Research Topics
Species | A L WrightSummaryAffiliation: University of Arizona Country: USA Publications
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Publications
Epidemiology of asthma and recurrent wheeze in childhoodAnne L Wright
Arizona Respiratory Center, Department of Pediatrics, University of Arizona, Tucson, AZ 85724, USA
Clin Rev Allergy Immunol 22:33-44. 2002..Additional research regarding these relationships is essential, both to elucidate possible causal mechanisms and to provide insight into the primary prevention of asthma...- Using cultural knowledge in health promotion: breastfeeding among the NavajoA L Wright
Department of Pediatrics, University of Arizona, Tucson, USA
Health Educ Behav 24:625-39. 1997.... - Analysis of epidemiological studies: facts and artifactsAnne L Wright
Arizona Respiratory Center and Department of Pediatrics, The University of Arizona, Tucson, AZ 85724, USA
Paediatr Respir Rev 3:198-204. 2002..The Tucson Children's Respiratory Study is used to exemplify these lessons and to illustrate the advantages of cohort studies in investigating a complex disease... 
Factors influencing the relation of infant feeding to asthma and recurrent wheeze in childhoodA L Wright
Respiratory Sciences Center, Arizona Health Sciences Center and Department of Pediatrics and Steele Memorial Children s Research Center, University of Arizona, Tucson, Arizona, USA
Thorax 56:192-7. 2001..The relationship between infant feeding and childhood asthma is controversial. This study tested the hypothesis that the relation between breast feeding and childhood asthma is altered by the presence of maternal asthma...- The rise of breastfeeding in the United StatesA L Wright
Department of Pediatrics, Arizona Health Sciences Center, Tucson, Arizona, USA
Pediatr Clin North Am 48:1-12. 2001..quot; Efforts to improve breastfeeding rates need to make visible the wider cultural context in which infant-feeding choices are made and alter components that make it difficult for US women to feed their infants optimally... - Gender differences in academic advancement: patterns, causes, and potential solutions in one US College of MedicineAnne L Wright
Arizona Respiratory Center and Department of Pediatrics, Tucson, AZ 85724, USA
Acad Med 78:500-8. 2003..This study tested hypotheses about why gender disparities exist in salary, rank, track, leadership, and perceptions of campus climate at one academic center, the University of Arizona College of Medicine, Tucson... - Relation of two different subtypes of croup before age three to wheezing, atopy, and pulmonary function during childhood: a prospective studyJ A Castro-Rodriguez
Respiratory Sciences Center, University of Arizona, College of Medicine, Tucson, Arizona, USA
Pediatrics 107:512-8. 2001..The objective of this study was to determine the long-term outcome of croup (as diagnosed by a physician) in early life... - Relation between infantile colic and asthma/atopy: a prospective study in an unselected populationJ A Castro-Rodriguez
Arizona Respiratory Center, University of Arizona, College of Medicine, Tucson, Arizona, USA
Pediatrics 108:878-82. 2001..To assess whether children with history of infantile colic may be at increased risk of subsequently developing asthma and/or atopy... - Increased incidence of asthmalike symptoms in girls who become overweight or obese during the school yearsJ A Castro-Rodriguez
Respiratory Sciences Center, University of Arizona, College of Medicine, Tucson, AZ 85724, USA
Am J Respir Crit Care Med 163:1344-9. 2001..In females, becoming overweight or obese between 6 and 11 yr of age increases the risk of developing new asthma symptoms and increased bronchial responsiveness during the early adolescent period... - Dog exposure in infancy decreases the subsequent risk of frequent wheeze but not of atopyS T Remes
Respiratory Sciences Center, Arizona Health Sciences Center, University of Arizona, Tucson 85724, USA
J Allergy Clin Immunol 108:509-15. 2001..Nevertheless, early pet exposure does not seem to significantly influence the development of allergic sensitization... - Two subphenotypes of childhood asthma that differ in maternal and paternal influences on asthma riskM Halonen
Respiratory Sciences Center and Departments of Pharmacology and Pediatrics, University of Arizona Health Sciences Center, Tucson, Arizona, USA
Am J Respir Crit Care Med 160:564-70. 1999..Thus, dividing asthma in children at age 6 into Alternaria-positive and Alternaria-negative groups identifies subphenotypes that are further distinguished by differences in phenotypic markers and parental influences... 
