E S Woodle

Summary

Affiliation: University of Cincinnati
Country: USA

Publications

  1. ncbi A multicenter pilot study of early (4-day) steroid cessation in renal transplant recipients under simulect, tacrolimus and sirolimus
    E Steve Woodle
    Division of Transplantation, Department of Surgery, University of Cincinnati, School of Medicine, Cincinnati, OH, USA
    Am J Transplant 5:157-66. 2005
  2. ncbi Histocompatibility testing predicts acute rejection risk in early corticosteroid withdrawal regimens
    E S Woodle
    Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:809-11. 2005
  3. ncbi A prospective, randomized, multicenter, double-blind study of early corticosteroid cessation versus long-term maintenance of corticosteroid therapy with tacrolimus and mycophenolate mofetil in primary renal transplant recipients: one year report
    E S Woodle
    Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:804-8. 2005
  4. ncbi A prospective, randomized, double-blind, placebo-controlled multicenter trial comparing early (7 day) corticosteroid cessation versus long-term, low-dose corticosteroid therapy
    E Steve Woodle
    Division of Transplantation, Department of Surgery, University of Cincinnati, Cincinnati, OH 45267, USA
    Ann Surg 248:564-77. 2008
  5. ncbi Multivariate analysis of risk factors for acute rejection in early corticosteroid cessation regimens under modern immunosuppression
    E Steve Woodle
    Division of Transplantation, University of Cincinnati, Cincinnati, OH, USA
    Am J Transplant 5:2740-4. 2005
  6. ncbi Proteasome inhibitor therapy for antibody-mediated rejection
    E S Woodle
    Department of Surgery, University of Cincinnati, Cincinnati, OH, USA
    Pediatr Transplant 15:548-56. 2011
  7. ncbi Early corticosteroid withdrawal under modern immunosuppression in renal transplantation: multivariate analysis of risk factors for acute rejection
    E S Woodle
    Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:798-9. 2005
  8. ncbi Proteasome inhibitor treatment of antibody-mediated allograft rejection
    E Steve Woodle
    Division of Transplantation, Department of Surgery, Hoxworth Blood Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    Curr Opin Organ Transplant 16:434-8. 2011
  9. ncbi Influence of educational programs on perceived barriers toward living donor kidney exchange programs
    E S Woodle
    Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 95249, USA
    Transplant Proc 37:602-4. 2005
  10. ncbi A prospective, randomized, multicenter study evaluating early corticosteroid withdrawal with Thymoglobulin in living-donor kidney transplantation
    E Steve Woodle
    Division of Transplantation, Department of Surgery, University of Cincinnati, Cincinnati, OH, USA
    Clin Transplant 24:73-83. 2010

Collaborators

Detail Information

Publications96

  1. ncbi A multicenter pilot study of early (4-day) steroid cessation in renal transplant recipients under simulect, tacrolimus and sirolimus
    E Steve Woodle
    Division of Transplantation, Department of Surgery, University of Cincinnati, School of Medicine, Cincinnati, OH, USA
    Am J Transplant 5:157-66. 2005
    ....
  2. ncbi Histocompatibility testing predicts acute rejection risk in early corticosteroid withdrawal regimens
    E S Woodle
    Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:809-11. 2005
    ..HLA matching, serologic PRA testing, and flow cytometry-based B cell crossmatching can all be used to predict acute rejection risk...
  3. ncbi A prospective, randomized, multicenter, double-blind study of early corticosteroid cessation versus long-term maintenance of corticosteroid therapy with tacrolimus and mycophenolate mofetil in primary renal transplant recipients: one year report
    E S Woodle
    Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:804-8. 2005
    ..0%), and improved CHD risk profile at 1 year posttransplantation...
  4. ncbi A prospective, randomized, double-blind, placebo-controlled multicenter trial comparing early (7 day) corticosteroid cessation versus long-term, low-dose corticosteroid therapy
    E Steve Woodle
    Division of Transplantation, Department of Surgery, University of Cincinnati, Cincinnati, OH 45267, USA
    Ann Surg 248:564-77. 2008
    ..To compare outcomes with early corticosteroid withdrawal (CSWD) and chronic low dose corticosteroid therapy (CCS)...
  5. ncbi Multivariate analysis of risk factors for acute rejection in early corticosteroid cessation regimens under modern immunosuppression
    E Steve Woodle
    Division of Transplantation, University of Cincinnati, Cincinnati, OH, USA
    Am J Transplant 5:2740-4. 2005
    ....
