Research Topics
| N D WongSummaryAffiliation: University of California Country: USA Publications
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Publications
Screening and risk stratification of patients with the metabolic syndrome and diabetesNathan D Wong
University of California, Heart Disease Prevention Program, C240 Medical Sciences, Irvine, CA 92697, USA
Expert Rev Cardiovasc Ther 4:181-90. 2006..The presence of subclinical atherosclerosis or elevated levels of C-reactive protein can potentially modify recommended treatment goals for lipid and other cardiovascular risk factors...
Metabolic syndrome: cardiovascular risk assessment and managementNathan D Wong
Heart Disease Prevention Program, Department of Medicine, University of California, Irvine, California 92697, USA
Am J Cardiovasc Drugs 7:259-72. 2007....
Metabolic syndrome, diabetes, and incidence and progression of coronary calcium: the Multiethnic Study of Atherosclerosis studyNathan D Wong
Department of Medicine, University of California, Irvine, California 92697 4101, USA
JACC Cardiovasc Imaging 5:358-66. 2012..This study sought to examine and compare the incidence and progression of coronary artery calcium (CAC) among persons with metabolic syndrome (MetS) and diabetes mellitus (DM) versus those with neither condition...
Global cardiovascular risk associated with hypertension and extent of treatment and control according to risk groupNathan D Wong
Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, California, USA
Am J Hypertens 25:561-7. 2012..We examined CVD risk distribution and treatment and control patterns according to risk group...
Global cardiovascular disease risk assessment in United States adults with diabetesNathan D Wong
Heart Disease Prevention Program, Division of Cardiology, University of California, 112 Sprague Hall, Irvine, CA 92697, USA
Diab Vasc Dis Res 9:146-52. 2012..Diabetes mellitus (DM) is often considered a risk equivalent for cardiovascular disease (CVD); however, the variation in CVD risk in adults with DM has not been described...
Do risk factors explain the increased prevalence of type 2 diabetes among California Asian adults?Sarah E Choi
Program in Nursing Science, College of Health Sciences, University of California, Irvine, CA 92697 3959, USA
J Immigr Minor Health 13:803-8. 2011..6-1.75 greater likelihood of DM compared to Caucasians...
Endothelial function and urine albumin levels among asymptomatic Mexican-Americans and non-Hispanic whitesJulius M Gardin
Division of Cardiology, Department of Medicine, St, John Hospital and Medical Center, Detroit, MI 48236, USA
Cardiovasc Ultrasound 6:43. 2008..Our aim was to help explain this apparent paradox by evaluating endothelial function and urine albumin levels in MA and NHW...
Preventing coronary events by optimal control of blood pressure and lipids in patients with the metabolic syndromeNathan D Wong
Heart Disease Prevention Program, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
Am J Cardiol 91:1421-6. 2003..6% for women; control to optimal levels resulted in preventing 80.5% and 82.1% of events, respectively. Thus, many CHD events in patients with MetS may be preventable by nominal or optimal control of lipids and/or blood pressure...
Inadequate control of hypertension in US adults with cardiovascular disease comorbidities in 2003-2004Nathan D Wong
Heart Disease Prevention Program, Department of Medicine, University of California, C240 Medical Sciences, Irvine, CA 92697, USA
Arch Intern Med 167:2431-6. 2007....
Preventing heart disease by controlling hypertension: impact of hypertensive subtype, stage, age, and sexNathan D Wong
Heart Disease Prevention Program, University of California, Irvine, Calif 92697, USA
Am Heart J 145:888-95. 2003..Hypertension is related to significant morbidity and mortality rates from coronary heart disease (CHD). This report examines the relative and absolute impact on risk for CHD by controlling hypertension to high normal and optimal levels...
Intensified screening and treatment of the metabolic syndrome for cardiovascular risk reductionNathan D Wong
Heart Disease Prevention Program, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
Prev Cardiol 8:47-52; quiz 53-4. 2005..Clinicians are recommended to assess MetS in their routine practice and to intensify efforts to adequately treat accompanying lifestyle and clinical risk factors...
Prevalence, treatment, and control of combined hypertension and hypercholesterolemia in the United StatesNathan D Wong
Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, School of Medicine, Irvine, California, USA
Am J Cardiol 98:204-8. 2006..5% to 16%). In conclusion, treatment and control of combined hypertension and hypercholesterolemia are suboptimal. Increased efforts to improve treatment of these conditions are needed...
Abdominal aortic calcium and multi-site atherosclerosis: the Multiethnic Study of AtherosclerosisNathan D Wong
Department of Medicine, University of CA, Irvine, CA 92697 4101, United States
Atherosclerosis 214:436-41. 2011..Abdominal aortic calcification (AAC) is a measure of subclinical cardiovascular disease (CVD). Data are limited regarding its relation to other measures of atherosclerosis...
