Bradford A Woodworth

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Surfactant protein B detection and gene expression in chronic rhinosinusitis
    Bradford A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
    Laryngoscope 117:1296-301. 2007
  2. ncbi Sinonasal surfactant protein A1, A2, and D gene expression in cystic fibrosis: a preliminary report
    Bradford A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
    Otolaryngol Head Neck Surg 137:34-8. 2007
  3. ncbi Murine tracheal and nasal septal epithelium for air-liquid interface cultures: a comparative study
    Bradford A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
    Am J Rhinol 21:533-7. 2007
  4. doi An in vitro model of Pseudomonas aeruginosa biofilms on viable airway epithelial cell monolayers
    Bradford A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA
    Am J Rhinol 22:235-8. 2008
  5. doi Transient receptor potential vanilloid type 4 channel expression in chronic rhinosinusitis
    Geeta Bhargave
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
    Am J Rhinol 22:7-12. 2008
  6. doi Physiologic alterations in the murine model after nasal fungal antigenic exposure
    Ayesha N Khalid
    Division of Otolaryngology Head and Neck Surgery, Pennsylvania State College of Medicine, Philadelphia, PA, USA
    Otolaryngol Head Neck Surg 139:695-701. 2008
  7. doi Baby shampoo nasal irrigations for the symptomatic post-functional endoscopic sinus surgery patient
    Alexander G Chiu
    Division of Rhinology, Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Am J Rhinol 22:34-7. 2008
  8. doi Spontaneous CSF leaks: a paradigm for definitive repair and management of intracranial hypertension
    Bradford A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA 19104 4206, USA
    Otolaryngol Head Neck Surg 138:715-20. 2008
  9. ncbi Intraoperative IGS/CT updates for complex endoscopic frontal sinus surgery
    Sri Kiran Chennupati
    Division of Rhinology, Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA
    ORL J Otorhinolaryngol Relat Spec 70:268-70. 2008
  10. ncbi Murine nasal septa for respiratory epithelial air-liquid interface cultures
    Marcelo B Antunes
    University of Pennsylvania, Philadelphia, PA, USA
    Biotechniques 43:195-6, 198, 200 passim. 2007