  6. ncbi Proteasome inhibitor therapy for antibody-mediated rejection
    E S Woodle
    Department of Surgery, University of Cincinnati, Cincinnati, OH, USA
    Pediatr Transplant 15:548-56. 2011
    ..These results demonstrate the significant potential of proteasome inhibition in addressing humoral barriers. However, the major advantage of proteasome inhibition lies in the numerous potential strategies for achieving synergy...
  7. ncbi Early corticosteroid withdrawal under modern immunosuppression in renal transplantation: multivariate analysis of risk factors for acute rejection
    E S Woodle
    Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:798-9. 2005
    ..These data strongly support the use of T-cell depleting antibody induction therapy in high-risk patients undergoing early withdrawal under modern immunosuppression...
  8. ncbi Proteasome inhibitor treatment of antibody-mediated allograft rejection
    E Steve Woodle
    Division of Transplantation, Department of Surgery, Hoxworth Blood Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    Curr Opin Organ Transplant 16:434-8. 2011
    ..The purpose of this review is to provide an update of recent basic science and clinical results with bortezomib in treating antibody-mediated rejection (AMR) that occurs in solid organ transplant recipients...
  9. ncbi Influence of educational programs on perceived barriers toward living donor kidney exchange programs
    E S Woodle
    Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 95249, USA
    Transplant Proc 37:602-4. 2005
    ..The aim of this study was to examine the effect of an educational conference on perceived barriers toward living donor kidney transplantation and LDKEPs...
  10. ncbi A prospective, randomized, multicenter study evaluating early corticosteroid withdrawal with Thymoglobulin in living-donor kidney transplantation
    E Steve Woodle
    Division of Transplantation, Department of Surgery, University of Cincinnati, Cincinnati, OH, USA
    Clin Transplant 24:73-83. 2010
    ....
  11. ncbi Ethical considerations for participation of nondirected living donors in kidney exchange programs
    E S Woodle
    The Paired Donation Network, Orlando, FL, USA
    Am J Transplant 10:1460-7. 2010
    ..Recent occurrences of BDs backing out argue for adoption of ethically based protective measures for NDD participation in KE...
  12. ncbi A prospective, pilot study of early corticosteroid cessation in high-immunologic-risk patients: the Cincinnati experience
    R R Alloway
    Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:802-3. 2005
    ..High-immunologic-risk patients may be able to undergo early CSWD with acceptable rates of acute rejection...
  13. ncbi Pilot study of early corticosteroid elimination after pancreas transplantation
    M J Hanaway
    University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:1287-8. 2005
    ..CONCLUSIONS: These results indicate that relatively short thymoglobulin induction (five doses) with tacrolimus and mycophenolate mofetil can allow early withdrawal in both pancreas-kidney and pancreas-only transplant recipients...
  14. ncbi Proteasome inhibition reduces donor-specific antibody levels
    M J Everly
    University of Cincinnati College of Medicine, and The Christ Hospital, Cincinnati, OH 45267 0558, USA
    Transplant Proc 41:105-7. 2009
    ..Bortezomib is approved by the US Food and Drug Administration for the treatment of plasma cell tumors (multiple myeloma)...
  15. ncbi Chemotherapy for posttransplant lymphoproliferative disorder: the Israel Penn International Transplant Tumor Registry experience
    J F Buell
    University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:956-7. 2005
    ..PTLD-specific death rates were 34%, 34%, 40%, and 48%. CONCLUSIONS: Single-agent chemotherapy appears to be inferior to other chemotherapy regimens for PTLD as it is associated with lower survival...
  16. ncbi Global cardiovascular risk under early corticosteroid cessation decreases progressively in the first year following renal transplantation
    C C Rogers
    Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:812-3. 2005
    ..This experience indicates that global cardiovascular risk decreases by approximately 10% at 1 year posttransplant in renal transplant recipients who undergo early corticosteroid withdrawal (CSWD)...
  17. ncbi Outcomes of patients with rejection post-polyomavirus nephropathy
    J Trofe
    Department of Surgery, Division of Transplantation, University of Cincinnati, Cincinnati, Ohio, USA
    Transplant Proc 37:942-4. 2005
    ..We sought to determine the effects of rejection in renal transplant recipients with polyomavirus nephropathy (PVN)...
  18. ncbi Prostate cancer prior to solid organ transplantation: the Israel Penn International Transplant Tumor Registry experience
    E S Woodle
    University of Cincinnati, Cincinnati, Ohio, USA
    Transplant Proc 37:958-9. 2005
    ..PCA recurrence rates are relatively low in patients who initially presented with stage I and II disease, and are half that of patients with stage III disease...
  19. ncbi Corticosteroid avoidance ameliorates lymphocele formation and wound healing complications associated with sirolimus therapy
    C C Rogers
    Department of Surgery, Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 45267-0558, USA
    Transplant Proc 37:795-7. 2005
    ..018) to develop a lymphocele. CONCLUSIONS: CSAV in a RAPA-based regimen results in a marked reduction in WHC and lymphoceles. Therefore, CSAV provides a promising approach for addressing WHC associated with RAPA therapy...
