Affiliation: University of Colorado Denver
- Siglec-6 is expressed in gestational trophoblastic disease and affects proliferation, apoptosis and invasionKristen K Rumer
Department of Obstetrics and Gynecology, University of Colorado School of Medicine, MS8613, P15 3009, 12700 East 19th Avenue, Aurora, Colorado 80045, USA
Endocr Relat Cancer 19:827-40. 2012..We propose that Siglec-6 and leptin play a role in the aberrant properties characteristic of GTD, namely excess proliferation and invasion...
- Severe preeclampsia-related changes in gene expression at the maternal-fetal interface include sialic acid-binding immunoglobulin-like lectin-6 and pappalysin-2Virginia D Winn
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, San Francisco, California 94143, USA
Endocrinology 150:452-62. 2009..The functional significance of these novel observations may provide new insights into the pathogenesis of PE, and assaying the circulating levels of these proteins could have clinical utility for predicting and/or diagnosing PE...
- Functional significance of Siglec-6, a novel leptin receptor, in human placentalVirginia Winn; Fiscal Year: 2010..For the baby, PE can cause growth failure or stillbirth. Those babies that do survive have an increased risk of disorders as adults including diabetes and heart disease. ..