N D Wong

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Screening and risk stratification of patients with the metabolic syndrome and diabetes
    Nathan D Wong
    University of California, Heart Disease Prevention Program, C240 Medical Sciences, Irvine, CA 92697, USA
    Expert Rev Cardiovasc Ther 4:181-90. 2006
  2. ncbi request reprint Metabolic syndrome: cardiovascular risk assessment and management
    Nathan D Wong
    Heart Disease Prevention Program, Department of Medicine, University of California, Irvine, California 92697, USA
    Am J Cardiovasc Drugs 7:259-72. 2007
  3. pmc Impact of subclinical atherosclerosis on cardiovascular disease events in individuals with metabolic syndrome and diabetes: the multi-ethnic study of atherosclerosis
    Shaista Malik
    Heart Disease Prevention Program, Division of Cardiology, University of California Irvine, Irvine, California, USA
    Diabetes Care 34:2285-90. 2011
  4. ncbi request reprint Preventable coronary heart disease events from control of cardiovascular risk factors in US adults with diabetes (projections from utilizing the UKPDS risk engine)
    Nathan D Wong
    Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, California Electronic address
    Am J Cardiol 113:1356-61. 2014
  5. pmc Genetics of coronary artery calcification among African Americans, a meta-analysis
    Mary K Wojczynski
    Department of Genetics, Division of Statistical Genomics, Washington University School of Medicine, St Louis, MO, USA
    BMC Med Genet 14:75. 2013
  6. doi request reprint Residual dyslipidemia among United States adults treated with lipid modifying therapy (data from National Health and Nutrition Examination Survey 2009-2010)
    Nathan D Wong
    Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, CA, USA
    Am J Cardiol 112:373-9. 2013
  7. pmc Metabolic syndrome, diabetes, and incidence and progression of coronary calcium: the Multiethnic Study of Atherosclerosis study
    Nathan D Wong
    Department of Medicine, University of California, Irvine, California 92697 4101, USA
    JACC Cardiovasc Imaging 5:358-66. 2012
  8. doi request reprint Global cardiovascular risk associated with hypertension and extent of treatment and control according to risk group
    Nathan D Wong
    Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, California, USA
    Am J Hypertens 25:561-7. 2012
  9. doi request reprint Global cardiovascular disease risk assessment in United States adults with diabetes
    Nathan D Wong
    Heart Disease Prevention Program, Division of Cardiology, University of California, 112 Sprague Hall, Irvine, CA 92697, USA
    Diab Vasc Dis Res 9:146-52. 2012
  10. pmc Do risk factors explain the increased prevalence of type 2 diabetes among California Asian adults?
    Sarah E Choi
    Program in Nursing Science, College of Health Sciences, University of California, Irvine, CA 92697 3959, USA
    J Immigr Minor Health 13:803-8. 2011

Collaborators

Detail Information

Publications107 found, 100 shown here

  1. ncbi request reprint Screening and risk stratification of patients with the metabolic syndrome and diabetes
    Nathan D Wong
    University of California, Heart Disease Prevention Program, C240 Medical Sciences, Irvine, CA 92697, USA
    Expert Rev Cardiovasc Ther 4:181-90. 2006
    ..The presence of subclinical atherosclerosis or elevated levels of C-reactive protein can potentially modify recommended treatment goals for lipid and other cardiovascular risk factors...
  2. ncbi request reprint Metabolic syndrome: cardiovascular risk assessment and management
    Nathan D Wong
    Heart Disease Prevention Program, Department of Medicine, University of California, Irvine, California 92697, USA
    Am J Cardiovasc Drugs 7:259-72. 2007
    ....
  3. pmc Impact of subclinical atherosclerosis on cardiovascular disease events in individuals with metabolic syndrome and diabetes: the multi-ethnic study of atherosclerosis
    Shaista Malik
    Heart Disease Prevention Program, Division of Cardiology, University of California Irvine, Irvine, California, USA
    Diabetes Care 34:2285-90. 2011
    ..We evaluated whether screening for coronary artery calcium (CAC) and carotid intimal-medial thickness (CIMT) can improve CVD risk stratification over traditional risk factors (RFs) in people with MetS and diabetes...
  4. ncbi request reprint Preventable coronary heart disease events from control of cardiovascular risk factors in US adults with diabetes (projections from utilizing the UKPDS risk engine)
    Nathan D Wong
    Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, California Electronic address
    Am J Cardiol 113:1356-61. 2014
    ..In conclusion, a significant proportion of CHD events in adults with T2DM could be prevented from composite control of risk factors often not at goal...
  5. pmc Genetics of coronary artery calcification among African Americans, a meta-analysis
    Mary K Wojczynski
    Department of Genetics, Division of Statistical Genomics, Washington University School of Medicine, St Louis, MO, USA
    BMC Med Genet 14:75. 2013
    ..African Americans (AA) have higher rates of CHD but are less well-studied in genomic studies. We assembled the largest AA data resource currently available with measured CAC to identify associated genetic variants...
  6. doi request reprint Residual dyslipidemia among United States adults treated with lipid modifying therapy (data from National Health and Nutrition Examination Survey 2009-2010)
    Nathan D Wong
    Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, CA, USA
    Am J Cardiol 112:373-9. 2013
    ....
