D Woo

Summary

Affiliation: University of Cincinnati
Country: USA

Publications

  1. ncbi request reprint Subarachnoid hemorrhage: a preventable disease with a heritable component
    Brett M Kissela
    Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0525, USA
    Stroke 33:1321-6. 2002
  2. ncbi request reprint Stroke in a biracial population: the excess burden of stroke among blacks
    Brett Kissela
    Department of Neurology, Neuroscience Institute, University of Cincinnati, OH 45267 0525, USA
    Stroke 35:426-31. 2004
  3. pmc The use of standardized patients for mock oral board exams in neurology: a pilot study
    Brett Kissela
    Department of Neurology, University of Cincinnati, Cincinnati, OH 45267 0525, USA
    BMC Med Educ 6:22. 2006
  4. pmc Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage
    Daniel Woo
    Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA Electronic address
    Am J Hum Genet 94:511-21. 2014
  5. pmc Quantitative criteria for improving performance of buccal DNA for high-throughput genetic analysis
    Jessica G Woo
    Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    BMC Genet 13:75. 2012
  6. doi request reprint Location, interaction, and anticipation of aneurysm formation
    Daniel Woo
    Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0525, USA
    Acta Neurochir Suppl 115:279-80. 2013
  7. pmc Quality assessment of buccal versus blood genomic DNA using the Affymetrix 500 K GeneChip
    Jessica G Woo
    University of Cincinnati College of Medicine, 321 Albert Sabin Way, Cincinnati, OH 45267, USA
    BMC Genet 8:79. 2007
  8. pmc Age at intracranial aneurysm rupture among generations: Familial Intracranial Aneurysm Study
    D Woo
    Departments of Neurology, Environmental Health, and Center for Environmental Genetics, University of Cincinnati, Cincinnati, OH 45267 0525, USA
    Neurology 72:695-8. 2009
  9. ncbi request reprint Association of Phosphodiesterase 4D with ischemic stroke: a population-based case-control study
    Daniel Woo
    Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0525, USA
    Stroke 37:371-6. 2006
  10. pmc Smoking and family history and risk of aneurysmal subarachnoid hemorrhage
    D Woo
    Department of Neurology, University of Cincinnati College of Medicine, 260 Stetson Street ML 0525, Cincinnati, OH 45267 0525, USA
    Neurology 72:69-72. 2009

Research Grants

Detail Information

Publications65

  1. ncbi request reprint Subarachnoid hemorrhage: a preventable disease with a heritable component
    Brett M Kissela
    Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0525, USA
    Stroke 33:1321-6. 2002
    ..Prevention of SAH is therefore of paramount importance. We present a preliminary analysis of risk factors for SAH from our population-based, case-control study...
  2. ncbi request reprint Stroke in a biracial population: the excess burden of stroke among blacks
    Brett Kissela
    Department of Neurology, Neuroscience Institute, University of Cincinnati, OH 45267 0525, USA
    Stroke 35:426-31. 2004
    ..31 million people, which is representative of the US white and black populations with regard to many demographic and socioeconomic characteristics...
  3. pmc The use of standardized patients for mock oral board exams in neurology: a pilot study
    Brett Kissela
    Department of Neurology, University of Cincinnati, Cincinnati, OH 45267 0525, USA
    BMC Med Educ 6:22. 2006
    ..We sought to create a standardized patient mock oral board exam that would allow comparison of residents' clinical performance...
  4. pmc Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage
    Daniel Woo
    Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA Electronic address
    Am J Hum Genet 94:511-21. 2014
    ..2 × 10(-10)) but not for 12q21.1 (p = 0.55; meta-analysis p = 2.6 × 10(-5)). These results demonstrate biological heterogeneity across ICH subtypes and highlight the importance of ascertaining ICH cases accordingly...
  5. pmc Quantitative criteria for improving performance of buccal DNA for high-throughput genetic analysis
    Jessica G Woo
    Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
    BMC Genet 13:75. 2012
    ..phs.wfubmc.edu/public/index.cfm)...
