Research Topics
Genomes and Genes | A WoodsSummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
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Detail Information
Publications
Syndecan-4 binding to the high affinity heparin-binding domain of fibronectin drives focal adhesion formation in fibroblastsA Woods
Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama, 35294 0019, USA
Arch Biochem Biophys 374:66-72. 2000..We now report that the glycosaminoglycan chains of syndecan-4 bind recombinant HepII and it is incorporated into forming focal adhesions...
Syndecan-4 and focal adhesion functionA Woods
Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294 0019, USA
Curr Opin Cell Biol 13:578-83. 2001..This is consistent with recent in vitro data indicating a need for signaling via syndecan-4 for focal adhesion formation, and reports that overexpression of proteins that bind syndecan-4 can modify cell adhesion and migration...
Syndecans: synergistic activators of cell adhesionA Woods
Dept of Cell Biology, University of Alabama at Birmingham 35294 0019, USA
Trends Cell Biol 8:189-92. 1998....
Control of morphology, cytoskeleton and migration by syndecan-4R L Longley
Department of Cell Biology and Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, Birmingham, Alabama, USA
J Cell Sci 112:3421-31. 1999..The data suggest that syndecan-4 is a regulator of focal adhesion and stress fiber formation, and influences both morphology and migration...
Syndecan-4 and integrins: combinatorial signaling in cell adhesionJ R Couchman
Department of Cell Biology and Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, University Boulevard, Birmingham, AL 35294 0019, USA
J Cell Sci 112:3415-20. 1999....
Syndecans and cell adhesionJ R Couchman
Department of Cell Biology and Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, 35294, USA
Int Rev Cytol 207:113-50. 2001..This review will describe this family of proteoglycans in terms of their structures and functions and their signaling in conjunction with integrins, and indicate areas for future research...
Syndecan 4 heparan sulfate proteoglycan is a selectively enriched and widespread focal adhesion componentA Woods
Department of Cell Biology, University of Alabama at Birmingham 35294 0019
Mol Biol Cell 5:183-92. 1994..Thus, syndecan 4 represents a new transmembrane focal adhesion component, probably involved in their assembly...
Serine phosphorylation of syndecan-2 proteoglycan cytoplasmic domainE S Oh
Department of Cell Biology, and Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, 35294, USA
Arch Biochem Biophys 344:67-74. 1997..5 mol/mol phosphorylation. Concentration-dependent dimerization was not altered by phosphorylation. Phosphorylation is, therefore, dependent on the conformation of syndecan-2 cytoplasmic domain, but does not affect its oligomeric status...
Proteoglycan isolation and analysisA Woods
University of Alabama at Birmingham, Birmingham, Alabama, USA
Curr Protoc Cell Biol . 2001..This unit describes detailed methods for purification of matrix, cell surface, and cytoskeleton-linked proteoglycans. Methods for analysis of glycoaminoglycan size and type and of core protein species are described...
The distribution and regulation of integrin-linked kinase in normal and diabetic kidneysL Guo
Department of Cell Biology and The Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, Birmingham, Alabama, USA
Am J Pathol 159:1735-42. 2001..These results suggest that ILK is likely involved in mesangial matrix expansion in response to hyperglycemia in the pathogenesis of diabetic glomerulosclerosis...