Relation of early antibiotic use to childhood asthma: confounding by indication?Y Su
Arizona Respiratory Center, College of Public Health, Department of Pharmacology, University of Arizona, Tucson, AZ 85724, USA
Clin Exp Allergy 40:1222-9. 2010..Findings from studies of the relation between early antibiotic use and subsequent asthma have been inconsistent, which may be attributable to methodologic issues...- Dynamic changes in sensitization to specific aeroallergens in children raised in a desert environmentD A Stern
The Arizona Respiratory Center and The Departments of Pharmacology and Pediatrics, The University of Arizona HSC, Tucson, AZ 85724, USA
Clin Exp Allergy 34:1563-669. 2004..CONCLUSION: This study shows that sensitization to individual aeroallergens in childhood is dynamic and indicates the limitation of single point assessment of skin test reactivity... - The association of allergic sensitization in mother and child in breast-fed and formula-fed infantsA L Wright
Department of Pediatrics, and Arizona Health Sciences Center, University of Arizona, Tucson 85724, USA
Adv Exp Med Biol 501:249-55. 2001..These results suggest that milk from allergic mothers either promotes a Th2 type immune response or suppresses Th1 immune response in the child... - Familial aggregation and segregation analysis of eosinophil levelsC J Holberg
Respiratory Sciences Center, Department of Pediatrics, University of Arizona Health Sciences Center, Tucson, Arizona
Am J Respir Crit Care Med 160:1604-10. 1999..Holberg CJ, Halonen M, Wright AL, Martinez FD. Familial aggregation and segregation analysis of eosinophil levels... - Reduced interferon gamma production and soluble CD14 levels in early life predict recurrent wheezing by 1 year of ageStefano Guerra
Arizona Respiratory Center, College of Medicine, University of Arizona, Tucson, Arizona 85724-5030, USA
Am J Respir Crit Care Med 169:70-6. 2004..031). Our findings from a longitudinal cohort suggest that impaired IFNgamma production at 3 months and reduced plasma-sCD14 levels at birth significantly increase the risk of developing recurrent wheezing in the first year of life... - Th1/Th2 patterns and balance in cytokine production in the parents and infants of a large birth cohortMarilyn Halonen
Department of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ 85724, USA
J Immunol 182:3285-93. 2009.... - Parental asthma as a risk factor for the development of early skin test sensitization in childrenElena Crestani
Arizona Respiratory Center, Health Sciences Center, Tucson, Ariz, USA
J Allergy Clin Immunol 113:284-90. 2004..The strong association between allergic sensitization and asthma is at least in part explained by an increased susceptibility to allergen sensitization in subjects predisposed to asthma... - The relation of rhinitis to recurrent cough and wheezing: a longitudinal studyDuane L Sherrill
Mel and Enid Zuckerman College of Public Health, University of Arizona, Arizona, USA
Respir Med 99:1377-85. 2005..Recurrent cough can be a clinical manifestation of rhinitis. However, it remains unclear if the association between rhinitis and recurrent cough among children is independent of asthma... - Relation of beta2-adrenoceptor polymorphisms at codons 16 and 27 to persistence of asthma symptoms after the onset of pubertyStefano Guerra
Arizona Respiratory Center, University of Arizona, 1501 N Campbell Ave, PO Box 245030, Tucson, AZ 85724 5030, USA
Chest 128:609-17. 2005..It has long been recognized that many children with asthma outgrow the disease after the onset of puberty, but little is known about genetic factors influencing this outcome... - Outcome of asthma and wheezing in the first 6 years of life: follow-up through adolescenceWayne J Morgan
Arizona Respiratory Center, P.O. Box 245030, Tucson, Arizona 85724, USA
Am J Respir Crit Care Med 172:1253-8. 2005..CONCLUSION: Patterns of wheezing prevalence and levels of lung function are established by age 6 yr and do not appear to change significantly by age 16 yr in children who start having asthma-like symptoms during the preschool years... - Factors influencing gender differences in the diagnosis and treatment of asthma in childhood: the Tucson Children's Respiratory StudyAnne L Wright
Arizona Respiratory Center, Arizona Health Sciences Center, Tucson, Arizona 85724, USA
Pediatr Pulmonol 41:318-25. 2006..8 vs. 1.6 years, P < 0.005). These findings indicate that gender differences in the diagnosis and treatment of asthma cannot be explained completely by differences in symptom prevalence and frequency... - Environmental determinants of and impact on childhood asthma by the bacterial community in household dustRaina M Maier
