Research Topics
Species | Katherine WisnerSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
Prevention of postpartum episodes in women with bipolar disorderKatherine L Wisner
Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
Biol Psychiatry 56:592-6. 2004..The aim of this study was to evaluate the efficacy of divalproex (VLP) to prevent episode recurrence in postpartum women with bipolar disorder...
Web-based education for postpartum depression: conceptual development and impactKatherine L Wisner
Epidemiology and Women s Studies, University of Pittsburgh, Pittsburgh, PA 15213, USA
Arch Womens Ment Health 11:377-85. 2008..The site promotes education and training in PPD treatment that is flexible, cost-effective, and meets the needs of health care professionals...- Major depression and antidepressant treatment: impact on pregnancy and neonatal outcomesKatherine L Wisner
Women s Behavioral HealthCARE and the Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara St, Pittsburgh, PA 15213, USA
Am J Psychiatry 166:557-66. 2009..This study examined whether 1) minor physical anomalies, 2) maternal weight gain and infant birth weight, 3) preterm birth, and 4) neonatal adaptation are affected by SSRI or depression exposure... - Postpartum depression: a randomized trial of sertraline versus nortriptylineKatherine L Wisner
Department of Obstetrics and Gynecology and Reproductive Sciences, Epidemiology and Women s Studies, Western Psychiatric Institute and Clinic University of Pittsburgh Medical Center, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Clin Psychopharmacol 26:353-60. 2006..Women who were responders and remitters at week 8 could be identified earlier if they were treated with SERT than with NTP. Breast-fed infant serum levels were near or below the level of quantifiability for both agents... - Valproate prescription prevalence among women of childbearing ageKatherine L Wisner
Women s Behavioral HealthCARE, Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
Psychiatr Serv 62:218-20. 2011..The frequency of valproate use for mental health conditions among women of childbearing age was determined... - Prevention of postpartum depression: a pilot randomized clinical trialKatherine L Wisner
Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA
Am J Psychiatry 161:1290-2. 2004..The authors attempted to reduce the rate of postpartum depression in high-risk women and to increase the time to recurrence... - Pharmacotherapy for depressed pregnant women: overcoming obstacles to gathering essential dataK L Wisner
Departments of Psychiatry, Obstetrics, Gynecology and Reproductive Sciences, Epidemiology, and Women s Studies, Pittsburgh, Pennsylvania, USA
Clin Pharmacol Ther 86:362-5. 2009..Mandating the collection of reproductive outcome data in exposed childbearing women is an overdue step toward societal responsibility to our most vulnerable members... - Postpartum depression recurrence versus discontinuation syndrome: observations from a randomized controlled trialKeerthy R Sunder
Department of Psychiatry, and Women's Behavioral HealthCARE, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
J Clin Psychiatry 65:1266-8. 2004.... - Randomized clinical trial of bright light therapy for antepartum depression: preliminary findingsC Neill Epperson
Department of Psychiatry, Yale University School of Medicine, University Towers Suite 2H, 100 York Street, New Haven, CT 06511, USA
J Clin Psychiatry 65:421-5. 2004..Bright light therapy was shown to be a promising treatment for depression during pregnancy in a recent open-label study. In an extension of this work, we report findings from a double-blind placebo-controlled pilot study... - Management of bipolar disorder during pregnancy and the postpartum periodKimberly A Yonkers
Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, USA
Am J Psychiatry 161:608-20. 2004..The authors summarize knowledge regarding the management of bipolar disorder during pregnancy and the postpartum period, with a focus on managing mania, hypomania, and the psychotic components of the illness... - Timing of depression recurrence in the first year after birthKatherine L Wisner
Western Psychiatric Institute and Clinic University of Pittsburgh Medical Center, 3811 O Hara St, Pittsburgh, PA 15213, USA
J Affect Disord 78:249-52. 2004..Women who have suffered from one episode of postpartum-onset major depression (PPMD) experience increased risk for recurrence in the year following another birth... - Are maternal depression or symptom severity associated with breastfeeding intention or outcomes?Debra L Bogen
Department of Pediatrics, University of Pittsburgh School of Medicine, Children s Hospital of Pittsburgh, Division of General Academic Pediatrics, Pittsburgh, PA 15213, USA
J Clin Psychiatry 71:1069-78. 2010.... 
