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Bain F, Fischer L, Chen R, Wold M. Single-Molecule Analysis of Replication Protein A-DNA Interactions. Methods Enzymol. 2018;600:439-461
..Finally, the last section describes how to analyze TIRFM data. This chapter will focus on human RPA. However, these methods can be applied to RPA homologs from other species. ..
Chen R, Subramanyam S, Elcock A, Spies M, Wold M. Dynamic binding of replication protein a is required for DNA repair. Nucleic Acids Res. 2016;44:5758-72
..It is likely that the binding modes are in equilibrium and reflect dynamics in the RPA-DNA complex. This suggests that dynamic binding of RPA to DNA is necessary for different cellular functions. ..
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