  6. doi request reprint Location, interaction, and anticipation of aneurysm formation
    Daniel Woo
    Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0525, USA
    Acta Neurochir Suppl 115:279-80. 2013
    ..We review these three topics in detail and summarize what we gathered from this information...
  7. pmc Quality assessment of buccal versus blood genomic DNA using the Affymetrix 500 K GeneChip
    Jessica G Woo
    University of Cincinnati College of Medicine, 321 Albert Sabin Way, Cincinnati, OH 45267, USA
    BMC Genet 8:79. 2007
    ..We sought to describe the genomic DNA yield and concordance between stored buccal brushes and blood samples from the same individuals in the context of Affymetrix 500 K Human GeneChip genotyping...
  8. pmc Age at intracranial aneurysm rupture among generations: Familial Intracranial Aneurysm Study
    D Woo
    Departments of Neurology, Environmental Health, and Center for Environmental Genetics, University of Cincinnati, Cincinnati, OH 45267 0525, USA
    Neurology 72:695-8. 2009
    ..We examined families in which ruptured IA occurred in two consecutive generations for the hypothesis that the second generation (F1) was more likely to have a rupture at a younger age than the older generation (F0)...
  9. ncbi request reprint Association of Phosphodiesterase 4D with ischemic stroke: a population-based case-control study
    Daniel Woo
    Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0525, USA
    Stroke 37:371-6. 2006
    ..None of the reports included significant proportions of blacks. We tested for genotype and haplotype association of polymorphisms of the PDE4D gene with ischemic stroke in a population-based, biracial, case-control study...
  10. pmc Smoking and family history and risk of aneurysmal subarachnoid hemorrhage
    D Woo
    Department of Neurology, University of Cincinnati College of Medicine, 260 Stetson Street ML 0525, Cincinnati, OH 45267 0525, USA
    Neurology 72:69-72. 2009
    ..Using a population-based case-control study of hemorrhagic stroke, we hypothesized that having both a first-degree relative with a brain aneurysm or SAH (+FH) and current smoking interact to increase the risk of aSAH...
  11. ncbi request reprint Association of apolipoprotein E4 and haplotypes of the apolipoprotein E gene with lobar intracerebral hemorrhage
    Daniel Woo
    University of Cincinnati, Cincinnati, OH, USA
    Stroke 36:1874-9. 2005
    ..We genotyped 12 single-nucleotide polymorphisms in the 5' upstream regulatory, exonic, and intronic regions of the apo E gene and performed genotype and haplotype association analyses...
  12. ncbi request reprint Effect of untreated hypertension on hemorrhagic stroke
    Daniel Woo
    University of Cincinnati College of Medicine, 231 Albert Sabin Way, ML 0525, Cincinnati, OH 45267 0525, USA
    Stroke 35:1703-8. 2004
    ..Hypertension is an important risk factor for these subtypes of stroke. We sought to determine whether untreated hypertension carries a different risk from treated hypertension for hemorrhagic stroke...
  13. ncbi request reprint Hypercholesterolemia, HMG-CoA reductase inhibitors, and risk of intracerebral hemorrhage: a case-control study
    Daniel Woo
    Department of Neurology and the Neuroscience Institute, University of Cincinnati, College of Medicine, 231 Bethesda Avenue ML 0525, Cincinnati, Ohio 45267 0525, USA
    Stroke 35:1360-4. 2004
    ..We tested the hypothesis that hypercholesterolemia or use of HMG-CoA reductase inhibitors (statin) agents, or both, are associated with ICH...
  14. ncbi request reprint Does the National Institutes of Health Stroke Scale favor left hemisphere strokes? NINDS t-PA Stroke Study Group
    D Woo
    Department of Neurology, University of Cincinnati, Cincinnati, Ohio 45220, USA
    Stroke 30:2355-9. 1999
    ..Of 42 possible points, 7 points are directly related to measurement of language compared with only 2 points related to neglect...
  15. ncbi request reprint Incidence rates of first-ever ischemic stroke subtypes among blacks: a population-based study
    D Woo
    Departments of Neurology, Environmental Health, and Emergency Medicine, University of Cincinnati, OH 45267 0525, USA
    Stroke 30:2517-22. 1999
    ..The aim of this study was to determine the incidence rates of ischemic stroke subtypes among blacks...
