GEORGE F WOOTENSummaryAffiliation: University of Virginia Country: USA Publications
Research Grants
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Detail Information
Publications
The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD studyJeanne C Latourelle
Department of Neurology, Boston University School of Medicine, Boston University, Boston, MA, USA
BMC Med 6:32. 2008..Studies of the penetrance of LRRK2 mutations have produced a wide range of estimates, possibly due to differences in study design and recruitment, including in particular differences between samples of familial PD versus sporadic PD...
Anatomy and function of dopamine receptors: understanding the pathophysiology of fluctuations in Parkinson's diseaseG F Wooten
Department of Neurology, University of Virginia Health System, Box 800394, Charlottesville, VA 22908, USA
Parkinsonism Relat Disord 8:79-83. 2001..These mechanisms result in excessive, pathological inhibition of basal ganglia output neurons in the GPi producing dyskinesias and the short duration response...
Are men at greater risk for Parkinson's disease than women?G F Wooten
Department of Neurology, Box 800394, University Health System, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
J Neurol Neurosurg Psychiatry 75:637-9. 2004..5 times greater in men than women. Possible reasons for this increased risk of Parkinson's disease in men are toxicant exposure, head trauma, neuroprotection by oestrogen, mitochondrial dysfunction, or X linkage of genetic risk factors...
Research Grants
- Parkinson's Disease Neuroprotection Clinical TrialGEORGE WOOTEN; Fiscal Year: 2007..Our team is experienced, productive, and fully able to meet the requirements to become a Clinical Cente for the Parkinson's Disease Neuroprotection Trial. ..
