CAROLINE WILMOT

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. pmc MauG: a di-heme enzyme required for methylamine dehydrogenase maturation
    Carrie M Wilmot
    Department of Biochemistry, Molecular Biology and Biophysics, Minneapolis, Minnesota 55455, USA
    Dalton Trans 42:3127-35. 2013
  2. ncbi request reprint Polysaccharide monoxygenases: giving a boost to biofuel production
    Carrie M Wilmot
    Department of Biochemistry, Molecular Biology and Biophysics, 6 155 Jackson Hall, 321 Church St SE, University of Minnesota, Minneapolis, MN 55455, USA
    Structure 20:938-40. 2012
  3. ncbi request reprint Oxygen activation in a copper-containing amine oxidase
    C M Wilmot
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 6 155 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455, USA
    Biochem Soc Trans 31:493-6. 2003
  4. ncbi request reprint Medical implications from the crystal structure of a copper-containing amine oxidase complexed with the antidepressant drug tranylcypromine
    Carrie M Wilmot
    Astbury Centre for Structural Molecular Biology, School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK
    FEBS Lett 576:301-5. 2004
  5. pmc Biochemistry. An ancient and intimate partnership
    Carrie M Wilmot
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA
    Science 316:379-80. 2007
  6. pmc Uncovering novel biochemistry in the mechanism of tryptophan tryptophylquinone cofactor biosynthesis
    Carrie M Wilmot
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 321 Church Street SE, Minneapolis, MN 55455, USA
    Curr Opin Chem Biol 13:469-74. 2009

Research Grants

Detail Information

Publications6

  1. pmc MauG: a di-heme enzyme required for methylamine dehydrogenase maturation
    Carrie M Wilmot
    Department of Biochemistry, Molecular Biology and Biophysics, Minneapolis, Minnesota 55455, USA
    Dalton Trans 42:3127-35. 2013
    ..Bis-Fe(IV) MauG acts as a potent 2-electron oxidant. Catalysis is long-range and requires a hole hopping electron transfer mechanism. This review highlights the current knowledge and focus of research into this fascinating system...
  2. ncbi request reprint Polysaccharide monoxygenases: giving a boost to biofuel production
    Carrie M Wilmot
    Department of Biochemistry, Molecular Biology and Biophysics, 6 155 Jackson Hall, 321 Church St SE, University of Minnesota, Minneapolis, MN 55455, USA
    Structure 20:938-40. 2012
    ..Additionally, the organization of aromatic amino acids and glycosylation on the carbohydrate binding surfaces suggests that regiospecificity and cellulose orientation can be predicted...
  3. ncbi request reprint Oxygen activation in a copper-containing amine oxidase
    C M Wilmot
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 6 155 Jackson Hall, 321 Church Street SE, Minneapolis, MN 55455, USA
    Biochem Soc Trans 31:493-6. 2003
    ..This structure has revealed many details regarding oxygen activation in ECAO, including the site of dioxygen binding, and the proton-transfer pathways involved in H(2)O(2) formation...
  4. ncbi request reprint Medical implications from the crystal structure of a copper-containing amine oxidase complexed with the antidepressant drug tranylcypromine
    Carrie M Wilmot
    Astbury Centre for Structural Molecular Biology, School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK
    FEBS Lett 576:301-5. 2004
    ..The inhibition of human copper amine oxidases could be a source of side-effects in its use as an antidepressant to inhibit the flavin-containing monoamine oxidases in the brain...
  5. pmc Biochemistry. An ancient and intimate partnership
    Carrie M Wilmot
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA
    Science 316:379-80. 2007
  6. pmc Uncovering novel biochemistry in the mechanism of tryptophan tryptophylquinone cofactor biosynthesis
    Carrie M Wilmot
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 321 Church Street SE, Minneapolis, MN 55455, USA
    Curr Opin Chem Biol 13:469-74. 2009
    ..This high-valent diheme species is an alternative to Compound I, an Fe(IV)=O heme with a porphyrin or amino acid cation radical, which is typically the reactive intermediate of heme-dependent oxygenases and peroxidases...

Research Grants11

  1. Biosynthesis of Amino Acid Derived Quinone Cofactors
    CAROLINE MARY WILMOT; Fiscal Year: 2010
    ....
  2. Catalysis and biogenesis in methylamine dehydrogenase
    CAROLINE WILMOT; Fiscal Year: 2002
    ..abstract_text> ..
  3. Biosynthesis of Amino Acid Derived Quinone Cofactors
    CAROLINE WILMOT; Fiscal Year: 2009
    ....
  4. Catalysis and biogenesis in methylamine dehydrogenase
    CAROLINE WILMOT; Fiscal Year: 2006
    ..abstract_text> ..
  5. Catalysis and biogenesis in methylamine dehydrogenase
    CAROLINE WILMOT; Fiscal Year: 2005
    ..abstract_text> ..
  6. Catalysis and biogenesis in methylamine dehydrogenase
    CAROLINE WILMOT; Fiscal Year: 2004
    ..abstract_text> ..
  7. Catalysis and biogenesis in methylamine dehydrogenase
    CAROLINE WILMOT; Fiscal Year: 2004
    ..abstract_text> ..
  8. Upgrade of Macromolecular X-ray Diffraction Facilities
    CAROLINE WILMOT; Fiscal Year: 2004
    ..The majority of the funding that supports these research areas is provided through grants from the National Institutes of Health. ..
  9. Catalysis and biogenesis in methylamine dehydrogenase
    CAROLINE WILMOT; Fiscal Year: 2003
    ..abstract_text> ..
  10. Biosynthesis of Amino Acid Derived Quinone Cofactors
    CAROLINE WILMOT; Fiscal Year: 2009
    ....