  20. ncbi De novo sarcomas in solid organ transplant recipients
    T L Husted
    Israel Penn International Transplant Tumor Registry, Division of Transplantation, The University of Cincinnati Medical School, 231 Albert Sabin Way, Cincinnati, OH 45267-0558, USA
    Transplant Proc 34:1786-7. 2002
  21. ncbi Reducing de novo donor-specific antibody levels during acute rejection diminishes renal allograft loss
    M J Everly
    Department of Surgery, Transplantation Division, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Am J Transplant 9:1063-71. 2009
    ..039). De novo DSAs detected at rejection are associated with reduced allograft survival, but prompt DSA reduction was associated with improved allograft survival. DSA should be considered a potential new end point for rejection therapy...
  22. ncbi Transplantation without steroids
    J W Alexander
    Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Transplant Proc 34:2076-8. 2002
  23. ncbi Central nervous system tumors in donors: misdiagnosis carries a high morbidity and mortality
    J F Buell
    University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:583-4. 2005
    ..Potential donors with unclear etiologies for brain death, particularly ICH, should be considered for a limited brain autopsy after donation...
  24. ncbi Early steroid withdrawal does not increase risk for recurrent focal segmental glomerulosclerosis
    R Boardman
    University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:817-8. 2005
    ..CONCLUSION: CSWD does not increase risk for recurrence of FSGS. These observations indicate that ECSW can be achieved in FSGS patients, thereby affording them the benefits of steroid elimination...
  25. ncbi Transmission of donor cancer into cardiothoracic transplant recipients
    J F Buell
    Israel Penn International Transplant Tumor Registry, Department of Surgery, University of Cincinnati, Ohio 45267, USA
    Surgery 130:660-6; discussion 666-8. 2001
    ....
  26. ncbi Simultaneous corticosteroid avoidance and calcineurin inhibitor minimization in renal transplantation
    J Wesley Alexander
    Department of Surgery, Transplantation Division, University of Cincinnati College of Medicine, OH 45267, USA
    Transpl Int 19:295-302. 2006
    ..Fifty-seven percent of 54 patients with a functioning kidney at 3 years were receiving monotherapy with RAPA. We conclude that this therapeutic strategy is worthy of a prospective multi-center clinical trial...
  27. ncbi Polyomavirus in kidney and kidney-pancreas transplantation: a defined protocol for immunosuppression reduction and histologic monitoring
    Jennifer Trofe
    Department of Surgery, Division of Transplantation, The University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267-0558, USA
    Transplant Proc 34:1788-9. 2002
  28. ncbi OKT3 escalating dose regimens provide effective therapy for renal allograft rejection
    E S Woodle
    Department of Surgery, University of Chicago, Illinois 60637, USA
    Clin Transplant 10:389-95. 1996
    ....
  29. ncbi Skin cancer following transplantation: the Israel Penn International Transplant Tumor Registry experience
    J F Buell
    Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:962-3. 2005
    ..6%) group. CONCLUSIONS: This large experience indicates that SCC is more common than BCC in transplant recipients. SCC alone or in combination with BCC appears aggressive and is associated with significant mortality...
  30. ncbi De novo colorectal cancer: five-year survival is markedly lower in transplant recipients compared with the general population
    J F Buell
    Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:960-1. 2005
    ..These data cannot distinguish whether the lower survival rates are because the CRC are inherently biologically more aggressive or whether immunosuppression allows for more aggressive clinical behavior of CRC...
  31. ncbi Laparoscopic right living donor nephrectomy
    T L Husted
    University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:631-2. 2005
    ..This observation increases the options for LDN in patients with multiple left renal arteries, or with right renal cysts, or with right kidneys that are smaller in size compared to the contralateral left kidney...
  32. ncbi Posttransplant lymphoproliferative disorder: significance of central nervous system involvement
    J F Buell
    Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:954-5. 2005
    ..Radiation therapy alone provides the best results, but this may be a reflection of isolated CNS disease...
  33. ncbi Donor kidneys with small renal cell cancers: can they be transplanted?
    J F Buell
    University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:581-2. 2005
    ..The purpose of this study was to determine whether incidentally discovered, small renal cell cancers (RCC) in donor kidneys can be excised and safely transplanted...
  34. ncbi Immunosuppression with belatacept-based, corticosteroid-avoiding regimens in de novo kidney transplant recipients
    R Ferguson
    Ohio State University College of Medicine, Columbus, OH, USA
    Am J Transplant 11:66-76. 2011
    ....
