Nancy A Wilson

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. pmc Simian immunodeficiency virus-specific CD4+ T cells from successful vaccinees target the SIV Gag capsid
    Juan P Giraldo-Vela
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, WI 53711, USA
    Immunogenetics 62:701-7. 2010
  2. pmc Vaccine-induced cellular immune responses reduce plasma viral concentrations after repeated low-dose challenge with pathogenic simian immunodeficiency virus SIVmac239
    Nancy A Wilson
    Wisconsin National Primate Research Center, University of Wisconsin Madison, Madison, WI 53711, USA
    J Virol 80:5875-85. 2006
  3. pmc Vaccine-induced cellular responses control simian immunodeficiency virus replication after heterologous challenge
    Nancy A Wilson
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, Wisconsin 53711, USA
    J Virol 83:6508-21. 2009
  4. pmc Is an HIV vaccine possible?
    Nancy A Wilson
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Wisconsin 53711, USA
    Braz J Infect Dis 13:304-10. 2009
  5. pmc Comprehensive immunological evaluation reveals surprisingly few differences between elite controller and progressor Mamu-B*17-positive simian immunodeficiency virus-infected rhesus macaques
    Nicholas J Maness
    Wisconsin National Primate Research Center, University of Wisconsin Madison, Madison, Wisconsin 53711, USA
    J Virol 82:5245-54. 2008
  6. pmc Patterns of CD8+ immunodominance may influence the ability of Mamu-B*08-positive macaques to naturally control simian immunodeficiency virus SIVmac239 replication
    John T Loffredo
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, 555 Science Dr, Madison, WI 53711, USA
    J Virol 82:1723-38. 2008
  7. pmc The role of MHC class I allele Mamu-A*07 during SIV(mac)239 infection
    Jason S Reed
    Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, USA
    Immunogenetics 63:789-807. 2011
  8. pmc Robust, vaccine-induced CD8(+) T lymphocyte response against an out-of-frame epitope
    Nicholas J Maness
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, WI 53706, USA
    J Immunol 184:67-72. 2010
  9. pmc Gag- and Nef-specific CD4+ T cells recognize and inhibit SIV replication in infected macrophages early after infection
    Jonah B Sacha
    Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI 53715, USA
    Proc Natl Acad Sci U S A 106:9791-6. 2009
  10. pmc Effective simian immunodeficiency virus-specific CD8+ T cells lack an easily detectable, shared characteristic
    Lara Vojnov
    Department of Pathology, University of Wisconsin Madison, 555 Science Dr, Madison, WI 53711, USA
    J Virol 84:753-64. 2010

Collaborators

Detail Information

Publications50

  1. pmc Simian immunodeficiency virus-specific CD4+ T cells from successful vaccinees target the SIV Gag capsid
    Juan P Giraldo-Vela
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, WI 53711, USA
    Immunogenetics 62:701-7. 2010
    ..Analysis of SIV-specific CD4+ T-cell responses elicited by a successful vaccine may have important implications in the understanding of vaccine design...
  2. pmc Vaccine-induced cellular immune responses reduce plasma viral concentrations after repeated low-dose challenge with pathogenic simian immunodeficiency virus SIVmac239
    Nancy A Wilson
    Wisconsin National Primate Research Center, University of Wisconsin Madison, Madison, WI 53711, USA
    J Virol 80:5875-85. 2006
    ....
  3. pmc Vaccine-induced cellular responses control simian immunodeficiency virus replication after heterologous challenge
    Nancy A Wilson
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, Wisconsin 53711, USA
    J Virol 83:6508-21. 2009
    ....
  4. pmc Is an HIV vaccine possible?
    Nancy A Wilson
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Wisconsin 53711, USA
    Braz J Infect Dis 13:304-10. 2009
    ..This review will focus on recent developments in HIV vaccine development. We will deal largely with attempts to develop a T cell-based vaccine using the non-human primate SIV challenge model...
  5. pmc Comprehensive immunological evaluation reveals surprisingly few differences between elite controller and progressor Mamu-B*17-positive simian immunodeficiency virus-infected rhesus macaques
    Nicholas J Maness
    Wisconsin National Primate Research Center, University of Wisconsin Madison, Madison, Wisconsin 53711, USA
    J Virol 82:5245-54. 2008
    ..Most importantly, our data indicate that the important differences between Mamu-B*17-positive ECs and progressors are not readily discernible using standard assays to measure immune responses...
