Stuart S Winter
Affiliation: University of New Mexico
- Pediatric acute leukemia therapies informed by molecular analysis of high-risk diseaseStuart S Winter
Division of Pediatric Hematology Oncology, University of New Mexico, Albuquerque, NM 87131 5311, USA
Hematology Am Soc Hematol Educ Program 2011:366-73. 2011....
- Enhanced T-lineage acute lymphoblastic leukaemia cell survival on bone marrow stroma requires involvement of LFA-1 and ICAM-1S S Winter
Department of Paediatrics, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
Br J Haematol 115:862-71. 2001..This is the first report to demonstrate the importance of LFA-1/ICAM-1-mediated adhesion as a critical event in a cascade of cell surface receptor-ligand interactions that regulate T-ALL survival in the BM microenvironment...
- High-throughput screening for daunorubicin-mediated drug resistance identifies mometasone furoate as a novel ABCB1-reversal agentStuart S Winter
Pediatric Hematology Oncology, MSC 105590, University of New Mexico, Albuquerque, NM 87131 5311, USA
J Biomol Screen 13:185-93. 2008..In addition, the approach used in this study is useful for identifying off-patent drugs that may be repurposed for novel clinical indications...
- Identification of genomic classifiers that distinguish induction failure in T-lineage acute lymphoblastic leukemia: a report from the Children's Oncology GroupStuart S Winter
Department of Pediatrics, The University of New Mexico Health Sciences Center, Albuquerque, NM 87131 5311, USA
Blood 110:1429-38. 2007..Genetic profiling may identify T-ALL patients who are likely to fail induction and for whom alternate treatment strategies might be beneficial...
- Antimetabolite-based therapy in childhood T-cell acute lymphoblastic leukemia: a report of POG study 9296Stuart S Winter
Department of Pediatrics, Albuquerque, New Mexico 87131, USA
Pediatr Blood Cancer 46:179-86. 2006....
- High-throughput flow cytometry to detect selective inhibitors of ABCB1, ABCC1, and ABCG2 transportersIrena Ivnitski-Steele
Cytometry, Cancer Research and Treatment Center, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
Assay Drug Dev Technol 6:263-76. 2008....
- Genetic alterations determine chemotherapy resistance in childhood T-ALL: modelling in stage-specific cell lines and correlation with diagnostic patient samplesDavid A Estes
Department of Pathology, University of New Mexico Cancer Research and Treatment Center, Albuquerque, NM 87112, USA
Br J Haematol 139:20-30. 2007....
- Computerized system for outcomes-based antiemetic therapy in childrenM T Holdsworth
College of Pharmacy, University of New Mexico, Albuquerque 87131, USA
Ann Pharmacother 34:1101-8. 2000..To introduce a computerized data collection system used for an outcomes-based approach to antiemetic therapy in children, and to present data collected with this system in support of a new antiemetic dosing regimen...
- Enhanced leukemia cell detection using a novel magnetic needle and nanoparticlesJason E Jaetao
Department of Pathology, University of New Mexico and Cancer Research and Treatment Center, Albuquerque, New Mexico 87131, USA
Cancer Res 69:8310-6. 2009....
- Pain and distress from bone marrow aspirations and lumbar puncturesMark T Holdsworth
Pharmacy and Pediatrics, College of Pharmacy, University of New Mexico, Albuquerque, NM 87131 1066, USA
Ann Pharmacother 37:17-22. 2003..To compare the efficacy of 3 different pharmacologic regimens to relieve pain and distress in children with cancer undergoing bone marrow aspirations (BMAs) and lumbar punctures (LPs)...
- Risk determinants for catheter-associated blood stream infections in children and young adults with cancerRebekah C Allen
School of Medicine, University of New Mexico, Albuquerque, New Mexico, USA
Pediatr Blood Cancer 51:53-8. 2008..In order to understand which factors might predispose to CABSIs in children and young adults, we evaluated risk for infection in association with tumor type, catheter type, and setting of occurrence...
