John R Wingard

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi request reprint Pharmacoeconomic analysis of caspofungin versus liposomal amphotericin B as empirical antifungal therapy for neutropenic fever
    John R Wingard
    Division of Hematology and Oncology, College of Medicine, University of Florida Shands Cancer Center, Gainesville, Florida 32610 0277, USA
    Am J Health Syst Pharm 64:637-43. 2007
  2. ncbi request reprint Interleukin 12 is associated with reduced relapse without increased incidence of graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
    Vijay Reddy
    Division of Hematology Oncology, College of Medicine, University of Florida, Gainesville, Florida 32610, USA
    Biol Blood Marrow Transplant 11:1014-21. 2005
  3. ncbi request reprint Sites and kinetics of donor thrombopoiesis following transplantation of whole bone marrow and progenitor subsets
    Xiao Miao Li
    Department of Pediatrics, University of Florida, Gainesville, USA
    Exp Hematol 35:1567-79. 2007
  4. pmc Have novel serum markers supplanted tissue diagnosis for invasive fungal infections in acute leukemia and transplantation?
    John R Wingard
    Division of Hematology Oncology, University of Florida College of Medicine, P O Box 103633, 2033 Mowry Road, Suite 145, Gainesville, FL 32610 3633, USA
    Best Pract Res Clin Haematol 25:487-91. 2012
  5. doi request reprint How I manage pulmonary nodular lesions and nodular infiltrates in patients with hematologic malignancies or undergoing hematopoietic cell transplantation
    John R Wingard
    Division of Hematology, University of Florida College of Medicine, Gainesville, FL 32610 0278, USA
    Blood 120:1791-800. 2012
  6. pmc Long-term survival and late deaths after allogeneic hematopoietic cell transplantation
    John R Wingard
    Shands Hospital, University of Florida, College of Medicine, Gainesville, FL 32610 0278, USA
    J Clin Oncol 29:2230-9. 2011
  7. doi request reprint Hematopoietic stem cell transplantation: an overview of infection risks and epidemiology
    John R Wingard
    Division of Hematology Oncology, University of Florida College of Medicine, PO Box 100278, 1600 SW Archer Road, Gainesville, FL 32610 0278, USA
    Infect Dis Clin North Am 24:257-72. 2010
  8. doi request reprint Use of antibacterial prophylaxis in patients with chemotherapy-induced neutropenia
    John R Wingard
    Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
    Curr Opin Hematol 19:21-6. 2012
  9. pmc Factors associated with self-reported physical and mental health after hematopoietic cell transplantation
    John R Wingard
    Department of Medicine, University of Florida College of Medicine, 1600 SW Archer Road, Gainesville, FL 32610 0278, USA
    Biol Blood Marrow Transplant 16:1682-92. 2010
  10. doi request reprint Serum IgG responses against Aspergillus proteins before hematopoietic stem cell transplantation or chemotherapy identify patients who develop invasive aspergillosis
    Chen Du
    Department of Medicine, University of Pittsburgh, Pennsylvania, USA
    Biol Blood Marrow Transplant 18:1927-34. 2012

Detail Information

Publications66

  1. ncbi request reprint Pharmacoeconomic analysis of caspofungin versus liposomal amphotericin B as empirical antifungal therapy for neutropenic fever
    John R Wingard
    Division of Hematology and Oncology, College of Medicine, University of Florida Shands Cancer Center, Gainesville, Florida 32610 0277, USA
    Am J Health Syst Pharm 64:637-43. 2007
    ..An analysis was conducted that evaluated and compared the cost differences between caspofungin and liposomal amphotericin B when the medications were used as empirical antifungal therapy for persistent fever during neutropenia...