  7. pmc Metabolic syndrome, diabetes, and incidence and progression of coronary calcium: the Multiethnic Study of Atherosclerosis study
    Nathan D Wong
    Department of Medicine, University of California, Irvine, California 92697 4101, USA
    JACC Cardiovasc Imaging 5:358-66. 2012
    ..This study sought to examine and compare the incidence and progression of coronary artery calcium (CAC) among persons with metabolic syndrome (MetS) and diabetes mellitus (DM) versus those with neither condition...
  8. doi request reprint Global cardiovascular risk associated with hypertension and extent of treatment and control according to risk group
    Nathan D Wong
    Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, California, USA
    Am J Hypertens 25:561-7. 2012
    ..We examined CVD risk distribution and treatment and control patterns according to risk group...
  9. doi request reprint Global cardiovascular disease risk assessment in United States adults with diabetes
    Nathan D Wong
    Heart Disease Prevention Program, Division of Cardiology, University of California, 112 Sprague Hall, Irvine, CA 92697, USA
    Diab Vasc Dis Res 9:146-52. 2012
    ..Diabetes mellitus (DM) is often considered a risk equivalent for cardiovascular disease (CVD); however, the variation in CVD risk in adults with DM has not been described...
  10. pmc Do risk factors explain the increased prevalence of type 2 diabetes among California Asian adults?
    Sarah E Choi
    Program in Nursing Science, College of Health Sciences, University of California, Irvine, CA 92697 3959, USA
    J Immigr Minor Health 13:803-8. 2011
    ..6-1.75 greater likelihood of DM compared to Caucasians...
  11. pmc Endothelial function and urine albumin levels among asymptomatic Mexican-Americans and non-Hispanic whites
    Julius M Gardin
    Division of Cardiology, Department of Medicine, St, John Hospital and Medical Center, Detroit, MI 48236, USA
    Cardiovasc Ultrasound 6:43. 2008
    ..Our aim was to help explain this apparent paradox by evaluating endothelial function and urine albumin levels in MA and NHW...
  12. ncbi request reprint Preventing coronary events by optimal control of blood pressure and lipids in patients with the metabolic syndrome
    Nathan D Wong
    Heart Disease Prevention Program, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
    Am J Cardiol 91:1421-6. 2003
    ..6% for women; control to optimal levels resulted in preventing 80.5% and 82.1% of events, respectively. Thus, many CHD events in patients with MetS may be preventable by nominal or optimal control of lipids and/or blood pressure...
  13. ncbi request reprint Inadequate control of hypertension in US adults with cardiovascular disease comorbidities in 2003-2004
    Nathan D Wong
    Heart Disease Prevention Program, Department of Medicine, University of California, C240 Medical Sciences, Irvine, CA 92697, USA
    Arch Intern Med 167:2431-6. 2007
    ....
  14. pmc Abdominal aortic calcium and multi-site atherosclerosis: the Multiethnic Study of Atherosclerosis
    Nathan D Wong
    Department of Medicine, University of CA, Irvine, CA 92697 4101, United States
    Atherosclerosis 214:436-41. 2011
    ..Abdominal aortic calcification (AAC) is a measure of subclinical cardiovascular disease (CVD). Data are limited regarding its relation to other measures of atherosclerosis...
  15. ncbi request reprint Intensified screening and treatment of the metabolic syndrome for cardiovascular risk reduction
    Nathan D Wong
    Heart Disease Prevention Program, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
    Prev Cardiol 8:47-52; quiz 53-4. 2005
    ..Clinicians are recommended to assess MetS in their routine practice and to intensify efforts to adequately treat accompanying lifestyle and clinical risk factors...
  16. pmc Combined association of lipids and blood pressure in relation to incident cardiovascular disease in the elderly: the cardiovascular health study
    Nathan D Wong
    Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, California, USA
    Am J Hypertens 23:161-7. 2010
    ..Hypertension and dyslipidemia are highly prevalent in the elderly. We studied the combined impact of both conditions on cardiovascular disease (CVD) events...
  17. ncbi request reprint Coronary calcium and cardiovascular event risk: evaluation by age- and sex-specific quartiles
    Nathan D Wong
    Heart Disease Prevention Program, University of California, Irvine, CA 92697, USA
    Am Heart J 143:456-9. 2002
    ....
  18. ncbi request reprint Preventing heart disease by controlling hypertension: impact of hypertensive subtype, stage, age, and sex
    Nathan D Wong
    Heart Disease Prevention Program, University of California, Irvine, Calif 92697, USA
    Am Heart J 145:888-95. 2003
    ..Hypertension is related to significant morbidity and mortality rates from coronary heart disease (CHD). This report examines the relative and absolute impact on risk for CHD by controlling hypertension to high normal and optimal levels...
  19. ncbi request reprint Coronary artery calcium evaluation by electron beam computed tomography and its relation to new cardiovascular events
    N D Wong
    Division of Cardiology, University of California, Irvine 92697, USA
    Am J Cardiol 86:495-8. 2000
    ..5 (p <0.05) and 8.8 (p <0.001), respectively. These data support previous reports showing CAC to be a modest predictor of future cardiovascular events...
