Paul Wolters

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Parasitic infection improves survival from septic peritonitis by enhancing mast cell responses to bacteria in mice
    Rachel E Sutherland
    Department of Medicine, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 6:e27564. 2011
  2. pmc Pathogenesis of idiopathic pulmonary fibrosis
    Paul J Wolters
    Department of Medicine, School of Medicine, University of California, San Francisco, California 94143 email
    Annu Rev Pathol 9:157-79. 2014
  3. pmc Cleaved cytokeratin-18 is a mechanistically informative biomarker in idiopathic pulmonary fibrosis
    Seung Ick Cha
    Department of Medicine, University of California, San Francisco School of Medicine, San Francisco, CA 94143 0111, USA
    Respir Res 13:105. 2012
  4. ncbi request reprint Clinical problem-solving. Anchors away
    Carolyn S Calfee
    Department of Medicine, University of California, San Francisco, USA
    N Engl J Med 356:504-9. 2007
  5. pmc Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β
    Hideya Kitamura
    Department of Pathology, UCSF, San Francisco, California, USA
    J Clin Invest 121:2863-75. 2011
  6. pmc Systemic mast cell degranulation increases mortality during polymicrobial septic peritonitis in mice
    Eric J Seeley
    Department of Medicine, University of California, San Francisco, CA, USA
    J Leukoc Biol 90:591-7. 2011
  7. pmc Alveolar epithelial cells express mesenchymal proteins in patients with idiopathic pulmonary fibrosis
    Cecilia Marmai
    Department of Medicine and Cardiovascular Research Institute, University of California, San Francisco, California 94143 0111, USA
    Am J Physiol Lung Cell Mol Physiol 301:L71-8. 2011
  8. pmc Mast cell IL-6 improves survival from Klebsiella pneumonia and sepsis by enhancing neutrophil killing
    Rachel E Sutherland
    Department of Medicine and the Cardiovascular Research Institute, University of California, San Francisco, CA 94143, USA
    J Immunol 181:5598-605. 2008
  9. ncbi request reprint Relationships between early inflammatory response to bleomycin and sensitivity to lung fibrosis: a role for dipeptidyl-peptidase I and tissue inhibitor of metalloproteinase-3?
    Nicolas Pottier
    IPMC, CNRS UMR6097, 660, route des Lucioles, F06560 Sophia Antipolis, France
    Am J Respir Crit Care Med 176:1098-107. 2007
  10. pmc Idiopathic nonspecific interstitial pneumonia: lung manifestation of undifferentiated connective tissue disease?
    Brent W Kinder
    Department of Medicine, University of California School of Medicine, San Francisco, California, USA
    Am J Respir Crit Care Med 176:691-7. 2007

Research Grants

  1. Mast Cells and the Host Response in the Lung
    Paul Wolters; Fiscal Year: 2004
  2. MAST CELL CYSTEINE PROTEASES IN LUNG INFLAMMATION
    Paul Wolters; Fiscal Year: 2003
  3. Mast Cells and the Host Response in the Lung
    Paul Wolters; Fiscal Year: 2005
  4. Mast Cells and the Host Response in the Lung
    Paul Wolters; Fiscal Year: 2006
  5. Mast Cells and the Host Response in the Lung
    Paul Wolters; Fiscal Year: 2007

