46. ncbi request reprint Tea and circulating estrogen levels in postmenopausal Chinese women in Singapore
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90089 9175, USA
    Carcinogenesis 26:976-80. 2005
    ..Larger studies are needed to confirm results from this cross-sectional study and to better understand the potentially differing effect of black and green tea on circulating estrogen levels and ultimately on the risk of breast cancer...
  47. ncbi request reprint Clarifying the PROGINS allele association in ovarian and breast cancer risk: a haplotype-based analysis
    Celeste Leigh Pearce
    Department of Preventive Medicine, Norris Comprehensive Cancer Center, University of Southern California, Keck School of Medicine, Los Angeles, CA 90089, USA
    J Natl Cancer Inst 97:51-9. 2005
    ..We set out to refine the association between common variation at the PGR gene locus and these two diseases...
  48. ncbi request reprint Prevention of cancers of the breast, endometrium and ovary
    Malcolm C Pike
    USC Norris Cancer Center, Los Angeles, CA, USA
    Oncogene 23:6379-91. 2004
    ..Some recent epidemiological findings in endometrial and ovarian cancer suggest new avenues for possible chemoprevention of these cancers...
  49. pmc Epidemiology of soy exposures and breast cancer risk
    A H Wu
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089 9175, USA
    Br J Cancer 98:9-14. 2008
    ..8 and 0.15 mg per day, respectively. Thus, the evidence to date, based largely on case-control studies, suggest that soy food intake in the amount consumed in Asian populations may have protective effects against breast cancer...
  50. ncbi request reprint Physical activity and breast cancer risk among Asian-American women in Los Angeles: a case-control study
    Dongyun Yang
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Cancer 97:2565-75. 2003
    ..To the authors' knowledge, there have been few studies published to date regarding physical activity patterns and breast cancer risk in Asian and Asian-American women...
  51. ncbi request reprint Occupational physical activity and risk of adenocarcinomas of the esophagus and stomach
    Cheryl Vigen
    Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089 9175, USA
    Int J Cancer 118:1004-9. 2006
    ..Future studies with more complete information on occupational and recreational physical activity are needed to confirm and further investigate the suggested protective effect of physical activity on these tumor types...
  52. doi request reprint Progesterone and estrogen receptors in pregnant and premenopausal non-pregnant normal human breast
    DeShawn Taylor
    Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA
    Breast Cancer Res Treat 118:161-8. 2009
    ..Short-term changes in PRA expression while the chemoprevention is being administered may be a more useful marker...
  53. doi request reprint Perspectives on the soy-breast cancer relation
    Mark Messina
    Department of Nutrition, School of Public, Health, Loma Linda University, Loma Linda, CA, USA
    Am J Clin Nutr 89:1673S-1679S. 2009
    ....
  54. pmc Progesterone receptor variation and risk of ovarian cancer is limited to the invasive endometrioid subtype: results from the Ovarian Cancer Association Consortium pooled analysis
    C L Pearce
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA 90089, USA
    Br J Cancer 98:282-8. 2008
    ..80, 95% CI 0.62-1.04, P=0.100). These data suggest that while these three variants in the PGR are not associated with ovarian cancer overall, the PROGINS variant may play a modest role in risk of endometrioid ovarian cancer...
  55. pmc Dense breast stromal tissue shows greatly increased concentration of breast epithelium but no increase in its proliferative activity
    Debra Hawes
    Department of Pathology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, Los Angeles, CA 90089, USA
    Breast Cancer Res 8:R24. 2006
    ....
  56. pmc Consortium analysis of 7 candidate SNPs for ovarian cancer
    Susan J Ramus
    Translational Research Laboratory, University College London EGA Institute for Women s Health, London, United Kingdom
    Int J Cancer 123:380-8. 2008
    ..These null results for SNPs identified from relatively large initial studies shows the importance of replicating associations by a consortium approach...