  20. ncbi request reprint Surrogate measures of atherosclerosis and implications for evaluating cardiovascular risk
    Nathan D Wong
    Heart Disease Prevention Program, University of California, Irvine, CA 92697, USA
    Diabetes Obes Metab 5:73-80. 2003
  21. ncbi request reprint Prevalence, treatment, and control of combined hypertension and hypercholesterolemia in the United States
    Nathan D Wong
    Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, School of Medicine, Irvine, California, USA
    Am J Cardiol 98:204-8. 2006
    ..5% to 16%). In conclusion, treatment and control of combined hypertension and hypercholesterolemia are suboptimal. Increased efforts to improve treatment of these conditions are needed...
  22. ncbi request reprint Is pulse pressure useful in predicting risk for coronary heart Disease? The Framingham heart study
    S S Franklin
    Heart Disease Prevention Program, University of California, Irvine, USA
    Circulation 100:354-60. 1999
    ..We examined whether PP adds useful information for predicting coronary heart disease (CHD) in the population-based Framingham Heart Study...
  23. ncbi request reprint Prognostic accuracy of B-natriuretic peptide measurements and coronary artery calcium in asymptomatic subjects (from the Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research [EISNER] study)
    Leslee J Shaw
    Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
    Am J Cardiol 104:1245-50. 2009
    ..4% and 35.7% of CV events in patients with hypertension and in elderly patients beyond the Framingham risk score. In conclusion, BNP and CAC are independently predictive of CV events...
  24. ncbi request reprint Relation of thoracic aortic and aortic valve calcium to coronary artery calcium and risk assessment
    Nathan D Wong
    Heart Disease Prevention Program, Department of Medicine, University of California, Irvine, California, USA
    Am J Cardiol 92:951-5. 2003
    ....
  25. ncbi request reprint Coronary calcium does not accurately predict near-term future coronary events in high-risk adults
    R C Detrano
    Division of Cardiology, Department of Medicine, Harbor UCLA Medical Center, Torrance, CA 90502 2064, USA
    Circulation 99:2633-8. 1999
    ..In addition, we assessed the predictive value of a risk model that included calcium score and cardiac risk-factor data...
  26. ncbi request reprint Does the relation of blood pressure to coronary heart disease risk change with aging? The Framingham Heart Study
    S S Franklin
    Preventive Cardiology Program, University of California, Irvine 92697, USA
    Circulation 103:1245-9. 2001
    ..We examined the relative importance of diastolic (DBP), systolic (SBP) and pulse pressure (PP) as predictors of coronary heart disease (CHD) risk in different age groups of Framingham Heart Study participants...
  27. ncbi request reprint Predominance of isolated systolic hypertension among middle-aged and elderly US hypertensives: analysis based on National Health and Nutrition Examination Survey (NHANES) III
    S S Franklin
    Heart Disease Prevention Program, University of California, Irvine, CA 92697, USA
    Hypertension 37:869-74. 2001
    ..Better awareness of this middle-aged and older high-risk group and more aggressive antihypertensive therapy are necessary to address this treatment gap...
  28. ncbi request reprint Cardiovascular disease in U.S. patients with metabolic syndrome, diabetes, and elevated C-reactive protein
    Shaista Malik
    Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
    Diabetes Care 28:690-3. 2005
    ..We evaluated whether elevated CRP levels modify the relationship of metabolic syndrome and diabetes with CVD in U.S. adults...
  29. doi request reprint Thoracic aortic calcium versus coronary artery calcium for the prediction of coronary heart disease and cardiovascular disease events
    Nathan D Wong
    Division of Cardiology, University of California, Irvine, California, USA
    JACC Cardiovasc Imaging 2:319-26. 2009
    ..This study compared the ability of coronary artery calcium (CAC) and thoracic aortic calcium (TAC) to predict coronary heart disease (CHD) and cardiovascular disease (CVD) events...
  30. doi request reprint Myeloperoxidase, subclinical atherosclerosis, and cardiovascular disease events
    Nathan D Wong
    Division of Cardiology, University of California, Irvine, California, USA
    JACC Cardiovasc Imaging 2:1093-9. 2009
    ..We evaluated whether myeloperoxidase (MPO) predicts future cardiovascular disease (CVD) events in asymptomatic adults and whether subclinical atherosclerosis may affect this relation...
  31. doi request reprint Association of combinations of lipid parameters with carotid intima-media thickness and coronary artery calcium in the MESA (Multi-Ethnic Study of Atherosclerosis)
    Pathmaja Paramsothy
    Division of Cardiology, Department of Internal Medicine, University of Washington, Seattle, Washington 98104, USA
    J Am Coll Cardiol 56:1034-41. 2010
    ..The purpose of this study was to determine the association of combinations of lipid parameters with subclinical atherosclerosis...
  32. ncbi request reprint The metabolic syndrome, diabetes, and subclinical atherosclerosis assessed by coronary calcium
    Nathan D Wong
    Heart Disease Prevention Program, University of California, Irvine, California, USA
    J Am Coll Cardiol 41:1547-53. 2003
    ..We compared the prevalence and extent of coronary artery calcium (CAC) among persons with the metabolic syndrome (MetS), diabetes, and neither condition...
  33. doi request reprint Coronary calcium as a predictor of coronary events in four racial or ethnic groups
    Robert Detrano
    Department of Radiological Sciences, University of California at Irvine, Irvine, CA 92697, USA
    N Engl J Med 358:1336-45. 2008
    ..However, it is not known whether coronary-artery calcium predicts coronary heart disease in other racial or ethnic groups...
