S J Wimalawansa

Summary

Affiliation: University of Texas Medical Branch
Country: USA

Publications

  1. ncbi request reprint Prevention of corticosteroid-induced bone loss with nitric oxide donor nitroglycerin in male rats
    S J Wimalawansa
    Department of Internal Medicine, University of Texas Medical Branch at Galveston 77555 1065, USA
    Bone 21:275-80. 1997
  2. ncbi request reprint Nitric oxide donor alleviates ovariectomy-induced bone loss
    S J Wimalawansa
    Department of Internal Medicine, University of Texas Medical Branch at Galveston, USA
    Bone 18:301-4. 1996
  3. ncbi request reprint Prevention of corticosteroid-induced bone loss with alendronate
    S J Wimalawansa
    Department of Internal Medicine, The University of Texas Medical Branch at Galveston, 77555 1065, USA
    Proc Soc Exp Biol Med 217:162-7. 1998
  4. ncbi request reprint Infusion of pregnant rats with calcitonin gene-related peptide (CGRP)(8-37), a CGRP receptor antagonist, increases blood pressure and fetal mortality and decreases fetal growth
    P R R Gangula
    Department of Obstetrics Gynecology, The University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 1062, USA
    Biol Reprod 67:624-9. 2002
  5. ncbi request reprint Pregnancy and steroid hormones enhance the systemic and regional hemodynamic effects of calcitonin gene-related peptide in rats
    P R Gangula
    Departments of Ob/Gyn and Internal Medicine, The University of Texas Medical Branch, Galveston, Texas 77555-1062, USA
    Biol Reprod 64:1776-83. 2001
  6. ncbi request reprint Mechanisms involved in calcitonin gene-related Peptide-induced relaxation in pregnant rat uterine artery
    P R R Gangula
    Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas 77555, USA
    Biol Reprod 69:1635-41. 2003
  7. ncbi request reprint Female sex steroid hormones and pregnancy regulate receptors for calcitonin gene-related peptide in rat mesenteric arteries, but not in aorta
    C Yallampalli
    Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas 77555 1062, USA
    Biol Reprod 70:1055-62. 2004
  8. ncbi request reprint Studies on the effects of the N-terminal domain antibodies of calcitonin receptor-like receptor and receptor activity-modifying protein 1 on calcitonin gene-related peptide-induced vasorelaxation in rat uterine artery
    M Chauhan
    Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas 77555 1062, USA
    Biol Reprod 70:1658-63. 2004
  9. ncbi request reprint Sex steroid hormones enhance hypotensive effects of calcitonin gene-related Peptide in aged female rats
    P R R Gangula
    Department of Obstetrics Gynecology, University of Texas Medical Branch, Galveston 77555 1062, USA
    Biol Reprod 67:1881-7. 2002
  10. ncbi request reprint NK1, NK2, NK3 and CGRP1 receptors identified in rat oral soft tissues, and in bone and dental hard tissue cells
    I Fristad
    Department of Odontology Endodontics, School of Dentistry, University of Bergen, Arstadveien 17, 5009, Bergen, Norway
    Cell Tissue Res 311:383-91. 2003

Collaborators

  • C Yallampalli
  • S C Supowit
  • L Zhang
  • P R R Gangula
  • P R Gangula
  • R D Bukoski
  • P Lanlua
  • M Chauhan
  • I Fristad
  • D J Dipette
  • H Zhao
  • C Thota
  • V Vandevska-Radunovic
  • I Hals Kvinnsland
  • K Fjeld
  • Y L Dong
  • K N Westlund
  • R F Gagel

