James H Willig

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi request reprint Nucleoside reverse-transcriptase inhibitor dosing errors in an outpatient HIV clinic in the electronic medical record era
    James H Willig
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, USA
    Clin Infect Dis 45:658-61. 2007
  2. pmc Effect of persistency of first-line HIV antiretroviral therapy on clinical outcomes
    James H Willig
    University of Alabama at Birmingham UAB, Birmingham, AL, USA
    AIDS Res Hum Retroviruses 29:698-703. 2013
  3. pmc Maraviroc observational study: the impact of expanded resistance testing and clinical considerations for antiretroviral regimen selection in treatment-experienced patients
    James H Willig
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    AIDS Res Hum Retroviruses 29:105-11. 2013
  4. pmc Darunavir outcomes study: comparative effectiveness of virologic suppression, regimen durability, and discontinuation reasons for three-class experienced patients at 48 weeks
    James H Willig
    Division of Infectious Diseases, Department of Internal Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
    AIDS Res Hum Retroviruses 26:1279-85. 2010
  5. ncbi request reprint Clinical inertia in the management of low-density lipoprotein abnormalities in an HIV clinic
    James H Willig
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, USA
    Clin Infect Dis 46:1315-8. 2008
  6. pmc Increased regimen durability in the era of once-daily fixed-dose combination antiretroviral therapy
    James H Willig
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
    AIDS 22:1951-60. 2008
  7. ncbi request reprint Durability of initial antiretroviral therapy in a resource-constrained setting and the potential need for zidovudine weight-based dosing
    James H Willig
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, AL, USA
    J Acquir Immune Defic Syndr 53:215-21. 2010
  8. pmc The therapeutic implications of timely linkage and early retention in HIV care
    Kimberly B Ulett
    University of Alabama School of Medicine, Birmingham, Alabama, USA
    AIDS Patient Care STDS 23:41-9. 2009
  9. ncbi request reprint Routine depression screening in an HIV clinic cohort identifies patients with complex psychiatric co-morbidities who show significant response to treatment
    Joseph E Schumacher
    Division of Preventive Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
    AIDS Behav 17:2781-91. 2013
  10. pmc Antiretroviral prescribing patterns in treatment-naïve patients in the United States
    James A McKinnell
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
    AIDS Patient Care STDS 24:79-85. 2010