  35. ncbi Immunosuppression and Merkel cell cancer
    Joseph F Buell
    Israel Penn International Transplant Tumor Registry, Division of Transplantation, The University of Cincinnati Medical School, 231 Albert Sabin Way, Cincinnati, OH 45267-0558, USA
    Transplant Proc 34:1780-1. 2002
  36. ncbi Body weight alterations under early corticosteroid withdrawal and chronic corticosteroid therapy with modern immunosuppression
    C C Rogers
    University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:800-1. 2005
    ..Caucasians and overweight patients demonstrate greater benefits from CSWD than African Americans and patients with normal BMI...
  37. ncbi Proteasome inhibitor-based primary therapy for antibody-mediated renal allograft rejection
    R Carlin Walsh
    Department of Surgery, Division of Transplantation, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Transplantation 89:277-84. 2010
    ..Our initial experience with proteasome inhibition as a first-line therapy for AMR is presented...
  38. ncbi Body weight alterations under early corticosteroid withdrawal and chronic corticosteroid therapy with modern immunosuppression
    Christin C Rogers
    Department of Surgery, Division of Transplantation, University of Cincinnati, Cincinnati, OH 45267-0558, USA
    Transplantation 80:26-33. 2005
    ..CONCLUSIONS: Early CSWD minimizes weight gain in renal-transplant recipients. Women, whites, and patients with high pretransplant BMI had greater reductions in weight gain with early CSWD...
  39. ncbi Liver transplantation for primary or metastatic sarcoma to the liver
    T L Husted
    The Israel Penn International Transplant Tumor Registry, University of Cincinnati, Cincinnati, Ohio
    Am J Transplant 6:392-7. 2006
    ....
  40. ncbi Kidney exchange programs: attitudes of transplant team members toward living donation and kidney exchanges
    E S Woodle
    Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 95249, USA
    Transplant Proc 37:600-1. 2005
    ..However, they remain indecisive about LDKEP participation. These results indicate that barriers exist in the transplant community toward LDKEP, and these must be defined to increase LDKEP acceptance and participation...
  41. ncbi Laparoscopic live donor nephrectomy: rationale, techniques, and implications
    S R Potter
    Department of Surgery, Division of Transplantation, University of Cincinnati, Cincinnati, Ohio, USA
    Semin Dial 14:365-72. 2001
    ..We review the development and refinement of LDN and its current rationale and applications...
  42. ncbi Methicillin-resistant Staphylococcus aureus infection in liver transplantation: a matched controlled study
    C R Schneider
    Division of Transplantation University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:1243-4. 2005
    ..6). CONCLUSION: MRSA infection is associated with a higher incidence of posttransplant complications and antibiotic usage in both liver and kidney recipients compared to patients with MRSA infection...
  43. ncbi Liver transplantation in the first three months of life
    E S Woodle
    Department of Surgery, University of Chicago, Illinois 60637, USA
    Transplantation 66:606-9. 1998
    ..Although infants in the first 3 months of life have not traditionally been considered a distinct age group, several features of these infants may distinguish them from other pediatric liver transplant recipients...
  44. ncbi A prospective trial of a steroid-free/calcineurin inhibitor minimization regimen in human leukocyte antigen (HLA)-identical live donor renal transplantation
    Jennifer K Walker
    Department of Surgery, Division of Transplantation, University of Cincinnati, Cincinnati, OH 45267 0585, USA
    Transplantation 87:408-14. 2009
    ..This prospective study evaluated a corticosteroid (CS)-free, calcineurin inhibitor (CNI) minimization immunosuppressive regimen in HLA-identical LD renal transplant recipients...
  45. ncbi Polyomavirus nephropathy in kidney transplantation
    Jennifer Trofe
    University of Cincinnati, Division of Transplantation, Ohio, USA
    Prog Transplant 14:130-40; quiz 141-2. 2004
    ..This review presents potential risk factors, screening, diagnostic and monitoring methods, therapeutic management, and retransplantation experience for polyomavirus nephropathy...
  46. ncbi Gastric cancer in transplant recipients: detection of malignancy [correction of malignacy] by aggressive endoscopy
    Joseph F Buell
    Israel Penn International Transplant Tumor Registry, Division of Transplantation, The University of Cincinnati Medical School, 231 Albert Sabin Way, Cincinnati, OH 45267-0558, USA
    Transplant Proc 34:1784-5. 2002
  47. ncbi Laparoscopic living donor nephrectomy for kidneys with multiple arteries
    T L Husted
    University of Cincinnati, Cincinnati, Ohio 45249, USA
    Transplant Proc 37:629-30. 2005
    ..7 +/- 1.47) and at postoperative day 365 (1.06 +/- 0.3 and 1.34 +/- 0.44). CONCLUSIONS: This experience confirms results from other series in documenting the safety and reproducibility of LDN for kidneys with multiple arterial vessels...