  2. ncbi request reprint Interleukin 12 is associated with reduced relapse without increased incidence of graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
    Vijay Reddy
    Division of Hematology Oncology, College of Medicine, University of Florida, Gainesville, Florida 32610, USA
    Biol Blood Marrow Transplant 11:1014-21. 2005
    ..Patients with high pretransplantation IL-12 levels have an increased likelihood of higher posttransplantation IL-12 levels, possibly because of a host-graft interaction, and this may predispose to better clinical outcomes...
  3. ncbi request reprint Sites and kinetics of donor thrombopoiesis following transplantation of whole bone marrow and progenitor subsets
    Xiao Miao Li
    Department of Pediatrics, University of Florida, Gainesville, USA
    Exp Hematol 35:1567-79. 2007
    ..The spleen is a site of hematopoiesis in a healthy mouse, and hematopoietic activity increases in response to stress. We hypothesized that the spleen is a major site of early post-transplant thrombopoiesis...
  4. pmc Have novel serum markers supplanted tissue diagnosis for invasive fungal infections in acute leukemia and transplantation?
    John R Wingard
    Division of Hematology Oncology, University of Florida College of Medicine, P O Box 103633, 2033 Mowry Road, Suite 145, Gainesville, FL 32610 3633, USA
    Best Pract Res Clin Haematol 25:487-91. 2012
    ..Improved survival rates from aspergillosis are, in part, due to earlier detection of infection and earlier therapy...
  5. doi request reprint How I manage pulmonary nodular lesions and nodular infiltrates in patients with hematologic malignancies or undergoing hematopoietic cell transplantation
    John R Wingard
    Division of Hematology, University of Florida College of Medicine, Gainesville, FL 32610 0278, USA
    Blood 120:1791-800. 2012
    ..Interdisciplinary teamwork is highly desirable to optimize diagnosis and therapy...
  6. pmc Long-term survival and late deaths after allogeneic hematopoietic cell transplantation
    John R Wingard
    Shands Hospital, University of Florida, College of Medicine, Gainesville, FL 32610 0278, USA
    J Clin Oncol 29:2230-9. 2011
    ..Most deaths occur within the first 2 years after transplantation. In this report, we examine long-term survival in 2-year survivors in the largest cohort ever studied...
  7. doi request reprint Hematopoietic stem cell transplantation: an overview of infection risks and epidemiology
    John R Wingard
    Division of Hematology Oncology, University of Florida College of Medicine, PO Box 100278, 1600 SW Archer Road, Gainesville, FL 32610 0278, USA
    Infect Dis Clin North Am 24:257-72. 2010
    ..Over time, with strengthening immune reconstitution and control of graft-versus-host disease, the risk for infection dissipates...
  8. doi request reprint Use of antibacterial prophylaxis in patients with chemotherapy-induced neutropenia
    John R Wingard
    Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
    Curr Opin Hematol 19:21-6. 2012
    ..However, concerns about the potential emergence of antibiotic resistance have led to multiple recent studies exploring this issue...
  9. pmc Factors associated with self-reported physical and mental health after hematopoietic cell transplantation
    John R Wingard
    Department of Medicine, University of Florida College of Medicine, 1600 SW Archer Road, Gainesville, FL 32610 0278, USA
    Biol Blood Marrow Transplant 16:1682-92. 2010
    ..These observations provide insight into the identification of factors that can allow recognition of at-risk patients, as well as factors amenable to intervention...
  10. doi request reprint Serum IgG responses against Aspergillus proteins before hematopoietic stem cell transplantation or chemotherapy identify patients who develop invasive aspergillosis
    Chen Du
    Department of Medicine, University of Pittsburgh, Pennsylvania, USA
    Biol Blood Marrow Transplant 18:1927-34. 2012
    ..Our data suggest that some patients with IA have significant colonization or ongoing Aspergillus infections before immunosuppression. As such, IA may reflect unique predispositions to infection and/or progression from endogenous sources...
