Research Topics
Species | Jonathan L WrightSummaryAffiliation: University of Washington Country: USA Publications
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Publications
Positive surgical margins at radical prostatectomy predict prostate cancer specific mortalityJonathan L Wright
Department of Urology, University of Washington School of Medicine, Seattle, Washington, USA
J Urol 183:2213-8. 2010..Using a large, population based national cancer registry we evaluated the risk of prostate cancer specific mortality associated with margin status...
Laparoscopy and the management of blunt bladder traumaJonathan L Wright
Department of Urology, University of Washington, Seattle, WA, USA
J Trauma 63:1165-6. 2007
Quality of life in young men after radical prostatectomyJ L Wright
Department of Urology, University of Washington School of Medicine, Seattle, WA 98195, USA
Prostate Cancer Prostatic Dis 11:67-73. 2008..Baseline scores are strongly associated with post-RP scores and severity of declines. Current relationships and use of sexual aids have significant roles in post-RP bother...
CYP17 polymorphisms and prostate cancer outcomesJonathan L Wright
Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
Prostate 70:1094-101. 2010..However, studies relating prostate cancer outcomes with CYP17 gene variants have conflicting results. In this study we analyzed Single Nucleotide Polymorphisms (SNPs) spanning the CYP17 gene for association with PCa survival...
The association between extent of lymphadenectomy and survival among patients with lymph node metastases undergoing radical cystectomyJonathan L Wright
Department of Urology, University of Washington School of Medicine, Seattle, WA 98195, USA
Cancer 112:2401-8. 2008..The objective of this study was to describe the association between extent of lymphadenectomy and survival in lymph node-positive patients who underwent radical cystectomy...
Metformin use and prostate cancer in Caucasian men: results from a population-based case-control studyJonathan L Wright
Department of Urology, University of Washington School of Medicine, Seattle, WA, USA
Cancer Causes Control 20:1617-22. 2009..In this study, we explore the relationship between metformin use and PCa risk in a population-based case-control study...
Effect of collecting duct histology on renal cell cancer outcomeJonathan L Wright
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
J Urol 182:2595-9. 2009..Recent surgical series of the condition showed conflicting results. We used an American population based data set to compare the survival experience of patients with collecting duct vs clear cell renal cell carcinoma...
Prostate cancer specific mortality and Gleason 7 disease differences in prostate cancer outcomes between cases with Gleason 4 + 3 and Gleason 3 + 4 tumors in a population based cohortJonathan L Wright
Department of Urology, University of Washington School of Public Health, Seattle, Washington 98195, USA
J Urol 182:2702-7. 2009..In this population based cohort we determined prostate cancer outcomes at different Gleason scores, particularly the different Gleason 7 patterns...
Male pattern baldness and prostate cancer risk in a population-based case-control studyJonathan L Wright
Department of Urology, University of Washington School of Medicine, Seattle, WA, United States
Cancer Epidemiol 34:131-5. 2010..Studies exploring the relationship between the two conditions have been inconclusive. Using a population-based, case-control study of PCa, we explore the relationship between early-onset MPB and PCa risk...
AMACR polymorphisms, dietary intake of red meat and dairy and prostate cancer riskJonathan L Wright
Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
Prostate 71:498-506. 2011..AMACR is also a tumor tissue biomarker over-expressed in PCa. In this study, we explored the potential relationship between AMACR polymorphisms, red meat/dairy intake, and PCa risk...
The effect of demographic and clinical factors on the relationship between BMI and PSA levelsJonathan L Wright
Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
Prostate 71:1631-7. 2011..In this study we evaluated the potential confounding effect of these factors on the obesity-PSA relationship and evaluated the association between these factors and PSA level...
Differences in survival among patients with urachal and nonurachal adenocarcinomas of the bladderJonathan L Wright
Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
Cancer 107:721-8. 2006..The current study compares disease-specific characteristics and survival associated with urachal and nonurachal primary bladder adenocarcinomas...
Differences in survival among patients with sarcomatoid carcinoma, carcinosarcoma and urothelial carcinoma of the bladderJonathan L Wright
Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
J Urol 178:2302-6; discussion 2307. 2007..We investigated the survival of patients with the 2 tumor subtypes compared to survival in those with urothelial carcinoma...
Hospital-level variation in the quality of urologic cancer surgeryJohn L Gore
Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
Cancer 118:987-96. 2012..The authors of this report examined hospital-level variation in outcomes after inpatient urologic oncology procedures...
