Research Topics
| Carolee WinsteinSummaryAffiliation: University of Southern California Country: USA Publications
Research Grants
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Detail Information
Publications
Hemispheric specialization in the co-ordination of arm and trunk movements during pointing in patients with unilateral brain damageDanilo Y Esparza
Neurological Science Research Centre, , Montreal, Quebec, Canada
Exp Brain Res 148:488-97. 2003....
Contextual interference effect: elaborative processing or forgetting-reconstruction? A post hoc analysis of transcranial magnetic stimulation-induced effects on motor learningChien Ho Janice Lin
Division of Biokinesiology and Physical Therapy, School of Dentistry, University of Southern California, Los Angeles 90033, USA
J Mot Behav 40:578-86. 2008..Unlike the prediction of the forgetting-reconstruction hypothesis, adding perturbation during Blocked Practice did not significantly enhance motor learning...- The mirror neuron system: a neural substrate for methods in stroke rehabilitationKathleen A Garrison
Motor Behavior and Neurorehabilitation Laboratory, Division of Biokinesiology and Physical Therapy, Brain and Creativity Institute, University of Southern California, Los Angeles, CA 90089 9006, USA
Neurorehabil Neural Repair 24:404-12. 2010..Here the authors review research into each condition of practice, and discuss the relevance of the mirror neuron system to stroke recovery... 
Planning and adjustments for the control of reach extent in a virtual environmentJill Campbell Stewart
Division of Biokinesiology and Physical Therapy at the School of Dentistry, University of Southern California, 1540 Alcazar Street, CHP 155, Los Angeles, CA 90089 9006, USA
J Neuroeng Rehabil 10:27. 2013..The purpose of this study was to directly compare the use of planning and adjustments to control extent for unconstrained reach actions performed in an immersive VE to those performed in an analogous real-world environment (RWE)...- Interdisciplinary Comprehensive Arm Rehabilitation Evaluation (ICARE): a randomized controlled trial protocolCarolee J Winstein
Division of Biokinesiology and Physical Therapy, Herman Ostrow School of Dentistry University of Southern California, Los Angeles, CA, USA
BMC Neurol 13:5. 2013..Two secondary objectives are to compare ASAP to a true (active monitoring only) usual and customary (UCC) therapy group and to compare DEUCC and UCC... - Intervention to enhance skilled arm and hand movements after stroke: A feasibility study using a new virtual reality systemJill Campbell Stewart
Division of Biokinesiology and Physical Therapy at the School of Dentistry, University of Southern California, Los Angeles, CA, USA
J Neuroeng Rehabil 4:21. 2007..We describe four VR tasks that were developed and tested to improve arm and hand movement skills for individuals with hemiparesis... - Socially assistive robotics for post-stroke rehabilitationMaja J Matarić
Computer Science Department, University of Southern California, Los Angeles, CA, USA
J Neuroeng Rehabil 4:5. 2007..We demonstrate the approach with an implemented and tested post-stroke recovery robot and discuss its potential for effectiveness... - Pediatric endurance and limb strengthening for children with cerebral palsy (PEDALS)--a randomized controlled trial protocol for a stationary cycling interventionEileen G Fowler
Department of Orthopedics, UCLA Orthopaedic Hospital Center for Cerebral Palsy, Los Angeles, CA, USA
BMC Pediatr 7:14. 2007..However, few studies have examined the potential benefits of cardiorespiratory fitness exercises in this patient population... - The immediate and long-term effects of exercise and patient education on physical, functional, and quality-of-life outcome measures after single-level lumbar microdiscectomy: a randomized controlled trial protocolDavid M Selkowitz
Department of Physical Therapy Education, Western University of Health Sciences, 309 E Second St, Pomona, CA 91766, USA
BMC Musculoskelet Disord 7:70. 2006.... - Does the cholinesterase inhibitor, donepezil, benefit both declarative and non-declarative processes in mild to moderate Alzheimer's disease?Carolee J Winstein
University of Southern California, Los Angeles, CA 90089 9006, USA
