M Wintermark

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi The anterior cerebral artery is an appropriate arterial input function for perfusion-CT processing in patients with acute stroke
    Max Wintermark
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, 505 Parnassus Avenue, Box 0628, San Francisco, CA 94143 0628, USA
    Neuroradiology 50:227-36. 2008
  2. ncbi Automated versus manual post-processing of perfusion-CT data in patients with acute cerebral ischemia: influence on interobserver variability
    Bruno P Soares
    Department of Radiology, Neuroradiology Section, University of California, 505 Parnassus Avenue, Box 0628, San Francisco, CA 94143 0628, USA
    Neuroradiology 51:445-51. 2009
  3. ncbi Comparison of CT perfusion and angiography and MRI in selecting stroke patients for acute treatment
    M Wintermark
    Neuroradiology Section, Department of Radiology, University of California, San Francisco, San Francisco, CA 94143 0628, USA
    Neurology 68:694-7. 2007
  4. ncbi Comparative overview of brain perfusion imaging techniques
    M Wintermark
    Department of Radiology, Neuroradiology Section, University of California, 505 Parnassus Avenue, Room L358, Box 0628, San Francisco, CA 94143 0628, USA
    J Neuroradiol 32:294-314. 2005
  5. ncbi Carotid plaque computed tomography imaging in stroke and nonstroke patients
    Max Wintermark
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, San Francisco, CA 94143 0628, USA
    Ann Neurol 64:149-57. 2008
  6. ncbi Semi-automated computer assessment of the degree of carotid artery stenosis compares favorably to visual evaluation
    Max Wintermark
    University of California, San Francisco, Department of Radiology, San Francisco, CA, United States
    J Neurol Sci 269:74-9. 2008
  7. ncbi Iodinated and gadolinium contrast media in computed tomography (CT) and magnetic resonance (MR) stroke imaging
    Max Wintermark
    University of California, San Francisco, Department of Radiology, Neuroradiology Section, San Francisco, USA
    Curr Med Chem 13:2717-23. 2006
  8. ncbi Brain perfusion-CT in acute stroke patients
    Max Wintermark
    Department of Radiology, University of California San Francisco UCSF, 505 Parnassus Avenue, Box 0628, San Francisco, CA 94143, USA
    Eur Radiol 15:D28-31. 2005
  9. ncbi Perfusion-CT assessment of infarct core and penumbra: receiver operating characteristic curve analysis in 130 patients suspected of acute hemispheric stroke
    Max Wintermark
    Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
    Stroke 37:979-85. 2006
  10. ncbi Unmasking complicated atherosclerotic plaques on carotid magnetic resonance angiography: a report of three cases
    Max Wintermark
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, CA 94143, USA
    J Vasc Surg 44:884-7. 2006

Research Grants

  1. Advanced NeuroImaging for Acute Stroke Treatment
    Max Wintermark; Fiscal Year: 2007

Detail Information

Publications85

  1. ncbi The anterior cerebral artery is an appropriate arterial input function for perfusion-CT processing in patients with acute stroke
    Max Wintermark
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, 505 Parnassus Avenue, Box 0628, San Francisco, CA 94143 0628, USA
    Neuroradiology 50:227-36. 2008
    ..The goals of this study were to determine how the AIF selection influences PCT results in acute stroke patients and whether the ACA is an appropriate default AIF...
  2. ncbi Automated versus manual post-processing of perfusion-CT data in patients with acute cerebral ischemia: influence on interobserver variability
    Bruno P Soares
    Department of Radiology, Neuroradiology Section, University of California, 505 Parnassus Avenue, Box 0628, San Francisco, CA 94143 0628, USA
    Neuroradiology 51:445-51. 2009
    ..The purpose of this study is to compare the variability of PCT results obtained by automatic selection of the arterial input function (AIF), venous output function (VOF) and symmetry axis versus manual selection...
  3. ncbi Comparison of CT perfusion and angiography and MRI in selecting stroke patients for acute treatment
    M Wintermark
    Neuroradiology Section, Department of Radiology, University of California, San Francisco, San Francisco, CA 94143 0628, USA
    Neurology 68:694-7. 2007
    ..Relying on MRI or PCT/CTA would have led to the same treatment decisions in all cases but one...
  4. ncbi Comparative overview of brain perfusion imaging techniques
    M Wintermark
    Department of Radiology, Neuroradiology Section, University of California, 505 Parnassus Avenue, Room L358, Box 0628, San Francisco, CA 94143 0628, USA
    J Neuroradiol 32:294-314. 2005
    ..For clinicians, this paper should offers a clearer picture of the pros and cons of currently available brain perfusion imaging techniques, and assist them in choosing the proper method in every specific clinical setting...