Impact of male hormonal contraception on prostate androgens and androgen action in healthy men: a randomized, controlled trialElahe A Mostaghel
Division of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
J Clin Endocrinol Metab 97:2809-17. 2012..Male hormonal contraception (MHC) combines hypothalamic-pituitary-gonadal axis blockade with exogenous androgen delivery to maintain extragonadal androgen end-organ effects. Concern exists that MHC may adversely impact prostate health...
American Association for the Surgery of Trauma Organ Injury Scale for kidney injuries predicts nephrectomy, dialysis, and death in patients with blunt injury and nephrectomy for penetrating injuriesJames K Kuan
Department of Urology, University of Washington Medical Center, Seattle, Washington 98104, USA
J Trauma 60:351-6. 2006..CONCLUSION: The AAST injury scale for kidney predicts for morbidity in blunt and penetrating renal injury and for mortality in blunt injury. Thus, we continue to support its use as a clinical and research tool...
Expression of SLCO transport genes in castration-resistant prostate cancer and impact of genetic variation in SLCO1B3 and SLCO2B1 on prostate cancer outcomesJonathan L Wright
Department of Urology, University of Washington, Seattle, WA, USA
Cancer Epidemiol Biomarkers Prev 20:619-27. 2011....
Experience improves staging accuracy of endorectal magnetic resonance imaging in prostate cancer: what is the learning curve?Kalyan C Latchamsetty
Sections of Urology and Radiology, Virginia Mason Medical Center, Seattle, Washington 98101, USA
Can J Urol 14:3429-34. 2007..In order to assess the learning curve for endorectal MRI interpretation, we compared two cohorts of patients with high-risk prostate who underwent endorectal MRI at a center with limited prior exposure to this imaging modality...
Radiographic and clinical predictors of bladder rupture in blunt trauma patients with pelvic fractureGreg Avey
Department of Radiology, University of Washington School of Medicine, Box 359960, 325 Ninth Avenue, Seattle, WA 98104, USA
Acad Radiol 13:573-9. 2006..In addition to hematuria, specific pelvic injury patterns are associated with bladder rupture. If validated, a clinical prediction rule derived from this data has the potential to guide the care of the blunt trauma patient...
Primary scrotal cancer: disease characteristics and increasing incidenceJonathan L Wright
Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
Urology 72:1139-43. 2008..Using a population-based cancer registry, we describe the demographic and pathologic characteristics of scrotal cancer and report the incidence trends over time...
Hospital volume and 90-day mortality risk after radical cystectomy: a population-based cohort studyMichael P Porter
Division of Urology, VA Puget Sound Health Care System, Department of Urology, University of Washington, 1660 S Columbian Way, S 112 GU, Seattle, WA 98108, USA
World J Urol 29:73-7. 2011..In this study, we examine the relationship between hospital cystectomy volume and 90-day mortality in a population-based cohort of patients undergoing cystectomy for bladder cancer...
Predictors of upper tract urothelial cell carcinoma after primary bladder cancer: a population based analysisJonathan L Wright
Department of Urology, University of Washington School of Medicine, Seattle, Washington, USA
J Urol 181:1035-9; discussion 1039. 2009..We determined the cumulative incidence of secondary upper tract tumor development after primary bladder cancer and risk factors for secondary upper tract tumors using contemporary population based data...
An abnormal digital rectal examination is an independent predictor of Gleason > or =7 prostate cancer in men undergoing initial prostate biopsy: a prospective study of 790 menLester S Borden
Department of Urology, Virginia Mason Medical Center, University of Washington, 1100 9th Avenue, Seattle, WA 98101, USA
BJU Int 99:559-63. 2007....
Renal injury mechanisms of motor vehicle collisions: analysis of the crash injury research and engineering network data setJames K Kuan
Department of Urology, University of Washington, School of Medicine, Seattle, Washington 98102, USA
J Urol 178:935-40; discussion 940. 2007..We identified possible collision patterns and vehicle interior components that may have a role in kidney injury following motor vehicle collision...
Specific fracture configurations predict sexual and excretory dysfunction in men and women 1 year after pelvic fractureJonathan L Wright
Department of Urology, Surgery, Pediatrics and Epidemiology, University of Washington School of Medicine, Harborview Medical Center and Harborview Injury Prevention Research Center, Seattle, Washington 98104, USA
J Urol 176:1540-5; discussion 1545. 2006..Our data highlight the need for further study of dysfunction following pelvic trauma and interventions to decrease the risk of long-term disability...
Improved prostate cancer detection with anterior apical prostate biopsiesJonathan L Wright
Department of Urology, University of Washington Medical Center, Seattle, WA 98195-6510, USA
Urol Oncol 24:492-5. 2006..CONCLUSION: In our experience, the anterior apical biopsies increase the detection of prostate cancer on transrectal ultrasound-guided biopsies. Further study on incorporating this site into the biopsy scheme is indicated...