Collaborators

  • Jack Gauldie
  • George H Caughey
  • Kirk D Jones
  • Harold R Collard
  • T E King
  • Harold A Chapman
  • Sam Hawgood
  • Brent Kinder
  • C S Calfee
  • Rachel E Sutherland
  • Xiang Xu
  • Sophia S Kim
  • Eric J Seeley
  • Seung Ick Cha
  • Cecilia Marmai
  • Hideya Kitamura
  • Gregory M Dolganov
  • Nicolas Pottier
  • DongJi Zhang
  • Nigel P Killeen
  • Bing Wang
  • Samuel T Edwards
  • Joyce S Lee
  • Christopher J Ryerson
  • Feroz R Papa
  • Brett M Elicker
  • Sophia S Barry
  • Jasleen Kukreja
  • Dong Soon Kim
  • Jean Publicover
  • James D Marks
  • Amanda Goodsell
  • David Jablons
  • Louis Reichardt
  • Xiaohui Fang
  • Sangeeta Somanath
  • Jennifer Markovics
  • Michael A Matthay
  • Arthur Hill
  • Shuwei Jiang
  • Tyren Barker
  • Shunsuke Minagawa
  • Jody Lynn Baron
  • Kevin K Kim
  • Jeffery A Golden
  • Charles W Hoopes
  • Stephanie Cambier
  • Jianlong Lou
  • Jean Francois Pittet
  • Stephen L Nishimura
  • Andrew McKinstry
  • Joanna S Olsen
  • S Armando Villalta
  • Pascal Barbry
  • Virginie Defamie
  • Francis Gauthier
  • Rachel Sutherland
  • Bruno Cardinaud
  • Bernard Mari
  • Cécile Chupin
  • Géraldine Rios
  • Yves Berthiaume
  • Min Yang
  • Donald M McDonald
  • Peter Baluk
  • Brandon M Sullivan
  • Richard Riese
  • Richard Bucala
  • Natalya Lyubynska
  • Richard M Locksley
  • Jiusong Sun
  • Hong Zhang
  • Shiro Kitamoto
  • John R David
  • Xiaozhu Huang
  • Patricia W Finn
  • Clifford A Lowell
  • Guo Ping Shi
  • Lin Leng
  • Kenneth C Fang
  • Anthony C Cruz
  • Charles Hoopes
  • Samantha Donnelly
  • Edward S Schulman
  • Paul F Dazin