Surrogate measures of atherosclerosis and implications for evaluating cardiovascular riskNathan D Wong
Heart Disease Prevention Program, University of California, Irvine, CA 92697, USA
Diabetes Obes Metab 5:73-80. 2003
Coronary calcium and cardiovascular event risk: evaluation by age- and sex-specific quartilesNathan D Wong
Heart Disease Prevention Program, University of California, Irvine, CA 92697, USA
Am Heart J 143:456-9. 2002....
Coronary artery calcium evaluation by electron beam computed tomography and its relation to new cardiovascular eventsN D Wong
Division of Cardiology, University of California, Irvine 92697, USA
Am J Cardiol 86:495-8. 2000..5 (p <0.05) and 8.8 (p <0.001), respectively. These data support previous reports showing CAC to be a modest predictor of future cardiovascular events...
Combined association of lipids and blood pressure in relation to incident cardiovascular disease in the elderly: the cardiovascular health studyNathan D Wong
Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, California, USA
Am J Hypertens 23:161-7. 2010..Hypertension and dyslipidemia are highly prevalent in the elderly. We studied the combined impact of both conditions on cardiovascular disease (CVD) events...
Is pulse pressure useful in predicting risk for coronary heart Disease? The Framingham heart studyS S Franklin
Heart Disease Prevention Program, University of California, Irvine, USA
Circulation 100:354-60. 1999..We examined whether PP adds useful information for predicting coronary heart disease (CHD) in the population-based Framingham Heart Study...
Relation of thoracic aortic and aortic valve calcium to coronary artery calcium and risk assessmentNathan D Wong
Heart Disease Prevention Program, Department of Medicine, University of California, Irvine, California, USA
Am J Cardiol 92:951-5. 2003....
Prognostic accuracy of B-natriuretic peptide measurements and coronary artery calcium in asymptomatic subjects (from the Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research [EISNER] study)Leslee J Shaw
Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
Am J Cardiol 104:1245-50. 2009..4% and 35.7% of CV events in patients with hypertension and in elderly patients beyond the Framingham risk score. In conclusion, BNP and CAC are independently predictive of CV events...
Coronary calcium does not accurately predict near-term future coronary events in high-risk adultsR C Detrano
Division of Cardiology, Department of Medicine, Harbor UCLA Medical Center, Torrance, CA 90502 2064, USA
Circulation 99:2633-8. 1999..In addition, we assessed the predictive value of a risk model that included calcium score and cardiac risk-factor data...
Does the relation of blood pressure to coronary heart disease risk change with aging? The Framingham Heart StudyS S Franklin
Preventive Cardiology Program, University of California, Irvine 92697, USA
Circulation 103:1245-9. 2001..We examined the relative importance of diastolic (DBP), systolic (SBP) and pulse pressure (PP) as predictors of coronary heart disease (CHD) risk in different age groups of Framingham Heart Study participants...
Predominance of isolated systolic hypertension among middle-aged and elderly US hypertensives: analysis based on National Health and Nutrition Examination Survey (NHANES) IIIS S Franklin
Heart Disease Prevention Program, University of California, Irvine, CA 92697, USA
Hypertension 37:869-74. 2001..Better awareness of this middle-aged and older high-risk group and more aggressive antihypertensive therapy are necessary to address this treatment gap...
Myeloperoxidase, subclinical atherosclerosis, and cardiovascular disease eventsNathan D Wong
Division of Cardiology, University of California, Irvine, California, USA
JACC Cardiovasc Imaging 2:1093-9. 2009..We evaluated whether myeloperoxidase (MPO) predicts future cardiovascular disease (CVD) events in asymptomatic adults and whether subclinical atherosclerosis may affect this relation...
Cardiovascular disease in U.S. patients with metabolic syndrome, diabetes, and elevated C-reactive proteinShaista Malik
Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
Diabetes Care 28:690-3. 2005..We evaluated whether elevated CRP levels modify the relationship of metabolic syndrome and diabetes with CVD in U.S. adults...
Coronary calcium as a predictor of coronary events in four racial or ethnic groupsRobert Detrano
Department of Radiological Sciences, University of California at Irvine, Irvine, CA 92697, USA
N Engl J Med 358:1336-45. 2008..However, it is not known whether coronary-artery calcium predicts coronary heart disease in other racial or ethnic groups...