Circumcision and the risk of prostate cancerJonathan L Wright
Department of Urology, University of Washington School of Medicine, Seattle, WA, USA
Cancer 118:4437-43. 2012..In particular, sexually transmitted infections (STIs) have been implicated in PCa etiology, and studies have found that the risk of acquiring a STI can be reduced with circumcision. Therefore, circumcision may reduce PCa risk...
Dihydrotestosterone administration does not increase intraprostatic androgen concentrations or alter prostate androgen action in healthy men: a randomized-controlled trialStephanie T Page
Division of Metabolism, Endocrinology, and Nutrition, University of Washington School of Medicine, Box 357138, 1959 NE Pacific Street, Seattle, Washington 98195, USA
J Clin Endocrinol Metab 96:430-7. 2011..Exogenous androgens raise serum DHT concentrations, but their effects on the prostate are not clear...
Laparoscopic partial nephrectomy: comparison of transperitoneal and retroperitoneal approachesJonathan L Wright
Department of Urology, University of Washington Medical Center, Seattle, Washington 98195, USA
J Urol 174:841-5. 2005..For polar or posterolateral masses the retroperitoneal approach is preferred. The transperitoneal approach is best suited to anterior and medial lesions...
Renal artery pseudoaneurysm after laparoscopic partial nephrectomyJonathan L Wright
Department of Urology, University of Washington School of Medicine, Seattle, Washington, USA
Urology 66:1109. 2005..The patients were treated with selective angioembolization of the pseudoaneurysm. The etiology and management of this potentially life-threatening condition are discussed...
Tumor lysis syndrome in a patient with metastatic, androgen independent prostate cancerJonathan L Wright
Department of Urology, University of Washington, WA, USA
Int J Urol 12:1012-3. 2005..It is rarely described in patients with solid tumors. We report a case of TLS in a patient with metastatic adenocarcinoma of the prostate after treatment with paclitaxel chemotherapy...
Admission for nephrolithiasis in pregnancy and risk of adverse birth outcomesMia A Swartz
Department of Urology, University of Washington, Seattle, Washington 98195, USA
Obstet Gynecol 109:1099-104. 2007..The goal of this study was to describe the association between these outcomes and admission for nephrolithiasis during pregnancy...
Quality-of-life assessment in patients with bladder cancerJonathan L Wright
Department of Urology, University of Washington, Seattle, WA 98108, USA
Nat Clin Pract Urol 4:147-54. 2007..Prospective studies with appropriate adjustment for confounding factors, which use validated and disease-specific questionnaires, are needed for HRQOL research on bladder cancer...
What is the most cost-effective treatment for 1 to 2-cm bulbar urethral strictures: societal approach using decision analysisJonathan L Wright
Department of Urology, Harborview Medical Center, University of Washington Medical Center, Seattle, Washington, USA
Urology 67:889-93. 2006..Future prospective, multicenter studies of DVIU and urethroplasty outcomes would help enhance the accuracy of our model...
Intermittent androgen deprivation: clinical experience and practical applicationsJonathan L Wright
Department of Urology, University of Washington, Seattle, WA 98195, USA
Urol Clin North Am 33:167-79, vi. 2006..This article discusses the theoretical benefits and rationale of IAD and reviews the completed and on-going IAD trials. Finally, the controversies, practical applications, and future directions of IAD are addressed...
Maternal risk factors for congenital urinary anomalies: results of a population-based case-control studyMargarett Shnorhavorian
Department of Urology, University of Washington School of Medicine, Seattle, WA, USA
Urology 78:1156-61. 2011..The purpose of this study was to examine the association between maternal risk factors and CUTA in a population-based case-control study...
Renal and extrarenal predictors of nephrectomy from the national trauma data bankJonathan L Wright
Department of Urology, University of Washington School of Medicine, Seattle, Washington, USA
J Urol 175:970-5; discussion 975. 2006..The need for surgery on other intra-abdominal injuries increases the risk of nephrectomy to a lesser extent. In cases of blunt trauma severe renal injury usually necessitates nephrectomy...
Long-term use of supplemental vitamins and minerals does not reduce the risk of urothelial cell carcinoma of the bladder in the VITamins And Lifestyle studyJames M Hotaling
Department of Urology, University of Washington School of Medicine, Seattle, Washington 98103, USA
J Urol 185:1210-5. 2011....
Newer potential biomarkers in prostate cancerJonathan L Wright
Department of Urology, University of Washington School of Medicine Seattle, WA
Rev Urol 9:207-13. 2007..This article reviews some of the promising developments in biomarkers...