A review of postpartum psychosisDorothy Sit
University of Pittsburgh, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
J Womens Health (Larchmt) 15:352-68. 2006..The objective is to provide an overview of the clinical features, prognosis, differential diagnosis, evaluation, and treatment of postpartum psychosis...- Treatment with selective serotonin reuptake inhibitors during pregnancy: deceleration of weight gain because of depression or drug?Lisa M Bodnar
Department of Epidemiology, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, PA 15261, USA
Am J Psychiatry 163:986-91. 2006 - Disposition of chiral and racemic fluoxetine and norfluoxetine across childbearingDorothy Sit
Women s Behavioral HealthCARE, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
J Clin Psychopharmacol 30:381-6. 2010.... - Sleep complaints in late pregnancy and the recurrence of postpartum depressionMichele L Okun
Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Behav Sleep Med 7:106-17. 2009..9 vs. 7.3 for non-recurrers, p = .02). Sleep quality in late pregnancy may help in identifying women at risk for a PPMD recurrence... - Abnormally reduced dorsomedial prefrontal cortical activity and effective connectivity with amygdala in response to negative emotional faces in postpartum depressionEydie L Moses-Kolko
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Am J Psychiatry 167:1373-80. 2010..The authors examined activity in response to negative emotional faces in the dorsomedial pre-frontal cortex and amygdala, key emotion regulatory neural regions of importance to both mothering and depression... - Psychiatric outcomes following medical and surgical abortionDorothy Sit
Department of Psychiatry, University of Pittsburgh School of Medicine, PA 15213, USA
Hum Reprod 22:878-84. 2007..The objectives were to determine post-abortion depression risk, evaluate risk factors for post-abortion depression and to explore the relationship between cortisol and depression... - Changes in antidepressant metabolism and dosing across pregnancy and early postpartumDorothy K Sit
Western Psychiatric Institute and Clinic, School of Medicine, University of Pittsburgh, PA 15213, USA
J Clin Psychiatry 69:652-8. 2008..We examined the dose requirements and level-to-dose (L/D) ratios of citalopram, escitalopram, and sertraline during pregnancy and after birth... - Serotonin 1A receptor reductions in postpartum depression: a positron emission tomography studyEydie L Moses-Kolko
Department of Psychiatry, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA
Fertil Steril 89:685-92. 2008..To measure brain serotonin-1A (5HT1A) receptor binding potential (BP) in healthy and depressed postpartum women... - Screening for depression in the postpartum period: a comparison of three instrumentsBarbara H Hanusa
Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Womens Health (Larchmt) 17:585-96. 2008.... - Light therapy for bipolar disorder: a case series in womenDorothy Sit
Women s Behavioral HealthCARE, Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Bipolar Disord 9:918-27. 2007..To perform a dose-ranging safety and efficacy study of bright light therapy for depression in women with bipolar disorder (BD)... - Neonatal signs after late in utero exposure to serotonin reuptake inhibitors: literature review and implications for clinical applicationsEydie L Moses-Kolko
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
JAMA 293:2372-83. 2005..Integration of data about the neonatal behavioral syndrome into the management of pregnancy in women who take SRIs is a current challenge for physicians... - Transdermal estradiol for postpartum depression: a promising treatment optionEydie L Moses-Kolko
Department of Psychiatry, Women s Behavioral HealthCARE, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Clin Obstet Gynecol 52:516-29. 2009.... - Identification of postpartum depressionDorothy K Y Sit
Department of Psychiatry, Western Psychiatric Institute and Clinic University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Clin Obstet Gynecol 52:456-68. 2009..Finally, we explore how to manage patients who screen positive for depression and treatment options for women with PPD... - Pharmacotherapy of postpartum depressionTeresa Lanza di Scalea
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Expert Opin Pharmacother 10:2593-607. 2009..Despite its detrimental impact on the health of the mother-infant dyad, there is a paucity of data in the literature regarding the efficacy of pharmacological treatment of PPD... - Best practices: an emerging best practice model for perinatal depression careDorothy K Y Sit
Women s Behavioral HealthCARE, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
Psychiatr Serv 60:1429-31. 2009..Most participants had moderate or severe major depressive disorder. Women contended with multiple treatment barriers. Colocated depression care was highly acceptable and enabled evidence-based care delivery for at-risk mothers... - Serum bupropion levels in 2 breastfeeding mother-infant pairsSusan W Baab