Collaborators

Detail Information

Publications27

  1. ncbi Surfactant protein B detection and gene expression in chronic rhinosinusitis
    Bradford A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
    Laryngoscope 117:1296-301. 2007
    ..Our objective was to detect the presence of SP-B, measure alterations in several forms of chronic rhinosinusitis (CRS), and localize cellular protein expression...
  2. ncbi Sinonasal surfactant protein A1, A2, and D gene expression in cystic fibrosis: a preliminary report
    Bradford A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
    Otolaryngol Head Neck Surg 137:34-8. 2007
    ..To measure alterations in SPA1, A2, and D gene expression in various forms of inflammatory chronic rhinosinusitis (CRS)...
  3. ncbi Murine tracheal and nasal septal epithelium for air-liquid interface cultures: a comparative study
    Bradford A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
    Am J Rhinol 21:533-7. 2007
    ..Our hypothesis is that the murine nasal septum is a better source of ciliated respiratory epithelium to develop respiratory epithelial air-liquid interface models...
  4. doi An in vitro model of Pseudomonas aeruginosa biofilms on viable airway epithelial cell monolayers
    Bradford A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA
    Am J Rhinol 22:235-8. 2008
    ..To better understand the interactions of bacterial biofilms with respiratory epithelium, we describe an in vitro model of biofilm sinusitis by establishing mature biofilms on airway epithelial air-liquid interface cultures...
  5. doi Transient receptor potential vanilloid type 4 channel expression in chronic rhinosinusitis
    Geeta Bhargave
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
    Am J Rhinol 22:7-12. 2008
    ..Thus, the goal of this study was to establish the expression pattern of TRPV4 in human sinonasal mucosa and determine whether expression is altered in chronic rhinosinusitis (CRS)...
  6. doi Physiologic alterations in the murine model after nasal fungal antigenic exposure
    Ayesha N Khalid
    Division of Otolaryngology Head and Neck Surgery, Pennsylvania State College of Medicine, Philadelphia, PA, USA
    Otolaryngol Head Neck Surg 139:695-701. 2008
    ..To determine whether a recently developed murine model of fungus-induced sinonasal inflammation demonstrated alterations in ciliary activity and expression of inflammatory cytokines...
  7. doi Baby shampoo nasal irrigations for the symptomatic post-functional endoscopic sinus surgery patient
    Alexander G Chiu
    Division of Rhinology, Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Am J Rhinol 22:34-7. 2008
    ....
  8. doi Spontaneous CSF leaks: a paradigm for definitive repair and management of intracranial hypertension
    Bradford A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA 19104 4206, USA
    Otolaryngol Head Neck Surg 138:715-20. 2008
    ..To report our outcomes with the repair of spontaneous cerebrospinal fluid (CSF) leaks and to demonstrate how management of underlying intracranial hypertension improves outcomes...
  9. ncbi Intraoperative IGS/CT updates for complex endoscopic frontal sinus surgery
    Sri Kiran Chennupati
    Division of Rhinology, Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA
    ORL J Otorhinolaryngol Relat Spec 70:268-70. 2008
    ..We describe the potential applications of xCAT, a new intraoperative mobile volume CT scanner and its utility in providing surgical navigation updates in the operating room...
  10. ncbi Murine nasal septa for respiratory epithelial air-liquid interface cultures
    Marcelo B Antunes
    University of Pennsylvania, Philadelphia, PA, USA
    Biotechniques 43:195-6, 198, 200 passim. 2007
    ..The nasal septum increases the yield of respiratory epithelial cells up to 8-fold...
  11. doi Endoscopic closure of CSF rhinorrhea: 193 cases over 21 years
    Caroline A Banks
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA
    Otolaryngol Head Neck Surg 140:826-33. 2009
    ..Endoscopic repair of cerebrospinal fluid (CSF) leaks has become a routine approach. This study describes endoscopic closure of a large series over 21 years, focusing on management, surgical technique, and long-term outcomes...
  12. ncbi Endoscopic management of frontal sinus mucoeceles with anterior table erosion
    Bradford A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Rhinology 46:231-7. 2008
    ..To describe the endoscopic management of frontal sinus mucoeceles with anterior table erosion. Previous hardware exposure and subsequent contour defects were also assessed...
  13. doi Endoscopic repair of supraorbital ethmoid cerebrospinal fluid leaks
    Michael T Purkey
    Division of Rhinology, Department of Otorhinolaryngology, Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    ORL J Otorhinolaryngol Relat Spec 71:93-8. 2009
    ..To examine the clinical and anatomical characteristics of patients with supraorbital ethmoid (SOE) cerebrospinal fluid (CSF) leaks and encephaloceles and identify specific considerations unique to their management...
  14. doi Cigarette smoke condensate inhibits transepithelial chloride transport and ciliary beat frequency
    Noam A Cohen
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Laryngoscope 119:2269-74. 2009
    ..The present study investigates the consequences of cigarette smoke exposure on ciliary function and transepithelial chloride (Cl(-)) secretion, a major determinant of ASL...
  15. ncbi Clinical outcomes of endoscopic and endoscopic-assisted resection of inverted papillomas: a 15-year experience