  16. ncbi request reprint Genetic and environmental risk factors for intracerebral hemorrhage: preliminary results of a population-based study
    Daniel Woo
    Department of Neurology, University of Cincinnati, Cincinnati, Ohio 45267 0525, USA
    Stroke 33:1190-5. 2002
    ..We report a preplanned, midpoint analysis of the first population-based, case-control study that examines both genetic and environmental risk factors of ICH...
  17. ncbi request reprint Spontaneous intracerebral hemorrhage: epidemiology and clinical presentation
    Daniel Woo
    Department of Neurology, University of Cincinnati College of Medicine, 231 Albert Sabin Way, PO Box 670525, Cincinnati, OH 45267 0525, USA
    Neurosurg Clin N Am 13:265-79, v. 2002
    ..This article reviews the incidence rates, natural history, epidemiology, and clinical presentations of nontraumatic ICH...
  18. ncbi request reprint Greater Cincinnati/Northern Kentucky Stroke Study: volume of first-ever ischemic stroke among blacks in a population-based study
    B Kissela
    Department of Neurology, University of Cincinnati, OH 45267 0525, USA
    Stroke 32:1285-90. 2001
    ..The volume of ischemic stroke on CT scans has been studied in a standardized fashion in acute stroke therapy trials with median volumes between 10.5 to 55 cm(3). The volume of first-ever ischemic stroke in the population is not known...
  19. ncbi request reprint The increasing incidence of anticoagulant-associated intracerebral hemorrhage
    M L Flaherty
    Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0525, USA
    Neurology 68:116-21. 2007
    ..To define temporal trends in the incidence of anticoagulant-associated intracerebral hemorrhage (AAICH) during the 1990s and relate them to rates of cardioembolic ischemic stroke...
  20. pmc Warfarin use leads to larger intracerebral hematomas
    M L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, OH 45267 0525, USA
    Neurology 71:1084-9. 2008
    ..In a retrospective study, we sought to determine whether warfarin use is associated with larger initial hematoma volume, one determinant of mortality after ICH...
  21. ncbi request reprint Long-term mortality after intracerebral hemorrhage
    M L Flaherty
    Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
    Neurology 66:1182-6. 2006
    ..To characterize long-term mortality following intracerebral hemorrhage (ICH) in two large population-based cohorts assembled more than a decade apart...
  22. pmc Population-based study of wake-up strokes
    J Mackey
    University of Cincinnati, Department of Neurology, Cincinnati, OH 45219, USA
    Neurology 76:1662-7. 2011
    ..We sought to establish the proportion and event rate of wake-up strokes in a large population-based study and to compare patients who awoke with stroke symptoms with those who were awake at time of onset...
  23. ncbi request reprint Combined IV and intra-arterial thrombolysis for acute ischemic stroke
    M L Flaherty
    Department of Neurology, University of Cincinnati Medical Center, 231 Albert Sabin Way, MSB Rm 5161B, Cincinnati, OH, 45267 0525, USA
    Neurology 64:386-8. 2005
    ..Three-month modified Rankin Scale scores were 0 to 2 for 50% of patients, mortality was 18%, and symptomatic intracerebral hemorrhage occurred in 8%. IV/IA thrombolysis appeared safe and effective in this group...
  24. pmc Greater rupture risk for familial as compared to sporadic unruptured intracranial aneurysms
    Joseph P Broderick
    Department of Neurology, Center for Stroke and Cerebrovascular Disease, University of Cincinnati Neuroscience Institute, UC College of Medicine, 260 Stetson Street, Cincinnati, OH 45267 0525, USA
    Stroke 40:1952-7. 2009
    ..The risk of intracranial aneurysm (IA) rupture in asymptomatic members of families who have multiple affected individuals is not known...
  25. ncbi request reprint Association of ALOX5AP with ischemic stroke: a population-based case-control study
    Ritesh Kaushal
    Department of Environmental Health, Center for Genome Information, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0525, USA
    Hum Genet 121:601-7. 2007
    ..In conclusion, we report significant association of variants of ALOX5AP with ischemic stroke and ischemic stroke subtypes among whites. No significant association was identified among blacks...