Thoracic aortic calcium versus coronary artery calcium for the prediction of coronary heart disease and cardiovascular disease eventsNathan D Wong
Division of Cardiology, University of California, Irvine, California, USA
JACC Cardiovasc Imaging 2:319-26. 2009..This study compared the ability of coronary artery calcium (CAC) and thoracic aortic calcium (TAC) to predict coronary heart disease (CHD) and cardiovascular disease (CVD) events...
The metabolic syndrome, diabetes, and subclinical atherosclerosis assessed by coronary calciumNathan D Wong
Heart Disease Prevention Program, University of California, Irvine, California, USA
J Am Coll Cardiol 41:1547-53. 2003..67 (95% CI 1.12 to 2.50) among those with diabetes, versus those with neither condition. CONCLUSIONS: Those with MetS or diabetes have an increased likelihood of CAC compared with those having neither condition...
Association of combinations of lipid parameters with carotid intima-media thickness and coronary artery calcium in the MESA (Multi-Ethnic Study of Atherosclerosis)Pathmaja Paramsothy
Division of Cardiology, Department of Internal Medicine, University of Washington, Seattle, Washington 98104, USA
J Am Coll Cardiol 56:1034-41. 2010..The purpose of this study was to determine the association of combinations of lipid parameters with subclinical atherosclerosis...
Forced vital capacity paired with Framingham Risk Score for prediction of all-cause mortalityH M Lee
Division of Cardiology, Dept of Medicine, 115 Sprague Hall, University of California, Irvine, CA 92697, USA
Eur Respir J 36:1002-6. 2010..58; p<0.05). Similar results were obtained for FEV(1). Evaluation of lung function may be useful to improve risk stratification in persons with intermediate CHD risk where it adds to prediction of mortality over global risk assessment...
Undertreatment of cardiovascular risk factors among persons with diabetes in the United StatesShaista Malik
Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, CA 92697, USA
Diabetes Res Clin Pract 77:126-33. 2007..We examined the extent of control of cardiovascular risk factors and distance from goal for those with uncontrolled levels in a recent sample of U.S. adults with diabetes...
Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adultsShaista Malik
Heart Disease Prevention Program, University of California, Irvine 92697, USA
Circulation 110:1245-50. 2004..Moreover, MetS more strongly predicts CHD, CVD, and total mortality than its individual components. CONCLUSIONS: CHD, CVD, and total mortality are significantly higher in US adults with than in those without MetS...
Value of coronary artery calcium scanning by computed tomography for predicting coronary heart disease in diabetic subjectsWenchun Qu
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Diabetes Care 26:905-10. 2003..01), but not in diabetic subjects (RR <or= 1.7, P > 0.05). CONCLUSIONS: The risk of coronary heart disease increases with increasing calcium scores and diabetes status. Calcium scores have less prognostic value in diabetic subjects...
Cardiovascular comorbidities and blood pressure control in stroke survivorsManoj Kesarwani
Heart Disease Prevention Program, Division of Cardiology, Department ofMedicine, University of California, Irvine, California 92697 4101, USA
J Hypertens 27:1056-63. 2009..To examine the association of cardiovascular(CV) comorbidities with the likelihood of being a stroke survivor and to determine the prevalence, treatment, and control of hypertension in this population...
Prevalence and extent of dyslipidemia and recommended lipid levels in US adults with and without cardiovascular comorbidities: the National Health and Nutrition Examination Survey 2003-2004Heli Ghandehari
Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, CA 92697, USA
Am Heart J 156:112-9. 2008..We evaluated the proportion of US adults with and without these conditions at (and distance to) recommended levels of LDL-C, non-high-density lipoprotein cholesterol (non-HDL-C), HDL-C, and triglycerides...
Comparison of atherosclerotic calcification burden in persons with the cardiometabolic syndrome and diabetesNathan D Wong
Department of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
J Cardiometab Syndr 1:90-4. 2006..52-2.90) for CAC and 1.14 (0.91-1.42), 1.03 (0.77-1.37), 1.03 (0.68-1.54), and 1.41 (1.03-1.92) for TAC. Multiple CMS risk factors are associated with increased CAC, but not TAC; DM with CMS has the highest prevalence of CAC and TAC...
Metabolic and clinical outcomes in nondiabetic individuals with the metabolic syndrome assigned to chlorthalidone, amlodipine, or lisinopril as initial treatment for hypertension: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Henry R Black
New York University School of Medicine, New York, New York, USA
Diabetes Care 31:353-60. 2008..Optimal initial antihypertensive drug therapy in people with the metabolic syndrome is unknown...
M-mode echocardiographic predictors of six- to seven-year incidence of coronary heart disease, stroke, congestive heart failure, and mortality in an elderly cohort (the Cardiovascular Health Study)J M Gardin
Division of Cardiology, Department of Medicine, University of California, Irvine, California, USA
Am J Cardiol 87:1051-7. 2001....