  48. ncbi Are concerns over right laparoscopic donor nephrectomy unwarranted?
    J F Buell
    Department of Surgery, University of Cincinnati, Cincinnati, Ohio, USA
    Ann Surg 233:645-51. 2001
    ..To examine the ability of several large, experienced transplantation centers to perform right-sided laparoscopic donor nephrectomy safely with equivalent long-term renal allograft function...
  49. ncbi Phase I trial of a humanized, Fc receptor nonbinding OKT3 antibody, huOKT3gamma1(Ala-Ala) in the treatment of acute renal allograft rejection
    E S Woodle
    Department of Surgery, Committee on Immunology, Ben May Institute for Cancer Research, University of Chicago, Illinois 60637, USA
    Transplantation 68:608-16. 1999
    ..This report describes the results of a phase I trial of huOKT3gamma1(Ala-Ala) treatment of acute renal allograft rejection...
  50. ncbi De novo breast cancer in renal transplant recipients
    Joseph F Buell
    Israel Penn International Transplant Tumor Registry, Division of Transplantation, The University of Cincinnati Medical School, 231 Albert Sabin Way, Cincinnati, OH 45267-0558, USA
    Transplant Proc 34:1778-9. 2002
  51. ncbi African-American renal transplant recipients benefit from early corticosteroid withdrawal under modern immunosuppression
    Robyn E Boardman
    Department of Surgery, Division of Transplantation, University of Cincinnati, Cincinnati, OH, USA
    Am J Transplant 5:356-65. 2005
    ..Additional follow-up is needed to determine long-term renal function, graft survival, and cardiovascular risk in AAs with early CSWD...
  52. ncbi Posttransplant malignancy
    Jennifer Trofe
    Israel Penn International Transplant Tumor Registry, University of Cincinnati, Cincinnati, Ohio, USA
    Prog Transplant 14:193-200. 2004
    ..This review presents the more commonly encountered posttransplant malignancies and the measures that are currently being utilized to prevent and treat them...
  53. ncbi Bortezomib provides effective therapy for antibody- and cell-mediated acute rejection
    Matthew J Everly
    Department of Surgery, Division of Transplantation, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0558, USA
    Transplantation 86:1754-61. 2008
    ..We report the first clinical experience with plasma cell-targeted therapy (bortezomib) as an antirejection strategy...
  54. ncbi Safety, efficacy, and cost analysis of thymoglobulin induction therapy with intermittent dosing based on CD3+ lymphocyte counts in kidney and kidney-pancreas transplant recipients
    V Ram Peddi
    University of Cincinnati Medical Center, Cincinnati, Ohio 45267 0585, USA
    Transplantation 73:1514-8. 2002
    ..In view of the superior T-cell depletion and prolonged half-life of thymoglobulin, we initiated a protocol to administer thymoglobulin intermittently based on peripheral blood CD3+ lymphocyte counts...
  55. ncbi Basic and clinical research in polyomavirus nephropathy
    Jennifer Trofe
    Division of Transplantation, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267 0558, USA
    Exp Clin Transplant 2:162-73. 2004
    ..This review will present recent advances in basic and clinical research related to PVN and renal transplantation...
  56. ncbi Malignancy after transplantation
    Joseph F Buell
    Israel Penn International Transplant Tumor Registry, University of Cincinnati, Cincinnati, OH 45267 0558, USA
    Transplantation 80:S254-64. 2005
    ..Long-term data are needed to determine if the use of these agents will ultimately lower the mortality due to malignancy for transplant recipients...
  57. ncbi Donors with central nervous system malignancies: are they truly safe?
    Joseph F Buell
    Department of Surgery, The Israel Penn International Transplant Tumor Registry, The University of Cincinnati School of Medicine, OH 45267 0558, USA
    Transplantation 76:340-3. 2003
    ..One strategy is the use of organs from patients with a history of or active central nervous system (CNS) tumor...
  58. ncbi Can immunonutrients reduce rejection rates in African Americans?
    J Wesley Alexander
    Department of Surgery, Department of Internal Medicine, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0585, USA
    Exp Clin Transplant 3:349-50. 2005
    ..African-American kidney allograft recipients have higher rates of rejection than do white patients. This study was performed to determine whether the use of immunonutrients may reduce the incidence of rejection in African Americans...