  11. pmc Use of bronchoalveolar lavage to detect galactomannan for diagnosis of pulmonary aspergillosis among nonimmunocompromised hosts
    M Hong Nguyen
    Department of Medicine, University of Florida College of Medicine, Gainesville, Florida 32610, USA
    J Clin Microbiol 45:2787-92. 2007
    ..Given the likelihood of false-positive results, a BAL GM test should not be ordered routinely in this population...
  12. ncbi request reprint Prevention and early treatment of invasive fungal infection in patients with cancer and neutropenia and in stem cell transplant recipients in the era of newer broad-spectrum antifungal agents and diagnostic adjuncts
    Brahm H Segal
    Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Clin Infect Dis 44:402-9. 2007
    ..Finally, we discuss the implications of newer antifungal agents and diagnostic adjuncts in the design of future clinical trials to evaluate prophylaxis and early prevention strategies...
  13. pmc Relationship of race/ethnicity and survival after single umbilical cord blood transplantation for adults and children with leukemia and myelodysplastic syndromes
    Karen K Ballen
    Division of Hematology Oncology, Massachusetts General Hospital, Boston, MA 02114, USA
    Biol Blood Marrow Transplant 18:903-12. 2012
    ..These results suggest that blacks have inferior survival to whites after single UCBT, but outcomes are improved when units with a higher cell dose are used...
  14. doi request reprint Changes in causes of death over time after treatment for invasive aspergillosis
    John R Wingard
    Department of Medicine, University of Florida College of Medicine, Gainesville, Florida 32610 3633, USA
    Cancer 112:2309-12. 2008
    ..Assessment of response to invasive aspergillosis (IA) therapy has been challenging in treatment trials...
  15. pmc Randomized, double-blind trial of fluconazole versus voriconazole for prevention of invasive fungal infection after allogeneic hematopoietic cell transplantation
    John R Wingard
    University of Florida, Gainesville, FL, USA
    Blood 116:5111-8. 2010
    ..This trial was registered at www.clinicaltrials.gov as NCT00075803...
  16. doi request reprint Bone marrow sinusoidal endothelial cells undergo nonapoptotic cell death and are replaced by proliferating sinusoidal cells in situ to maintain the vascular niche following lethal irradiation
    Xiao Miao Li
    Department of Pediatrics, University of Florida, Gainesville, FL 32610, USA
    Exp Hematol 36:1143-1156. 2008
    ..Bone marrow sinusoids remain predominantly host-derived following bone marrow transplantation. Systematic analysis was conducted at the cellular level to investigate how the host sinusoidal structures survived after lethal irradiation...
  17. ncbi request reprint Late effects of cancer and hematopoietic stem-cell transplantation on spouses or partners compared with survivors and survivor-matched controls
    Michelle M Bishop
    Department of Medicine, University of Florida College of Medicine, Gainesville, FL 32610 0277, USA
    J Clin Oncol 25:1403-11. 2007
    ..The purpose of this study was to examine the health-related quality of life and post-traumatic growth (PTG) of spouses/partners compared with survivors and controls and to identify factors associated with those outcomes...
  18. pmc The preventive health behaviors of long-term survivors of cancer and hematopoietic stem cell transplantation compared with matched controls
    Michelle M Bishop
    Department of Medicine, University of Florida College of Medicine, Gainesville, Florida 32610 0277, USA
    Biol Blood Marrow Transplant 16:207-14. 2010
    ..There remains considerable room for improvement. These findings support the need for further education of both HCT survivors and health practitioners...
  19. pmc Autologous umbilical cord blood infusion followed by oral docosahexaenoic acid and vitamin D supplementation for C-peptide preservation in children with Type 1 diabetes
    Michael J Haller
    Department of Pediatrics, The University of Florida, Gainesville, FL 32610, USA
    Biol Blood Marrow Transplant 19:1126-9. 2013
    ..Lack of significance may reflect small sample size. Future efforts will require expansion of specific immunoregulatory cell subsets, optimization of combined immunoregulatory and anti-inflammatory agents, and larger study cohorts...