Left ventricular mass in the elderly. The Cardiovascular Health StudyJ M Gardin
Department of Medicine, University of California, Irvine, USA
Hypertension 29:1095-103. 1997....
Blood pressure categories, hypertensive subtypes, and the metabolic syndromeStanley S Franklin
Heart Disease Prevention Program, University of California, Irvine, California 92697, USA
J Hypertens 24:2009-16. 2006..Elevated blood pressure (BP) is one element of metabolic syndrome (MetS); however, the relation of various BP categories and hypertension subtypes to the likelihood of having MetS is not well defined...
Impact of C-reactive protein on the likelihood of peripheral arterial disease in United States adults with the metabolic syndrome, diabetes mellitus, and preexisting cardiovascular diseaseJohn D Vu
Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, School of Medicine, Irvine, California, USA
Am J Cardiol 96:655-8. 2005..6, 95% confidence interval 2.2 to 34.0, p = 0.001). In conclusion, the likelihood of PAD in US adults with MS and DM is enhanced by elevated CRP levels...
Risk factor differences for aortic versus coronary calcified atherosclerosis: the multiethnic study of atherosclerosisMichael H Criqui
Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093 0607, USA
Arterioscler Thromb Vasc Biol 30:2289-96. 2010..The goal of this study was to compare and contrast coronary artery calcium (CAC) with abdominal aortic calcium (AAC) in terms of their associations with traditional and novel cardiovascular disease (CVD) risk factors...
Measures of coronary artery calcification and association with the metabolic syndrome and diabetesUzoma N Ibebuogu
Division of Cardiology, Medical College of Georgia, Augusta, GA, USA
J Cardiometab Syndr 4:6-11. 2009..In addition, the presence of the metabolic syndrome or DM with increased FRS has incremental value over the FRS, DM, or the metabolic syndrome alone in predicting significant CAC...
Global coronary heart disease risk assessment of individuals with the metabolic syndrome in the U.SKhiet C Hoang
Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, California, USA
Diabetes Care 31:1405-9. 2008..This study describes the distribution of 10-year CHD risk among U.S. adults with metabolic syndrome...
The effect of intensive glycemic treatment on coronary artery calcification in type 1 diabetic participants of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) StudyPatricia A Cleary
Diabetes Unit, Massachusetts General Hospital, 32 Fruit St, Boston, MA 02114-2698, USA
Diabetes 55:3556-65. 2006..Prior intensive diabetes treatment during the DCCT was associated with less atherosclerosis, largely because of reduced levels of A1C during the DCCT...
Characteristics and lipid distribution of a large, high-risk, hypertensive population: the lipid-lowering component of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)Vasilios Papademetriou
Veterans Affairs Medical Center, Washington, DC 20422, USA
J Clin Hypertens (Greenwich) 5:377-84. 2003..The success of the randomization of this large, diverse population and the differences in the lipid distributions among its subgroups will allow further understanding of optimal lipid-lowering treatment...
Abdominal obesity and the spectrum of global cardiometabolic risks in US adultsH Ghandehari
Division of Cardiology, Heart Disease Prevention Program, University of California, Irvine, CA 92697, USA
Int J Obes (Lond) 33:239-48. 2009..To compare the association of obesity and abdominal obesity with cardiometabolic risk factor burden and global estimated coronary heart disease (CHD) risk among multiethnic US adults...
Association of C-reactive protein with reduced forced vital capacity in a nonsmoking U.S. population with metabolic syndrome and diabetesHwa Mu Lee
1Division of Pulmonary Medicine, Department of Medicine, University of California, Irvine, California, USA
Diabetes Care 31:2000-2. 2008..We investigated whether high CRP is related to reduced FVC in MetS and diabetes...
Metabolic syndrome, cardiovascular risk and screening for subclinical atherosclerosisShaista Malik
Division of Cardiology, University of California Irvine Medical Center, 101 City Drive South, Orange, CA 92868, USA
Expert Rev Cardiovasc Ther 7:273-80. 2009..Early identification could lead to improved patient or physician adherence to risk-reducing behaviors or interventions and improve clinical outcomes...
Prevalence and distribution of sub-clinical atherosclerosis by screening vascular ultrasound in low and intermediate risk adults: the New York physicians studyJohn E Postley
Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA
J Am Soc Echocardiogr 22:1145-51. 2009..The identification of carotid and femoral plaque has been associated with CVD events. In this study, the prevalence of plaques in adults at low and intermediate risk was examined...
