Stephen P Wooding

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. pmc Association of a bitter taste receptor mutation with Balkan Endemic Nephropathy (BEN)
    Stephen P Wooding
    McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX 75244, USA
    BMC Med Genet 13:96. 2012
  2. doi request reprint Signatures of natural selection in a primate bitter taste receptor
    Stephen Wooding
    McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX 75390 8591, USA
    J Mol Evol 73:257-65. 2011
  3. doi request reprint Genetics and bitter taste responses to goitrin, a plant toxin found in vegetables
    Stephen Wooding
    McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, TX 75390 8591, USA
    Chem Senses 35:685-92. 2010
  4. doi request reprint Genetic, functional, and phenotypic diversity in TAS2R38-mediated bitter taste perception
    Maik Behrens
    Department of Molecular Genetics, German Institute of Human Nutrition Potsdam Rehbruecke, Arthur Scheunert Allee 114 116, Nuthetal 14558, Germany
    Chem Senses 38:475-84. 2013

Research Grants

  1. Evolutionary Dissection of complex traits
    Stephen Wooding; Fiscal Year: 2007

Collaborators

Detail Information

Publications4

  1. pmc Association of a bitter taste receptor mutation with Balkan Endemic Nephropathy (BEN)
    Stephen P Wooding
    McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX 75244, USA
    BMC Med Genet 13:96. 2012
    ..This suggests that genetic variation in TAS2R43 might affect susceptibility to BEN, with individuals carrying functional forms of the receptor being protected by an ability to detect tainted foods...
  2. doi request reprint Signatures of natural selection in a primate bitter taste receptor
    Stephen Wooding
    McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX 75390 8591, USA
    J Mol Evol 73:257-65. 2011
    ..53) consistent with rapid shifts in ligand targeting. These patterns point to a history of rapid yet constrained change in bitter taste responses in the course of primate evolution...
  3. doi request reprint Genetics and bitter taste responses to goitrin, a plant toxin found in vegetables
    Stephen Wooding
    McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, TX 75390 8591, USA
    Chem Senses 35:685-92. 2010
    ..16) than for PROP (r(2) = 0.50) and PTC (r(2) = 0.57). These findings suggest that mutations in TAS2R38 play a role in shaping goitrin perception, but the majority of variance must be explained by other factors...
  4. doi request reprint Genetic, functional, and phenotypic diversity in TAS2R38-mediated bitter taste perception
    Maik Behrens
    Department of Molecular Genetics, German Institute of Human Nutrition Potsdam Rehbruecke, Arthur Scheunert Allee 114 116, Nuthetal 14558, Germany
    Chem Senses 38:475-84. 2013
    ..However, prior studies have indicated that these alleles are common in some global regions, suggesting that alleles rare in our sample may be phenotypically relevant in other populations...

Research Grants3

  1. Evolutionary Dissection of complex traits
    Stephen Wooding; Fiscal Year: 2007
    ..By applying a combined evolutionary and epidemiological approach, these analyses may shed new light on the relationship between genetic variation, environmental response, and human health. ..