Curr Alzheimer Res 4:273-6. 2007..When the data were examined for coincidental changes in the two outcome measures together they are suggestive of a benefit from donepezil treatment for non-declarative and declarative processes... - Methods for a multisite randomized trial to investigate the effect of constraint-induced movement therapy in improving upper extremity function among adults recovering from a cerebrovascular strokeCarolee J Winstein
Department of Biokinesiology and Physical Therapy, University of Southern California, 1540 E Alcazar Street, CHP 155, Los Angeles, CA 90089 9006, USA
Neurorehabil Neural Repair 17:137-52. 2003..Secondary outcomes concern function, behavior, and compliance. This is the first multisite, single-blind RCT of a formal training intervention for upper extremity rehabilitation in subacute stroke in the United States... - The best we can be is yet to comeCarolee J Winstein
Division of Biokinesiology and Physical Therapy at the School of Dentistry, University of Southern California, Los Angeles, CA 90033, USA
Phys Ther 89:1236-49. 2009..She was elected a Catherine Worthingham Fellow in 2003... - A randomized controlled comparison of upper-extremity rehabilitation strategies in acute stroke: A pilot study of immediate and long-term outcomesCarolee J Winstein
Dept of Biokinesiology and Physical Therapy, University of Southern California, Health Sciences Campus, 1540 E Alcazar St, CHP 155, Los Angeles, CA 90089 9006, USA
Arch Phys Med Rehabil 85:620-8. 2004..To evaluate the immediate and long-term effects of 2 upper-extremity rehabilitation approaches for stroke compared with standard care in participants stratified by stroke severity... - Neural correlate of the contextual interference effect in motor learning: a kinematic analysisChien Ho Janice Lin
School of Dentistry, University of Southern California, Los Angeles, CA, USA
J Mot Behav 41:232-42. 2009..The authors' data suggest that increased corticomotor activity during high CI practice may reflect preferential processing of the temporal parameter of the task... - Hemisphere specific impairments in reach-to-grasp control after stroke: effects of object sizeJarugool Tretriluxana
Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, Department of Neurology, Keck School of Medicine, Los Angeles, CA 90033, USA
Neurorehabil Neural Repair 23:679-91. 2009..Based on a bilateral model, the authors hypothesized that after unilateral stroke there would be hemisphere-specific deficits revealed by the ipsilesional limb... - Manual asymmetries in grasp pre-shaping and transport-grasp coordinationJarugool Tretriluxana
Division of Biokinesiology and Physical Therapy, University of Southern California, 1540 East Alcazar Street CHP155, Los Angeles, CA 90033, USA
Exp Brain Res 188:305-15. 2008..Our findings compliment the specialization previously observed for pointing movements of the dominant and non-dominant hemispheric/limb system and the coordinated control of complex movements and visuo-spatial components, respectively... - Socially assistive robotics for stroke and mild TBI rehabilitationMaja Mataric
Department of Computer Science, University of Southern California, Los Angeles, USA
Stud Health Technol Inform 145:249-62. 2009.... - Effects of task-specific locomotor and strength training in adults who were ambulatory after stroke: results of the STEPS randomized clinical trialKatherine J Sullivan
Division of Biokinesiology and Physical Therapy at the School of Dentistry, University of Southern California, 1540 E Alcazar St, CHP 155, Los Angeles, CA 90089, USA
Phys Ther 87:1580-602. 2007..A phase II, single-blinded, randomized clinical trial was conducted to determine the effects of combined task-specific and lower-extremity (LE) strength training to improve walking ability after stroke... - An intensive, progressive exercise program reduces disability and improves functional performance in patients after single-level lumbar microdiskectomyKornelia Kulig
Division of Biokinesiology and Physical Therapy, University of Southern California, 1540 E Alcazar St, CHP 155, Los Angeles, CA 90089 9006, USA
Phys Ther 89:1145-57. 2009..Restoration of physical function following lumbar microdiskectomy may be influenced by the postoperative care provided... - A functional threshold for long-term use of hand and arm function can be determined: predictions from a computational model and supporting data from the Extremity Constraint-Induced Therapy Evaluation (EXCITE) TrialNicolas Schweighofer