Relation of coronary calcium progression and control of lipids according to National Cholesterol Education Program guidelinesNathan D Wong
Heart Disease Prevention Program, Department of Medicine, University of California, Irvine, California, USA
Am J Cardiol 94:431-6. 2004..54). Our findings do not support the use of CAC assessment for monitoring the control of LDL cholesterol, but greater progression of CAC may occur in those in whom HDL cholesterol is not controlled...
Prevalence and control of dyslipidemia among persons with diabetes in the United StatesMilagros J Jacobs
Heart Disease Prevention Program, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
Diabetes Res Clin Pract 70:263-9. 2005..CONCLUSION: Many persons with diabetes remain uncontrolled for dyslipidemia. Intensified efforts at screening and treatment according to current guidelines are warranted...
Social network and coronary artery calcification in asymptomatic individualsWillem J Kop
Department of Medical and Clinical Psychology, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
Psychosom Med 67:343-52. 2005..Psychosocial factors are associated with the development of coronary artery disease. However, studies examining psychosocial factors as risk indicators for coronary artery calcification (CAC) have been inconclusive...
Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trialKaren L Margolis
HealthPartners Research Foundation PO Box 1524, Mailstop 21111R, Minneapolis, MN 55440 1524, USA
Hypertension 50:854-61. 2007....
Relationship of thoracic aortic calcium to coronary calcium and its progression (from the Multi-Ethnic Study of Atherosclerosis [MESA])Juan J Rivera
Division of Cardiology, Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins Hospital, Baltimore, Maryland, USA
Am J Cardiol 103:1562-7. 2009..25 to 30.18). In conclusion, TAC is associated with the incidence and progression of CAC. The detection of TAC may improve risk stratification efforts. Future clinical outcomes studies are needed to support such an approach...
Prevalence of and risk factors for subclinical cardiovascular disease in selected US Hispanic ethnic groups: the Multi-Ethnic Study of AtherosclerosisMatthew A Allison
Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093 0811
Am J Epidemiol 167:962-9. 2008..This finding was also present for the other subclinical CVD measures. These results suggest a differential relationship between risk factors and either prevalence or extent of subclinical disease by Hispanic subgroup...
Coronary heart disease events preventable by control of blood pressure and lipids in US adults with hypertensionVictor A Lopez
Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, CA 92697, USA
J Clin Hypertens (Greenwich) 9:436-43. 2007..The authors' results demonstrate that combined control of BP and lipid levels may prevent the majority of CHD events in Americans with HTN...
Association between coronary artery calcification progression and microalbuminuria: the MESA studyAndrew P DeFilippis
Division of Cardiology, The Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins University, Baltimore, Maryland, USA
JACC Cardiovasc Imaging 3:595-604. 2010..This study sought to evaluate the relationship between microalbuminuria (MA) and the development and progression of atherosclerosis, as assessed by incident and progression of coronary artery calcification (CAC)...
Aspirin use, dose, and clinical outcomes in postmenopausal women with stable cardiovascular disease: the Women's Health Initiative Observational StudyJeffrey S Berger
Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Circ Cardiovasc Qual Outcomes 2:78-87. 2009..We sought to evaluate the relationship between aspirin use, dose (81 or 325 mg), and clinical outcomes among postmenopausal women with stable cardiovascular disease (CVD)...
Association of FVC and total mortality in US adults with metabolic syndrome and diabetesHwa Mu Lee
Division of Cardiology, School of Medicine, University of California, Irvine, CA 92697 4101, USA
Chest 136:171-6. 2009..We investigated whether reduced pulmonary function is associated with increased mortality in persons with these conditions...
Age-specific relevance of usual blood pressure to vascular mortalityStanley S Franklin
Lancet 361:1389; author reply 1391-2. 2003
Insulin resistance, metabolic syndrome, and subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis (MESA)Alain G Bertoni
Department of Epidemiology and Prevention, Wake Forest University, Winston Salem, North Carolina, USA
Diabetes Care 30:2951-6. 2007..To investigate the association of insulin resistance and clinically defined metabolic syndrome (MetS) with subclinical atherosclerosis and examine whether these relationships vary by race/ethnicity or sex...
Features of the metabolic syndrome and diabetes mellitus as predictors of aortic valve calcification in the Multi-Ethnic Study of AtherosclerosisRonit Katz
University of Washington, Seattle, WA, USA
Circulation 113:2113-9. 2006..CONCLUSIONS: In the MESA cohort, the metabolic syndrome and diabetes mellitus are associated with increased risk of AVC, and AVC prevalence is increased with increasing number of metabolic syndrome components...