  26. doi request reprint Age accounts for racial differences in ischemic stroke volume in a population-based study
    Tarek Zakaria
    Department of Neurology, University of Cincinnati, Cincinnati, Ohio 45267 0525, USA
    Cerebrovasc Dis 26:376-80. 2008
    ..5 cm. However, it is not known if stroke volume was similar between black and white patients within the same study population...
  27. pmc Which stroke symptoms prompt a 911 call? A population-based study
    Dawn Kleindorfer
    Department of Neurology, University of Cincinnati, Cincinnati, OH 45267 0525, USA
    Am J Emerg Med 28:607-12. 2010
    ..Most studies have found that less than half of stroke/transient ischemic attack (TIA) events result in a 911 call. We sought to determine which symptoms prompt the public to call 911...
  28. pmc Genome screen to detect linkage to common susceptibility genes for intracranial and aortic aneurysms
    Bradford B Worrall
    University of Virginia Health System, Department of Neurology, Box 800394, Charlottesville, VA 22908, USA
    Stroke 40:71-6. 2009
    ..We performed a genomewide linkage analysis in multiplex families with both IA and AA from the Familial Intracranial Aneurysm study...
  29. doi request reprint How important is surrogate consent for stroke research?
    M L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, 260 Stetson St, Room 2316, Cincinnati, OH 45267 0525, USA
    Neurology 71:1566-71. 2008
    ....
  30. pmc Prior antiplatelet therapy and outcome following intracerebral hemorrhage: a systematic review
    B B Thompson
    Department of Neurology, Brown University, Providence, RI, USA
    Neurology 75:1333-42. 2010
    ..We performed a systematic review and meta-analysis to address the hypothesis that pre-ICH APT use is associated with mortality and poor functional outcome following ICH...
  31. pmc Subarachnoid hemorrhage: tests of association with apolipoprotein E and elastin genes
    Ritesh Kaushal
    Department of Environmental Health, Center for Genome Information, University of Cincinnati, Cincinnati, Ohio, USA
    BMC Med Genet 8:49. 2007
    ..Associations were tested at genotype, allele, and haplotype levels. A genomic control analysis was performed to check for spurious associations resulting from population substructure...
  32. ncbi request reprint Early carotid endarterectomy for critical carotid artery stenosis after thrombolysis therapy in acute ischemic stroke in the middle cerebral artery
    C M McPherson
    Neuroscience Institute, University of Cincinnati, Department of Neurosurgery, Cincinnati, Ohio, USA
    Stroke 32:2075-80. 2001
    ..CONCLUSIONS: Early CEA can be performed safely and successfully in patients after tPA treatment for acute ischemic stroke in appropriately selected patients...
  33. ncbi request reprint Incidence of seizures in the acute phase of stroke: a population-based study
    Jerzy P Szaflarski
    Department of Neurology and the Neuroscience Institute, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
    Epilepsia 49:974-81. 2008
    ..We aimed to establish the incidence of acute poststroke seizures in a biracial cohort and to determine whether acute seizure occurrence differs by race/ethnicity, stroke subtype, and/or stroke localization...
  34. pmc How much would performing diffusion-weighted imaging for all transient ischemic attacks increase MRI utilization?
    Opeolu Adeoye
    Departments of Emergency Medicine and Neurosurgery, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
    Stroke 41:2218-22. 2010
    ..We determined how frequently MRI/DWI was performed for TIA and ascertained the proportion of clinically defined TIA patients who had ischemic lesions on DWI in our community in 2005...
  35. pmc Stroke incidence is decreasing in whites but not in blacks: a population-based estimate of temporal trends in stroke incidence from the Greater Cincinnati/Northern Kentucky Stroke Study
    Dawn O Kleindorfer
    Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45242, USA
    Stroke 41:1326-31. 2010
    ..The objective of this study was to examine temporal trends in stroke incidence and case-fatality within a large biracial population over time by comparing stroke incidence rates from 1993 to 1994, 1999, and 2005...