Frances Payne Bolton School of Nursing, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
J Clin Psychiatry 63:910-1. 2002..CONCLUSION: We recommend obtaining and publishing additional serum level findings for breastfeeding mother-infant pairs since data for bupropion are favorable but limited... - Prepregnancy body mass index, gestational weight gain, and the likelihood of major depressive disorder during pregnancyLisa M Bodnar
Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
J Clin Psychiatry 70:1290-6. 2009..We assessed the relation between prepregnancy body mass index (BMI) and the likelihood of major depressive disorder (MDD) during pregnancy and tested whether this association was modified by gestational weight gain... - Mental health is fundamental to healthKatherine L Wisner
Western Psychiatric Institute and Clinic and Women's Behavioral HealthCARE, University of Pittsburgh Medical Center, USA
J Am Med Womens Assoc 59:75-6. 2004 - Is difficult childbirth related to postpartum maternal outcomes in the early postpartum period?Diane F Hunker
Department of Nursing, Chatham University, 118 Coolidge Hall, Woodland Road, Pittsburgh, PA 15232, USA
Arch Womens Ment Health 12:211-9. 2009..001, p = .92). Adverse events did not predict maternal outcomes at 2-weeks postpartum. Social support was related to depressive symptoms, functional status and infant care, but did not moderate the effects of adverse events... - The management of depression during pregnancy: a report from the American Psychiatric Association and the American College of Obstetricians and GynecologistsKimberly A Yonkers
Department of Psychiatry, Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06510, USA
Gen Hosp Psychiatry 31:403-13. 2009..To address the maternal and neonatal risks of both depression and antidepressant exposure and develop algorithms for periconceptional and antenatal management... - The efficacy of light therapy in the treatment of mood disorders: a review and meta-analysis of the evidenceRobert N Golden
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7160, USA
Am J Psychiatry 162:656-62. 2005..The purpose of this study was to assess the evidence base for the efficacy of light therapy in treating mood disorders... - The management of depression during pregnancy: a report from the American Psychiatric Association and the American College of Obstetricians and GynecologistsKimberly A Yonkers
Department of Psychiatry, Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06510, USA
Obstet Gynecol 114:703-13. 2009..To address the maternal and neonatal risks of both depression and antidepressant exposure and develop algorithms for periconceptional and antenatal management... - Nutrition and depression: implications for improving mental health among childbearing-aged womenLisa M Bodnar
Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
Biol Psychiatry 58:679-85. 2005..Greater attention to nutritional factors in mental health is warranted given that nutrition interventions can be inexpensive, safe, easy to administer, and generally acceptable to patients... - Bridging the gap: recruitment of African-American women into mental health research studiesJudith A Meinert
Women's Mental HealthCARE, Case Western Reserve University, Cleveland, OH, USA
Acad Psychiatry 27:21-8. 2003..On the basis of this experience, the authors formulated a five-pronged approach for recruitment of African-American women into their study. The NIH guidelines were useful for this purpose... - Omega-3 fatty acids and supportive psychotherapy for perinatal depression: a randomized placebo-controlled studyMarlene P Freeman
Women s Mental Health Center, University of Texas Southwestern Medical Center, Dallas TX, USA
J Affect Disord 110:142-8. 2008..This study was designed to investigate the feasibility, safety, and efficacy of omega-3 fatty acids for perinatal depression in addition to supportive psychotherapy... - Clinical practice. Postpartum depressionKatherine L Wisner
Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
N Engl J Med 347:194-9. 2002 - Successful recruitment strategies for women in postpartum mental health trialsKathleen S Peindl
Department of Psychiatry and Human Behavior, Thomas Jefferson University, 833 Chestnut Street, Suite 210 E, Philadelphia, PA 19107, USA
J Psychiatr Res 37:117-25. 2003..Those materials contributed 44% of screening calls for the treatment study. Our conclusions were that women were most likely to enter the research studies when referred by an obstetrician or other professional... - Brightening depressionAnna Wirz-Justice
Science 303:467-9. 2004 - The impact of postpartum depression on motheringM Cynthia Logsdon
School of Nursing at University of Louisville, Louisville, KY, USA
J Obstet Gynecol Neonatal Nurs 35:652-8. 2006..Recommendations for health care practice include screening for depression across the first postpartum year and developing a strong network for mental health referrals... - Identifying depression in the first postpartum year: guidelines for office-based screening and referralKathleen S Peindl