Collaborators

Detail Information

Publications43

  1. ncbi request reprint Nucleoside reverse-transcriptase inhibitor dosing errors in an outpatient HIV clinic in the electronic medical record era
    James H Willig
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, USA
    Clin Infect Dis 45:658-61. 2007
    ..Understanding the factors related to nucleoside reverse-transcriptase inhibitor dosing errors is an important step in the building of preventive tools...
  2. pmc Effect of persistency of first-line HIV antiretroviral therapy on clinical outcomes
    James H Willig
    University of Alabama at Birmingham UAB, Birmingham, AL, USA
    AIDS Res Hum Retroviruses 29:698-703. 2013
    ..Given these findings, the relationship between persistency and clinical outcomes merits further study...
  3. pmc Maraviroc observational study: the impact of expanded resistance testing and clinical considerations for antiretroviral regimen selection in treatment-experienced patients
    James H Willig
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    AIDS Res Hum Retroviruses 29:105-11. 2013
    ....
  4. pmc Darunavir outcomes study: comparative effectiveness of virologic suppression, regimen durability, and discontinuation reasons for three-class experienced patients at 48 weeks
    James H Willig
    Division of Infectious Diseases, Department of Internal Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
    AIDS Res Hum Retroviruses 26:1279-85. 2010
    ..New agents have transformed the treatment landscape for ARV-experienced patients, with effectiveness in routine clinical care mirroring efficacy in clinical trials...
  5. ncbi request reprint Clinical inertia in the management of low-density lipoprotein abnormalities in an HIV clinic
    James H Willig
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, USA
    Clin Infect Dis 46:1315-8. 2008
    ..Clinical inertia was observed in 44% of cases. Patients with higher baseline LDL levels were less likely to experience inertia, whereas women and those in the highest coronary heart disease risk category were more likely to be affected...
  6. pmc Increased regimen durability in the era of once-daily fixed-dose combination antiretroviral therapy
    James H Willig
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
    AIDS 22:1951-60. 2008
    ..Modern regimens are thought to possess greater tolerability and convenience. We hypothesized this would translate into greater durability...
  7. ncbi request reprint Durability of initial antiretroviral therapy in a resource-constrained setting and the potential need for zidovudine weight-based dosing
    James H Willig
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, AL, USA
    J Acquir Immune Defic Syndr 53:215-21. 2010
    ..Whereas access to antiretroviral therapy (ART) for HIV-infected individuals in the developing world is increasing, data on factors impacting initial regimen durability are lacking...
  8. pmc The therapeutic implications of timely linkage and early retention in HIV care
    Kimberly B Ulett
    University of Alabama School of Medicine, Birmingham, Alabama, USA
    AIDS Patient Care STDS 23:41-9. 2009
    ..Missed clinic visits represent an important obstacle to the timely initiation of antiretroviral therapy. These data inform development of interventions to improve linkage and retention in HIV care, an emerging area of growing importance...
  9. ncbi request reprint Routine depression screening in an HIV clinic cohort identifies patients with complex psychiatric co-morbidities who show significant response to treatment
    Joseph E Schumacher
    Division of Preventive Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
    AIDS Behav 17:2781-91. 2013
    ..HIV clinics can routinely screen and treat depressive symptoms, but should consider accurate psychiatric diagnosis as well as co-occurring mental disorders...
  10. pmc Antiretroviral prescribing patterns in treatment-naïve patients in the United States
    James A McKinnell
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
    AIDS Patient Care STDS 24:79-85. 2010
    ..In contrast, regimen sequencing beyond the first regimen remained complex. These shifts in ART prescribing patterns may have implications for collaborative HIV care...
  11. pmc Missed visits and mortality among patients establishing initial outpatient HIV treatment
    Michael J Mugavero
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, 908 20th St South, Birmingham, AL 35294 2050, USA
    Clin Infect Dis 48:248-56. 2009
    ....
  12. pmc Comparative efficacy versus effectiveness of initial antiretroviral therapy in clinical trials versus routine care
    Justin S Routman
    Divisions of Infectious Diseases, Department of Medicine, University of Alabama School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 2050, USA
    Clin Infect Dis 50:574-84. 2010
    ..Although well-chronicled in many conditions, the efficacy versus effectiveness of antiretroviral therapy (ART) remains understudied...
  13. pmc Short-term discontinuation of HAART regimens more common in vulnerable patient populations
    Lindsay S Robison
    University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    AIDS Res Hum Retroviruses 24:1347-55. 2008
    ..S. HIV/AIDS epidemic. More vigilant monitoring of patient populations at higher risk of toxicity and virologic failure may allow for improved HAART regimen durability...
  14. pmc HIV infection and obesity: where did all the wasting go?
    Tyler Tate
    Department of Medicine, University of Alabama School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Antivir Ther 17:1281-9. 2012
    ..As chronic diseases rates have increased in HIV+ populations, modifiable risk factors such as obesity have increased in importance. Our objective was to evaluate factors associated with weight change among patients receiving ART...
  15. pmc Temporal trends in presentation for outpatient HIV medical care 2000-2010: implications for short-term mortality
    Paula S Seal
    Department of Internal Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, CCB 142, 908 20th Street So, Birmingham, AL 35294 2050, USA
    J Gen Intern Med 26:745-50. 2011
    ..Many newly diagnosed patients present to outpatient care with advanced HIV infection. More timely HIV diagnosis and initiation of care has the potential to improve individual health outcomes and has public health implications...
  16. ncbi request reprint Early virologic suppression with three-class experienced patients: 24-week effectiveness in the darunavir outcomes study
    James A McKinnell
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA
    AIDS 23:1539-46. 2009
    ....
  17. pmc Pain, mood, and substance abuse in HIV: implications for clinic visit utilization, antiretroviral therapy adherence, and virologic failure
    Jessica S Merlin
    Division of Infectious Diseases, Department of Medicine, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA
    J Acquir Immune Defic Syndr 61:164-70. 2012
    ..Our objective was to investigate the relationship between pain, alone and in the context of mood disorders and substance abuse, on clinic utilization, antiretroviral therapy adherence, and virologic suppression...
  18. pmc Patient reported outcomes in routine care: advancing data capture for HIV cohort research
    Michael S Kozak
    Department of Internal Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, AL 35294 2050, USA