Detail Information

Publications16

  1. ncbi request reprint Prevention of corticosteroid-induced bone loss with nitric oxide donor nitroglycerin in male rats
    S J Wimalawansa
    Department of Internal Medicine, University of Texas Medical Branch at Galveston 77555 1065, USA
    Bone 21:275-80. 1997
    ..Here, we demonstrate, for the first time, that supplementation with a NO donor compound can counteract prednisolone-induced bone loss...
  2. ncbi request reprint Nitric oxide donor alleviates ovariectomy-induced bone loss
    S J Wimalawansa
    Department of Internal Medicine, University of Texas Medical Branch at Galveston, USA
    Bone 18:301-4. 1996
    ..In summary, the results suggest that NO counteracts the bone loss associated with OVX...
  3. ncbi request reprint Prevention of corticosteroid-induced bone loss with alendronate
    S J Wimalawansa
    Department of Internal Medicine, The University of Texas Medical Branch at Galveston, 77555 1065, USA
    Proc Soc Exp Biol Med 217:162-7. 1998
    ..In summary, this study demonstrated that alendronate therapy is highly effective in counteracting the osteopenia of OVX and glucocorticoid therapy...
  4. ncbi request reprint Infusion of pregnant rats with calcitonin gene-related peptide (CGRP)(8-37), a CGRP receptor antagonist, increases blood pressure and fetal mortality and decreases fetal growth
    P R R Gangula
    Department of Obstetrics Gynecology, The University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 1062, USA
    Biol Reprod 67:624-9. 2002
    ..Therefore, we suggest that endogenous CGRP plays an important role in maintaining normal fetoplacental development, fetal survival, and vascular adaptations during pregnancy...
  5. ncbi request reprint Pregnancy and steroid hormones enhance the systemic and regional hemodynamic effects of calcitonin gene-related peptide in rats
    P R Gangula
    Departments of Ob/Gyn and Internal Medicine, The University of Texas Medical Branch, Galveston, Texas 77555-1062, USA
    Biol Reprod 64:1776-83. 2001
    ..Thus, CGRP-induced vasodilatory effects may play a role in mediating vascular adaptations that occur during pregnancy and that steroid hormones may modulate these CGRP effects...
  6. ncbi request reprint Mechanisms involved in calcitonin gene-related Peptide-induced relaxation in pregnant rat uterine artery
    P R R Gangula
    Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas 77555, USA
    Biol Reprod 69:1635-41. 2003
    ..These studies suggest that CGRP-induced increases in uterine artery relaxation may play a role in regulating blood flow to the uterus during pregnancy and, therefore, in fetal growth and survival...
  7. ncbi request reprint Female sex steroid hormones and pregnancy regulate receptors for calcitonin gene-related peptide in rat mesenteric arteries, but not in aorta
    C Yallampalli
    Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas 77555 1062, USA
    Biol Reprod 70:1055-62. 2004
    ....
  8. ncbi request reprint Studies on the effects of the N-terminal domain antibodies of calcitonin receptor-like receptor and receptor activity-modifying protein 1 on calcitonin gene-related peptide-induced vasorelaxation in rat uterine artery
    M Chauhan
    Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas 77555 1062, USA
    Biol Reprod 70:1658-63. 2004
    ..These studies suggest that CGRP effects in rat uterine artery are mediated through CGRP-A receptor and that Nt-domain of CRLR may play a predominant role in CGRP binding and thus in causing CGRP-induced uterine artery relaxation...
  9. ncbi request reprint Sex steroid hormones enhance hypotensive effects of calcitonin gene-related Peptide in aged female rats
    P R R Gangula
    Department of Obstetrics Gynecology, University of Texas Medical Branch, Galveston 77555 1062, USA
    Biol Reprod 67:1881-7. 2002
    ..These data suggest that female sex steroid hormones may modulate arterial blood pressure by regulating the CGRP effector system in female rats regardless of age...
  10. ncbi request reprint NK1, NK2, NK3 and CGRP1 receptors identified in rat oral soft tissues, and in bone and dental hard tissue cells
    I Fristad
    Department of Odontology Endodontics, School of Dentistry, University of Bergen, Arstadveien 17, 5009, Bergen, Norway
    Cell Tissue Res 311:383-91. 2003
    ....
  11. ncbi request reprint Effects of pregnancy and female sex steroid hormones on calcitonin gene-related peptide content of mesenteric artery in rats
    P Lanlua
    Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, Texas 77555, USA
    Biol Reprod 67:1430-4. 2002
    ..Because both CGRP levels in DRG and serum are reported to be elevated, the reduced CGRP content in the vasculature during pregnancy and proestrus implicate enhanced basal release of CGRP at the nerve terminal in these animals...
  12. ncbi request reprint Isolation, purification and characterization of beta-hCGRP from human spinal cord
    S J Wimalawansa
    Department of Medicine, Royal Postgraduate Medical School, London, UK
    Biochem Biophys Res Commun 167:993-1000. 1990
    ....
  13. ncbi request reprint Arthritic calcitonin/alpha calcitonin gene-related peptide knockout mice have reduced nociceptive hypersensitivity
    L Zhang
    Department of Anatomy and Neurosciences, The University of Texas Medical Branch at Galveston, 301 University Boulevard, Galveston, TX 77555 1069, USA
    Pain 89:265-73. 2001
    ..These results indicate that endogenous CGRP plays an important role in the plastic neurogenic changes occurring in response to peripheral inflammatory events including the development of nociceptive behaviors...
  14. ncbi request reprint Increased blood pressure in alpha-calcitonin gene-related peptide/calcitonin gene knockout mice
    P R Gangula
    Departments of Obstetrics and Gynecology, Internal Medicine, and Anatomy and Neurosciences, The University of Texas Medical Branch, Galveston, TX 77555 1062, USA
    Hypertension 35:470-5. 2000
    ....
  15. ncbi request reprint Antihypertensive effects of oral calcium supplementation may be mediated through the potent vasodilator CGRP
    S J Wimalawansa
    Department of Medicine (Endocrinology, Royal Post-graduate Medical School, London
    Am J Hypertens 6:996-1002. 1993
    ..05). Following cessation of calcium supplementation, plasma CGRP levels and the blood pressure both reverted back to the base-line values, suggesting a direct effect of supplemented calcium on these two parameters...
  16. ncbi request reprint Mesenteric arterial relaxation to calcitonin gene-related peptide is increased during pregnancy and by sex steroid hormones
    P R R Gangula
    Department of Obstetrics and Gynecology, The University of Texas Medical Branch, 301 University Boulevard, Galveston, Texas 77555, USA
    Biol Reprod 71:1739-45. 2004
    ..Therefore, we propose that CGRP-mediated vasodilation may be important to maintain vascular adaptations during pregnancy...