  59. ncbi Malignancy in pediatric transplant recipients
    Joseph F Buell
    The Israel Penn International Transplant Tumor Registry, Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 45267, USA
    Semin Pediatr Surg 15:179-87. 2006
    ..This leaves transplant physicians with several new and novel immunosuppressive agents with uncertain oncologic potentials that will need to be examined over the next decade...
  60. ncbi Cardiovascular risk, cardiovascular events, and metabolic syndrome in renal transplantation: comparison of early steroid withdrawal and chronic steroids
    Adele H Rike
    Division of Transplantation, Department of Surgery, University of Cincinnati, Cincinnati, OH 45219, USA
    Clin Transplant 22:229-35. 2008
    ..The purpose of this study was to compare Framingham Risk Score (FRS), metabolic syndrome (MS), and cardiovascular events (CVE) in patients receiving early corticosteroid withdrawal (ECSWD), or chronic corticosteroid therapy (CCS)...
  61. ncbi Influence of long chain polyunsaturated fatty acids and ornithine concentrations on complications after renal transplant
    J Wesley Alexander
    Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Exp Clin Transplant 6:118-26. 2008
    ....
  62. ncbi Recurrence risk after organ transplantation in patients with a history of Hodgkin disease or non-Hodgkin lymphoma
    Jennifer Trofe
    Israel Penn International Transplant Tumor Registry, Division of Transplantation, University of Cincinnati, Cincinnati, Ohio 45267 0558, USA
    Transplantation 78:972-7. 2004
    ..There is no difference in recurrence rates for HD and NHL. The outcome for recurrent lymphoma is poor. The low risk of recurrence (10%) indicates that preexisting HD and NHL need not be an absolute contraindication to transplantation...
  63. ncbi Hand-assisted laparoscopic living-donor nephrectomy as an alternative to traditional laparoscopic living-donor nephrectomy
    Joseph F Buell
    Division of Transplantation, The University of Cincinnati, Cincinnati, Ohio 45267, USA
    Am J Transplant 2:983-8. 2002
    ..Thus, similar to traditional laparoscopic donor nephrectomy, hand-assisted laparoscopic living-donor nephrectomy provides advantages over open donor nephrectomy without increasing costs...
  64. ncbi Maximizing renal artery length in right laparoscopic donor nephrectomy by retrocaval exposure of the aortorenal junction
    Joseph F Buell
    Division of Transplant Surgery, Department of Surgery, The University of Cincinnati, Cincinnati, OH 45267 0558, USA
    Transplantation 75:83-5. 2003
    ..This technique has currently been used in 20 consecutive right LDN operations without vascular complications or technical graft losses...
  65. ncbi Analysis of factors that influence survival with post-transplant lymphoproliferative disorder in renal transplant recipients: the Israel Penn International Transplant Tumor Registry experience
    Jennifer Trofe
    Israel Penn International Transplant Tumor Registry, Division of Transplantation, University of Cincinnati, Cincinnati, OH, USA
    Am J Transplant 5:775-80. 2005
    ..0001). Death risk was greater for multiple site PTLD and increasing age, and risks were additive. Univariate analysis identified increased death risk for those not receiving surgery, particularly allograft involvement alone...
  66. ncbi The influence of immunomodulatory diets on transplant success and complications
    J Wesley Alexander
    Department of Surgery, Division of Transplantation, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0558, USA
    Transplantation 79:460-5. 2005
    ..They also reduce cardiovascular complications and infections in humans...
  67. ncbi Gastric bypass in morbidly obese patients with chronic renal failure and kidney transplant
    J Wesley Alexander
    UC Surgeons, Inc Center for Surgical Weight Loss, University of Cincinnati, Cincinnati, OH 45267 0558, USA
    Transplantation 78:469-74. 2004
    ..Morbid obesity is also associated with an increased risk of complications and death in transplant patients and is often a cause for denial for access to transplantation...
  68. ncbi Characteristics and survival patterns of solid organ transplant patients developing de novo colon and rectal cancer
    Harry T Papaconstantinou
    Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9156, USA
    Dis Colon Rectum 47:1898-903. 2004
    ..The purpose of this study was to define the characteristics and survival patterns of transplant patients developing de novo colorectal cancer...
  69. ncbi Kidney transplantation: graft monitoring and immunosuppression
    Jonathan S Fisher
    Section of Transplantation, Department of Surgery, University of Tennessee, Room A-202, Memphis, Tennessee 38103, USA
    World J Surg 26:185-93. 2002
    ..Hopefully, these assays will serve as a guide for the reduction and possible removal of immunosuppressive agents from stable renal allograft recipients...