Estrogen plus progestin and the risk of coronary heart diseaseJoAnn E Manson
Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
N Engl J Med 349:523-34. 2003..In this report, we provide the final results with regard to estrogen plus progestin and CHD from the Women's Health Initiative (WHI)...
Coronary artery calcium scores and risk for cardiovascular events in women classified as "low risk" based on Framingham risk score: the multi-ethnic study of atherosclerosis (MESA)Susan G Lakoski
Department of Internal Medicine Cardiology, Medical Center Boulevard, Winston Salem, NC 27157, USA
Arch Intern Med 167:2437-42. 2007..Based on population survey data, 95% of American women are considered at low risk based on FRS...
Pericardial fat burden on ECG-gated noncontrast CT in asymptomatic patients who subsequently experience adverse cardiovascular eventsVictor Y Cheng
Department of Imaging, Cedars Sinai Medical Center, Los Angeles, California, USA
JACC Cardiovasc Imaging 3:352-60. 2010..We aimed to evaluate whether pericardial fat has value in predicting the risk of future adverse cardiovascular outcomes...
Predictors of new-onset diastolic and systolic hypertension: the Framingham Heart StudyStanley S Franklin
Heart Disease Prevention Program, University of California, C240 Medical Sciences, Irvine, CA 92697, USA
Circulation 111:1121-7. 2005..We examined the relations of blood pressure (BP) and clinical risk factors to the new onset of the 3 forms of hypertension...
Left ventricular end-systolic stress in young adults: distribution, risk factors, and relation to cardiovascular disease eventsNoel E Santo-Domingo
Department of Medicine, Division of Cardiology, University of California, Irvine, CA, USA
Echocardiography 26:1006-11. 2009....
Do differences in subclinical cardiovascular disease in mexican americans versus European americans help explain the Hispanic paradox?Julius M Gardin
Division of Cardiology, Department of Medicine, St John Hospital and Medical Center and Wayne State University, Detroit, Michigan, USA
Am J Cardiol 105:205-9. 2010..Although systolic blood pressure, body surface area, and male gender were most strongly associated with the LV mass, age and diastolic blood pressure, in addition to Mexican-American ethnicity, were the most important indicators of CAC...
Low-density lipoprotein and noncalcified coronary plaque composition in patients with newly diagnosed coronary artery disease on computed tomographic angiographyVictor Y Cheng
Departments of Internal Medicine and Imaging, Cedars Sinai Medical Center, Los Angeles, California, USA
Am J Cardiol 105:761-6. 2010....
The metabolic syndrome in East AsiansKhiet C Hoang
Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, CA 92697, USA
J Cardiometab Syndr 2:276-82. 2007....
Parental history of stroke and myocardial infarction predicts coronary artery calcification: The Coronary Artery Risk Development in Young Adults (CARDIA) studyMyriam Fornage
Institute of Molecular Medicine, University of Texas Health Science Center Houston, Houston, TX 77030, USA
Eur J Cardiovasc Prev Rehabil 11:421-6. 2004..This study investigates the association between coronary artery calcification (CAC) and parental history of stroke and MI in African-Americans and Caucasians from the CARDIA study...
Depressive symptoms and heart rate variability in postmenopausal womenChin K Kim
Division of Cardiovascular Medicine, University of Florida, Gainesville 32610-0277, USA
Arch Intern Med 165:1239-44. 2005..These findings may contribute to the increased cardiac morbidity and mortality rates associated with depression in other studies...
C-reactive protein for cardiovascular risk assessment in the metabolic syndrome: response to Kholeif et alNathan D Wong
Diabetes Care 28:2598-9. 2005
Measuring coronary calcium on CT images adjusted for attenuation differencesJennifer Clark Nelson
Center for Health Studies, Group Health Cooperative, Metropolitan Park East, Suite 1600, 1730 Minor Ave, Seattle, WA 98101, USA
Radiology 235:403-14. 2005..To quantify scanner and participant variability in attenuation values for computed tomographic (CT) images assessed for coronary calcium and define a method for standardizing attenuation values and calibrating calcium measurements...
Race-ethnic differences in the extent, prevalence, and progression of coronary calciumMiwa Kawakubo
Statistical Consultation and Research Center, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, USA
Ethn Dis 15:198-204. 2005..The relationship between calcification and the incidence of coronary heart disease in these race-ethnic groups needs further exploration...
Relation of echocardiographic left ventricular mass, geometry and wall stress, and left atrial dimension to coronary calcium in young adults (the CARDIA study)Julius M Gardin
St. John Hospital and Medical Center, Detroit, Michigan, USA
Am J Cardiol 95:626-9. 2005....