Division of Biokinesiology and Physical Therapy at the School of Dentistry, and Department of Computer Science, University of Southern California, Los Angeles, CA 90089, USA
Phys Ther 89:1327-36. 2009..A previous neurocomputational model predicted that if the dose of therapy is sufficient to bring performance above a certain threshold, training can be stopped... - Effect of task practice order on motor skill learning in adults with Parkinson disease: a pilot studyChien Ho Janice Lin
School of Dentistry, University of Southern California, Los Angeles, CA 90089, USA
Phys Ther 87:1120-31. 2007..Random practice of motor tasks has been shown to enhance motor learning. The purpose of this study was to investigate the effects of task practice order (random, blocked) on motor learning in adults with Parkinson disease (PD)... - Virtual reality applications for addressing the needs of those aging with disabilityAlbert Rizzo
University of Southern California, Institute for Creative Technologies, Playa Vista, CA 90064, USA
Stud Health Technol Inform 163:510-6. 2011..This is the theme of the research to be presented at this MMVR workshop... - Neural correlates of the contextual interference effect in motor learning: a transcranial magnetic stimulation investigationChien Ho Janice Lin
Division of Biokinesiology and Physical Therapy, School of Dentistry, University of Southern California, Los Angeles, CA, USA
J Mot Behav 42:223-32. 2010..Results contribute to knowledge of the critical and specific role that M1 plays in generating a learning advantage following high-interference practice conditions... - Motor cortex activation during treatment may predict therapeutic gains in paretic hand function after strokeYun Dong
Department of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA, USA
Stroke 37:1552-5. 2006..CONCLUSIONS: The relationship between brain activation during treatment and functional gains suggests a use for serial fMRI in predicting the success and optimal duration for a focused therapeutic intervention... - A systematic review of voluntary arm recovery in hemiparetic stroke: critical predictors for meaningful outcomes using the international classification of functioning, disability, and healthShu Ya Chen
Division of Biokinesiology and Physical Therapy, School of Dentistry, University of Southern California, Los Angeles, California, USA
J Neurol Phys Ther 33:2-13. 2009.... - Evolution of FMRI activation in the perilesional primary motor cortex and cerebellum with rehabilitation training-related motor gains after stroke: a pilot studyYun Dong
Department of Neurology, University of California at Los Angeles, Los Angeles, CA 90095 1769, USA
Neurorehabil Neural Repair 21:412-28. 2007..Previous studies report that motor recovery after partial destruction of the primary motor cortex (M1) may be associated with adaptive functional reorganization within spared M1... - Bimanual training after stroke: are two hands better than one?Dorian K Rose
Department of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, California, USA
Top Stroke Rehabil 11:20-30. 2004..Based on our review, we suggest a set of prerequisite task features and patient characteristics for consideration in the application of bimanual training protocols for poststroke rehabilitation... - Neural substrates of motor memory consolidation depend on practice structureShailesh S Kantak
Motor Behavior and Neurorehabilitation Laboratory, Division of Biokinesiology and Physical Therapy at the Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, California, USA
Nat Neurosci 13:923-5. 2010..We conclude that neural substrates of motor-memory consolidation are modulated by practice structure... - Impact of explicit information on implicit motor-sequence learning following middle cerebral artery strokeLara A Boyd
Department of Physical Therapy and Rehabilitation Sciences, University of Kansas Medical Center, 3056 Robinson, Mail Stop 2002, 3901 Rainbow Blvd, Kansas City, KS 66160 7601, USA
