W M Wood

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. ncbi request reprint An upstream regulator of the glycoprotein hormone alpha-subunit gene mediates pituitary cell type activation and repression by different mechanisms
    W M Wood
    Division of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Biol Chem 274:15526-32. 1999
  2. ncbi request reprint Structural and functional characterization of the genomic locus encoding the murine beta 2 thyroid hormone receptor
    W M Wood
    Department of Medicine, University of Colorado Health Sciences Center, Denver 80262
    Mol Endocrinol 8:1605-17. 1994
  3. ncbi request reprint Msx1 is present in thyrotropic cells and binds to a consensus site on the glycoprotein hormone alpha-subunit promoter
    V D Sarapura
    University of Colorado Health Sciences Center, Denver 80262, USA
    Mol Endocrinol 11:1782-94. 1997
  4. ncbi request reprint The effect of thyroid hormone and a long-acting somatostatin analogue on TtT-97 murine thyrotropic tumors
    W W Woodmansee
    Division of Endocrinology, University of Colorado Health Sciences Center, Denver 80262, USA
    Thyroid 10:533-41. 2000
  5. ncbi request reprint Pit-1 and GATA-2 interact and functionally cooperate to activate the thyrotropin beta-subunit promoter
    D F Gordon
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Biol Chem 272:24339-47. 1997
  6. ncbi request reprint Activation of the glycoprotein hormone alpha-subunit gene promoter in thyrotropes
    V D Sarapura
    Department of Medicine, University of Colorado Health Sciences Center, Denver 80262, USA
    Mol Cell Endocrinol 146:77-86. 1998
  7. ncbi request reprint Analysis of Pit-1 in regulating mouse TSH beta promoter activity in thyrotropes
    D F Gordon
    Department of Medicine, University of Colorado Health Sciences Center, Denver 80262
    Mol Cell Endocrinol 96:75-84. 1993
  8. ncbi request reprint Cloning of the mouse somatostatin receptor subtype 5 gene: promoter structure and function
    D F Gordon
    Division of Endocrinology, Metabolism, and Diabetes, University of Colorado Health Sciences Center, Denver 80262, USA
    Endocrinology 140:5598-608. 1999
  9. ncbi request reprint A thyrotrope-specific variant of Pit-1 transactivates the thyrotropin beta promoter
    B R Haugen
    Department of Medicine, University of Colorado Health Sciences Center, Denver 80262
    J Biol Chem 268:20818-24. 1993
  10. ncbi request reprint Reverse transcription polymerase chain reaction analysis of pituitary hormone, Pit-1 and steroidogenic factor-1 messenger RNA expression in pituitary tumors
    M T McDermott
    Division of Endocrinology, University of Colorado Health Sciences Center, Denver 80262, USA
    Pituitary 2:217-24. 1999