Calcified coronary artery plaque measurement with cardiac CT in population-based studies: standardized protocol of Multi-Ethnic Study of Atherosclerosis (MESA) and Coronary Artery Risk Development in Young Adults (CARDIA) studyJ Jeffrey Carr
Departments of Radiology and Public Health Sciences, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA
Radiology 234:35-43. 2005....
Baseline achievement of lipid goals and usage of lipid medications in patients with diabetes mellitus (from the Veterans Affairs Diabetes Trial)Charles D Meyers
Novartis Institute for Biomedical Research, Cambridge, Massachusetts, USA
Am J Cardiol 98:63-5. 2006....
Concordance of coronary artery calcium estimates between MDCT and electron beam tomographyAnthony L Daniell
Department of Imaging, Division of Nuclear Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
AJR Am J Roentgenol 185:1542-5. 2005..4 mm3 for the volume score. CONCLUSION: Differences in CAC measurements using EBT and MDCT are similar to interscan differences in CAC measurements previously reported for EBT or for other MDCT scanners individually...
Panic attacks and risk of incident cardiovascular events among postmenopausal women in the Women's Health Initiative Observational StudyJordan W Smoller
Department of Psychiatry, Massachusetts General Hospital, Simches Research Building, 185 Cambridge Street, Boston, MA 02114, USA
Arch Gen Psychiatry 64:1153-60. 2007..Previous studies have documented an association of depression and phobic anxiety with cardiovascular morbidity and mortality, but little is known about the cardiovascular sequelae of panic anxiety...
A comparison of Chinese traditional and Western medical approaches for the treatment of mild hypertensionN D Wong
Department of Medicine, University of California, Irvine 92717
Yale J Biol Med 64:79-87. 1991..We conclude that Western therapy is more effective in reducing blood pressure as compared with Chinese traditional therapy, but effective control of blood pressure in mild hypertensives is possible with either form of treatment...
Effect of scanner type on the reproducibility of extracoronary measures of calcification: the multi-ethnic study of atherosclerosisMatthew J Budoff
Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, 1124 W Carson Street, RB2, Torrance, CA 90502, USA
Acad Radiol 14:1043-9. 2007..Accurate quantification of calcification of the aortic valve, mitral annulus (MAC), and thoracic aortic (TAC) may be possible by using cardiac CT...
Association of blood pressure with left ventricular mass in untreated hypertensives in rural Yunnan ProvinceAshkan Akasheh
Department of Radiology, School of Medicine, University of California Irvine, Irvine, California, USA
Am J Hypertens 22:730-4. 2009..HTN is associated with increased left ventricular mass (LVM), but the magnitude and characteristics of this relationship in persons not undergoing treatment are unknown...
Single versus combined blood pressure components and risk for cardiovascular disease: the Framingham Heart StudyStanley S Franklin
Heart Disease Prevention Program, Department of Medicine, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
Circulation 119:243-50. 2009..We compared systolic BP (SBP) and diastolic BP (DBP) versus pulse pressure (PP) and mean arterial pressure (MAP) combined and each of these 4 BP components alone in predicting CVD events...
Ethnic-specific risks for atherosclerotic calcification of the thoracic and abdominal aorta (from the Multi-Ethnic Study of Atherosclerosis)Matthew A Allison
University of California, San Diego, La Jolla, California, USA
Am J Cardiol 104:812-7. 2009..In conclusion, compared to whites, African-Americans and Hispanics, but not Chinese, have evidence of less atherosclerosis in the thoracic and abdominal aortas, which does not appear to be accounted for by traditional CVD risk factors...
Sex hormones, sex hormone binding globulin, and abdominal aortic calcification in women and men in the multi-ethnic study of atherosclerosis (MESA)Erin D Michos
Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD 21287, United States
Atherosclerosis 200:432-8. 2008..Conflicting findings exist regarding the associations of sex hormones with subclinical atherosclerosis...
Metabolic syndrome and diabetes are associated with an increased likelihood of inducible myocardial ischemia among patients with subclinical atherosclerosisNathan D Wong
Director of Cardiac Imaging, Cedars-Sinai Medical Center, 8700 Beverly Bldg, Room 1258, Los Angeles, CA 90048, USA
Diabetes Care 28:1445-50. 2005..These findings suggest the need for assessment of metabolic status when interpreting the results of CAC imaging among patients undergoing such testing because of suspected CAD...
Comparative use of radionuclide stress testing, coronary artery calcium scanning, and noninvasive coronary angiography for diagnostic and prognostic cardiac assessmentDaniel S Berman
Department of Imaging and Medicine, Cedars Sinai Medical Center, CSMC Burns and Allen Research Institute, Los Angeles, CA 90048, USA
Semin Nucl Med 37:2-16. 2007....