  5. ncbi Carotid plaque computed tomography imaging in stroke and nonstroke patients
    Max Wintermark
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, San Francisco, CA 94143 0628, USA
    Ann Neurol 64:149-57. 2008
    ..To identify a set of computed tomographic (CT) features of carotid atherosclerotic plaques that is significantly associated with ischemic stroke...
  6. ncbi Semi-automated computer assessment of the degree of carotid artery stenosis compares favorably to visual evaluation
    Max Wintermark
    University of California, San Francisco, Department of Radiology, San Francisco, CA, United States
    J Neurol Sci 269:74-9. 2008
    ..The findings of the neuroradiologist and computer assessment were compared using Chi2 tests/kappa calculations and linear regression for categorical and continuous measurements of carotid stenosis, respectively...
  7. ncbi Iodinated and gadolinium contrast media in computed tomography (CT) and magnetic resonance (MR) stroke imaging
    Max Wintermark
    University of California, San Francisco, Department of Radiology, Neuroradiology Section, San Francisco, USA
    Curr Med Chem 13:2717-23. 2006
    ..The objective of this review article is to present the advantages and drawbacks of CT, using iodinated contrast, and MRI, using gadolinium, in the evaluation of acute stroke patients...
  8. ncbi Brain perfusion-CT in acute stroke patients
    Max Wintermark
    Department of Radiology, University of California San Francisco UCSF, 505 Parnassus Avenue, Box 0628, San Francisco, CA 94143, USA
    Eur Radiol 15:D28-31. 2005
    ..Using PCT and CTA to define new individualized strategies for acute reperfusion will allow more acute stroke patients to benefit from thrombolytic therapy...
  9. ncbi Perfusion-CT assessment of infarct core and penumbra: receiver operating characteristic curve analysis in 130 patients suspected of acute hemispheric stroke
    Max Wintermark
    Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
    Stroke 37:979-85. 2006
    ....
  10. ncbi Unmasking complicated atherosclerotic plaques on carotid magnetic resonance angiography: a report of three cases
    Max Wintermark
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, CA 94143, USA
    J Vasc Surg 44:884-7. 2006
    ....
  11. ncbi Comparative overview of brain perfusion imaging techniques
    Max Wintermark
    Department of Radiology, University of California, 505 Parnassus Ave, San Francisco, CA 94143 0628, USA
    Stroke 36:e83-99. 2005
    ..All of them are used to characterize the same types of pathological conditions. However, each technique has its own advantages and drawbacks...
  12. ncbi Visual grading system for vasospasm based on perfusion CT imaging: comparisons with conventional angiography and quantitative perfusion CT
    Max Wintermark
    Department of Radiology, University of California, San Francisco, CA 94143, USA
    Cerebrovasc Dis 26:163-70. 2008
    ..The purpose of this study was to compare simple visual grading of perfusion CT (PCT) maps to a more quantitative, threshold-based interpretation of PCT parameters in the characterization of presence and severity of vasospasm...
  13. ncbi High-resolution CT imaging of carotid artery atherosclerotic plaques
    M Wintermark
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, CA 94143 0628, USA
    AJNR Am J Neuroradiol 29:875-82. 2008
    ....
  14. ncbi Acute stroke imaging research roadmap
    Max Wintermark
    Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
    AJNR Am J Neuroradiol 29:e23-30. 2008
    ..The present article summarizes these recommendations and examines practical steps to achieve them...
  15. ncbi Acute stroke imaging research roadmap
    Max Wintermark
    University of California, San Francisco, Department of Radiology, Neuroradiology Section, 505 Parnassus Avenue, Box 0628, San Francisco, CA 94143 0628, USA
    Stroke 39:1621-8. 2008
    ..The present article summarizes these recommendations and examines practical steps to achieve them...
  16. ncbi Cerebral perfusion CT: technique and clinical applications
    M Wintermark
    Department of Radiology, Neuroradiology Section, University of California, 505, Parnassus Avenue, Box 0628, San Francisco, CA 94143 0628, USA
    J Neuroradiol 35:253-60. 2008
    ..This article provides an overview of PCT, including details of technique, major clinical applications, and limitations...
  17. ncbi Optimal brain perfusion CT coverage in patients with acute middle cerebral artery stroke
    A D Furtado
    Department of Radiology, University of California, San Francisco, 94143 0628, USA
    AJNR Am J Neuroradiol 31:691-5. 2010
    ....