  20. ncbi request reprint Umbilical cord blood produces small megakaryocytes after transplantation
    Mark Ignatz
    Department of Pediatrics, University of Florida, Gainesville, Florida, USA
    Biol Blood Marrow Transplant 13:145-50. 2007
    ..For the first time, we demonstrate that the attainment of adult size in CB-derived megakaryocytes is delayed after human CB transplantation...
  21. doi request reprint Characteristics of thawed autologous umbilical cord blood
    Emma H Rosenau
    Department of Medicine, University of Florida, and Shands Hospital, University of Florida, Gainesville, Florida, USA
    Transfusion 52:2234-42. 2012
    ..Increasingly, private AutoUCB banking is performed for therapies unavailable today. A Phase I trial using AutoUCB treatment for early pediatric Type 1 diabetes afforded us an opportunity to analyze characteristics of AutoUCBs...
  22. ncbi request reprint New approaches to invasive fungal infections in acute leukemia and hematopoietic stem cell transplant patients
    John R Wingard
    Blood and Marrow Transplant Program, Division of Hematology Oncology, University of Florida Shands Cancer Center, 1376 Mowry Road, Room 145, Gainesville, FL 32610 3633, USA
    Best Pract Res Clin Haematol 20:99-107. 2007
    ..Combining the new diagnostic tools with new drugs, novel strategies are being evaluated to change our approaches to these deadly infections...
  23. ncbi request reprint The role of the donor in the repair of the marrow vascular niche following hematopoietic stem cell transplant
    William B Slayton
    University of Florida Program in Stem Cell Biology and Regenerative Medicine, Department of Pediatrics, University of Florida Health Science Center, Gainesville, Florida 32610, USA
    Stem Cells 25:2945-55. 2007
    ..Donor support for the repair of the marrow vascular niche may be a critical first step of hematopoietic engraftment...
  24. ncbi request reprint Increased levels of tumor necrosis factor alpha are associated with an increased risk of cytomegalovirus infection after allogeneic hematopoietic stem cell transplantation
    Vijay Reddy
    University of Florida College of Medicine, Gainesville, FL 32610, USA
    Biol Blood Marrow Transplant 11:698-705. 2005
    ..017). In conclusion, a high posttransplantation TNF level is significantly associated with the risk for developing CMV infection. Early detection of high levels of TNF may be used to identify patients at high risk for developing CMV-Ag...
  25. ncbi request reprint Strategy of following voriconazole versus amphotericin B therapy with other licensed antifungal therapy for primary treatment of invasive aspergillosis: impact of other therapies on outcome
    Thomas F Patterson
    Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
    Clin Infect Dis 41:1448-52. 2005
    ..In that trial, treatment with voriconazole or amphotericin B deoxycholate could be followed with other licensed antifungal therapies (OLAT). Here, we report the impact of OLAT on the outcome of patients with invasive aspergillosis...
  26. ncbi request reprint New strategies of antifungal therapy in hematopoietic stem cell transplant recipients and patients with hematological malignancies
    Helen L Leather
    Shands at the University of Florida, Gainesville, FL 32610 0316, USA
    Blood Rev 20:267-87. 2006
    ....
  27. ncbi request reprint Pharmacokinetic evaluation of the drug interaction between intravenous itraconazole and intravenous tacrolimus or intravenous cyclosporin A in allogeneic hematopoietic stem cell transplant recipients
    Helen Leather
    Shands at the University of Florida, Gainesville, Florida 32610 0316, USA
    Biol Blood Marrow Transplant 12:325-34. 2006
    ....
  28. pmc Autologous umbilical cord blood transfusion in young children with type 1 diabetes fails to preserve C-peptide
    Michael J Haller
    Department of Pediatrics, University of Florida, Gainesville, Florida, USA
    Diabetes Care 34:2567-9. 2011
    ..Having previously reported on the first 15 patients reaching 1 year of follow-up, herein we report on the complete cohort after 2 years of follow-up...