How important is pulse pressure as a predictor of cardiovascular risk?Stanley S Franklin
Hypertension 39:E12-3. 2002
Computer-aided detection and evaluation of lipid-rich plaque on noncontrast cardiac CTDamini Dey
Department of Imaging, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Rm. 1258, Los Angeles, CA 90048, USA
AJR Am J Roentgenol 186:S407-13. 2006..1 +/- 3.6 H, respectively. In five patients, the locations of lipid-rich plaque correlated well with available intravascular sonography findings. CONCLUSION: Our method may be able to identify lipid-rich plaque on noncontrast cardiac CT...
Family history of premature coronary heart disease and coronary artery calcification: Multi-Ethnic Study of Atherosclerosis (MESA)Khurram Nasir
Cardiac MRI PET CT Program, Massachusetts General Hospital, Harvard Medical School, Boston, USA
Circulation 116:619-26. 2007....
Coronary calcium measurements: effect of CT scanner type and calcium measure on rescan reproducibility--MESA studyRobert C Detrano
Div of Cardiology, Los Angeles Biomedical Research Inst, 1124 W Carson St, Bldg E 5, Torrance, CA 90502, USA
Radiology 236:477-84. 2005..To evaluate the effect of scanner type and calcium measure on the reproducibility of calcium measurements...
Implications of estimating coronary heart disease risk in the US populationDaniel S Berman
J Am Coll Cardiol 43:1797-8. 2004
Impact of subclinical atherosclerosis on cardiovascular disease events in individuals with metabolic syndrome and diabetes: the multi-ethnic study of atherosclerosisShaista Malik
Heart Disease Prevention Program, Division of Cardiology, University of California Irvine, Irvine, California, USA
Diabetes Care 34:2285-90. 2011..We evaluated whether screening for coronary artery calcium (CAC) and carotid intimal-medial thickness (CIMT) can improve CVD risk stratification over traditional risk factors (RFs) in people with MetS and diabetes...
34th Bethesda Conference: Task force #4--How do we select patients for atherosclerosis imaging?Peter W F Wilson
School of Medicine, Boston University, 715 Albany Street, Evans E204, Boston, MA 02118, USA
J Am Coll Cardiol 41:1898-906. 2003
Molecular imaging for efficacy of pharmacologic intervention in myocardial remodelingSusanne W M van den Borne
Division of Cardiology and Department of Pathology, University of California Irvine School of Medicine, Irvine, CA 92697, USA
JACC Cardiovasc Imaging 2:187-98. 2009..Using molecular imaging techniques, we examined interstitial alterations during postmyocardial infarction (MI) remodeling and assessed the efficacy of antiangiotensin and antimineralocorticoid intervention, alone and in combination...
Reproducibility of coronary artery calcified plaque with cardiac 64-MDCT: the Multi-Ethnic Study of AtherosclerosisMatthew Jay Budoff
Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, 1124 W Carson St, RB2, Torrance, CA 90502, USA
AJR Am J Roentgenol 192:613-7. 2009..The aim of this study was to compare the interscan variability for both Agatston and volume scores derived with newer (16- and 64-MDCT) scanners with that derived with older scanners in the Multi-Ethnic Study of Atherosclerosis...
Clinical outcomes after both coronary calcium scanning and exercise myocardial perfusion scintigraphyAlan Rozanski
Department of Medicine, St Luke s Roosevelt Hospital, New York, New York, USA
J Am Coll Cardiol 49:1352-61. 2007..The purpose of this work was to assess the prognosis in patients undergoing both coronary artery calcium (CAC) scanning and exercise myocardial perfusion scintigraphy (MPS)...
Polymorphism of the soluble epoxide hydrolase is associated with coronary artery calcification in African-American subjects: The Coronary Artery Risk Development in Young Adults (CARDIA) studyMyriam Fornage
Institute of Molecular Medicine, University of Texas Health Science Center, Houston, 2121 W Holcombe Blvd, Houston, TX 77030, USA
Circulation 109:335-9. 2004..We examined the relationship between a common, functional polymorphism of the human sEH gene and coronary artery calcification (CAC) in young, largely asymptomatic African-American and non-Hispanic white subjects...
History of depression, race, and cardiovascular risk in CARDIASarah Knox
Division of Epidemiology, Statistics and Prevention, National Institute of Child Health and Human Development, Bethesda, Maryland 20892 7510, USA
Int J Behav Med 13:44-50. 2006..These data indicate that in this still healthy cohort, there are already associations between depression and factors that predispose to cardiovascular risk...