  18. ncbi Dynamic perfusion CT assessment of the blood-brain barrier permeability: first pass versus delayed acquisition
    J W Dankbaar
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, San Francisco, CA 94143 0628, USA
    AJNR Am J Neuroradiol 29:1671-6. 2008
    ..The goal of this study was to assess whether the first pass or the delayed phase of a contrast bolus injection better respects the assumptions of the Patlak model for the assessment of BBBP in patients with acute stroke by using PCT...
  19. ncbi Age- and anatomy-related values of blood-brain barrier permeability measured by perfusion-CT in non-stroke patients
    J W Dankbaar
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, 505, Parnassus Avenue, Box 0628, San Francisco, CA 94143 0628, USA
    J Neuroradiol 36:219-27. 2009
    ....
  20. ncbi Dynamic perfusion-CT assessment of early changes in blood brain barrier permeability of acute ischaemic stroke patients
    J W Dankbaar
    University of California, Department of Radiology and Biomedical Imaging, Neuroradiology Section, San Francisco, USA
    J Neuroradiol 38:161-6. 2011
    ..The purpose of this study was to evaluate the effect of patient characteristics and stroke severity on admission BBB permeability (BBBP) values measured with perfusion-CT (PCT) in acute ischaemic stroke patients...
  21. ncbi Blood-brain barrier permeability assessed by perfusion CT predicts symptomatic hemorrhagic transformation and malignant edema in acute ischemic stroke
    J Hom
    Department of Radiology, Neuroradiology Section, Neurovascular Service, University of California, San Francisco, California, USA
    AJNR Am J Neuroradiol 32:41-8. 2011
    ..Our goal was to evaluate the sensitivity and specificity of admission BBBP measurements derived from PCT in predicting the development of SHT and ME in patients with acute ischemic stroke...
  22. ncbi Delay correction for the assessment of blood-brain barrier permeability using first-pass dynamic perfusion CT
    T Schneider
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, San Francisco, California, USA
    AJNR Am J Neuroradiol 32:E134-8. 2011
    ..Unfortunately, Patlak assumptions require extended PCT acquisition, increasing the risk of motion artifacts. A necessary correction is presented for obtaining accurate BBB permeability measurements from first-pass PCT...
  23. ncbi Accuracy of dynamic perfusion CT with deconvolution in detecting acute hemispheric stroke
    Max Wintermark
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, USA
    AJNR Am J Neuroradiol 26:104-12. 2005
    ..2%, 91.8%, and 87.9% in showing the extent. CONCLUSION: Dynamic PCT maps are more accurate than nonenhanced CT in detecting hemispheric strokes. Despite limited spatial coverage, PCT is highly reliable to assess the stroke extent...
  24. ncbi Optimal carotid artery coverage for carotid plaque CT-imaging in predicting ischemic stroke
    S Arora
    University of California San Francisco, Department of Radiology, Neuroradiology Section, 505, Parnassus Avenue, Box 0628, San Francisco, CA 94143, United States
    J Neuroradiol 37:98-103. 2010
    ..To determine the optimal spatial coverage for CT-imaging of carotid atherosclerosis, allowing the most accurate prediction of the associated risk of ischemic stroke...
  25. ncbi Vasospasm after subarachnoid hemorrhage: utility of perfusion CT and CT angiography on diagnosis and management
    M Wintermark
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, San Francisco, CA 94143, USA
    AJNR Am J Neuroradiol 27:26-34. 2006
    ..However promising, the value of PCT for selecting the best management strategy in such patients will need to be further investigated...
  26. ncbi Correlation of early dynamic CT perfusion imaging with whole-brain MR diffusion and perfusion imaging in acute hemispheric stroke
    James D Eastwood
    Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA
    AJNR Am J Neuroradiol 24:1869-75. 2003
    ..47, P =.02). CONCLUSION: Good correlation was seen between CT and MR for CBF and MTT abnormalities. It remains uncertain whether CT perfusion CBV abnormalities correspond well to whole-brain abnormalities...
  27. ncbi Optimal duration of acquisition for dynamic perfusion CT assessment of blood-brain barrier permeability using the Patlak model
    J Hom
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif 94143 0628, USA
    AJNR Am J Neuroradiol 30:1366-70. 2009
    ..Our goal was to determine the optimal duration of the delayed PCT acquisition to obtain accurate BBBP measurements while minimizing potential motion artifacts and radiation dose...