  29. ncbi request reprint Hypomethylating agent induction therapy followed by hematopoietic cell transplantation is feasible in patients with myelodysplastic syndromes
    Christopher R Cogle
    Division of Hematology and Oncology, University of Florida College of Medicine, Gainesville, FL 32610, USA
    Clin Adv Hematol Oncol 8:40-6. 2010
    ..Lineage analysis also found rapid donor chimerism of lymphocyte and granulocyte subsets. These data indicate the feasibility of pretransplant azanucleoside therapy in patients who subsequently receive an HCT...
  30. pmc Defining responses to therapy and study outcomes in clinical trials of invasive fungal diseases: Mycoses Study Group and European Organization for Research and Treatment of Cancer consensus criteria
    Brahm H Segal
    Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York 14263, USA
    Clin Infect Dis 47:674-83. 2008
    ..We also discuss potential pitfalls in assessing outcome, such as conflicting clinical, radiological, and/or mycological data and gaps in knowledge...
  31. ncbi request reprint Diagnostic strategies for invasive fungal infections in patients with hematologic malignancies and hematopoietic stem cell transplant recipients
    Maxim Norkin
    From the Division of Hematology Oncology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida
    J Natl Compr Canc Netw 11:941-9. 2013
    ..Recommendations are provided regarding effective use of these methodologies in clinical practice. ..
  32. doi request reprint Comparison of lasting life changes after cancer and BMT: perspectives of long-term survivors and spouses
    Michelle M Bishop
    Department of Medicine, Division of Hematology Oncology, University of Florida, FL 32610 0277, USA
    Psychooncology 20:926-34. 2011
    ....
  33. ncbi request reprint Design issues in a prospective randomized double-blinded trial of prophylaxis with fluconazole versus voriconazole after allogeneic hematopoietic cell transplantation
    John R Wingard
    Department of Medicine, Blood and Marrow Transplant Program, Division of Hematology Oncology, University of Florida Shands Cancer Center, Gainesville, FL 32610, USA
    Clin Infect Dis 39:S176-80. 2004
    ..About 15% of patients become infected, with a case fatality rate of approximately 65%. To date, no effective prophylactic strategies have been developed...
  34. ncbi request reprint Prophylaxis, empirical therapy, or pre-emptive therapy of fungal infections in immunocompromised patients: which is better for whom?
    Helen L Leather
    Department of Pharmacy, College of Medicine, University of Florida, Gainesville, Florida, USA
    Curr Opin Infect Dis 15:369-75. 2002
    ..Validations of the various techniques show promise and are reviewed in this paper...
  35. ncbi request reprint Low dendritic cell count after allogeneic hematopoietic stem cell transplantation predicts relapse, death, and acute graft-versus-host disease
    Vijay Reddy
    Division of Hematology Oncology, University of Florida College of Medicine, 1600 SW Archer Rd, Gainesville, FL 32610, USA
    Blood 103:4330-5. 2004
    ..Low numbers of circulating DCs significantly increase the risk for relapse and acute GVHD and predict death after allogeneic SCT...
  36. ncbi request reprint Caspofungin versus amphotericin B for candidemia: a pharmacoeconomic analysis
    John R Wingard
    University of Florida College of Medicine, Gainesville, 32610, USA
    Clin Ther 27:960-9. 2005
    ..7% and 62.8% of patients, respectively) and exhibited a generally better safety profile, particularly with respect to impaired renal function (IRF) (P = 0.02)...
  37. doi request reprint Current approaches in antifungal prophylaxis in high risk hematologic malignancy and hematopoietic stem cell transplant patients
    Baldeep Wirk
    Division of Hematology and Oncology, College of Medicine, Bone Marrow Transplant Program, University of Florida, 1600 SW Archer Road, PO Box 100277, Gainesville, FL 32610, USA
    Mycopathologia 168:299-311. 2009
    ..However, concerns about shifts in fungal epidemiology, emergence of resistance, drug toxicities, and drug interactions must be considered in deciding how and in whom to use antifungal prophylaxis...