Department of Soil, Water and Environmental Science, University of Arizona, 429 Shantz Building 38, Tucson, AZ 85721, USA
Appl Environ Microbiol 76:2663-7. 2010..0103) and specific IgE (P = 0.0184). Our findings suggest that specific bacterial populations within the community are associated with either risk or protection from asthma... - Compensation in academic medicine: progress toward gender equityAnne L Wright
Arizona Respiratory Center, Tucson, AZ, USA
J Gen Intern Med 22:1398-402. 2007..Studies have documented substantial salary disparities between women and men in academic medicine. While various strategies have been proposed to increase equity, to our knowledge, no interventions have been evaluated... - Is there a common cold constitution?Thomas M Ball
Department of Pediatrics and the Steele Memorial Children s Research Center, University of Arizona College of Medicine, Tucson 85724 5073, USA
Ambul Pediatr 2:261-7. 2002..Constitutional factors might play a role in the susceptibility to clinical illness during the common cold. This study seeks to determine if the likelihood of developing frequent common colds persists during childhood... - Influence of attendance at day care on the common cold from birth through 13 years of ageThomas M Ball
Department of Pediatrics, University of Arizona College of Medicine, 1501 N Campbell Ave, PO Box 245073, Tucson, AZ 85724 5073, USA
Arch Pediatr Adolesc Med 156:121-6. 2002..To describe trends in the occurrence of the common cold during the first 13 years of life among children who attended different childcare settings early in life... - The epidemiology of the atopic child: who is at risk for what?Anne L Wright
Arizona Respiratory Center, Department of Pediatrics, University of Arizona, Tucson, Arizona 85724, USA
J Allergy Clin Immunol 113:S2-7. 2004..Clearly, all these factors should be evaluated in identifying the appropriate prevention measures and treatment for the child who is at risk for allergic disease... - Prenatal factors associated with the development of eczema in the first year of lifeMargaret Kurzius-Spencer
Arizona Respiratory Center, University of Arizona, Tucson, AZ 85724-5030, USA
Pediatr Allergy Immunol 16:19-26. 2005..32, CI 0.16-0.63, p <0.001). Our findings from this cohort study suggest that in utero factors, including maternal IgE, colds, and eczema, may influence the risk of infant eczema... - Navajo perceptions of asthma and asthma medications: clinical implicationsD van Sickle
Respiratory Sciences Center, Arizona Health Sciences Center, Tucson, Arizona, USA
Pediatrics 108:E11. 2001..In addition, excessive reliance on emergency treatments and the high rates of hospital admissions suggest that asthma is undertreated in this group of Navajo patients... - Persistence of asthma symptoms during adolescence: role of obesity and age at the onset of pubertyStefano Guerra
Arizona Respiratory Center, University of Arizona, 1501 North Campbell Avenue, P.O. Box 245030, Tucson, AZ 85724-5030, USA
Am J Respir Crit Care Med 170:78-85. 2004..Our findings from a population-based longitudinal cohort challenge the commonly held view that asthma usually remits during adolescence... - Wheezing and bronchial hyper-responsiveness in early childhood as predictors of newly diagnosed asthma in early adulthood: a longitudinal birth-cohort studyDebra A Stern
Arizona Respiratory Center, University of Arizona, Tucson, AZ, USA
Lancet 372:1058-64. 2008..Incidence of asthma increases during early adulthood. We aimed to estimate the contributions of sex and early life factors to asthma diagnosed in young adults... - Effect of breastfeeding on lung function in childhood and modulation by maternal asthma and atopyTheresa W Guilbert
Arizona Respiratory Center, Department of Pediatrics, University of Arizona, Tucson, Arizona, USA
Am J Respir Crit Care Med 176:843-8. 2007..The protective effect of breastfeeding on early respiratory infections is well established, but its relationship to the development of subsequent asthma remains controversial... - Influence of early day-care exposure on total IgE levels through age 3 yearsJanet Rothers
Arizona Respiratory Center, University of Arizona, Tucson, AZ 85724, USA
J Allergy Clin Immunol 120:1201-7. 2007..Early day care is inversely associated with asthma and atopy in later childhood, but its association with early immunologic markers of asthma risk is not known... - Effects of parental smoking on interferon gamma production in childrenGina Tebow
Arizona Respiratory Center, University of Arizona, 1501 N Campbell Ave, PO Box 245030, Tucson, AZ 85724 5030, USA