  6. pmc Patterns of CD8+ immunodominance may influence the ability of Mamu-B*08-positive macaques to naturally control simian immunodeficiency virus SIVmac239 replication
    John T Loffredo
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, 555 Science Dr, Madison, WI 53711, USA
    J Virol 82:1723-38. 2008
    ..Natural containment of AIDS virus replication in Mamu-B*08-positive macaques may, therefore, be related to a combination of immunodominance and viral escape from CD8(+) T-cell responses...
  7. pmc The role of MHC class I allele Mamu-A*07 during SIV(mac)239 infection
    Jason S Reed
    Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, USA
    Immunogenetics 63:789-807. 2011
    ..Thus, it appears that Mamu-A1*007:01 presents SIV-derived peptides to antigen-specific CD8(+) T cells and is part of the immune response to SIV(mac)239...
  8. pmc Robust, vaccine-induced CD8(+) T lymphocyte response against an out-of-frame epitope
    Nicholas J Maness
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, WI 53706, USA
    J Immunol 184:67-72. 2010
    ..Our data demonstrate both that the pathway from vaccination to immune response is not well understood and that products of alternate reading frames may be rich and untapped sources of T cell epitopes...
  9. pmc Gag- and Nef-specific CD4+ T cells recognize and inhibit SIV replication in infected macrophages early after infection
    Jonah B Sacha
    Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI 53715, USA
    Proc Natl Acad Sci U S A 106:9791-6. 2009
    ..These results suggest that retrovirus-specific CD4(+) T cells may contribute directly to elite control by inhibiting viral replication in macrophages...
  10. pmc Effective simian immunodeficiency virus-specific CD8+ T cells lack an easily detectable, shared characteristic
    Lara Vojnov
    Department of Pathology, University of Wisconsin Madison, 555 Science Dr, Madison, WI 53711, USA
    J Virol 84:753-64. 2010
    ..Our results suggest that a single definitive correlate of immune control may not exist; rather, a successful CD8(+) T-cell response may be comprised of several factors...
  11. pmc Infection with "escaped" virus variants impairs control of simian immunodeficiency virus SIVmac239 replication in Mamu-B*08-positive macaques
    Laura E Valentine
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    J Virol 83:11514-27. 2009
    ..04). Our results suggest that these epitope-specific CD8+ T-cell responses may play a role in establishing the control of viral replication in Mamu-B*08+ macaques...
  12. pmc The antiviral efficacy of simian immunodeficiency virus-specific CD8+ T cells is unrelated to epitope specificity and is abrogated by viral escape
    John T Loffredo
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, 555 Science Drive, Madison, WI 53711, USA
    J Virol 81:2624-34. 2007
    ..Understanding antiviral efficacy and epitope variability, therefore, will be important in selecting candidate epitopes for an HIV vaccine...
  13. pmc Pol-specific CD8+ T cells recognize simian immunodeficiency virus-infected cells prior to Nef-mediated major histocompatibility complex class I downregulation
    Jonah B Sacha
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, 555 Science Drive, Madison, WI 53711, USA
    J Virol 81:11703-12. 2007
    ..Finally, Pol-specific CD8+ T cells eliminated infected cells as early as 6 h postinfection, well before MHC-I downregulation, suggesting a previously underappreciated antiviral role for Pol-specific CD8+ T cells...
  14. pmc AIDS virus specific CD8+ T lymphocytes against an immunodominant cryptic epitope select for viral escape
    Nicholas J Maness
    Wisconsin National Primate Research Center, University of Wisconsin Madison, Madison, WI 53711, USA
    J Exp Med 204:2505-12. 2007
    ..The discovery of an immunodominant CD8-TL response in elite controller macaques against a cryptic epitope suggests that the AIDS virus-specific cellular immune response is likely far more complex than is generally assumed...
  15. ncbi request reprint Gag-specific CD8+ T lymphocytes recognize infected cells before AIDS-virus integration and viral protein expression
    Jonah B Sacha
    Wisconsin National Primate Research Center, University of Wisconsin Madison, Madison, WI 53711, USA
    J Immunol 178:2746-54. 2007
    ..0017) in SIV-infected rhesus macaques. These results suggest that HIV vaccines should focus CD8(+) T cell responses on Gag...
  16. pmc Acute phase CD8+ T lymphocytes against alternate reading frame epitopes select for rapid viral escape during SIV infection
    Andrew D Walsh
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 8:e61383. 2013
    ..Our data show that high frequency CTL target cryptic epitopes and exert selective pressure on SIV during the acute phase, underscoring the importance of these unique immune responses...
  17. pmc Vaccine-induced CD8+ T cells control AIDS virus replication
    Philip A Mudd
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, Wisconsin 53711, USA
    Nature 491:129-33. 2012
    ..Our findings indicate that narrowly targeted vaccine-induced virus-specific CD8(+) T-cell responses can control replication of the AIDS virus...