  34. doi request reprint Forced vital capacity paired with Framingham Risk Score for prediction of all-cause mortality
    H M Lee
    Division of Cardiology, Dept of Medicine, 115 Sprague Hall, University of California, Irvine, CA 92697, USA
    Eur Respir J 36:1002-6. 2010
    ..58; p<0.05). Similar results were obtained for FEV(1). Evaluation of lung function may be useful to improve risk stratification in persons with intermediate CHD risk where it adds to prediction of mortality over global risk assessment...
  35. ncbi request reprint Undertreatment of cardiovascular risk factors among persons with diabetes in the United States
    Shaista Malik
    Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, CA 92697, USA
    Diabetes Res Clin Pract 77:126-33. 2007
    ..We examined the extent of control of cardiovascular risk factors and distance from goal for those with uncontrolled levels in a recent sample of U.S. adults with diabetes...
  36. ncbi request reprint Value of coronary artery calcium scanning by computed tomography for predicting coronary heart disease in diabetic subjects
    Wenchun Qu
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Diabetes Care 26:905-10. 2003
    ..This is a report of the relative risk (RR) for outcomes of coronary artery calcium in diabetic and nondiabetic subjects...
  37. ncbi request reprint Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults
    Shaista Malik
    Heart Disease Prevention Program, University of California, Irvine 92697, USA
    Circulation 110:1245-50. 2004
    ..We examined the impact of MetS on CHD, CVD, and overall mortality among US adults...
  38. ncbi request reprint Cardiovascular comorbidities and blood pressure control in stroke survivors
    Manoj Kesarwani
    Heart Disease Prevention Program, Division of Cardiology, Department ofMedicine, University of California, Irvine, California 92697 4101, USA
    J Hypertens 27:1056-63. 2009
    ..To examine the association of cardiovascular(CV) comorbidities with the likelihood of being a stroke survivor and to determine the prevalence, treatment, and control of hypertension in this population...
  39. doi request reprint Prevalence and extent of dyslipidemia and recommended lipid levels in US adults with and without cardiovascular comorbidities: the National Health and Nutrition Examination Survey 2003-2004
    Heli Ghandehari
    Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, CA 92697, USA
    Am Heart J 156:112-9. 2008
    ..We evaluated the proportion of US adults with and without these conditions at (and distance to) recommended levels of LDL-C, non-high-density lipoprotein cholesterol (non-HDL-C), HDL-C, and triglycerides...
  40. ncbi request reprint Metabolic and clinical outcomes in nondiabetic individuals with the metabolic syndrome assigned to chlorthalidone, amlodipine, or lisinopril as initial treatment for hypertension: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent
    Henry R Black
    New York University School of Medicine, New York, New York, USA
    Diabetes Care 31:353-60. 2008
    ..Optimal initial antihypertensive drug therapy in people with the metabolic syndrome is unknown...
  41. ncbi request reprint Comparison of atherosclerotic calcification burden in persons with the cardiometabolic syndrome and diabetes
    Nathan D Wong
    Department of Imaging and Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Cardiometab Syndr 1:90-4. 2006
    ..52-2.90) for CAC and 1.14 (0.91-1.42), 1.03 (0.77-1.37), 1.03 (0.68-1.54), and 1.41 (1.03-1.92) for TAC. Multiple CMS risk factors are associated with increased CAC, but not TAC; DM with CMS has the highest prevalence of CAC and TAC...
  42. ncbi request reprint M-mode echocardiographic predictors of six- to seven-year incidence of coronary heart disease, stroke, congestive heart failure, and mortality in an elderly cohort (the Cardiovascular Health Study)
    J M Gardin
    Division of Cardiology, Department of Medicine, University of California, Irvine, California, USA
    Am J Cardiol 87:1051-7. 2001
    ....
  43. ncbi request reprint Left ventricular mass in the elderly. The Cardiovascular Health Study
    J M Gardin
    Department of Medicine, University of California, Irvine, USA
    Hypertension 29:1095-103. 1997
    ....
  44. ncbi request reprint Blood pressure categories, hypertensive subtypes, and the metabolic syndrome
    Stanley S Franklin
    Heart Disease Prevention Program, University of California, Irvine, California 92697, USA
    J Hypertens 24:2009-16. 2006
    ..Elevated blood pressure (BP) is one element of metabolic syndrome (MetS); however, the relation of various BP categories and hypertension subtypes to the likelihood of having MetS is not well defined...
  45. ncbi request reprint Measures of coronary artery calcification and association with the metabolic syndrome and diabetes
    Uzoma N Ibebuogu
    Division of Cardiology, Medical College of Georgia, Augusta, GA, USA
    J Cardiometab Syndr 4:6-11. 2009
    ..In addition, the presence of the metabolic syndrome or DM with increased FRS has incremental value over the FRS, DM, or the metabolic syndrome alone in predicting significant CAC...
  46. pmc Risk factor differences for aortic versus coronary calcified atherosclerosis: the multiethnic study of atherosclerosis
    Michael H Criqui
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093 0607, USA
    Arterioscler Thromb Vasc Biol 30:2289-96. 2010
    ..The goal of this study was to compare and contrast coronary artery calcium (CAC) with abdominal aortic calcium (AAC) in terms of their associations with traditional and novel cardiovascular disease (CVD) risk factors...