  38. ncbi request reprint Influenza: preparedness for an inevitable "Emergency" for oncology and BMT units
    John R Wingard
    Division of Hematology Oncology, University of Florida College of Medicine, Gainesville, FL 32610 3633, USA
    J Natl Compr Canc Netw 6:215-22. 2008
    ..Ongoing engagement by the entire team to evaluate the effectiveness of its actions and modify its plan as necessary will ensure success...
  39. pmc Factors associated with mortality in transplant patients with invasive aspergillosis
    John W Baddley
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, AL 35294 0006, USA
    Clin Infect Dis 50:1559-67. 2010
    ..The purpose of this study was to evaluate factors associated with mortality in transplant patients with IA...
  40. pmc Bronchoalveolar lavage galactomannan in diagnosis of invasive pulmonary aspergillosis among solid-organ transplant recipients
    Cornelius J Clancy
    Department of Medicine, University of Florida College of Medicine, Gainesville, FL 32610, USA
    J Clin Microbiol 45:1759-65. 2007
    ..5%, respectively (cutoff, > or = 1.0). In conclusion, BAL GM testing facilitated more-rapid diagnoses of IPA and the institution of antifungal therapy among non-lung solid-organ transplant recipients and helped to rule out IPA...
  41. pmc Phase II trial of parathyroid hormone after double umbilical cord blood transplantation
    Karen Ballen
    Hematology Oncology Division, Department of Medicine, Massachusetts General Hospital, Boston, USA
    Biol Blood Marrow Transplant 18:1851-8. 2012
    ..Overall survival at 6 months after transplantation was 62%, and disease-free survival at 2 years was 39%. At the dose and schedule studied, there was no evidence that PTH influenced blood count recovery...
  42. ncbi request reprint Empirical antifungal therapy in treating febrile neutropenic patients
    John R Wingard
    Department of Medicine, Blood and Marrow Transplant Program, University of Florida Shands Cancer Center, Gainesville, Florisa 32610 0277, USA
    Clin Infect Dis 39:S38-43. 2004
    ..Newer diagnostic tools are needed to target those most in need of antifungal therapy...
  43. ncbi request reprint A new era of antifungal therapy
    John R Wingard
    Blood and Marrow Transplant Program, Division of Hematology Oncology, University of Florida Shands Cancer Center, Gainesville, USA
    Biol Blood Marrow Transplant 10:73-90. 2004
    ..It is hoped that these new therapies and new diagnostics will usher in a new era of antifungal therapy...
  44. ncbi request reprint Access to stem cell transplantation: do women fare as well as men?
    Paulette Mehta
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA
    Am J Hematol 72:99-102. 2003
    ..While boys with ALL appear to receive SCT at a higher rate, this difference is likely attributable to biological rather than social reasons...
  45. ncbi request reprint Developmental differences in megakaryocyte maturation are determined by the microenvironment
    William B Slayton
    University of Florida Department of Pediatrics, Gainesville, Florida 32610, USA
    Stem Cells 23:1400-8. 2005
    ..These differences may contribute to the delay in platelet engraftment that frequently complicates cord blood transplants...
  46. doi request reprint Quality of life, social challenges, and psychosocial support for long-term survivors after allogeneic hematopoietic stem-cell transplantation
    Maxim Norkin
    University of Florida College of Medicine, Gainesville, FL 32610 0278, USA
    Semin Hematol 49:104-9. 2012
    ..Currently, resources should be focused on how research findings can be used by patients, their partners, and physicians to optimize QoL and psychosocial adjustment...
  47. doi request reprint Spiritual absence and 1-year mortality after hematopoietic stem cell transplant
    Deidre B Pereira
    Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida 32610 0165, USA
    Biol Blood Marrow Transplant 16:1171-9. 2010
    ..Future research should examine these relations in a larger sample using a more comprehensive assessment of spirituality...