  36. pmc The combined approach to lysis utilizing eptifibatide and rt-PA in acute ischemic stroke: the CLEAR stroke trial
    Arthur M Pancioli
    Department of Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0769, USA
    Stroke 39:3268-76. 2008
    ....
  37. pmc The effects of study participation in the Familial Intracranial Aneurysm Study on cigarette smoking
    Laura R Sauerbeck
    Department of Neurology, University of Cincinnati, Ohio 45267 0525, USA
    J Stroke Cerebrovasc Dis 17:370-2. 2008
    ..Cigarette smoking is the most modifiable risk factor for the formation and rupture of intracranial aneurysm (IA). This study examined the impact of participation in the Familial IA study on smoking behavior...
  38. pmc Temporal trends in public awareness of stroke: warning signs, risk factors, and treatment
    Dawn Kleindorfer
    Department of Neurology, University of Cincinnati, Cincinnati, OH 45267, USA
    Stroke 40:2502-6. 2009
    ..We describe public knowledge of t-PA as a treatment for IS, as well as changes over time in knowledge of stroke warning signs (WS) and risk factors (RF)...
  39. pmc The challenge of designing a treatment trial for warfarin-associated intracerebral hemorrhage
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
    Stroke 40:1738-42. 2009
    ..We determined the number of patients that would be eligible for enrollment in hypothetical treatment trials for WICH using a population-based study...
  40. pmc Surgical management and case-fatality rates of intracerebral hemorrhage in 1988 and 2005
    Opeolu Adeoye
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio 45267 0525, USA
    Neurosurgery 63:1113-7; discussion 1117-8. 2008
    ..To compare surgical management and case-fatality rates of intracerebral hemorrhage (ICH) in 1988 and 2005...
  41. pmc Clinical prediction of functional outcome after ischemic stroke: the surprising importance of periventricular white matter disease and race
    Brett Kissela
    Department of Neurology, University of Cincinnati, Ohio, USA
    Stroke 40:530-6. 2009
    ....
  42. pmc Eligibility for the surgical trial in intracerebral hemorrhage II study in a population-based cohort
    Opeolu Adeoye
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
    Neurocrit Care 9:237-41. 2008
    ..We sought to determine how many patients in a population-based ICH cohort would have been eligible for surgery using the Surgical Trial in Intracerebral Hemorrhage II (STICH II) criteria...
  43. ncbi request reprint Ischemic stroke subtypes: a population-based study of incidence rates among blacks and whites
    Alexander T Schneider
    Department of Neurology and the Neuroscience Institute, 231 Albert Sabin Way, University of Cincinnati, ML 0525, Cincinnati, Ohio 45267, USA
    Stroke 35:1552-6. 2004
    ..The objective of this study is to compare the incidence rates of ischemic stroke subtypes between blacks and whites within a large, representative, biracial population...
  44. ncbi request reprint Epidemiology of ischemic stroke in patients with diabetes: the greater Cincinnati/Northern Kentucky Stroke Study
    Brett M Kissela
    Department of Neurology, University of Cincinnati, 231 Albert Sabin Way, ML 0525, Cincinnati, OH 45267 0525, USA
    Diabetes Care 28:355-9. 2005
    ..Diabetes is a well known risk factor for stroke, but the impact of diabetes on stroke incidence rates is not known. This study uses a population-based study to describe the epidemiology of ischemic stroke in diabetic patients...
  45. ncbi request reprint A description of Canadian and United States physician reimbursement for thrombolytic therapy administration in acute ischemic stroke
    Dawn Kleindorfer
    Department of Neurology, University of Cincinnati College of Medicine, 231 Albert Sabin Way ML0525, Cincinnati, Ohio 45267 0525, USA
    Stroke 36:682-7. 2005
    ..We describe the physician reimbursement for thrombolytic therapy for the stroke team physicians serving the Greater Cincinnati/Northern Kentucky region (GCNK), and the Alberta region...