  47. pmc Global coronary heart disease risk assessment of individuals with the metabolic syndrome in the U.S
    Khiet C Hoang
    Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, California, USA
    Diabetes Care 31:1405-9. 2008
    ..This study describes the distribution of 10-year CHD risk among U.S. adults with metabolic syndrome...
  48. ncbi request reprint Impact of C-reactive protein on the likelihood of peripheral arterial disease in United States adults with the metabolic syndrome, diabetes mellitus, and preexisting cardiovascular disease
    John D Vu
    Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, School of Medicine, Irvine, California, USA
    Am J Cardiol 96:655-8. 2005
    ..6, 95% confidence interval 2.2 to 34.0, p = 0.001). In conclusion, the likelihood of PAD in US adults with MS and DM is enhanced by elevated CRP levels...
  49. ncbi request reprint Characteristics and lipid distribution of a large, high-risk, hypertensive population: the lipid-lowering component of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
    Vasilios Papademetriou
    Veterans Affairs Medical Center, Washington, DC 20422, USA
    J Clin Hypertens (Greenwich) 5:377-84. 2003
    ..The success of the randomization of this large, diverse population and the differences in the lipid distributions among its subgroups will allow further understanding of optimal lipid-lowering treatment...
  50. pmc The effect of intensive glycemic treatment on coronary artery calcification in type 1 diabetic participants of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study
    Patricia A Cleary
    Diabetes Unit, Massachusetts General Hospital, 32 Fruit St, Boston, MA 02114 2698, USA
    Diabetes 55:3556-65. 2006
    ..Prior intensive diabetes treatment during the DCCT was associated with less atherosclerosis, largely because of reduced levels of A1C during the DCCT...
  51. doi request reprint Abdominal obesity and the spectrum of global cardiometabolic risks in US adults
    H Ghandehari
    Division of Cardiology, Heart Disease Prevention Program, University of California, Irvine, CA 92697, USA
    Int J Obes (Lond) 33:239-48. 2009
    ..To compare the association of obesity and abdominal obesity with cardiometabolic risk factor burden and global estimated coronary heart disease (CHD) risk among multiethnic US adults...
  52. pmc Association of C-reactive protein with reduced forced vital capacity in a nonsmoking U.S. population with metabolic syndrome and diabetes
    Hwa Mu Lee
    1Division of Pulmonary Medicine, Department of Medicine, University of California, Irvine, California, USA
    Diabetes Care 31:2000-2. 2008
    ..We investigated whether high CRP is related to reduced FVC in MetS and diabetes...
  53. doi request reprint Metabolic syndrome, cardiovascular risk and screening for subclinical atherosclerosis
    Shaista Malik
    Division of Cardiology, University of California Irvine Medical Center, 101 City Drive South, Orange, CA 92868, USA
    Expert Rev Cardiovasc Ther 7:273-80. 2009
    ..Early identification could lead to improved patient or physician adherence to risk-reducing behaviors or interventions and improve clinical outcomes...
  54. doi request reprint Prevalence and distribution of sub-clinical atherosclerosis by screening vascular ultrasound in low and intermediate risk adults: the New York physicians study
    John E Postley
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    J Am Soc Echocardiogr 22:1145-51. 2009
    ..The identification of carotid and femoral plaque has been associated with CVD events. In this study, the prevalence of plaques in adults at low and intermediate risk was examined...
  55. ncbi request reprint Relation of coronary calcium progression and control of lipids according to National Cholesterol Education Program guidelines
    Nathan D Wong
    Heart Disease Prevention Program, Department of Medicine, University of California, Irvine, California, USA
    Am J Cardiol 94:431-6. 2004
    ..54). Our findings do not support the use of CAC assessment for monitoring the control of LDL cholesterol, but greater progression of CAC may occur in those in whom HDL cholesterol is not controlled...
  56. ncbi request reprint Prevalence and control of dyslipidemia among persons with diabetes in the United States
    Milagros J Jacobs
    Heart Disease Prevention Program, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
    Diabetes Res Clin Pract 70:263-9. 2005
    ..We assessed the prevalence, treatment, and control of dyslipidemia among United States (U.S.) adults with diabetes...
  57. ncbi request reprint Social network and coronary artery calcification in asymptomatic individuals
    Willem J Kop
    Department of Medical and Clinical Psychology, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
    Psychosom Med 67:343-52. 2005
    ..Psychosocial factors are associated with the development of coronary artery disease. However, studies examining psychosocial factors as risk indicators for coronary artery calcification (CAC) have been inconclusive...
  58. ncbi request reprint Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial
    Karen L Margolis
    HealthPartners Research Foundation PO Box 1524, Mailstop 21111R, Minneapolis, MN 55440 1524, USA
    Hypertension 50:854-61. 2007
    ....
  59. ncbi request reprint Prevalence of and risk factors for subclinical cardiovascular disease in selected US Hispanic ethnic groups: the Multi-Ethnic Study of Atherosclerosis
    Matthew A Allison
    Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093 0811
    Am J Epidemiol 167:962-9. 2008
    ..This finding was also present for the other subclinical CVD measures. These results suggest a differential relationship between risk factors and either prevalence or extent of subclinical disease by Hispanic subgroup...
  60. pmc Association between coronary artery calcification progression and microalbuminuria: the MESA study
    Andrew P DeFilippis
    Division of Cardiology, The Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins University, Baltimore, Maryland, USA
    JACC Cardiovasc Imaging 3:595-604. 2010
    ..This study sought to evaluate the relationship between microalbuminuria (MA) and the development and progression of atherosclerosis, as assessed by incident and progression of coronary artery calcification (CAC)...