  57. ncbi request reprint Recreational physical activity and risk of postmenopausal breast cancer in a large cohort of US women
    Alpa V Patel
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30329 4251, USA
    Cancer Causes Control 14:519-29. 2003
    ..Our findings are consistent with other studies that show lower risk of postmenopausal breast cancer associated with regular physical activity...
  58. ncbi request reprint Carbohydrates and colorectal cancer risk among Chinese in North America
    Marilyn J Borugian
    Cancer Control Research, British Columbia Cancer Agency, Vancouver, British Columbia, V5Z 4E6 Canada
    Cancer Epidemiol Biomarkers Prev 11:187-93. 2002
    ....
  59. ncbi request reprint Re: Beta-carotene and lung cancer: a lesson for future chemoprevention investigations?
    Daniel O Stram
    J Natl Cancer Inst 95:E4. 2003
  60. ncbi request reprint Association of galactose-1-phosphate uridyltransferase activity and N314D genotype with the risk of ovarian cancer
    Marc T Goodman
    Epidemiology Section, Cancer Etiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu 96813, USA
    Am J Epidemiol 156:693-701. 2002
    ..42, 1.41). This study did not support the hypothesis that reduced galactose metabolism is a risk factor for ovarian cancer, although increased GALT activity attenuated the inverse association of oral contraceptive pill use with risk...
  61. ncbi request reprint Segregation analysis of prostate cancer in 1,719 white, African-American and Asian-American families in the United States and Canada
    Gail Gong
    Stanford University School of Medicine, Department of Health Research and Policy, CA 94305 5405, USA
    Cancer Causes Control 13:471-82. 2002
    ..However, higher observed frequencies in brothers than fathers may merely reflect the strong temporal changes in US incidence rates...
  62. ncbi request reprint Association of dairy products, lactose, and calcium with the risk of ovarian cancer
    Marc T Goodman
    Cancer Etiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI 96813, USA
    Am J Epidemiol 156:148-57. 2002
    ..003), although a nonsignificant inverse gradient in risk was also found in relation to calcium supplement intake. These results suggest that intake of low-fat milk, calcium, or lactose may reduce the risk of ovarian cancer...
  63. doi request reprint A promoter polymorphism in the CASP8 gene is not associated with cancer risk
    Christopher A Haiman
    Nat Genet 40:259-60; author reply 260-1. 2008
  64. ncbi request reprint Reproductive factors and epithelial ovarian cancer risk by histologic type: a multiethnic case-control study
    Ko Hui Tung
    Cancer Etiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu 96813, USA
    Am J Epidemiol 158:629-38. 2003
    ..Mucinous tumors, both borderline and invasive, were more common in Asian women than in Caucasian and other women. Our data suggest that histologic types of epithelial ovarian cancer are etiologically distinct...
  65. ncbi request reprint Association of dietary vitamin A, carotenoids, and other antioxidants with the risk of ovarian cancer
    Ko Hui Tung
    Cancer Etiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI 96813, USA
    Cancer Epidemiol Biomarkers Prev 14:669-76. 2005
    ..Questions still remain regarding the effects of confounding factors, such as menopause, tobacco smoking, and alcohol drinking, on the association between antioxidants and ovarian cancer development...
  66. ncbi request reprint Effect of anovulation factors on pre- and postmenopausal ovarian cancer risk: revisiting the incessant ovulation hypothesis
    Ko Hui Tung
    Cancer Etiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI 96813, USA
    Am J Epidemiol 161:321-9. 2005
    ....
  67. ncbi request reprint Urinary estrogen metabolites and their ratio among Asian American women
    Roni T Falk
    Environmental Epidemiology Branch, National Cancer Institute, 6120 Executive Boulevard, MSC 7234, Suite 7070, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 14:221-6. 2005
    ..Our study suggests that the ratio of 2-OHE(1):16alpha-OHE(1) may be a marker for lifestyle influences on estrogen metabolism associated with westernization...