  28. ncbi Cerebral perfusion-CT patterns following seizure
    J M Gelfand
    Department of Neurology, Neuroradiology Section, University of California, San Francisco, CA 94143 0114, USA
    Eur J Neurol 17:594-601. 2010
    ..Cerebral perfusion-CT (PCT) is commonly used to image patients with suspected stroke, but PCT may also be useful in detecting abnormalities following seizure...
  29. ncbi Perfusion CT compared to H(2) (15)O/O (15)O PET in patients with chronic cervical carotid artery occlusion
    Amita Kamath
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, San Francisco, CA 94143 0628, USA
    Neuroradiology 50:745-51. 2008
    ..The purpose of this study was to compare the results of perfusion computed tomography (PCT) with those of (15)O(2)/H(2) (15)O positron emission tomography (PET) in a subset of Carotid Occlusion Surgery Study (COSS) patients...
  30. ncbi Advanced CT and MR imaging techniques: an academic whim or a clinical standard in the making?
    M Wintermark
    Department of Radiology, Neuroradiology Section, University of California San Francisco, San Francisco, CA, USA
    AJNR Am J Neuroradiol 27:1257. 2006
  31. ncbi Restricted diffusion in bilateral optic nerves and retinas as an indicator of venous ischemia caused by cavernous sinus thrombophlebitis
    J S Chen
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, CA 94143-0628, USA
    AJNR Am J Neuroradiol 27:1815-6. 2006
    ..This case shows that both retinal and optic nerve ischemia can be the cause of blindness after CST. Arguments supporting an arterial-versus-venous origin for the ischemia are discussed...
  32. ncbi Accuracy and anatomical coverage of perfusion CT assessment of the blood-brain barrier permeability: one bolus versus two boluses
    Jan Willem Dankbaar
    Neuroradiology Section, Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
    Cerebrovasc Dis 26:600-5. 2008
    ..To assess whether blood-brain barrier permeability (BBBP) values, extracted with the Patlak model from the second perfusion CT (PCT) contrast bolus, are significantly lower than the values extracted from the first bolus in the same patient...
  33. ncbi Prospective evaluation of multidetector-row CT angiography for the diagnosis of vasospasm following subarachnoid hemorrhage: a comparison with digital subtraction angiography
    Saadia R Chaudhary
    Neuroradiology Section, Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
    Cerebrovasc Dis 25:144-50. 2008
    ..To evaluate the accuracy of multidetector-row CT angiography (CTA) for the diagnosis of large-vessel vasospasm following subarachnoid hemorrhage by comparison to digital subtraction angiography (DSA)...
  34. ncbi Perfusion-CT assessment of the cerebrovascular reserve: a revisit to the acetazolamide challenges
    L McG Smith
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, 505 Parnassus Avenue, P O Box 0628, San Francisco, CA 94143 0628, USA
    J Neuroradiol 35:157-64. 2008
    ..The goal of this study is to clarify the interpretation of PCT studies obtained during acetazolamide challenges...
  35. ncbi Perfusion CT Imaging Follows Clinical Severity in Left Hemispheric Strokes
    A D Furtado
    Neuroradiology Section, Department of Radiology, University of California, San Francisco, San Francisco, California 94143 0628, USA
    Eur Neurol 60:244-52. 2008
    ....
  36. ncbi Cerebral vascular autoregulation assessed by perfusion-CT in severe head trauma patients
    M Wintermark
    Department of Radiology, Neuroradiology Section, University of California, 505 Parnassus Avenue, Box 0628, San Francisco, CA 94143-0628, USA. max.wintermarkadiology.ucsf.edu
    J Neuroradiol 33:27-37. 2006
    ..It could hence be used as a guide for brain edema therapy, as well as to monitor the treatment efficiency...
  37. ncbi How accurate is CT angiography in evaluating intracranial atherosclerotic disease?
    Mai N Nguyen-Huynh
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Stroke 39:1184-8. 2008
    ..However, it is invasive and can only be carried out at specialized centers. We sought to compare CT angiography (CTA) to DSA for detection and measurement of stenosis in large intracranial arteries...
  38. ncbi Carotid atheroma rupture observed in vivo and FSI-predicted stress distribution based on pre-rupture imaging
    Joseph R Leach
    UC Berkeley UC San Francisco Joint Graduate Group in Bioengineering, Berkeley, CA, USA
    Ann Biomed Eng 38:2748-65. 2010
    ..Within these bounds, we find a region of pronounced elevation in stress within the fibrous plaque layer of the lesion with a location and extent corresponding to that of the observed site of plaque rupture...