  70. ncbi Surgical techniques in right laparoscopic donor nephrectomy
    Joseph F Buell
    Department of Surgery, University of Cincinnati College of Medicine, OH 45267-0558, USA
    J Am Coll Surg 195:131-7. 2002
  71. ncbi Right donor nephrectomy: a comparison of hand-assisted transperitoneal and retroperitoneal laparoscopic approaches
    Joseph F Buell
    The University of Cincinnati, Cincinnati, OH, USA
    Transplantation 77:521-5. 2004
    ..No grafts were lost in either group. CONCLUSIONS: This study confirms that the HALDN and RLDN techniques can provide kidney grafts with equivalent-length vessels and excellent function...
  72. ncbi Incidental diagnosis of gastric cancer in transplant recipients improves patient survival
    Joseph F Buell
    Israel Penn International Transplant Registry, The University of Cincinnati, Cincinnati, Ohio 45267-0558, USA
    Surgery 132:754-8; discussion 758-60. 2002
    ..Early detection has resulted in a 29% 5-year survival for the entire transplant recipient group compared with a 5% to 15% 5-year survival in the general population...
  73. ncbi Corticosteroid elimination in renal transplantation: pro
    E S Woodle
    Department of Surgery, Division of Transplantation, University of Cincinnati, 231 Bethesday Avenue, PO Box 670558, Cincinnati, OH 45267, USA
    Transplant Proc 34:1693. 2002
  74. ncbi De novo cancers arising in organ transplant recipients are associated with adverse outcomes compared with the general population
    Yun Miao
    Division of Transplantation, Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0558, USA
    Transplantation 87:1347-59. 2009
    ..The purpose of this study was to examine the influence of transplantation on the outcomes of individual cancers...
  75. ncbi Proteasome inhibition for antibody-mediated rejection
    Jason J Everly
    Department of Surgery, University of Cincinnati College of Medicine, Ohio, USA
    Curr Opin Organ Transplant 14:662-6. 2009
    ..The purpose of this review is to describe the biochemistry and physiology of proteasome inhibition and to discuss recent studies with proteasome inhibitor therapy in organ transplantation...
  76. ncbi Laparoscopic donor nephrectomy vs. open live donor nephrectomy: a quality of life and functional study
    Joseph F Buell
    The University Hospital, Cincinnati, OH 45267-0004, USA
    Clin Transplant 19:102-9. 2005
    ..2; p = 0.19). The overall QoL for both groups was comparable with the general USA population. CONCLUSIONS: The results of this study support the decisions of many kidney transplant centers to adopt LDN programs as standard of care...
  77. ncbi Composite tissue allotransplantation: a review of relevant immunological issues for plastic surgeons
    Iain S Whitaker
    Department of Surgery, University of Louisville, 511 South Floyd Street, 320 MDR Building, Louisville, KY 40202, USA
    J Plast Reconstr Aesthet Surg 61:481-92. 2008
    ..With this in mind, the purpose of this manuscript is to provide plastic surgeons with a comprehensive and understandable review of key immunological principles relevant to composite tissue allotransplantation...
  78. ncbi Risk assessment of immunosuppressive therapy in facial transplantation
    Dalibor Vasilic
    Department of Surgery, University of Louisville, Louisville, KY 40202, USA
    Plast Reconstr Surg 120:657-68. 2007
    ..This review provides a comprehensive risk assessment for facial transplantation based on comparable data of immunosuppression, recipient health status, and composition and antigenicity of the transplanted tissue...
  79. ncbi The role of immunosuppression in lymphoma
    Jennifer Trofe
    Department of Surgery, University of Cincinnati, OH 45267-0558, USA
    Recent Results Cancer Res 159:55-66. 2002
    ..We review the major historical and recent immunosuppression trials to assess the impact of individual immunosuppressive agents and regimens on PTLD risk...
  80. ncbi A history of living donor transplantation: from twins to trades
    E S Woodle
    Division of Transplantation, Department of Surgery, University of Cincinnati, 231 Albert Sabin Way, PO Box 670558, Cincinnati, OH 45267, USA
    Transplant Proc 35:901-2. 2003
  81. ncbi Programmed cell death
    E S Woodle
    Department of Surgery, University of Chicago, Illinois 60637, USA
    Transplantation 66:681-91. 1998
    ..This Overview provides a definition of PCD, a description of known PCD biochemical pathways, and finally a discussion of the implications of PCD in transplantation...
  82. ncbi Programmed cell death signaling via cell-surface expression of a single-chain antibody transgene
    S Kulkarni
    Department of Surgery, University of Chicago, Illinois 60637, USA
    Transplantation 69:1209-17. 2000
    ..Immobilized 5H7 delivers programmed cell death (PCD) signals to human lymphoid tumor cells as well as peripheral blood mononuclear cells...