  61. doi request reprint Association of FVC and total mortality in US adults with metabolic syndrome and diabetes
    Hwa Mu Lee
    Division of Cardiology, School of Medicine, University of California, Irvine, CA 92697 4101, USA
    Chest 136:171-6. 2009
    ..We investigated whether reduced pulmonary function is associated with increased mortality in persons with these conditions...
  62. pmc Aspirin use, dose, and clinical outcomes in postmenopausal women with stable cardiovascular disease: the Women's Health Initiative Observational Study
    Jeffrey S Berger
    Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Circ Cardiovasc Qual Outcomes 2:78-87. 2009
    ..We sought to evaluate the relationship between aspirin use, dose (81 or 325 mg), and clinical outcomes among postmenopausal women with stable cardiovascular disease (CVD)...
  63. ncbi request reprint Coronary heart disease events preventable by control of blood pressure and lipids in US adults with hypertension
    Victor A Lopez
    Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, CA 92697, USA
    J Clin Hypertens (Greenwich) 9:436-43. 2007
    ..The authors' results demonstrate that combined control of BP and lipid levels may prevent the majority of CHD events in Americans with HTN...
  64. doi request reprint Relationship of thoracic aortic calcium to coronary calcium and its progression (from the Multi-Ethnic Study of Atherosclerosis [MESA])
    Juan J Rivera
    Division of Cardiology, Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins Hospital, Baltimore, Maryland, USA
    Am J Cardiol 103:1562-7. 2009
    ..25 to 30.18). In conclusion, TAC is associated with the incidence and progression of CAC. The detection of TAC may improve risk stratification efforts. Future clinical outcomes studies are needed to support such an approach...
  65. ncbi request reprint Coronary artery calcium scores and risk for cardiovascular events in women classified as "low risk" based on Framingham risk score: the multi-ethnic study of atherosclerosis (MESA)
    Susan G Lakoski
    Department of Internal Medicine Cardiology, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Arch Intern Med 167:2437-42. 2007
    ..Based on population survey data, 95% of American women are considered at low risk based on FRS...
  66. ncbi request reprint Features of the metabolic syndrome and diabetes mellitus as predictors of aortic valve calcification in the Multi-Ethnic Study of Atherosclerosis
    Ronit Katz
    University of Washington, Seattle, WA, USA
    Circulation 113:2113-9. 2006
    ....
  67. ncbi request reprint Age-specific relevance of usual blood pressure to vascular mortality
    Stanley S Franklin
    Lancet 361:1389; author reply 1391-2. 2003
  68. ncbi request reprint Insulin resistance, metabolic syndrome, and subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis (MESA)
    Alain G Bertoni
    Department of Epidemiology and Prevention, Wake Forest University, Winston Salem, North Carolina, USA
    Diabetes Care 30:2951-6. 2007
    ..To investigate the association of insulin resistance and clinically defined metabolic syndrome (MetS) with subclinical atherosclerosis and examine whether these relationships vary by race/ethnicity or sex...
  69. ncbi request reprint Estrogen plus progestin and the risk of coronary heart disease
    JoAnn E Manson
    Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
    N Engl J Med 349:523-34. 2003
    ..In this report, we provide the final results with regard to estrogen plus progestin and CHD from the Women's Health Initiative (WHI)...
  70. pmc Pericardial fat burden on ECG-gated noncontrast CT in asymptomatic patients who subsequently experience adverse cardiovascular events
    Victor Y Cheng
    Department of Imaging, Cedars Sinai Medical Center, Los Angeles, California, USA
    JACC Cardiovasc Imaging 3:352-60. 2010
    ..We aimed to evaluate whether pericardial fat has value in predicting the risk of future adverse cardiovascular outcomes...
  71. ncbi request reprint Predictors of new-onset diastolic and systolic hypertension: the Framingham Heart Study
    Stanley S Franklin
    Heart Disease Prevention Program, University of California, C240 Medical Sciences, Irvine, CA 92697, USA
    Circulation 111:1121-7. 2005
    ..We examined the relations of blood pressure (BP) and clinical risk factors to the new onset of the 3 forms of hypertension...
  72. doi request reprint Low-density lipoprotein and noncalcified coronary plaque composition in patients with newly diagnosed coronary artery disease on computed tomographic angiography
    Victor Y Cheng
    Departments of Internal Medicine and Imaging, Cedars Sinai Medical Center, Los Angeles, California, USA
    Am J Cardiol 105:761-6. 2010
    ....
  73. ncbi request reprint Left ventricular end-systolic stress in young adults: distribution, risk factors, and relation to cardiovascular disease events
    Noel E Santo-Domingo
    Department of Medicine, Division of Cardiology, University of California, Irvine, CA, USA
    Echocardiography 26:1006-11. 2009
    ....
  74. ncbi request reprint The metabolic syndrome in East Asians
    Khiet C Hoang
    Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, CA 92697, USA
    J Cardiometab Syndr 2:276-82. 2007
    ....
  75. doi request reprint Do differences in subclinical cardiovascular disease in mexican americans versus European americans help explain the Hispanic paradox?