  48. ncbi request reprint Treatment of zygomycosis with posaconazole in a patient with acute myeloid leukemia
    Helen L Leather
    University of Florida, Gainesville, 32610, USA
    Clin Adv Hematol Oncol 3:773-7. 2005
  49. doi request reprint Strategies for minimizing complications of neutropenia: prophylactic myeloid growth factors or antibiotics
    John R Wingard
    Division of Hematology Oncology, University of Florida College of Medicine, P O Box 103633, 1376 Mowry Road, Gainesville, FL 32610 3633, USA
    Crit Rev Oncol Hematol 72:144-54. 2009
    ..Each type of prophylaxis has advantages and disadvantages. Additional studies are needed to optimize how these are employed in clinical practice...
  50. doi request reprint Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 Update by the Infectious Diseases Society of America
    Alison G Freifeld
    Department of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA
    Clin Infect Dis 52:427-31. 2011
    ..Regardless of venue, clinical vigilance and immediate treatment are the universal keys to managing neutropenic patients with fever and/or infection...
  51. pmc Immunoglobulin G responses to a panel of Candida albicans antigens as accurate and early markers for the presence of systemic candidiasis
    Cornelius J Clancy
    Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
    J Clin Microbiol 46:1647-54. 2008
    ..Taken together, our findings suggest that IgG responses against a panel of candidal antigens might represent an accurate and early marker of systemic candidiasis, a hypothesis that should be tested in future trials...
  52. ncbi request reprint Is combination antifungal therapy for invasive aspergillosis a necessity in hematopoietic stem-cell transplant recipients?
    Helen L Leather
    Shands Healthcare at the University of Florida, 32610 0316, USA
    Curr Opin Infect Dis 19:371-9. 2006
    ..The recent literature is reviewed and the relative arguments for and against combination antifungal therapy are outlined with summative recommendations to assist practitioners in decision-making...
  53. pmc Diagnostic methods for invasive fungal diseases in patients with hematologic malignancies
    Mary Mansour Riwes
    University of Florida, College of Medicine, Division of Hematology Oncology 1600 W Archer Road, Gainesville, FL 32610 0278, USA
    Expert Rev Hematol 5:661-9. 2012
    ..These new diagnostic methods facilitate an early diagnosis of invasive fungal disease and allow for utilization of a pre-emptive treatment approach, which may ultimately lead to improved treatment outcomes and reduced toxicity...
  54. ncbi request reprint Busulfan, cyclophosphamide, and etoposide as conditioning for autologous stem cell transplantation in multiple myeloma
    Christopher R Cogle
    University of Florida, Division of Hematology Oncology, Gainesville, Florida 32610, USA
    Am J Hematol 73:169-75. 2003
    ....
  55. doi request reprint African American adult apheresis donors respond to granulocyte-colony-stimulating factor with neutrophil and progenitor cell yields comparable to those of Caucasian and Hispanic donors
    Allison R Carilli
    Department of Medicine, University of Florida, Gainesville, Florida, USA
    Transfusion 52:166-72. 2012
    ..Persons of African descent have reduced neutrophil mobilization after steroid administration, and newborns have fewer nucleated and progenitor cells in their cord blood...
  56. ncbi request reprint Bone marrow transdifferentiation in brain after transplantation: a retrospective study
    Christopher R Cogle
    Program in Stem Cell Biology and Regenerative Medicine, University of Florida Shands Cancer Center, Gainesville, FL 32610, USA
    Lancet 363:1432-7. 2004
    ..We looked for evidence of clinically relevant marrow-derived restorative neurogenesis: long-term, multilineage, neural engraftment that is not the result of cell-fusion events...