Detail Information

Publications14

  1. pmc Parasitic infection improves survival from septic peritonitis by enhancing mast cell responses to bacteria in mice
    Rachel E Sutherland
    Department of Medicine, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 6:e27564. 2011
    ....
  2. pmc Pathogenesis of idiopathic pulmonary fibrosis
    Paul J Wolters
    Department of Medicine, School of Medicine, University of California, San Francisco, California 94143 email
    Annu Rev Pathol 9:157-79. 2014
    ..We then discuss the pathologic changes within IPF fibroblasts and the extracellular matrix, and we conclude with a summary of how these profibrotic pathways may be interrelated. ..
  3. pmc Cleaved cytokeratin-18 is a mechanistically informative biomarker in idiopathic pulmonary fibrosis
    Seung Ick Cha
    Department of Medicine, University of California, San Francisco School of Medicine, San Francisco, CA 94143 0111, USA
    Respir Res 13:105. 2012
    ....
  4. ncbi request reprint Clinical problem-solving. Anchors away
    Carolyn S Calfee
    Department of Medicine, University of California, San Francisco, USA
    N Engl J Med 356:504-9. 2007
  5. pmc Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β
    Hideya Kitamura
    Department of Pathology, UCSF, San Francisco, California, USA
    J Clin Invest 121:2863-75. 2011
    ..Our data therefore indicate that fibroblasts have a crucial role in regulating both fibrotic and immune responses in the lung...
  6. pmc Systemic mast cell degranulation increases mortality during polymicrobial septic peritonitis in mice
    Eric J Seeley
    Department of Medicine, University of California, San Francisco, CA, USA
    J Leukoc Biol 90:591-7. 2011
    ..These results indicate that in contrast to the benefits of local MC activation during infection, systemic MC activation worsens survival during CLP-induced sepsis...
  7. pmc Alveolar epithelial cells express mesenchymal proteins in patients with idiopathic pulmonary fibrosis
    Cecilia Marmai
    Department of Medicine and Cardiovascular Research Institute, University of California, San Francisco, California 94143 0111, USA
    Am J Physiol Lung Cell Mol Physiol 301:L71-8. 2011
    ..These data suggest that alveolar type II cells can acquire features of mesenchymal cells in IPF lungs and that TGF-β can mediate this process...
  8. pmc Mast cell IL-6 improves survival from Klebsiella pneumonia and sepsis by enhancing neutrophil killing
    Rachel E Sutherland
    Department of Medicine and the Cardiovascular Research Institute, University of California, San Francisco, CA 94143, USA
    J Immunol 181:5598-605. 2008
    ..These results establish that mast cell IL-6 is a critical mediator of survival following K. pneumoniae infection and sepsis and suggest that IL-6 protects from death by augmenting neutrophil killing of bacteria...
  9. ncbi request reprint Relationships between early inflammatory response to bleomycin and sensitivity to lung fibrosis: a role for dipeptidyl-peptidase I and tissue inhibitor of metalloproteinase-3?
    Nicolas Pottier
    IPMC, CNRS UMR6097, 660, route des Lucioles, F06560 Sophia Antipolis, France
    Am J Respir Crit Care Med 176:1098-107. 2007
    ..Different sensitivities to profibrotic compounds such as bleomycin are observed among mouse strains...
  10. pmc Idiopathic nonspecific interstitial pneumonia: lung manifestation of undifferentiated connective tissue disease?
    Brent W Kinder
    Department of Medicine, University of California School of Medicine, San Francisco, California, USA
    Am J Respir Crit Care Med 176:691-7. 2007
    ....
  11. pmc Neutrophil histamine contributes to inflammation in mycoplasma pneumonia
    Xiang Xu
    Cardiovascular Research Institute, Department of Microbiology Immunology, University of California at San Francisco, and Veterans Affairs Medical Center, San Francisco 94121, USA
    J Exp Med 203:2907-17. 2006
    ..These findings suggest that neutrophils, provoked by mycoplasma, greatly expand their capacity to synthesize histamine, thereby contributing to lung and airway inflammation...
  12. ncbi request reprint Cutting edge: Deficiency of macrophage migration inhibitory factor impairs murine airway allergic responses
    Bing Wang
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 77th Avenue Louis Pasteur, Boston, MA 02115, USA
    J Immunol 177:5779-84. 2006
    ....
  13. pmc Mast cells protect mice from Mycoplasma pneumonia
    Xiang Xu
    Pulmonary and Critical Care Medicine, Mailstop 111 D, Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121
    Am J Respir Crit Care Med 173:219-25. 2006
    ..Mice infected with Mycoplasma pulmonis can develop localized, life-long airway infection accompanied by persistent inflammation and remodeling...
  14. ncbi request reprint c-Kit immunophenotyping and metalloproteinase expression profiles of mast cells in interstitial lung diseases
    Samuel T Edwards
    Cardiovascular Research Institute, University of California, San Francisco, California 94143 0911, USA
    J Pathol 206:279-90. 2005
    ..We conclude that ILD microenvironments induce unique c-Kit receptor and metalloproteinase mast cell phenotypes...

Research Grants5

  1. Mast Cells and the Host Response in the Lung
    Paul Wolters; Fiscal Year: 2004
    ..This knowledge can then be applied to the development of new treatments for bacterial pneumonia that modulate the activity of specific mast cells proteins in ways that improve survival. ..
  2. MAST CELL CYSTEINE PROTEASES IN LUNG INFLAMMATION
    Paul Wolters; Fiscal Year: 2003
    ..McKerrow), immunohistopathology (Dr. McDonald), and pulmonary diseases (Dr. Matthay), who will guide the candidates development into an independent investigator in pulmonary research. ..
  3. Mast Cells and the Host Response in the Lung
    Paul Wolters; Fiscal Year: 2005
    ..This knowledge can then be applied to the development of new treatments for bacterial pneumonia that modulate the activity of specific mast cells proteins in ways that improve survival. ..
  4. Mast Cells and the Host Response in the Lung
    Paul Wolters; Fiscal Year: 2006
    ..This knowledge can then be applied to the development of new treatments for bacterial pneumonia that modulate the activity of specific mast cells proteins in ways that improve survival. ..
  5. Mast Cells and the Host Response in the Lung
    Paul Wolters; Fiscal Year: 2007
    ..This knowledge can then be applied to the development of new treatments for bacterial pneumonia that modulate the activity of specific mast cells proteins in ways that improve survival. ..