Research Topics
Genomes and GenesSpecies | Clinton B WrightSummaryAffiliation: University of Miami Country: USA Publications
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Publications
Session II: Mechanisms of age-related cognitive change and targets for intervention: neural circuits, networks, and plasticityCharles DeCarli
Department of Neurology and Center for Neuroscience, University of California, Davis, USA
J Gerontol A Biol Sci Med Sci 67:747-53. 2012..Moreover, this understanding will assist in promoting the utilization of existing interventions, such as lifestyle and therapeutic modifiers of vascular disease...- The aging mind: vascular health in normal cognitive agingJessica R L Warsch
Evelyn F McKnight Center for Age related Memory Loss, Department of Neurology, Miller School of Medicine, University of Miami, Miami, Florida 33133, USA
J Am Geriatr Soc 58:S319-24. 2010..This brief survey of the literature reviews evidence of the roles of subclinical vascular brain damage and exposure to cerebrovascular risk factors in normal cognitive aging... 
Inflammatory biomarkers of vascular risk as correlates of leukoariosisClinton B Wright
Department of Neurology, Miller School of Medicine, University of Miami, Evelyn F McKnight Center for Age related Memory Loss, Miami, FL 33136, USA
Stroke 40:3466-71. 2009..White matter hyperintensities (WMH) seen on brain MRI scans are associated with vascular risk factors and an increased risk of incident stroke, but their relation to inflammatory biomarkers is unclear...- Mediterranean diet and white matter hyperintensity volume in the Northern Manhattan StudyHannah Gardener
Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
Arch Neurol 69:251-6. 2012..To examine the association between a Mediterranean-style diet (MeDi) and brain magnetic resonance imaging white matter hyperintensity volume (WMHV)... - Dietary sodium and risk of stroke in the Northern Manhattan studyHannah Gardener
Department of Neurology, University of Miami, Miami, FL, USA
Stroke 43:1200-5. 2012..Although sodium intake has been linked to vascular disease by direct relationship with hypertension, few studies have supported an association with stroke risk... - Ethnic differences in carotid artery diameter and stiffness: the Northern Manhattan StudyMatthew S Markert
Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33101, USA
Atherosclerosis 219:827-32. 2011..Our objective was to investigate differences in carotid artery diameter and stiffness between race/ethnic groups, and examine whether these race/ethnic differences were age-dependent... - Ideal cardiovascular health predicts lower risks of myocardial infarction, stroke, and vascular death across whites, blacks, and hispanics: the northern Manhattan studyChuanhui Dong
Department of Neurology, University of Miami, CRB 13, 1120 NW 14th St, Miami, FL 33136, USA
Circulation 125:2975-84. 2012..This study sought to evaluate the relationship between the number of ideal CVH metrics and cardiovascular risk, overall and by event subtype, in a multiethnic community-based prospective cohort... - Mediterranean-style diet and risk of ischemic stroke, myocardial infarction, and vascular death: the Northern Manhattan StudyHannah Gardener
Evelyn F McKnight Brain Institute, Department of Neurology, Miller School of Medicine, University of Miami, FL 33136, USA
Am J Clin Nutr 94:1458-64. 2011..Data on blacks and Hispanics in the United States are lacking, and to our knowledge only one study has examined a Mediterranean-style diet (MeDi) in relation to stroke... - The metabolic syndrome and cognitive performance: the Northern Manhattan StudyJulio R Vieira
Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
Neuroepidemiology 37:153-9. 2011..We hypothesized that MetS would be associated with lower Mini-Mental State Examination (MMSE) scores in a multi-ethnic population, and that MetS is a better predictor of cognition than its individual components or diabetes... - Serum adiponectin in relation to race-ethnicity and vascular risk factors in the Northern Manhattan StudyHannah Gardener
Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, USA