- Novel applications of recombinant factor VIIa for the management of pediatric coagulopathic diseasesPrasad Mathew
University of New Mexico, Department of Pediatrics, Pediatric Hematology Oncology, Albuquerque, New Mexico 87131 5311, USA
J Pediatr Hematol Oncol 25:499-502. 2003..Using laboratory and clinical measures of outcome, the use of rVIIa as a therapeutic option in treating several different pediatric coagulopathic conditions is described...
- Economic comparison of home-care-based versus hospital-based treatment of chemotherapy-induced febrile neutropenia in childrenDennis W Raisch
Veterans Affairs Cooperative Studies Program, Clinical Research Pharmacy Coordinating Center, Albuquerque, NM, USA
Value Health 6:158-66. 2003..The purpose of this study was to compare health-care resource utilization and outcomes among children treated for low-risk febrile neutropenia (FN) in a hospital-based setting with those treated in a home-care-based setting...
- Bone marrow stroma-supported culture of T-lineage acute lymphoblastic leukemic cells predicts treatment outcome in children: a Pediatric Oncology Group studyS S Winter
University of New Mexico Health Sciences Center, Department of Pediatrics, Albuquerque, NM, USA
Leukemia 16:1121-6. 2002..A prospective study is needed to test whether stroma-supported leukemic cell recovery might serve as a basis for assigning risk-adjusted therapy...
- Is prolonged stem cell mobilization detrimental for hematopoiesis?Alexandre Chigaev
Department of Pathology and Cancer Center, University of New Mexico, Albuquerque, NM 87131, United States
Med Hypotheses 77:1111-3. 2011..Furthermore, we also postulate that such cytopenias are caused by a loss of the niche environment, which is known to be essential for stem cell maintenance...
- Differential expression of Ikaros isoforms in monozygotic twins with MLL-rearranged precursor-B acute lymphoblastic leukemiaThomas Russell
Department of Pediatrics, University of New Mexico Health Sciences Center and Cancer Research and Treatment Center, Albuquerque, NM, USA
J Pediatr Hematol Oncol 30:941-4. 2008..Further exploration of Ikaros expression in the background of MLL rearrangements may provide new insights into disease pathogenesis and could offer targets for novel chemotherapeutic agents...
- Risk for leukemia in infants without Down syndrome who have transient myeloproliferative disorderThomas Cushing
Department of Pediatrics, Division of Genetics and Metabolism, Stanford University Medical Center, Stanford, California, USA
J Pediatr 148:687-9. 2006..We recommend that nondysmorphic infants with TMD undergo chromosome analysis for trisomy 21 and testing for GATA1 mutations to aid surveillance for leukemic transformation...
- Clinical manifestations of hemoglobin Chico at high altitudeCindi R Starkey
Department of Pathology, The University of New Mexico, Albuquerque, NM, USA
J Pediatr Hematol Oncol 28:760-2. 2006..At 16 years of age, he had mild anemia and a decreased pulse oximetry (83%) but sufficient pulmonary reserve to participate in physically demanding activities...
- Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemiaTeresa Palomero
Institute for Cancer Genetics, Columbia University, 1150 St Nicholas Ave, New York, NY 10032, USA
Blood 108:986-92. 2006..Our results indicate that TAL1 may act as a bifunctional transcriptional regulator (activator and repressor) at the top of a complex regulatory network that disrupts normal T-cell homeostasis and contributes to leukemogenesis...
- Rasburicase for the management of tumor lysis syndrome in neonatesDeborah M McNutt
University of Maryland, Baltimore, USA
Ann Pharmacother 40:1445-50. 2006..However, in instances of spontaneous TLS complicated by the normally low glomerular filtration rate in the newborn infant, the use of rasburicase and other supportive care measures may still be inadequate, warranting further study...