Phys Ther 83:976-89. 2003..The purpose of this work was to systematically investigate the impact of explicit information (EI) on implicit motor-sequence learning using the ipsilesional arm in people with damage in the middle cerebral artery (MCA) distribution... - Learning implicitly: effects of task and severity after strokeLara A Boyd
School of Rehabilitation Sciences, University of British Columbia, Vancouver, British Columbia, Canada
Neurorehabil Neural Repair 21:444-54. 2007 - Retention of upper limb function in stroke survivors who have received constraint-induced movement therapy: the EXCITE randomised trialSteven L Wolf
Department of Rehabilitation Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Lancet Neurol 7:33-40. 2008..The EXCITE trial has previously shown the efficacy of this intervention for patients 3-9 months poststroke who were followed-up for the next 12 months. We assessed the retention of improvements 24 months after the intervention... - Providing explicit information disrupts implicit motor learning after basal ganglia strokeLara A Boyd
Department of Physical Therapy and Rehabilitation Sciences, Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
Learn Mem 11:388-96. 2004..This may be due to the increased demand placed on working memory by explicit information. Thus, basal ganglia integrity may be a crucial factor in determining the efficacy of explicit information for implicit motor-sequence learning... - Cerebellar stroke impairs temporal but not spatial accuracy during implicit motor learningLara A Boyd
Department of Physical Therapy and Rehabilitation Sciences, University of Kansas Medical Center, 3056 Robinson, Mail Stop 2002, 3901 Rainbow Boulevard, Kansas City 66160 7601, USA
Neurorehabil Neural Repair 18:134-43. 2004..The purpose of this study was to determine if specific components (spatial or temporal) of an implicit motor-tracking task were affected by cerebellar stroke... - The EXCITE trial: attributes of the Wolf Motor Function Test in patients with subacute strokeSteven L Wolf
Department of Rehabilitation Medicine, Emory University School of Medicine, Atlanta, GA 30345, USA
Neurorehabil Neural Repair 19:194-205. 2005..The WMFT discriminates higher from lower functioning participants tested across research sites. Comparable findings using the FMA support the criterion validity of the WMFT... - Determining the optimal challenge point for motor skill learning in adults with moderately severe Parkinson's diseaseSomporn Onla-or
Department of Physical Therapy, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand
Neurorehabil Neural Repair 22:385-95. 2008..To test the predictions of the Challenge Point Framework (CPF) for motor learning in individuals with Parkinson's disease (PD) by manipulating nominal task difficulty and conditions of practice... - Effect of constraint-induced movement therapy on upper extremity function 3 to 9 months after stroke: the EXCITE randomized clinical trialSteven L Wolf
Department of Rehabilitation Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
JAMA 296:2095-104. 2006.... - Reliability of intracortical and corticomotor excitability estimates obtained from the upper extremities in chronic strokeLisa Koski
Division of Geriatrics, Faculty of Medicine, Department of Neurology and Neurosurgery, McGill University, Canada
Neurosci Res 58:19-31. 2007..Due to high intrasubject variability, the use of some excitability parameters as indicators of functional neuroplasticity in response to treatment may be limited to interventions with large effect sizes... - The Excite Trial: relationship of intensity of constraint induced movement therapy to improvement in the wolf motor function testSteven L Wolf
Department of Rehabilitation Medicine, Division of Physical Therapy, Emory University School of Medicine, Atlanta, GA 30322, USA
Restor Neurol Neurosci 25:549-62. 2007..To examine the relationship between change scores on the log mean Wolf Motor Function Test (lmWMFT) and the intensity of supervised Constraint Induced Movement Therapy (CIMT) in participants with subacute and chronic stroke...
Research Grants
- CI Therapy and Novel Virtual EnvironmentsCarolee Winstein; Fiscal Year: 2005..Phase II will establish a broader application in the clinical environment, incorporate patient perspectives, and longer-term outcomes. ..
- Brain and Behavior Correlates of Arm RehabilitationCarolee Winstein; Fiscal Year: 2004..abstract_text> ..