  18. pmc CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation
    John T Loffredo
    Wisconsin National Primate Research Center WNPRC, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 2:e1152. 2007
    ..SIV replication was rapidly controlled with the reappearance of CD8+ cells, implicating that these cells actively suppress viral replication in ECs...
  19. pmc CD8+ T cell recognition of cryptic epitopes is a ubiquitous feature of AIDS virus infection
    Nicholas J Maness
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, WI 53711, USA
    J Virol 84:11569-74. 2010
    ..The epitopes were targeted by high-frequency responses as early as 2 weeks postinfection and in the chronic phase. Hence, previously overlooked ARF-encoded epitopes could be important components of AIDS vaccines...
  20. pmc Novel translation products from simian immunodeficiency virus SIVmac239 Env-encoding mRNA contain both Rev and cryptic T-cell epitopes
    Nicholas J Maness
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, 555 Science Drive, Madison, WI 53711, USA
    J Virol 83:10280-5. 2009
    ..Our data suggest that the translation of viral alternate reading frames may be an important source of T-cell epitopes, including epitopes normally derived from functional proteins...
  21. pmc High viremia is associated with high levels of in vivo major histocompatibility complex class I Downregulation in rhesus macaques infected with simian immunodeficiency virus SIVmac239
    Thomas C Friedrich
    Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, Wisconsin 537061, USA
    J Virol 84:5443-7. 2010
    ..Our results suggest that a high level of MHC-I downregulation is a hallmark of fast disease progression in SIV infection...
  22. pmc The majority of freshly sorted simian immunodeficiency virus (SIV)-specific CD8(+) T cells cannot suppress viral replication in SIV-infected macrophages
    Lara Vojnov
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, Wisconsin, USA
    J Virol 86:4682-7. 2012
    ....
  23. pmc Escape from CD8(+) T cell responses in Mamu-B*00801(+) macaques differentiates progressors from elite controllers
    Philip A Mudd
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, WI 53711, USA
    J Immunol 188:3364-70. 2012
    ..By contrast, virus in elite controller macaques showed little evidence of variation in epitopes recognized by immunodominant CD8(+) T lymphocytes, implying that these cells play a role in viral control...
  24. pmc Macaques vaccinated with live-attenuated SIV control replication of heterologous virus
    Matthew R Reynolds
    AIDS Vaccine Research Laboratory, Wisconsin National Primate Research Center, University of Wisconsin Madison, Madison, WI 53715, USA
    J Exp Med 205:2537-50. 2008
    ....
  25. pmc GagCM9-specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivo
    Lara Vojnov
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 6:e23515. 2011
    ..It is possible that these seven animals failed to control viral replication because of the narrow TCR repertoire expressed by the GagCM9-specific CD8(+) T cell population elicited by vaccination and infection...
  26. pmc Two MHC class I molecules associated with elite control of immunodeficiency virus replication, Mamu-B*08 and HLA-B*2705, bind peptides with sequence similarity
    John T Loffredo
    Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI 53706, USA
    J Immunol 182:7763-75. 2009
    ....
  27. pmc A trivalent recombinant Ad5 gag/pol/nef vaccine fails to protect rhesus macaques from infection or control virus replication after a limiting-dose heterologous SIV challenge
    Matthew R Reynolds
    AIDS Vaccine Research Laboratory, 555 Science Drive, Madison, WI 53711, USA
    Vaccine 30:4465-75. 2012
    ..Our results are consistent with those observed in the Step trial and indicate that SIV immunization and challenge studies in macaque models of HIV infection can be informative in assessing pre-clinical HIV vaccines...
  28. doi request reprint Dengue virus-specific CD4+ and CD8+ T lymphocytes target NS1, NS3 and NS5 in infected Indian rhesus macaques
    Katherine M Mladinich
    Microbiology Doctoral Training Program, University of Wisconsin Madison, 1326 Microbial Sciences, 1550 Linden Drive, Madison, WI 53706, USA
    Immunogenetics 64:111-21. 2012
    ....
  29. pmc The live-attenuated yellow fever vaccine 17D induces broad and potent T cell responses against several viral proteins in Indian rhesus macaques--implications for recombinant vaccine design
    Philip A Mudd
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, 555 Science Dr, Madison, WI 53711, USA
    Immunogenetics 62:593-600. 2010
    ..The data also suggest potential immunogenic regions of YF17D that could serve as the focus of recombinant T cell vaccine development...