  39. ncbi Multimodal CT in stroke imaging: new concepts
    Carlos J Ledezma
    Morristown Memorial Hospital, Department of Radiology, 100 Madison Avenue, Morristown, NJ 07962, USA
    Radiol Clin North Am 47:109-16. 2009
    ..This article discusses the individual components of multimodal CT and addresses the potential role of a combined multimodal CT stroke protocol in acute stroke therapy...
  40. ncbi Difference in disease burden and activity in pediatric patients on brain magnetic resonance imaging at time of multiple sclerosis onset vs adults
    Emmanuelle Waubant
    UCSF Regional Pediatric Multiple Sclerosis Center, 350 Parnassus Ave, Ste 908, San Francisco, CA 94117, USA
    Arch Neurol 66:967-71. 2009
    ..To compare initial brain magnetic resonance imaging (MRI) characteristics of children and adults at multiple sclerosis (MS) onset...
  41. ncbi Motor trephine syndrome: a mechanistic hypothesis
    Shirley I Stiver
    Department of Neurosurgery, University of California San Francisco, San Francisco General Hospital, 1001 Potrero Avenue, Room 101, San Francisco, CA 94110 0899, USA
    Acta Neurochir Suppl 102:273-7. 2008
    ..The goal of this study was to define causal factors associated with this syndrome...
  42. ncbi MRI of geometric and compositional features of vulnerable carotid plaque
    David Saloner
    Department of Radiology, VA Medical Centerand University of California San Francisco, San Francisco, CA 94121, USA
    Stroke 38:637-41. 2007
    ....
  43. ncbi Computer-aided assessment of head computed tomography (CT) studies in patients with suspected traumatic brain injury
    Esther L Yuh
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, and San Francisco General Hospital, San Francisco, California 94143 0628, USA
    J Neurotrauma 25:1163-72. 2008
    ..Further studies are required to evaluate the potential favorable impact of this software on facilitating workflow and improving diagnostic accuracy when used as a screening aid by physicians with different levels of experience...
  44. ncbi Reversible monoparesis following decompressive hemicraniectomy for traumatic brain injury
    Shirley I Stiver
    Department of Neurosurgery, School of Medicine, University of California, San Francisco, California 94110 0899, USA
    J Neurosurg 109:245-54. 2008
    ..The authors set out to study motor function systematically in this patient population to define the incidence, contributing factors, and outcome of patients with motor trephine syndrome...
  45. ncbi Reperfusion is a more accurate predictor of follow-up infarct volume than recanalization: a proof of concept using CT in acute ischemic stroke patients
    Bruno P Soares
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, 505 Parnassus Avenue, Box 0628, San Francisco, CA 94143 0628, USA
    Stroke 41:e34-40. 2010
    ..Material and..
  46. ncbi Systematic comparison of perfusion-CT and CT-angiography in acute stroke patients
    Jessica C Tan
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, CA 94143 0628, USA
    Ann Neurol 61:533-43. 2007
    ....
  47. ncbi Subclinical embolization after carotid artery stenting: new lesions on diffusion-weighted magnetic resonance imaging occur postprocedure
    Joseph H Rapp
    Vascular Surgery Service, San Francisco VA Medical Center, San Francisco, CA Division of Vascular Surgery, University of California San Francisco, San Francisco, CA, USA
    J Vasc Surg 45:867-72; discussion 872-4. 2007
    ..Because DWI lesions appear <or=1 hour of embolization, we used DWI to prospectively study patients before CAS, 1 hour after, and 48 hours after CAS to answer this question...
  48. ncbi Dynamic perfusion CT: optimizing the temporal resolution and contrast volume for calculation of perfusion CT parameters in stroke patients
    Max Wintermark
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, USA
    AJNR Am J Neuroradiol 25:720-9. 2004
    ..CONCLUSION: Temporal sampling intervals greater than 1 second can be used without altering the quantitative accuracy of PCT. Increased sampling intervals reduce the radiation dose and may allow for increased spatial coverage...
  49. ncbi Contrast extravasation on CT predicts mortality in primary intracerebral hemorrhage
    J Kim
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, San Francisco, CA 94143 0628, USA
    AJNR Am J Neuroradiol 29:520-5. 2008
    ....
  50. ncbi Monitoring serial change in the lumen and outer wall of vertebrobasilar aneurysms
    L Boussel
    Radiology Service, VA Medical Center, San Francisco, CA 94121, USA
    AJNR Am J Neuroradiol 29:259-64. 2008
    ..In this report we describe the use of MR imaging and 3D postprocessing methods to study the evolution of those aneurysms...