Metab Syndr Relat Disord 11:46-55. 2013..We examined the cross-sectional association between adiponectin, vascular risk factors and race-ethnicity in the population-based Northern Manhattan Study (NOMAS)... - Baseline and longitudinal increases in diastolic blood pressure are associated with greater white matter hyperintensity volume: the northern Manhattan studyJustin Marcus
Brain Institute, Department of Neurology, University of Miami, Miami, FL 33136, USA
Stroke 42:2639-41. 2011..Few studies have included Hispanics, who are at greater risk of stroke and dementia than non-Hispanic whites. We examined BP in relation to WMHV in a stroke-free cohort... - Genetic loci for blood lipid levels identified by linkage and association analyses in Caribbean HispanicsChuanhui Dong
Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, USA
J Lipid Res 52:1411-9. 2011..0001) for other lipid traits with SNPs in or near CDH13, SUMF2, TLE3, FAH, ARNT2, TSHZ3, ZNF343, RPL7AL2, and TMC3. Further studies are warranted to perform in-depth investigations of functional genetic variants in these regions... - Race-ethnic differences of sleep symptoms in an elderly multi-ethnic cohort: the Northern Manhattan StudyAlberto R Ramos
Department of Neurology, Miller School of Medicine, University of Miami Miami, FL 33136, USA
Neuroepidemiology 37:210-5. 2011..Sleep disorders are associated with stroke and may vary among elderly Hispanics, Blacks and Whites. We evaluated differences in sleep symptoms by race-ethnicity in an elderly population-based urban community sample... - Insulin resistance and risk of ischemic stroke among nondiabetic individuals from the northern Manhattan studyTatjana Rundek
Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
Arch Neurol 67:1195-200. 2010..Whether insulin resistance predicts ischemic stroke (IS) is still a matter of debate... - White matter hyperintensities and subclinical infarction: associations with psychomotor speed and cognitive flexibilityClinton B Wright
Division of Stroke and Critical Care, Department of Neurology, College of Physicians and Surgeons of Columbia University, NI Room 640, 710 W168th Street, New York, NY 10032, USA
Stroke 39:800-5. 2008..We examined white matter hyperintensity volume (WMHV) and subclinical infarction (no history of clinical stroke; SI) in relation to performance on tests of sequencing, cognitive flexibility, and sensorimotor ability... - Adiponectin and carotid intima-media thickness in the northern Manhattan studyHannah Gardener
Department of Neurology, University of Miami, Miami, FL 33136, USA
Stroke 43:1123-5. 2012..We examined the relationship between adiponectin and IMT, a marker of atherosclerosis, in a multiethnic cohort study of stroke risk factors... - Early depressed mood after stroke predicts long-term disability: the Northern Manhattan Stroke Study (NOMASS)Joshua Z Willey
Department of Neurology, University of California, San Francisco, CA, USA
Stroke 41:1896-900. 2010..Depression is highly prevalent after stroke and may influence recovery. We aimed to determine whether depressed mood acutely after stroke predicts subsequent disability and mortality... - Association between northern Manhattan study global vascular risk score and successful agingJessica R L Warsch
Evelyn F McKnight Brain Institute, Department of Neurology, Leonard M Miller School of Medicine, University of Miami, Miami, Florida
J Am Geriatr Soc 61:519-24. 2013.... - Adiponectin and risk of vascular events in the Northern Manhattan studyHannah Gardener
Department of Neurology, Miller School of Medicine, University of Miami, 1120 NW 14th Street, Miami, FL 33136, USA
Atherosclerosis 226:483-9. 2013.... - Reported alcohol consumption and cognitive decline: The northern Manhattan studyClinton B Wright
Division of Stroke and Critical Care, Department of Neurology, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
Neuroepidemiology 27:201-7. 2006..Moderate alcohol intake may slow cognitive decline, and both vascular and neurodegenerative mechanisms have been implicated... - Chronic kidney disease is associated with white matter hyperintensity volume: the Northern Manhattan Study (NOMAS)Minesh Khatri
Division of Stroke and Critical Care, Department of Neurology, College of Physicians and Surgeons of Columbia University, NI Room 640, 710 W 168th Street, New York, NY 10032, USA