  30. pmc Macaques vaccinated with simian immunodeficiency virus SIVmac239Delta nef delay acquisition and control replication after repeated low-dose heterologous SIV challenge
    Matthew R Reynolds
    AIDS Vaccine Research Laboratory, 555 Science Dr, Madison, WI 53711, USA
    J Virol 84:9190-9. 2010
    ..Overall, our results suggest that a well-designed HIV vaccine might both reduce the rate of acquisition and control viral replication...
  31. pmc CD8+ T cell escape mutations in simian immunodeficiency virus SIVmac239 cause fitness defects in vivo, and many revert after transmission
    Philip A Mudd
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, 555 Science Dr, Madison, WI 53711, USA
    J Virol 85:12804-10. 2011
    ..Two of the three viruses demonstrated reduced fitness in vivo, and 27% of the introduced mutations reverted. These findings suggest that T cell epitope diversity may not be such a daunting problem for the development of an HIV vaccine...
  32. pmc Differential antigen presentation kinetics of CD8+ T-cell epitopes derived from the same viral protein
    Jonah B Sacha
    Wisconsin National Primate Research Center WNPRC, Madison, WI 53711, USA
    J Virol 82:9293-8. 2008
    ..These results illustrate that significant differences in presentation kinetics can exist among CD8+ T-cell epitopes derived from the same viral protein...
  33. pmc Subdominant CD8+ T-cell responses are involved in durable control of AIDS virus replication
    Thomas C Friedrich
    Wisconsin National Primate Research Center, 1220 Capitol Court, Madison, WI 53715 1299, USA
    J Virol 81:3465-76. 2007
    ..It is likely that subdominant CD8+ T-cell populations play a key role in maintaining this control...
  34. pmc Macaque long-term nonprogressors resist superinfection with multiple CD8+ T cell escape variants of simian immunodeficiency virus
    Jason T Weinfurter
    Department of Pathobiological Sciences, University of Wisconsin School of Veterinary Medicine, Madison, Wisconsin 53706, USA
    J Virol 85:530-41. 2011
    ..Our results suggest that escape mutations in epitopes bound by "protective" MHC-I molecules may not be sufficient to establish superinfection in LTNPs...
  35. pmc Simian immunodeficiency virus-specific CD8+ T cells recognize Vpr- and Rev-derived epitopes early after infection
    Jonah B Sacha
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, 555 Science Drive, Madison, WI 53711, USA
    J Virol 84:10907-12. 2010
    ..These studies show for the first time that Vpr- and Rev-specific CD8(+) T cells recognize and kill simian immunodeficiency virus (SIV)-infected CD4(+) T cells early after SIV infection...
  36. pmc Recombinant yellow fever vaccine virus 17D expressing simian immunodeficiency virus SIVmac239 gag induces SIV-specific CD8+ T-cell responses in rhesus macaques
    Myrna C Bonaldo
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, 555 Science Dr, Madison, WI 53711, USA
    J Virol 84:3699-706. 2010
    ..These recombinant YF17D-induced SIV-specific CD8(+) T cells secreted several cytokines, were largely effector memory T cells, and suppressed viral replication in CD4(+) T cells...
  37. pmc Pyrosequencing reveals restricted patterns of CD8+ T cell escape-associated compensatory mutations in simian immunodeficiency virus
    Benjamin J Burwitz
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, Madison, Wisconsin 537061, USA
    J Virol 85:13088-96. 2011
    ..This is the first detailed report of the ontogeny of compensatory mutations that allow CD8+ T cell epitope escape in infected individuals...
  38. pmc Whole-genome characterization of human and simian immunodeficiency virus intrahost diversity by ultradeep pyrosequencing
    Benjamin N Bimber
    University of Wisconsin Madison, Madison, WI 53711, USA
    J Virol 84:12087-92. 2010
    ..While this work applies pyrosequencing to immunodeficiency viruses, this approach could be applied to virtually any viral pathogen...
  39. pmc The major histocompatibility complex class II alleles Mamu-DRB1*1003 and -DRB1*0306 are enriched in a cohort of simian immunodeficiency virus-infected rhesus macaque elite controllers
    Juan P Giraldo-Vela
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, 555 Science Dr, Madison, WI 53711, USA
    J Virol 82:859-70. 2008
    ..0001). The study of MHC-II alleles in macaques that control viral replication could improve our understanding of the role of CD4(+) T cells in suppressing HIV/SIV replication and further our understanding of HIV vaccine design...
  40. pmc Recognition of escape variants in ELISPOT does not always predict CD8+ T-cell recognition of simian immunodeficiency virus-infected cells expressing the same variant sequences
    Laura E Valentine
    Wisconsin National Primate Research Center, Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, Wisconsin, USA
    J Virol 82:575-81. 2008
    ..Our results indicate that "cross-reactive" CD8(+) T-cell responses identified in ELISPOT and ICS assays using a single high concentration of variant peptide often fail to predict the recognition of cells infected with variant viruses...