  68. ncbi request reprint Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer
    Simon A Gayther
    Translational Research Laboratories, University College London, London, United Kingdom
    Cancer Res 67:3027-35. 2007
    ..This study highlights the need for multicenter collaborations for genetic association studies...
  69. ncbi request reprint Risk of early-onset prostate cancer in relation to germ line polymorphisms of the vitamin D receptor
    Ingrid Oakley-Girvan
    Department of Health Research and Policy, Stanford University School of Medicine, HRP Redwood Building, T204, Stanford, CA 94305 5405, USA
    Cancer Epidemiol Biomarkers Prev 13:1325-30. 2004
    ..S. Whites. If the FokI association noted here were causal, this difference could account for some of the disease burden among African Americans and some of the excess risk in African Americans compared with Whites...
  70. ncbi request reprint Aggregation of ovarian cancer with breast, ovarian, colorectal, and prostate cancer in first-degree relatives
    Ko Hui Tung
    Cancer Etiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI 96813, USA
    Am J Epidemiol 159:750-8. 2004
    ..Study findings suggest that ovarian cancer aggregates with several common cancers in family members...
  71. ncbi request reprint Secondhand smoke exposure in adulthood and risk of lung cancer among never smokers: a pooled analysis of two large studies
    Paul Brennan
    International Agency for Research on Cancer, Lyon, France
    Int J Cancer 109:125-31. 2004
    ..Clear dose-response relationships consistent with a causal association were observed between exposure to secondhand smoke from spousal, workplace and social sources and the development of lung cancer among never smokers...
  72. ncbi request reprint Prediagnostic C-peptide and risk of prostate cancer
    Marilyn J Borugian
    Cancer Control Research, British Columbia Cancer Agency, 675 West 10th Avenue, Vancouver, British Columbia, Canada V5Z 1L3
    Cancer Epidemiol Biomarkers Prev 16:2164-5. 2007
  73. pmc Stage at diagnosis and survival in a multiethnic cohort of prostate cancer patients
    Ingrid Oakley-Girvan
    Stanford University School of Medicine, Stanford, California 94305 5405, USA
    Am J Public Health 93:1753-9. 2003
    ..We evaluated the effects of socioeconomic status and comorbidity on stage of disease and survival among 1509 population-based prostate cancer patients...
  74. doi request reprint Nonsteroidal anti-inflammatory drugs and risk of esophageal and gastric adenocarcinomas in Los Angeles County
    Lei Duan
    Division of Population Sciences, City of Hope National Medical Center, 1500 East Duarte Road, Duarte, CA 91010, USA
    Cancer Epidemiol Biomarkers Prev 17:126-34. 2008
    ..Yet, data on potential confounding effects by upper gastrointestinal tract (UGI) disorders on adenocarcinomas of the UGI are limited...
  75. ncbi request reprint Infertility, fertility drugs, and ovarian cancer: a pooled analysis of case-control studies
    Roberta B Ness
    University of Pittsburgh School of Public Health, Pittsburgh, PA 15261, USA
    Am J Epidemiol 155:217-24. 2002
    ..10, 2.71) and unknown cause of infertility (OR = 1.19, 95% CI: 1.00, 1.40) increased cancer risk. These data suggest a role for specific biologic causes of infertility, but not for fertility drugs in overall risk for ovarian cancer...
  76. doi request reprint Prostate cancer risk in relation to insulin-like growth factor (IGF)-I and IGF-binding protein-3: a prospective multiethnic study
    Marilyn J Borugian
    Cancer Control Research, British Columbia Cancer Agency, 675 West 10th Avenue, Vancouver, British Columbia, Canada
    Cancer Epidemiol Biomarkers Prev 17:252-4. 2008

Research Grants5

  1. DIETARY AND GENETIC DETERMINANTS OF MAMMOGRAPHIC DENSITY
    Anna Wu; Fiscal Year: 2007
    ..abstract_text> ..