    Julius M Gardin
    Division of Cardiology, Department of Medicine, St John Hospital and Medical Center and Wayne State University, Detroit, Michigan, USA
    Am J Cardiol 105:205-9. 2010
    ..Although systolic blood pressure, body surface area, and male gender were most strongly associated with the LV mass, age and diastolic blood pressure, in addition to Mexican-American ethnicity, were the most important indicators of CAC...
  76. ncbi request reprint Baseline achievement of lipid goals and usage of lipid medications in patients with diabetes mellitus (from the Veterans Affairs Diabetes Trial)
    Charles D Meyers
    Novartis Institute for Biomedical Research, Cambridge, Massachusetts, USA
    Am J Cardiol 98:63-5. 2006
    ....
  77. ncbi request reprint Calcified coronary artery plaque measurement with cardiac CT in population-based studies: standardized protocol of Multi-Ethnic Study of Atherosclerosis (MESA) and Coronary Artery Risk Development in Young Adults (CARDIA) study
    J Jeffrey Carr
    Departments of Radiology and Public Health Sciences, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Radiology 234:35-43. 2005
    ....
  78. ncbi request reprint Parental history of stroke and myocardial infarction predicts coronary artery calcification: The Coronary Artery Risk Development in Young Adults (CARDIA) study
    Myriam Fornage
    Institute of Molecular Medicine, University of Texas Health Science Center Houston, Houston, TX 77030, USA
    Eur J Cardiovasc Prev Rehabil 11:421-6. 2004
    ..This study investigates the association between coronary artery calcification (CAC) and parental history of stroke and MI in African-Americans and Caucasians from the CARDIA study...
  79. ncbi request reprint Relation of echocardiographic left ventricular mass, geometry and wall stress, and left atrial dimension to coronary calcium in young adults (the CARDIA study)
    Julius M Gardin
    St John Hospital and Medical Center, Detroit, Michigan, USA
    Am J Cardiol 95:626-9. 2005
    ....
  80. ncbi request reprint Measuring coronary calcium on CT images adjusted for attenuation differences
    Jennifer Clark Nelson
    Center for Health Studies, Group Health Cooperative, Metropolitan Park East, Suite 1600, 1730 Minor Ave, Seattle, WA 98101, USA
    Radiology 235:403-14. 2005
    ..To quantify scanner and participant variability in attenuation values for computed tomographic (CT) images assessed for coronary calcium and define a method for standardizing attenuation values and calibrating calcium measurements...
  81. ncbi request reprint Panic attacks and risk of incident cardiovascular events among postmenopausal women in the Women's Health Initiative Observational Study
    Jordan W Smoller
    Department of Psychiatry, Massachusetts General Hospital, Simches Research Building, 185 Cambridge Street, Boston, MA 02114, USA
    Arch Gen Psychiatry 64:1153-60. 2007
    ..Previous studies have documented an association of depression and phobic anxiety with cardiovascular morbidity and mortality, but little is known about the cardiovascular sequelae of panic anxiety...
  82. ncbi request reprint Concordance of coronary artery calcium estimates between MDCT and electron beam tomography
    Anthony L Daniell
    Department of Imaging, Division of Nuclear Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    AJR Am J Roentgenol 185:1542-5. 2005
    ..The objective of our study was to compare MDCT with electron beam tomography (EBT) for the quantification of coronary artery calcification (CAC)...
  83. ncbi request reprint C-reactive protein for cardiovascular risk assessment in the metabolic syndrome: response to Kholeif et al
    Nathan D Wong
    Diabetes Care 28:2598-9. 2005
  84. ncbi request reprint Depressive symptoms and heart rate variability in postmenopausal women
    Chin K Kim
    Division of Cardiovascular Medicine, University of Florida, Gainesville 32610 0277, USA
    Arch Intern Med 165:1239-44. 2005
    ..Findings regarding a relationship between depressive symptoms and heart rate variability that could explain increased cardiovascular risk have been inconsistent across studies...
  85. ncbi request reprint Race-ethnic differences in the extent, prevalence, and progression of coronary calcium
    Miwa Kawakubo
    Statistical Consultation and Research Center, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, USA
    Ethn Dis 15:198-204. 2005
    ..To compare across four race-ethnic groups the baseline prevalence and extent of coronary calcium and the 7-year rate of progression in the extent of coronary calcium...
  86. pmc A comparison of Chinese traditional and Western medical approaches for the treatment of mild hypertension
    N D Wong
    Department of Medicine, University of California, Irvine 92717
    Yale J Biol Med 64:79-87. 1991
    ..We conclude that Western therapy is more effective in reducing blood pressure as compared with Chinese traditional therapy, but effective control of blood pressure in mild hypertensives is possible with either form of treatment...
  87. doi request reprint Association of blood pressure with left ventricular mass in untreated hypertensives in rural Yunnan Province
    Ashkan Akasheh
    Department of Radiology, School of Medicine, University of California Irvine, Irvine, California, USA
    Am J Hypertens 22:730-4. 2009
    ..HTN is associated with increased left ventricular mass (LVM), but the magnitude and characteristics of this relationship in persons not undergoing treatment are unknown...
  88. pmc Ethnic-specific risks for atherosclerotic calcification of the thoracic and abdominal aorta (from the Multi-Ethnic Study of Atherosclerosis)
    Matthew A Allison
    University of California, San Diego, La Jolla, California, USA
    Am J Cardiol 104:812-7. 2009
    ..In conclusion, compared to whites, African-Americans and Hispanics, but not Chinese, have evidence of less atherosclerosis in the thoracic and abdominal aortas, which does not appear to be accounted for by traditional CVD risk factors...