  51. ncbi Sixty-four-section multidetector CT angiography of carotid arteries: a systematic analysis of image quality and artifacts
    J J Kim
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, California 94143 0628, USA
    AJNR Am J Neuroradiol 31:91-9. 2010
    ..The goals of this study were to systematically measure image quality and determine the prevalence of various types of artifacts produced by a 64-section scanner...
  52. ncbi Radiation dose-reduction strategies for neuroradiology CT protocols
    A B Smith
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, CA 94143 0628, USA
    AJNR Am J Neuroradiol 28:1628-32. 2007
    ..This review will describe the available techniques for reducing dose associated with neuroradiologic CT imaging protocols...
  53. ncbi Modern imaging of the infarct core and the ischemic penumbra in acute stroke patients: CT versus MRI
    Carlos J Ledezma
    Morristown Memorial Hospital, Department of Radiology, Morristown, NJ, USA
    Expert Rev Cardiovasc Ther 7:395-403. 2009
    ..The objective of this article is to present the advantages and drawbacks of CT and MRI in the evaluation of acute stroke patients...
  54. ncbi The triple rule-out for acute ischemic stroke: imaging the brain, carotid arteries, aorta, and heart
    A D Furtado
    Department of Radiology, University of California, San Francisco, San Francisco, California, USA
    AJNR Am J Neuroradiol 31:1290-6. 2010
    ..The purpose of this study was to evaluate the image quality of a comprehensive CTA protocol in patients with acute stroke that expands the standard CTA coverage to include all 4 chambers of the heart and the coronary arteries...
  55. ncbi Unilateral putaminal CT, MR, and diffusion abnormalities secondary to nonketotic hyperglycemia in the setting of acute neurologic symptoms mimicking stroke
    Max Wintermark
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, USA
    AJNR Am J Neuroradiol 25:975-6. 2004
    ..A CT scan obtained 1 month later demonstrated faint hyperattenuation of the involved putamen. The reported pathophysiologic considerations for these imaging features are reviewed, and an original explanation is proposed...
  56. ncbi Carotid atherosclerosis does not predict coronary, vertebral, or aortic atherosclerosis in patients with acute stroke symptoms
    Dionesia D Adraktas
    Department of Radiology, University of California, San Francisco, San Francisco, Calif, USA
    Stroke 41:1604-9. 2010
    ....
  57. ncbi Local cortical hypoperfusion imaged with CT perfusion during postictal Todd's paresis
    Marlon S Mathews
    Department of Neurological Surgery, University of California, Irvine, CA, USA
    Neuroradiology 50:397-401. 2008
    ..However, it is unclear whether the pathophysiology of Todd's paralysis is related to alterations in cerebral perfusion. We report CT perfusion findings in a patient presenting with postictal aphasia and right hemiparesis...
  58. ncbi Interobserver variability in the assessment of CT imaging features of traumatic brain injury
    Kimberly A Chun
    Department of Radiology, Neuroradiology Section, University of California San Francisco, San Francisco, California 94143 0628, USA
    J Neurotrauma 27:325-30. 2010
    ..In conclusion, there is good interobserver reproducibility between neuroradiologists and neurosurgeons in the interpretation of CT imaging features of TBI and calculation of Marshall and Rotterdam scores...
  59. ncbi Optimization of perfusion imaging for acute cerebral ischemia: review of recent clinical trials and recommendations for future studies
    James M Provenzale
    Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710, USA
    AJR Am J Roentgenol 191:1263-70. 2008
    ..Numerous clinical trials have shed light on the efficacy of various reperfusion therapies; disparities in trial design have also left unanswered questions...
  60. ncbi Perfusion-CT of developmental venous anomalies: typical and atypical hemodynamic patterns
    H Kroll
    University of California, San Francisco, Department of Radiology, San Francisco, California 94143 0628, USA
    J Neuroradiol 37:239-42. 2010
    ..This pattern might help to stratify risks of associated complications such as hemorrhage...
  61. ncbi MR and CT monitoring of recanalization, reperfusion, and penumbra salvage: everything that recanalizes does not necessarily reperfuse!
    Bruno P Soares
    University of California, San Francisco, Department of Radiology, Neuroradiology Section, 505 Parnassus Avenue, Box 0628, San Francisco, CA 94143 0628, USA
    Stroke 40:S24-7. 2009
    ....
  62. ncbi Focal lesions in acute mild traumatic brain injury and neurocognitive outcome: CT versus 3T MRI
    Hana Lee
    Neurological Surgery, University of California, San Francisco, California 94143, USA
    J Neurotrauma 25:1049-56. 2008
    ....