  46. ncbi request reprint Incidence and short-term prognosis of transient ischemic attack in a population-based study
    Dawn Kleindorfer
    Department of Emergency Medicine, University of Cincinnati, Ohio, USA
    Stroke 36:720-3. 2005
    ..We present the incidence and short-term prognosis of TIA within a large population with a significant proportion of minorities with out-of-hospital TIA...
  47. ncbi request reprint Racial variations in location and risk of intracerebral hemorrhage
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Medical Center, Ohio 45267 0525, USA
    Stroke 36:934-7. 2005
    ..Incidence rates of ICH are known to be higher in American blacks than whites, but how rates may differ by hemorrhage location is unknown. We sought to define incidence rates for different ICH locations in a biracial population...
  48. ncbi request reprint Potential applicability of recombinant factor VIIa for intracerebral hemorrhage
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
    Stroke 36:2660-4. 2005
    ..We sought to determine the potential applicability of rFVIIa in a large, population-based cohort of ICH patients...
  49. ncbi request reprint Smoking cessation after stroke: education and its effect on behavior
    Laura R Sauerbeck
    University of Cincinnati, OH, USA
    J Neurosci Nurs 37:316-9, 325. 2005
    ..Further research is needed to determine whether this behavior continues beyond 3 months and to determine why some stroke survivors continue to smoke...
  50. ncbi request reprint Community socioeconomic status and prehospital times in acute stroke and transient ischemic attack: do poorer patients have longer delays from 911 call to the emergency department?
    Dawn O Kleindorfer
    Department of Neurology, The Institute for the Study of Health, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0525, USA
    Stroke 37:1508-13. 2006
    ..We examined the effect of socioeconomic status on prehospital delays in stroke and transient ischemic attack (TIA) patients within a large, biracial population...
  51. ncbi request reprint Temporal trends in the incidence and case fatality of stroke in children and adolescents
    Dawn Kleindorfer
    Department of Neurology, University of Cincinnati College of Medicine, OH 45267 0525, USA
    J Child Neurol 21:415-8. 2006
    ..Based on our data, we conservatively estimated that approximately 3000 children less than 20 years old would have a stroke in the United States in 2004...
  52. ncbi request reprint The unchanging incidence and case-fatality of stroke in the 1990s: a population-based study
    Dawn Kleindorfer
    University of Cincinnati, 231 Albert Sabin Way ML 0525, Cincinnati, OH 45267 0525, USA
    Stroke 37:2473-8. 2006
    ..The objective of this study was to examine temporal trends in stroke incidence and case-fatality within a large, biracial population during the 1990s...
  53. ncbi request reprint Impact of socioeconomic status on stroke incidence: a population-based study
    Dawn O Kleindorfer
    Department of Neurology, University of Cincinnati, Cincinnati, OH, USA
    Ann Neurol 60:480-4. 2006
  54. ncbi request reprint Trends in community knowledge of the warning signs and risk factors for stroke
    Alexander T Schneider
    Department of Neurology, University of Cincinnati, Medical Science Bldg No 0525, 231 Albert Sabin Way, Cincinnati, Ohio 45267, USA
    JAMA 289:343-6. 2003
    ..Poor public knowledge of stroke warning signs and risk factors limits effective stroke intervention and prevention...
  55. ncbi request reprint Emergency department arrival times after acute ischemic stroke during the 1990s
    Dawn O Kleindorfer
    University of Cincinnati Medical Center, 231 Albert Sabin Way, MSB Room 5059A, Cincinnati, OH 45267 0525, USA
    Neurocrit Care 7:31-5. 2007
    ..We sought to investigate whether patients are arriving to the ED more quickly in 1999 than in 1993/94 within our large biracial population of 1.3 million...
  56. ncbi request reprint Eligibility for recombinant tissue plasminogen activator in acute ischemic stroke: a population-based study
    Dawn Kleindorfer
    Department of Neurology, University of Cincinnati College of Medicine, The Neuroscience Institute, OH 45267, USA
    Stroke 35:e27-9. 2004
    ..Acute ischemic stroke patients are infrequently treated with recombinant tissue plasminogen activator (rtPA). We present unique population-based data regarding the eligibility of ischemic stroke patients for rtPA treatment...