    Bradford A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
    Am J Rhinol 21:591-600. 2007
    ..The aim of this retrospective study was to review the experience with the endoscopic and endoscopic-assisted resection of IPs at a major academic tertiary care facility and assess long-term outcomes...
  16. ncbi Presence of surfactant lamellar bodies in normal and diseased sinus mucosa
    Bradford A Woodworth
    Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    ORL J Otorhinolaryngol Relat Spec 67:199-202. 2005
    ..In addition to the lung, lamellar bodies have been identified in many other cell types throughout the human body. However, no prior studies have identified lamellar bodies in human sinus mucosa...
  17. ncbi Chronic rhinosinusitis in congenital craniofacial malformations
    Bradford A Woodworth
    Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, Charleston, 29425, USA
    Int J Pediatr Otorhinolaryngol 70:247-52. 2006
    ..To review developmental abnormalities and iatrogenic alterations in sinus anatomy that may predispose patients with congenital craniofacial malformations to chronic rhinosinusitis...
  18. ncbi Modified endoscopic medial maxillectomy for chronic maxillary sinusitis
    Bradford A Woodworth
    Department of Otolaryngology Head and Neck Surgery, 135 Rutledge Avenue, Suite 1130, P O Box 250550, Medical University of South Carolina, Charleston, SC 29425, USA
    Am J Rhinol 20:317-9. 2006
    ..However, few reports discuss the efficacy of MEMM for treatment of inflammatory disease of the maxillary sinus. We evaluate the efficacy of MEMM in treating chronic maxillary sinusitis...
  19. ncbi Innate and adaptive mediators in cystic fibrosis and allergic fungal rhinosinusitis
    Margaret L Skinner
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Rhinol 21:538-41. 2007
    ..The purpose of this study is to show and quantify the presence of SP A, SP D, tumor necrosis factor (TNF) alpha, (a Th1 marker), and eotaxin (a Th2 marker) in normal and diseased sinus mucosa...
  20. ncbi Immunolocalization of surfactant protein A and D in sinonasal mucosa
    Bradford A Woodworth
    Department of Otolaryngology Head and Neck Surgery, Medical University of South, Charleston 29425, USA
    Am J Rhinol 20:461-5. 2006
    ..Our prior studies are the first to identify the presence of these proteins in the human sinonasal cavity. The objective of this study was to immunolocalize SP-A and SP-D in human sinonasal tissue...
  21. ncbi Surfactant protein A and D in human sinus mucosa: a preliminary report
    Bradford A Woodworth
    Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    ORL J Otorhinolaryngol Relat Spec 69:57-60. 2007
    ..The objective of this study was to test our hypothesis that SP-A and SP-D are present in the human sinus...
  22. ncbi Immunolocalization of dendritic cells and pattern recognition receptors in chronic rhinosinusitis
    Andrew M Rampey
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina and the Ralph H Johnson VA Medical Center, Charleston, South Carolina, USA
    Am J Rhinol 21:117-21. 2007
    ..TLR binding is known to activate DCs. Based on these observations, we sought to establish the presence, in sinonasal mucosa, of DC and the pattern recognition receptors (PRRs), CD14, TLR2, and TLR4...
  23. ncbi Alterations in eotaxin, monocyte chemoattractant protein-4, interleukin-5, and interleukin-13 after systemic steroid treatment for nasal polyps
    Bradford A Woodworth
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    Otolaryngol Head Neck Surg 131:585-9. 2004
    ..To determine alterations in Th2 chemokines eotaxin and monocyte chemoattractant protein-4 (MCP-4), and cytokines interleukin-5 (IL-5) and interleukin-13 (IL-13), in nasal polyps (NP) after steroid treatment...
  24. ncbi Evolutions in the management of congenital intranasal skull base defects
    Bradford A Woodworth
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, USA
    Arch Otolaryngol Head Neck Surg 130:1283-8. 2004
    ..Congenital skull base defects have traditionally been treated via an intracranial approach. Recent advances in endoscopic management have made minimally invasive extracranial approaches feasible, with less morbidity...
  25. ncbi Comparison of laser versus surface-touch registration for image-guided sinus surgery
    Bradford A Woodworth
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina Hospital, Charleston 29425, USA
    Am J Rhinol 19:623-6. 2005
    ..The laser registration technique has been used previously; however, a less expensive surface-touch registration technique recently has been developed. We compared the accuracy and speed of laser and surface-touch registration techniques...
  26. ncbi Endoscopic resection of sinonasal hemangiomas and hemangiopericytomas
    Rodney J Schlosser
    Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    ORL J Otorhinolaryngol Relat Spec 68:69-72. 2006
    ..There are limited case reports of endoscopic resection of benign vascular tumors, including hemangiomas, or those with low-grade malignant potential, such as hemangiopericytomas...
  27. ncbi The delta F508 mutation in cystic fibrosis and impact on sinus development
    Bradford A Woodworth
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Rhinol 21:122-7. 2007
    ..The purpose of this study was to determine whether the homozygous delta F508 mutation is associated with an increased incidence of sinus hypoplasia when compared with other mutations...