  63. ncbi Hyperplastic anterior choroidal artery identified using magnetic resonance angiography: a report of two cases
    Letizia C L Antonietti
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, CA 94143-0628, USA
    Cerebrovasc Dis 22:450-2. 2006
  64. ncbi The future of stroke imaging: what we need and how to get to it
    Carlos Leiva-Salinas
    Department of Radiology, Neuroradiology Division, University of Virginia, Charlottesville, VA, USA
    Stroke 41:S152-3. 2010
    ..This article briefly describes the needs in this field and recommends future steps to achieve them...
  65. ncbi Radiation dose reduction strategy for CT protocols: successful implementation in neuroradiology section
    Alice B Smith
    Department of Radiology, Neuroradiology Section, University of California, San Francisco, CA 94143 0628, USA
    Radiology 247:499-506. 2008
    ..To retrospectively quantify the effect of systematic use of tube current modulation for neuroradiology computed tomographic (CT) protocols on patient dose and image quality...
  66. ncbi Investigation by perfusion CT and diffusion-weighted MR imaging
    Reto Meuli
    Department of Diagnostic and Interventional Radiology, University Hospital, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Adv Neurol 92:389-400. 2003
  67. ncbi Prognostic accuracy of cerebral blood flow measurement by perfusion computed tomography, at the time of emergency room admission, in acute stroke patients
    Max Wintermark
    Department of Diagnostic and Interventional Radiology, CHUV, Lausanne, Switzerland
    Ann Neurol 51:417-32. 2002
    ..It may also provide information about the extent of the penumbra. Perfusion CT could therefore be a valuable tool in the early management of acute stroke patients...
  68. ncbi Imaging of acute ischemic brain injury: the return of computed tomography
    Max Wintermark
    Department of Diagnostic and Interventional Radiology and Department of Neurology, University Hospital CHUV, Lausanne, Switzerland
    Curr Opin Neurol 16:59-63. 2003
    ..Classical and modern computed tomography imaging techniques, including conventional computed tomography, perfusion-computed tomography and computed tomography-angiography for acute stroke are reviewed...
  69. ncbi Imaging of acute traumatic injuries of the thoracic aorta
    Max Wintermark
    Department of Diagnostic and Interventional Radiology, University Hospital, CHUV-BH10, 1011 Lausanne, Switzerland
    Eur Radiol 12:431-42. 2002
    ..Knowledge of advantages and pitfalls of these imaging techniques, as reviewed in this article, will help the emergency radiologist to choose the appropriate algorithm in the diagnosis of traumatic aortic injury, for each trauma patient...
  70. ncbi Multislice computerized tomography angiography in the evaluation of intracranial aneurysms: a comparison with intraarterial digital subtraction angiography
    Max Wintermark
    Department of Diagnostic and Interventional Radiology, University Hospital CHUV, Lausanne, Switzerland
    J Neurosurg 98:828-36. 2003
    ....
  71. ncbi CT perfusion scanning with deconvolution analysis: pilot study in patients with acute middle cerebral artery stroke
    James D Eastwood
    Depts of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710 3808, USA
    Radiology 222:227-36. 2002
    ..To measure mean cerebral blood flow (CBF) in ischemic and nonischemic territories and in low-attenuation regions in patients with acute stroke by using deconvolution-derived hemodynamic imaging...
  72. ncbi Aphasia in hyperacute stroke: language follows brain penumbra dynamics
    Alexandre Croquelois
    Neurology Department, Centre Hospitalier Universitaire Vaudois, Rue du Bugnon 46, 1011 Lausanne, Switzerland
    Ann Neurol 54:321-9. 2003
    ..Further studies on the relevance of penumbra dynamics in function-specific brain areas to decision taking in hyperacute stroke management are required...
  73. ncbi Multimodal imaging of striatal degeneration in Amish patients with glutaryl-CoA dehydrogenase deficiency
    Kevin A Strauss
    Clinic for Special Children, 535 Bunker Hill Road, Strasburg, PA 17579, USA
    Brain 130:1905-20. 2007
    ..04, 95% confidence interval = 0.01-0.34; P < 0.001)...
  74. ncbi Acute brain perfusion disorders in children assessed by quantitative perfusion computed tomography in the emergency setting
    Max Wintermark
    Department of Diagnostic and Interventional Radiology, University Hospital CHUV, Lausanne, Switzerland
    Pediatr Emerg Care 21:149-60. 2005
    ..The goal of this article is to provide a pictorial essay of the perfusion CT features of diseases that affect brain perfusion as depicted in a population of children who were evaluated in the emergency CT unit of our institution...