  57. ncbi request reprint Location and outcome of anticoagulant-associated intracerebral hemorrhage
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
    Neurocrit Care 5:197-201. 2006
    ..The characteristics of patients with anticoagulant-associated intracerebral hemorrhage (AAICH) have not been well characterized in a population-based setting...
  58. doi request reprint Screening for brain aneurysm in the Familial Intracranial Aneurysm study: frequency and predictors of lesion detection
    Robert D Brown
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    J Neurosurg 108:1132-8. 2008
    ..A better understanding of predictors of aneurysm detection in familial IA may allow more targeted aneurysm screening strategies...
  59. pmc The relationship between smoking and replicated sequence variants on chromosomes 8 and 9 with familial intracranial aneurysm
    Ranjan Deka
    Department of Neurology, UC Neuroscience Institute, University of Cincinnati Academic Health Center, 260 Stetson Street, Suite 2300, PO Box 670525, Cincinnati, OH 45267 0525, USA
    Stroke 41:1132-7. 2010
    ..The purpose of this study was to replicate the previous association of single nucleotide polymorphisms (SNPs) with risk of intracranial aneurysm (IA) and to examine the relationship of smoking with these variants and the risk of IA...
  60. ncbi request reprint Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease
    Victoria Busby
    Department of Neuroscience, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
    Neuromolecular Med 5:133-46. 2004
    ..None of these SNPs was associated with disease. Although an excellent candidate, we conclude that CTNNA3 is unlikely to account for the AD susceptibility locus on chromosome 10...
  61. ncbi request reprint The incidence of deep and lobar intracerebral hemorrhage in whites, blacks, and Hispanics
    Matthew L Flaherty
    Neurology 66:956-7; author reply 956-7. 2006
  62. ncbi request reprint The role of race in time to treatment after subarachnoid hemorrhage
    Sonia V Eden
    Neurosurgery 60:837-43; discussion 837-43. 2007
    ..The time to treatment for aneurysmal SAH has been found to correlate with mortality and outcome. Therefore, we examined racial differences in the time to treatment of aneurysmal SAH among patients from the Greater Cincinnati area...
  63. ncbi request reprint Designing a message for public education regarding stroke: does FAST capture enough stroke?
    Dawn O Kleindorfer
    Stroke 38:2864-8. 2007
    ..We sought to assess the percentage of stroke/transient ischemic attack (TIA) patients identified by both public awareness messages by examining presenting symptoms of all stroke/TIA patients from a large, biracial population in 1999...
  64. pmc Genome screen to detect linkage to intracranial aneurysm susceptibility genes: the Familial Intracranial Aneurysm (FIA) study
    Tatiana Foroud
    Indiana University School of Medicine, Health Information and Translational Sciences Building HS 4000, 410 West 10th Street, Indianapolis, IN 46202 3002, USA
    Stroke 39:1434-40. 2008
    ..Evidence supports a substantial genetic contribution to the risk of intracranial aneurysm (IA). The purpose of this study was to identify chromosomal regions likely to harbor genes that contribute to the risk of IA...
  65. ncbi request reprint Selective serotonin reuptake inhibitors and risk of hemorrhagic stroke
    Jordan Kharofa
    Stroke 38:3049-51. 2007
    ..Selective serotonin reuptake inhibitors (SSRI) are widely prescribed. Several reports have observed an increased bleeding risk associated with SSRI use, which is hypothesized to be secondary to their antiplatelet effect...

Research Grants4

  1. Familial Aggregation of Stroke
    Daniel Woo; Fiscal Year: 2005
    ..Determining the component of the familial aggregation of ICH that is independent of the familial aggregation of environmental risk factors is a fundamental step in the analysis of the genetic epidemiology of stroke. ..
  2. Genetic and Environmental Risk Factors for Hemorrhagic Stroke
    Daniel Woo; Fiscal Year: 2009
    ....
  3. Genetic and Environmental Risk Factors for Hemorrhagic Stroke
    Daniel Woo; Fiscal Year: 2010
    ....