  41. pmc Chinese origin rhesus macaque major histocompatibility complex class I molecules promiscuously present epitopes from SIV associated with molecules of Indian origin; implications for immunodominance and viral escape
    Nicholas James Maness
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, WI 53711, USA
    Immunogenetics 63:587-97. 2011
    ....
  42. pmc T-cell correlates of vaccine efficacy after a heterologous simian immunodeficiency virus challenge
    Mauricio A Martins
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, 555 Science Dr, Madison, WI 53711, USA
    J Virol 84:4352-65. 2010
    ..Furthermore, the present study demonstrates that certain viral proteins may be more effective than others as vaccine immunogens...
  43. pmc DNA/Ad5 vaccination with SIV epitopes induced epitope-specific CD4⁺ T cells, but few subdominant epitope-specific CD8⁺ T cells
    Lara Vojnov
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, 555 Science Drive, Madison, WI 53711, USA
    Vaccine 29:7483-90. 2011
    ..Broadening the CD8(+) T cell response against subdominant MHC class I epitopes was, therefore, more difficult than we initially anticipated...
  44. pmc Not all cytokine-producing CD8+ T cells suppress simian immunodeficiency virus replication
    Chungwon Chung
    Wisconsin National Primate Research Center, University of Wisconsin Madison, Madison, Wisconsin 53715 1299, USA
    J Virol 81:1517-23. 2007
    ..Interestingly, in vitro suppression efficacy was not always associated with the ability to produce gamma interferon, tumor necrosis factor alpha, or interleukin-2...
  45. pmc Reduction of CD4+ T cells in vivo does not affect virus load in macaque elite controllers
    Philip A Mudd
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, 555 Science Dr, Madison, WI 53711, USA
    J Virol 85:7454-9. 2011
    ..Viral loads remained stable throughout the experiment, suggesting that SIV-specific CD4(+) T cell responses may not play a direct role in controlling chronic viral replication in these elite controllers...
  46. pmc Tat(28-35)SL8-specific CD8+ T lymphocytes are more effective than Gag(181-189)CM9-specific CD8+ T lymphocytes at suppressing simian immunodeficiency virus replication in a functional in vitro assay
    John T Loffredo
    Wisconsin National Primate Research Center, University of Wisconsin Madison, Madison, WI 53715, USA
    J Virol 79:14986-91. 2005
    ..Such differences in antigen-specific CD8+-T-lymphocyte efficacy may be important for selecting CD8+ T lymphocyte epitopes for inclusion in future HIV vaccines...
  47. pmc Mamu-B*08-positive macaques control simian immunodeficiency virus replication
    John T Loffredo
    Wisconsin National Primate Research Center, University of Wisconsin Madison, 555 Science Drive, Madison, WI 53711, USA
    J Virol 81:8827-32. 2007
    ..002). Mamu-B*08-positive macaques may, therefore, provide a good model to understand the correlates of MHC class I allele-associated immune protection and viral containment in human elite controllers...
  48. pmc The TRIM5{alpha} genotype of rhesus macaques affects acquisition of simian immunodeficiency virus SIVsmE660 infection after repeated limiting-dose intrarectal challenge
    Matthew R Reynolds
    AIDS Vaccine Research Laboratory, 555 Science Dr, Madison, WI 53711, USA
    J Virol 85:9637-40. 2011
    ..Our results indicate that the TRIM5 alleles can be a barrier to productive infection and that this should be taken into account when designing acquisition studies using SIVsmE660 or related viruses...
  49. ncbi request reprint The high frequency Indian rhesus macaque MHC class I molecule, Mamu-B*01, does not appear to be involved in CD8+ T lymphocyte responses to SIVmac239
    John T Loffredo
    Wisconsin National Primate Research Center WNPRC, University of Wisconsin, Madison, WI 53715, USA
    J Immunol 175:5986-97. 2005
    ..Our results suggest that the high frequency MHC class I molecule, Mamu-B*01, is not involved in SIV-specific CD8+ T lymphocyte responses...
  50. ncbi request reprint Identification of seventeen new simian immunodeficiency virus-derived CD8+ T cell epitopes restricted by the high frequency molecule, Mamu-A*02, and potential escape from CTL recognition
    John T Loffredo
    National Primate Research Center, University of Wisconsin WPRC, Madison 53715, USA
    J Immunol 173:5064-76. 2004
    ..This work enhances the use of the SIV-infected macaque model for HIV and increases our understanding of the breadth of CD8+ T cell responses in SIV infection...