  57. pmc Autologous umbilical cord blood transfusion in very young children with type 1 diabetes
    Michael J Haller
    Department of Pediatrics, The University of Florida, Gainesville, Florida, USA
    Diabetes Care 32:2041-6. 2009
    ..We conducted an open-label phase I study using autologous umbilical cord blood infusion to ameliorate type 1 diabetes...
  58. ncbi request reprint A prospective randomized trial of prophylactic platelet transfusion and bleeding incidence in hematopoietic stem cell transplant recipients: 10,000/L versus 20,000/microL trigger
    Marc S Zumberg
    University of Florida College of Medicine, Department of Medicine, Gainesville 32610, USA
    Biol Blood Marrow Transplant 8:569-76. 2002
    ..In conclusion, a platelet transfusion trigger of 10K was found to be safe; however, a decrease in platelet use was not achieved because of safety measures incorporated into our study design...
  59. ncbi request reprint The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of multiple myeloma: an evidence-based review
    Theresa Hahn
    Roswell Park Cancer Institute, Department of Medicine, Buffalo, New York 14263, USA
    Biol Blood Marrow Transplant 9:4-37. 2003
    ..The priority area of needed future research is maintenance therapy posttransplantation with nothing versus interferon alpha versus other agents such as corticosteroids or thalidomide or its derivatives...
  60. ncbi request reprint The changing face of invasive fungal infections in hematopoietic cell transplant recipients
    John R Wingard
    Department of Medicine, University of Florida Shands Cancer Center, Division of Hematology Oncology, Gainesville, Florida 32610 0277, USA
    Curr Opin Oncol 17:89-92. 2005
    ....
  61. ncbi request reprint Typhlitis with concurrent appendicitis in a patient with chronic lymphocytic leukemia
    Christopher R Cogle
    University of Florida Shands Cancer Center, Gainesville, FL 32610, USA
    Clin Adv Hematol Oncol 1:284-6; discussion 286. 2003
  62. ncbi request reprint Hematopoietic stem cell transplantation: an overview of infection risks and epidemiology
    John R Wingard
    Bone Marrow Transplant Program, Division of Hematology Oncology, University of Florida College of Medicine, PO Box 100278, 1600 SW Archer Road, Gainesville, FL 32610 0278, USA
    Hematol Oncol Clin North Am 25:101-16. 2011
    ..Over time, with strengthening immune reconstitution and control of graft-versus-host disease, the risk for infection dissipates...
  63. ncbi request reprint Antifungal chemoprophylaxis after blood and marrow transplantation
    John R Wingard
    Division of Hematology Oncology, University of Florida College of Medicine, Gainesville, FL 32610, USA
    Clin Infect Dis 34:1386-90. 2002
    ..Fluconazole prophylaxis is highly effective for the control of invasive yeast infections and associated with few breakthrough infections. The development of antimould prophylaxis in this patient population is a high priority...
  64. ncbi request reprint Factors associated with parameters of engraftment potential of umbilical cord blood
    Thomas J George
    University of Florida, College of Medicine, Gainesville, Florida, USA
    Transfusion 46:1803-12. 2006
    ..A total of 1033 UCB samples with neonatal and paternal characteristics that might influence hematopoietic content were examined...
  65. ncbi request reprint Assessing responses to treatment of opportunistic mycoses and salvage strategies
    Baldeep Wirk
    Bone Marrow Transplant Program, College of Medicine, University of Florida, 1600 SW Archer Road, PO Box 100277, Gainesville, FL, 32610, USA
    Curr Infect Dis Rep 13:492-503. 2011
    ....
  66. ncbi request reprint Preparing for the unthinkable: emergency preparedness for the hematopoietic cell transplant program
    John R Wingard
    University of Florida College of Medicine, Gainesville, FL 32610 0277, USA
    Biol Blood Marrow Transplant 12:1229-38. 2006
    ..This report provides the framework for a HCT-specific emergency preparedness plan that can be used by individual centers to develop customized guidelines on preparing for, responding to, and recovering from an emergency...