Department of Psychiatry and Human Behavior, Jefferson College of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA
J Affect Disord 80:37-44. 2004..The outcome of the study was identification of a recurrence of major depression in the first year postpartum by a clinical interview and the EPDS. We had the unique opportunity to examine the relationship between EPDS scores and PPMD... - An open trial of morning light therapy for treatment of antepartum depressionDan A Oren
Pychiatry Department, Yale University, New Haven, CT, USA
Am J Psychiatry 159:666-9. 2002..No pharmacotherapy is specifically approved for antepartum depression; novel treatment approaches may be welcome. The authors explored the use of morning bright light therapy for antepartum depression... - Antidepressants and premature laborKeerthy Sunder
Am J Psychiatry 161:925-6; author reply 926. 2004 - Pooled analysis of antidepressant levels in lactating mothers, breast milk, and nursing infantsAlicia M Weissman
Department of Family Medicine, University of Iowa, Iowa City, Iowa 52242, USA
Am J Psychiatry 161:1066-78. 2004..Current data do not support monitoring breast milk levels in individual patients. Future researchers should report maternal, breast milk, and infant antidepressant levels along with other appropriate variables... - Antidepressant use in pregnancy: new concerns, old dilemmasChristina Chambers
Expert Rev Neurother 7:761-4. 2007 - SSRIs and birth defectsMonique B Kelly
Epidemiology 18:411-2; author reply 412-3. 2007 - Collaborative management of women with bipolar disorder during pregnancy and postpartum: pharmacologic considerationsSheila Ward
Department of Obstetrics, Gynecology and Women s Health, University of Louisville School of Medicine, Louisville, KY 40292, USA
J Midwifery Womens Health 52:3-13. 2007..Communication and careful comanagement between the obstetric and psychiatric team is essential when treating women with bipolar disorder during the reproductive years... - No interruption of lactation is needed after (11)C-WAY 100635 or (11)C-raclopride PETEydie L Moses-Kolko
J Nucl Med 46:1765. 2005 - Weight changes in postpartum women with remitted depressionBarbara L Gracious
Department of Psychiatry and Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY, USA
J Clin Psychiatry 66:291-3. 2005..1 lb). CONCLUSIONS: Weight loss was not compromised by antidepressant pharmacotherapy. Postpartum weight retention occurred in this group of nondepressed women with previous histories of major depression independent of drug treatment... - Postpartum depression: a major public health problemKatherine L Wisner
JAMA 296:2616-8. 2006 - Pregnancy outcomes in schizophreniaMarlene P Freeman
Am J Psychiatry 159:1609; author reply 1609. 2002 - St John's wort and depressionJerry Cott
JAMA 288:448; author reply 448-9. 2002 - Verapamil treatment for women with bipolar disorderKatherine L Wisner
Women's Mental HealthCARE, Louisville, Kentucky 40202, USA
Biol Psychiatry 51:745-52. 2002..After decades of case reports and underpowered clinical trials, we must definitively study verapamil for efficacy and gender specificity in bipolar disorder...
Research Grants
- Identification and Therapy of Postpartum DepressionKatherine Wisner; Fiscal Year: 2007..We have developed a multi-disciplinary team with expertise in clinical research with depressed and minority women and health services to address these needs. ..
- POSTPARTUM DEPRESSION--NORTRIPTYLINE VS SERTRALINEKatherine Wisner; Fiscal Year: 2001....
- Transdermal Estradiol for Postpartum Depression.Katherine Wisner; Fiscal Year: 2009....
- Antimanic Use During PregnancyKatherine Wisner; Fiscal Year: 2009..No such PK data are currently available. ..
- Transdermal Estradiol for Postpartum Depression.Katherine L Wisner; Fiscal Year: 2010....
- Identification and Therapy of Postpartum DepressionKatherine L Wisner; Fiscal Year: 2010..We have developed a multi-disciplinary team with expertise in clinical research with depressed and minority women and health services to address these needs. ..
- Antimanic Use During PregnancyKatherine Wisner; Fiscal Year: 2007..No such PK data are currently available. ..
- Transdermal Estradiol for Postpartum Depression.Katherine Wisner; Fiscal Year: 2007....
- SSRI Rx: Effects on Self Efficacy and Maternal RoleKatherine Wisner; Fiscal Year: 2003....
- ANTIDEPRESSANT USE DURING PREGNANCYKatherine Wisner; Fiscal Year: 2004..Data from this investigation will increase our sophistication in making risk-benefit decisions during pregnancy. ..
- PREVENTION OF RECURRENT POSTPARTUM MAJOR DEPRESSIONKatherine Wisner; Fiscal Year: 2005..Maternal MD, an exposure that clearly has a negative impact upon several aspects of child development, also will be considered as an exposure with effects on child outcomes. ..
- Antimanic Use During PregnancyKatherine L Wisner; Fiscal Year: 2010..No such PK data are currently available. ..