  89. ncbi request reprint Effect of scanner type on the reproducibility of extracoronary measures of calcification: the multi-ethnic study of atherosclerosis
    Matthew J Budoff
    Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, 1124 W Carson Street, RB2, Torrance, CA 90502, USA
    Acad Radiol 14:1043-9. 2007
    ..Accurate quantification of calcification of the aortic valve, mitral annulus (MAC), and thoracic aortic (TAC) may be possible by using cardiac CT...
  90. pmc Single versus combined blood pressure components and risk for cardiovascular disease: the Framingham Heart Study
    Stanley S Franklin
    Heart Disease Prevention Program, Department of Medicine, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
    Circulation 119:243-50. 2009
    ..We compared systolic BP (SBP) and diastolic BP (DBP) versus pulse pressure (PP) and mean arterial pressure (MAP) combined and each of these 4 BP components alone in predicting CVD events...
  91. pmc Sex hormones, sex hormone binding globulin, and abdominal aortic calcification in women and men in the multi-ethnic study of atherosclerosis (MESA)
    Erin D Michos
    Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD 21287, United States
    Atherosclerosis 200:432-8. 2008
    ..Conflicting findings exist regarding the associations of sex hormones with subclinical atherosclerosis...
  92. ncbi request reprint Implications of estimating coronary heart disease risk in the US population
    Daniel S Berman
    J Am Coll Cardiol 43:1797-8. 2004
  93. ncbi request reprint How important is pulse pressure as a predictor of cardiovascular risk?
    Stanley S Franklin
    Hypertension 39:E12-3. 2002
  94. ncbi request reprint Metabolic syndrome and diabetes are associated with an increased likelihood of inducible myocardial ischemia among patients with subclinical atherosclerosis
    Nathan D Wong
    Director of Cardiac Imaging, Cedars Sinai Medical Center, 8700 Beverly Bldg, Room 1258, Los Angeles, CA 90048, USA
    Diabetes Care 28:1445-50. 2005
    ..Because metabolic syndrome contributes to atherosclerosis, we assessed whether it also influences the relationship between CAC levels and myocardial ischemia...
  95. ncbi request reprint Coronary calcium measurements: effect of CT scanner type and calcium measure on rescan reproducibility--MESA study
    Robert C Detrano
    Div of Cardiology, Los Angeles Biomedical Research Inst, 1124 W Carson St, Bldg E 5, Torrance, CA 90502, USA
    Radiology 236:477-84. 2005
    ..To evaluate the effect of scanner type and calcium measure on the reproducibility of calcium measurements...
  96. ncbi request reprint Computer-aided detection and evaluation of lipid-rich plaque on noncontrast cardiac CT
    Damini Dey
    Department of Imaging, Cedars Sinai Medical Center, 8700 Beverly Blvd, Rm 1258, Los Angeles, CA 90048, USA
    AJR Am J Roentgenol 186:S407-13. 2006
    ..Noncontrast electron beam CT (EBCT) and MDCT are established for the assessment of calcified plaque, but not lipid-rich plaque. We developed software to identify lipid-rich plaque with noncontrast electron beam tomography (EBT) and MDCT...
  97. ncbi request reprint Comparative use of radionuclide stress testing, coronary artery calcium scanning, and noninvasive coronary angiography for diagnostic and prognostic cardiac assessment
    Daniel S Berman
    Department of Imaging and Medicine, Cedars Sinai Medical Center, CSMC Burns and Allen Research Institute, Los Angeles, CA 90048, USA
    Semin Nucl Med 37:2-16. 2007
    ....
  98. ncbi request reprint Family history of premature coronary heart disease and coronary artery calcification: Multi-Ethnic Study of Atherosclerosis (MESA)
    Khurram Nasir
    Cardiac MRI PET CT Program, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    Circulation 116:619-26. 2007
    ....
  99. ncbi request reprint Clinical outcomes after both coronary calcium scanning and exercise myocardial perfusion scintigraphy
    Alan Rozanski
    Department of Medicine, St Luke s Roosevelt Hospital, New York, New York, USA
    J Am Coll Cardiol 49:1352-61. 2007
    ..The purpose of this work was to assess the prognosis in patients undergoing both coronary artery calcium (CAC) scanning and exercise myocardial perfusion scintigraphy (MPS)...
  100. ncbi request reprint 34th Bethesda Conference: Task force #4--How do we select patients for atherosclerosis imaging?
    Peter W F Wilson
    School of Medicine, Boston University, 715 Albany Street, Evans E204, Boston, MA 02118, USA
    J Am Coll Cardiol 41:1898-906. 2003
  101. doi request reprint Molecular imaging for efficacy of pharmacologic intervention in myocardial remodeling
    Susanne W M van den Borne
    Division of Cardiology and Department of Pathology, University of California Irvine School of Medicine, Irvine, CA 92697, USA
    JACC Cardiovasc Imaging 2:187-98. 2009
    ..Using molecular imaging techniques, we examined interstitial alterations during postmyocardial infarction (MI) remodeling and assessed the efficacy of antiangiotensin and antimineralocorticoid intervention, alone and in combination...