  83. ncbi West Nile virus encephalitis in organ transplant recipients: another high-risk group for meningoencephalitis and death
    Debby DeSalvo
    Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0585, USA
    Transplantation 77:466-9. 2004
    ..Suggestions for the prevention, diagnosis, and treatment of West Nile virus infection in this patient population are described...
  84. ncbi MALToma: a Helicobacter pylori-associated malignancy in transplant patients: a report from the Israel Penn International Transplant Tumor Registry with a review of published literature
    Meredith J Aull
    Division of Nephrology and Hypertension, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH 45267, USA
    Transplantation 75:225-8. 2003
    ..Observation of malignant degeneration into an aggressive, high-grade lymphoma in one patient indicates the malignant potential. Diligent follow-up of these patients with endoscopy and biopsy is therefore indicated...
  85. ncbi Laparoscopic liver resection
    Joseph F Buell
    Division of Transplantation, The University of Cincinnati, Cincinnati, OH 45267-0558, USA
    J Am Coll Surg 200:472-80. 2005
  86. ncbi An initial experience and evolution of laparoscopic hepatic resectional surgery
    Joseph F Buell
    Division of Transplantation, University of Cincinnati, OH 45267-0558, USA
    Surgery 136:804-11. 2004
    ..Minimally invasive surgery appears to provide several distinct advantages over traditional open hepatic surgery. However, techniques for the laparoscopic control of bleeding and bile leak remain in their infancy...
  87. ncbi Liver transplantation for primary and metastatic hepatic malignancy: a single center experience
    Amit D Tevar
    Division of Transplantation, Department of Surgery, University of Cincinnati, Ohio 45267-0558, USA
    Surgery 139:535-41. 2006
  88. ncbi The potential of paired donation programs: modeling and reality
    E Steve Woodle
    Am J Transplant 5:1787-8. 2005
  89. ncbi Successful retransplantation after renal allograft loss to polyoma virus interstitial nephritis
    Rajiv D Poduval
    Division of Nephrology, Department of Medicine, University of Chicago, Chicago, IL 60637, USA
    Transplantation 73:1166-9. 2002
    ..Previous graft loss secondary to polyoma virus infection is not a contraindication to retransplantation...
  90. ncbi Monitoring of inosine monophosphate dehydrogenase activity as a biomarker for mycophenolic acid effect: potential clinical implications
    Nicole A Weimert
    Department of Pharmacy Services, Medical University of South Carolina, Charleston, South Carolina, USA
    Ther Drug Monit 29:141-9. 2007
    ..Quantification of IMPDH posttransplant may serve as a stable, surrogate PD marker of MPA-induced immunosuppression when combined with current PK and monitoring strategies...
  91. ncbi A comparison of tacrolimus and cyclosporine in liver transplantation: effects on renal function and cardiovascular risk status
    Michael R Lucey
    University of Wisconsin Medical School, Madison, WI, USA
    Am J Transplant 5:1111-9. 2005
    ..While both calcineurin inhibitors were associated with excellent patient and graft survival, renal function, blood pressure and serum lipid levels were significantly better with tacrolimus treatment...
  92. ncbi Interplay of cellular and humoral immune responses against BK virus in kidney transplant recipients with polyomavirus nephropathy
    YiPing Chen
    Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    J Virol 80:3495-505. 2006
    ..A high degree of epitope cross-recognition was present between BKV and corresponding JCV-specific CTLs, which indicates that the same population of cells is functionally effective against these two closely related viruses...
  93. ncbi BKV and JCV large T antigen-specific CD8+ T cell response in HLA A*0201+ kidney transplant recipients with polyomavirus nephropathy and patients with progressive multifocal leukoencephalopathy
    YiPing Chen
    Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    J Clin Virol 42:198-202. 2008
    ..The large T-antigen (T-ag) is the main regulatory protein of polyomaviruses that is expressed early in the viral cycle...
  94. ncbi Transplant recipient's knowledge of posttransplant malignancy risk: implications for educational programs
    H Myron Kauffman
    Organ Procurement and Transplantation Network, United Network for Organ Sharing, Richmond, VA, USA
    Transplantation 85:928-33. 2008
  95. ncbi United network for organ sharing publication on scientific registry of transplant recipients central nervous system donor cancer transmission data
    Joseph F Buell
    Transplantation 79:623. 2005
  96. ncbi Experience with 274 cardiac transplant recipients with posttransplant lymphoproliferative disorder: a report from the Israel Penn International Transplant Tumor Registry
    Meredith J Aull
    Department of Pharmacy, New York Presbyterian Hospital-New York Weill Cornell Center, New York, NY, USA
    Transplantation 78:1676-82. 2004
    ..Carefully designed prospective studies are needed to evaluate the positive and negative effects of ISM in cardiac transplant recipients with PTLD...