Collaborators

Detail Information

Publications20

  1. ncbi request reprint An upstream regulator of the glycoprotein hormone alpha-subunit gene mediates pituitary cell type activation and repression by different mechanisms
    W M Wood
    Division of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Biol Chem 274:15526-32. 1999
    ....
  2. ncbi request reprint Structural and functional characterization of the genomic locus encoding the murine beta 2 thyroid hormone receptor
    W M Wood
    Department of Medicine, University of Colorado Health Sciences Center, Denver 80262
    Mol Endocrinol 8:1605-17. 1994
    ..We therefore conclude that the promoter region responsible for expression of the TR beta 2 isoform in pituitary thyrotropes is distinct from that described for TR beta 1 and is located many kilobases upstream from their common exons...
  3. ncbi request reprint Msx1 is present in thyrotropic cells and binds to a consensus site on the glycoprotein hormone alpha-subunit promoter
    V D Sarapura
    University of Colorado Health Sciences Center, Denver 80262, USA
    Mol Endocrinol 11:1782-94. 1997
    ..These studies suggest that Msx1 may play a role in the expression of the alpha-subunit gene in thyrotrope cells...
  4. ncbi request reprint The effect of thyroid hormone and a long-acting somatostatin analogue on TtT-97 murine thyrotropic tumors
    W W Woodmansee
    Division of Endocrinology, University of Colorado Health Sciences Center, Denver 80262, USA
    Thyroid 10:533-41. 2000
    ..These data suggest an important interaction between the somatostatinergic system and thyroid hormone in the regulation of thyrotrope cell structure and function...
  5. ncbi request reprint Pit-1 and GATA-2 interact and functionally cooperate to activate the thyrotropin beta-subunit promoter
    D F Gordon
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Biol Chem 272:24339-47. 1997
    ..In summary, these data demonstrate functional synergy and physical interaction between homeobox and zinc finger factors and provide insights into the transcriptional mechanisms of thyrotrope-specific gene expression...
  6. ncbi request reprint Activation of the glycoprotein hormone alpha-subunit gene promoter in thyrotropes
    V D Sarapura
    Department of Medicine, University of Colorado Health Sciences Center, Denver 80262, USA
    Mol Cell Endocrinol 146:77-86. 1998
    ..This analysis provides basic information important to identify common and unique factors contributing to the cell-specific expression of the alpha-subunit gene...
  7. ncbi request reprint Analysis of Pit-1 in regulating mouse TSH beta promoter activity in thyrotropes
    D F Gordon
    Department of Medicine, University of Colorado Health Sciences Center, Denver 80262
    Mol Cell Endocrinol 96:75-84. 1993
    ..These studies suggest that Pit-1 is not limiting for cell-specific expression of the TSH beta gene in thyrotrope-derived cells and implies that additional thyrotropic factors are likely required...
  8. ncbi request reprint Cloning of the mouse somatostatin receptor subtype 5 gene: promoter structure and function
    D F Gordon
    Division of Endocrinology, Metabolism, and Diabetes, University of Colorado Health Sciences Center, Denver 80262, USA
    Endocrinology 140:5598-608. 1999
    ..Cloning of the sst5 gene will facilitate the mapping of basal and regulated responses at the transcriptional level...
  9. ncbi request reprint A thyrotrope-specific variant of Pit-1 transactivates the thyrotropin beta promoter
    B R Haugen
    Department of Medicine, University of Colorado Health Sciences Center, Denver 80262
    J Biol Chem 268:20818-24. 1993
    ..These data suggest that Pit-1T is a thyrotrope-specific splice variant of Pit-1 that is required for TSH beta promoter stimulation; furthermore, both Pit-1 and Pit-1T are required for TSH beta promoter activity in thyrotrope cells...
  10. ncbi request reprint Reverse transcription polymerase chain reaction analysis of pituitary hormone, Pit-1 and steroidogenic factor-1 messenger RNA expression in pituitary tumors
    M T McDermott
    Division of Endocrinology, University of Colorado Health Sciences Center, Denver 80262, USA
    Pituitary 2:217-24. 1999
    ..Combined analysis of hormone and transcription factor mRNA in pituitary tumor tissue may therefore be a more meaningful approach to pituitary tumor characterization...
  11. ncbi request reprint Organization and nucleotide sequence of the gene encoding the beta-subunit of murine thyrotropin
    D F Gordon
    Department of Medicine, University of Colorado Health Sciences Center, Denver 80262
    DNA 7:17-26. 1988
    ....
  12. ncbi request reprint Expression of the beta-subunit gene of murine thyrotropin results in multiple messenger ribonucleic acid species which are generated by alternative exon splicing
    W M Wood
    Department of Medicine, University of Colorado Health Sciences Center, Denver 80262
    Mol Endocrinol 1:875-83. 1987
    ..In the hypothyroid state, transcripts initiated at the upstream site were considerably less abundant than those initiated at the downstream site. Transcription from both start sites was inhibited by thyroid hormone in both mice and rats...
  13. ncbi request reprint Organization and nucleotide sequence of the mouse alpha-subunit gene of the pituitary glycoprotein hormones
    D F Gordon
    Department of Medicine, University of Colorado Health Sciences Center, Denver 80262
    DNA 7:679-90. 1988
    ....
  14. ncbi request reprint Role of glucocorticoid hormones in arginine vasopressin gene regulation
    J K Kim
    Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Biochem Biophys Res Commun 289:1252-6. 2001
    ..In conclusion, the data presented here support a central mechanism to explain, at least in part, the nonosmotic increase in AVP with glucocorticoid deficiency...
  15. ncbi request reprint Lipoprotein lipase gene expression in rat adipocytes is regulated by isoproterenol and insulin through different mechanisms
    M V Raynolds
    Department of Medicine, University of Colorado Health Sciences Center, Denver 80262
    Mol Endocrinol 4:1416-22. 1990
    ..Insulin, which does not affect LPL gene transcription, increases LPL enzyme activity and steady state mRNA levels. The effect of insulin on LPL mRNA is probably due to insulin-induced changes in mRNA stability...
  16. ncbi request reprint Signaling pathways responsible for fetal gene induction in the failing human heart: evidence for altered thyroid hormone receptor gene expression
    K Kinugawa
    Division of Cardiology, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Circulation 103:1089-94. 2001
    ....
  17. ncbi request reprint Isolation and characterization of mouse complementary DNAs encoding alpha and beta thyroid hormone receptors from thyrotrope cells: the mouse pituitary-specific beta 2 isoform differs at the amino terminus from the corresponding species from rat pituitary
    W M Wood
    Department of Medicine, University of Colorado Health Sciences Center, Denver 80262
    Mol Endocrinol 5:1049-61. 1991
    ..Levels of TR beta 1 mRNA were not changed in liver, but were increased in thyrotropic tumors and also somewhat in brain, an organ that is not responsive to T3 by classical criteria...
  18. ncbi request reprint Enhancer-mediated high level expression of mouse pituitary glycoprotein hormone alpha-subunit transgene in thyrotropes, gonadotropes, and developing pituitary gland
    S K Kendall
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48109 0618
    Mol Endocrinol 8:1420-33. 1994
    ....
  19. ncbi request reprint Chromosomal localization of the large subunit of mouse replication factor C in the mouse and human
    A C Lossie
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48109 0618
    Mamm Genome 6:58-9. 1995
  20. ncbi request reprint N-terminal variants of thyroid hormone receptor beta: differential function and potential contribution to syndrome of resistance to thyroid hormone
    L Ng
    Roche Institute of Molecular Biology, Nutley, New Jersey 07110, USA
    Mol Endocrinol 9:1202-13. 1995
    ....