  75. ncbi Admission perfusion CT: prognostic value in patients with severe head trauma
    Max Wintermark
    Department of Diagnostic and Interventional Radiology, Surgical Intensive Care Unit, University Hospital, 1011 Lausanne, Switzerland
    Radiology 232:211-20. 2004
    ..To assess the prognostic value of admission perfusion computed tomography (CT) in patients with severe head trauma...
  76. ncbi Relationship between brain perfusion computed tomography variables and cerebral perfusion pressure in severe head trauma patients
    Max Wintermark
    Department of Diagnostic and Interventional Radiology, University Hospital, Lausanne, Switzerland
    Crit Care Med 32:1579-87. 2004
    ..It might allow clinicians to distinguish between patients with preserved auto-regulation (or pseudoautoregulation) and those with impaired autoregulation and could therefore guide interpretation of CPP measurements and therapy...
  77. ncbi Traumatic injuries: organization and ergonomics of imaging in the emergency environment
    Max Wintermark
    Department of Diagnostic and Interventional Radiology, University Hospital, CHUV BH10, 1011 Lausanne, Switzerland
    Eur Radiol 12:959-68. 2002
    ..Trauma radiology and emergency radiology on the whole will assert themselves as consistent and thorough areas of subspecialization...
  78. ncbi Cerebral blood flow thresholds in acute stroke triage
    Michael H Lev
    Stroke 37:2202; author reply 2203. 2006
  79. ncbi Spinal arterial anatomy and risk factors for lower extremity weakness following endovascular thoracoabdominal aortic aneurysm repair with branched stent-grafts
    Catherine K Chang
    Department of Surgery, Division of Vascular Surgery, University of California at San Francisco, CA 94143 0222, USA
    J Endovasc Ther 15:356-62. 2008
    ..To evaluate spinal arterial anatomy and identify risk factors for lower extremity weakness (LEW) following endovascular thoracoabdominal aortic aneurysm (TAAA) repair...
  80. ncbi Thoracolumbar spine fractures in patients who have sustained severe trauma: depiction with multi-detector row CT
    Max Wintermark
    Department of Diagnostic and Interventional Radiology, Centre Hospitalier Universitaire Vaudois, BH07, 1011 Lausanne, Switzerland
    Radiology 227:681-9. 2003
    ..To determine if multi-detector row computed tomography (CT) can replace conventional radiography and be performed alone in severe trauma patients for the depiction of thoracolumbar spine fractures...
  81. ncbi Traumatic injuries: role of imaging in the management of the polytrauma victim (conservative expectation)
    Pierre-Alexandre Poletti
    Division of Diagnostic and Interventional Radiology, Geneva University Hospital, 24, rue Micheli-du-Crest, 1211 Geneva, Switzerland
    Eur Radiol 12:969-78. 2002
    ..g., posttraumatic biloma or bowel devascularization. Catheter angiography may be reserved to selected cases with vascular injuries proven on CT...
  82. ncbi Intraluminal aortic fat as an unusual presentation of blunt traumatic aortic rupture
    Max Wintermark
    Department of Diagnostic and Interventional Radiology, University Hospital, Lausanne, Switzerland
    J Trauma 52:1222. 2002
  83. ncbi MR pattern of hyperacute cerebral hemorrhage
    Max Wintermark
    Department of Diagnostic and Interventional Radiology, University Hospital, Lausanne, Switzerland
    J Magn Reson Imaging 15:705-9. 2002
    ..They constitute the earliest MR appearance of hyperacute intracerebral bleeding reported in the literature, featuring increased diffusion properties and persistent susceptibility effect on perfusion-weighted imaging (PWI)-series...
  84. ncbi Brain perfusion in children: evolution with age assessed by quantitative perfusion computed tomography
    Max Wintermark
    Department of Diagnostic and Interventional Radiology, University Hospital, Lausanne, Switzerland
    Pediatrics 113:1642-52. 2004
    ..The objective of this study was to assess the age-related variations of brain perfusion through quantitative cerebral perfusion computed tomography (CT) results in children without brain abnormality...
  85. ncbi Imaging of intracranial haemorrhage
    Chelsea S Kidwell
    Department of Neurology and Stroke Center, Georgetown University and Stroke Center, Washington Hospital Center, Washington, DC, USA
    Lancet Neurol 7:256-67. 2008
    ....

Research Grants1

  1. Advanced NeuroImaging for Acute Stroke Treatment
    Max Wintermark; Fiscal Year: 2007
    ..Invited junior scientists, for whom funding is requested, were selected based on merit. ..