Stroke 38:3121-6. 2007..Few studies have explored the relationship between chronic kidney disease and white matter hyperintensities... - Alcohol intake, carotid plaque, and cognition: the Northern Manhattan StudyClinton B Wright
Division of Stroke and Critical Care, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
Stroke 37:1160-4. 2006..Few studies to clarify the importance of vascular disease have included direct measures of atherosclerosis or minority populations at higher risk of vascular disease and dementia... - Diet soft drink consumption is associated with an increased risk of vascular events in the Northern Manhattan StudyHannah Gardener
Department of Neurology, University of Miami Miller School of Medicine, Clinical Research Building, Miami, FL 33136, USA
J Gen Intern Med 27:1120-6. 2012..Diet and regular soft drinks have been associated with diabetes and the metabolic syndrome, and regular soft drinks with coronary heart disease... - Genomewide linkage and peakwide association analyses of carotid plaque in Caribbean HispanicsChuanhui Dong
Evelyn F McKnight Center for Age related Memory Loss, Department of Neurology, Miller Schoolof Medicine, University of Miami, Miami, FL, USA
Stroke 41:2750-6. 2010..Atherosclerosis is a complex subclinical cardiovascular disorder with a substantial genetic component. This study sought to identify genetic loci influencing carotid plaque in 2 independent samples... - Association of serum soluble receptor for advanced glycation end-products with subclinical cerebrovascular disease: the Northern Manhattan Study (NOMAS)Barry I Hudson
Division of Surgical Science, Department of Surgery, College of Physicians and Surgeons, Columbia University, New York, NY, USA
Atherosclerosis 216:192-8. 2011..We hypothesized that sRAGE levels are associated with subclinical cerebrovascular disease in an ethnically diverse population... - Infectious burden and cognitive function: the Northern Manhattan StudyMira Katan
Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA
Neurology 80:1209-15. 2013..e., Chlamydia pneumoniae, Helicobacter pylori, cytomegalovirus, and herpes simplex virus 1 and 2) associated with vascular risk in the prospective Northern Manhattan Study (NOMAS), would also be associated with cognition... - Total homocysteine is associated with white matter hyperintensity volume: the Northern Manhattan StudyClinton B Wright
Department of Neurology, Columbia University College of Physicians and Surgeons and the Mailman School of Public Health, New York, NY, USA
Stroke 36:1207-11. 2005..White matter hyperintensities may be a risk factor for both, but studies of the relationship between tHcy and quantitative measures of white matter hyperintensity volume (WMHV) are lacking, especially in minority populations... 
Ischemic stroke subtype incidence among whites, blacks, and Hispanics: the Northern Manhattan StudyHalina White
Department of Neurology, College of Physicians and Surgeons, USA
Circulation 111:1327-31. 2005..32 (95% CI, 1.48 to 3.63); and cardioembolic stroke, 1.42 (95% CI, 0.97 to 2.09). CONCLUSIONS: The high ischemic stroke incidence among blacks and Hispanics compared with whites is due to higher rates of all ischemic stroke subtypes...- Dolichoectasia-an evolving arterial diseaseJose Gutierrez
Evelyn F McKnight Brain Institute, Department of Neurology, Miller School of Medicine, University of Miami, 1120 NW 14th Street, Suite 1387, Miami, FL 33136, USA
Nat Rev Neurol 7:41-50. 2011..In this article, we provide a comprehensive review of current knowledge regarding dolichoectasia, and highlight gaps in our knowledge to aid future research... - Acute confusional syndrome from a dural arteriovenous fistulaEmily R Lantz
Department of Neurology, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
Neurosurgery 65:E208-9; discussion E9. 2009..We describe a case of an acute confusional state associated with a right parietal dural arteriovenous fistula... - Dementia with cerebrovascular diseaseClinton B Wright
Columbia University College of Physicians and Surgeons, Department of Neurology, New York, NY 10032, USA
Sci Aging Knowledge Environ 2006:dn1. 2006..In some cases of mixed dementia, the pathological involvement of AD may be the principal contributory cause of the cognitive symptoms, and in others, the vascular changes may give the greater contribution...