Pediatrics 121:e1563-9. 2008..In a population-based birth cohort, we sought to determine the relation of parental smoking, as assessed prospectively since pregnancy, to the child's interferon gamma and interleukin 4 production at 11 years of age... - Association of IL-5 cytokine production and in vivo IgE levels in infants and parentsElena Crestani
Arizona Respiratory Center, University of Arizona Health Sciences Center, University of Arizona, Tucson, AZ 85724 5030, USA
J Allergy Clin Immunol 120:820-6. 2007..Regulation of IgE might occur in relation to adaptive immune cytokine production. In vitro studies have assessed the role of individual cytokines in regulating IgE production in human subjects... - Some hidden costs of faculty turnover in clinical departments in one academic medical centerErnest P Schloss
Clinical Coordinating and Planning, The University of Arizona College of Medicine, Tucson, Arizona 85724, USA
Acad Med 84:32-6. 2009..To calculate the costs of clinical faculty turnover in clinical departments at The University of Arizona College of Medicine, including some aspects of lost clinical income... - Health, place and childhood asthma in southwest AlaskaSteven Wind
Arizona Respiratory Center, Arizona Health Sciences Center, University of Arizona, 501 North Campbell Avenue, P. O. Box 245073, Tucson, AZ 85724-5073, USA
Soc Sci Med 58:75-88. 2004.... - Poor airway function in early infancy and lung function by age 22 years: a non-selective longitudinal cohort studyDebra A Stern
Arizona Respiratory Center, University of Arizona, Tucson, Arizona, USA
Lancet 370:758-64. 2007..We aimed to investigate whether lung function in early adulthood is, in turn, affected by airway function measured shortly after birth... - The differential effect of genetic variation on soluble CD14 levels in human plasma and milkStefano Guerra
Arizona Respiratory Center, College of Medicine, University of Arizona, Tuscon, AZ 85724 5030, USA
Am J Reprod Immunol 52:204-11. 2004..The protein CD14 is a pattern recognition receptor for bacterial lipopolysaccharide (LPS). Whether genetic variation has the same influence on soluble CD14 (sCD14) levels in human plasma and milk remains to be determined... - Th2 cell-selective enhancement of human IL13 transcription by IL13-1112C>T, a polymorphism associated with allergic inflammationLisa Cameron
Functional Genomics Laboratory, and Arizona Respiratory Center, College of Medicine, University of Arizona, 1501 North Campbell Avenue, Tucson, AZ 85724, USA
J Immunol 177:8633-42. 2006..Our findings suggest the nuclear milieu dictates the functional outcome of genetic variation... - Qualitative study of the use of traditional healing by asthmatic Navajo familiesDavid Van Sickle
Arizona Respiratory Center and Department of Pediatrics, University of Arizona, College of Medicine, Tucson 85724, USA
Am Indian Alsk Native Ment Health Res 11:1-18. 2003..The use of traditional healing for asthma is influenced by beliefs about the disease and factors specific to the individual, including their local social, economic, and cultural context... - Low IFN-gamma production in the first year of life as a predictor of wheeze during childhoodDebra A Stern
The Arizona Respiratory Center, University of Arizona, Tucson, AZ 85724, USA
J Allergy Clin Immunol 120:835-41. 2007..Diminished cytokine production in infancy has been associated with an increased risk for allergen sensitization and early-life wheeze... - Tucson Children's Respiratory Study: 1980 to presentLynn M Taussig
National Jewish Medical and Research Center, Denver, USA
J Allergy Clin Immunol 111:661-75; quiz 676. 2003..Future TCRS studies will focus on (1) factors in infancy and early childhood that relate to persistent asthma and atopy; (2) role of genetic factors in persistent asthma; and (3) determinants of lung function decline in early adult life... - TGF-beta in human milk is associated with wheeze in infancyWendy H Oddy
Department of Nutrition, Dietetics, and Food Science, University of Technology, Perth, Australia
J Allergy Clin Immunol 112:723-8. 2003..CONCLUSION: This analysis shows that the dose of TGF-beta1 received from milk has a significant relationship with infant wheeze, which might account for at least some of the protective effect of breast-feeding against wheeze... - The role of active family nutritional support in Navajos' type 2 diabetes metabolic controlCarolyn Epple
Sonoma State University, Rohnert Park, California 94928, USA
Diabetes Care 26:2829-34. 2003..We examined if active family nutritional support is associated with improved metabolic outcomes for Diné (Navajo) individuals living with type 2 diabetes...