    Clin Infect Dis 54:141-7. 2012
    ..Comparisons between data from PROs and Electronic Health Records (EHR) are lacking. We compare EHR and PRO for capture of depression and substance abuse and their relationship to adherence to antiretroviral therapy (ART)...
  19. pmc Multimorbidity patterns in HIV-infected patients: the role of obesity in chronic disease clustering
    David J Kim
    University of Alabama School of Medicine, Birmingham, AL 35294 2050, USA
    J Acquir Immune Defic Syndr 61:600-5. 2012
    ..Increases in multimorbidity and obesity have been noted in HIV-infected populations in the current treatment era. Patterns of multimorbid disease clustering and the impact of obesity on multimorbidity are understudied in this population...
  20. pmc Early retention in HIV care and viral load suppression: implications for a test and treat approach to HIV prevention
    Michael J Mugavero
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, USA
    J Acquir Immune Defic Syndr 59:86-93. 2012
    ..We evaluated factors associated with expeditious VL suppression and cumulative VL burden among patients establishing outpatient HIV care...
  21. pmc Racial disparities in HIV virologic failure: do missed visits matter?
    Michael J Mugavero
    Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA
    J Acquir Immune Defic Syndr 50:100-8. 2009
    ..Racial/ethnic health care disparities are well described in people living with HIV/AIDS, although the processes underlying observed disparities are not well elucidated...
  22. doi request reprint Uncompensated medical provider costs associated with prior authorization for prescription medications in an HIV clinic
    James L Raper
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, AL 35294 2050, USA
    Clin Infect Dis 51:718-24. 2010
    ..60 per PA. Although evidence supports that PA reduces third-party expenditures, it significantly delays medication accessibility for patients and imposes high costs that negatively impact operating margins for health care providers...
  23. pmc The role of toxicity-related regimen changes in the development of antiretroviral resistance
    Christa R Nevin
    Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, USA
    AIDS Res Hum Retroviruses 27:957-63. 2011
    ..Understanding the role of ARV drug selection and other factors associated with the emergence of ARV resistance will help inform interventions to improve patient care and ensure long-term treatment success...
  24. pmc Underutilization of the AIDS Drug Assistance Program: associated factors and policy implications
    Noah C Godwin
    University of Alabama School of Medicine, 908 20th St South, Birmingham, AL 35294, USA
    Health Serv Res 46:982-95. 2011
    ..The AIDS Drug Assistance Program (ADAP) provides antiretroviral medications to low-income individuals with HIV infection...
  25. doi request reprint Mortality after cancer diagnosis in HIV-infected individuals treated with antiretroviral therapy
    Chad J Achenbach
    Division of Infectious Diseases, Center for Global Health, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    AIDS 25:691-700. 2011
    ..To evaluate survival and predictors of mortality after cancer diagnosis among HIV-infected persons receiving combination antiretroviral therapy (cART)...
  26. doi request reprint Clinical outcome of HIV-infected antiretroviral-naive patients with discordant immunologic and virologic responses to highly active antiretroviral therapy
    Ruimin Tan
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35294 0022, USA
    J Acquir Immune Defic Syndr 47:553-8. 2008
    ..The prognostic significance of a response to highly active antiretroviral therapy (HAART) that is immunologically and virologically discordant is not well understood...
  27. ncbi request reprint Exploration of an automated approach for receiving patient feedback after outpatient acute care visits
    Eta S Berner
    University of Alabama at Birmingham UAB, Birmingham, AL, USA
    J Gen Intern Med 29:1105-12. 2014
    ..To improve and learn from patient outcomes, particularly under new care models such as Accountable Care Organizations and Patient-Centered Medical Homes, requires establishing systems for follow-up and feedback...
  28. pmc Viremia copy-years predicts mortality among treatment-naive HIV-infected patients initiating antiretroviral therapy
    Michael J Mugavero
    Department of Medicine, Division of Infectious Diseases, University of Alabama, Birmingham, AL, USA
    Clin Infect Dis 53:927-35. 2011
    ..We evaluated the cumulative effect of exposure to HIV replication on mortality following initiation of combination antiretroviral therapy (ART)...
  29. pmc Pain is independently associated with impaired physical function in HIV-infected patients
    Jessica S Merlin
    Division of Infectious Diseases, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA Division of Gerontology, Geriatrics, and Palliative Care, Department of Medicine, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Pain Med 14:1985-93. 2013
    ..The objective of this study was to investigate the relationship of pain, a modifiable condition, to functional impairment in HIV-infected patients, independent of mood disorders and substance abuse...
  30. pmc Underutilization of aspirin for primary prevention of cardiovascular disease among HIV-infected patients
    Greer A Burkholder
    Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Clin Infect Dis 55:1550-7. 2012
    ..However, little is known about HIV provider practices regarding aspirin (ASA) for primary prevention of CVD...
  31. pmc Comparative Effectiveness and Toxicity of Statins Among HIV-Infected Patients
    Sudershan Singh
    Department of Medicine, University of Washington, Seattle, WA 98104, USA
    Clin Infect Dis 52:387-95. 2011
    ..Little is known about the comparative effectiveness of statins among human immunodeficiency virus (HIV)-infected patients. This study compared the effectiveness and toxicity of statins among HIV-infected patients in clinical care...
  32. pmc Routine, self-administered, touch-screen, computer-based suicidal ideation assessment linked to automated response team notification in an HIV primary care setting
    Sarah T Lawrence
    Department of Internal Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Clin Infect Dis 50:1165-73. 2010
    ..We sought to implement routine screening of suicidal ideation and associated conditions using computerized patient-reported outcome (PRO) assessments...
  33. pmc Medication possession ratio predicts antiretroviral regimens persistence in Peru
    Jorge L Salinas
    Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 8:e76323. 2013
    ..We modeled the impact of multiple measurements of antiretroviral treatment (ART) adherence on antiretroviral treatment outcomes in Peru...
  34. pmc Evaluation of the single-item self-rating adherence scale for use in routine clinical care of people living with HIV
    B J Feldman
    Department of Medicine, Harborview Medical Center, University of Washington, 325 9th Ave, Box 359931, Seattle, WA 98104, USA
    AIDS Behav 17:307-18. 2013
    ..These results and the SRSI's low patient burden suggest its routine use could be helpful for assessing adherence in clinical care and should be more widespread, particularly where more complex instruments may be impractical...
  35. pmc Predictive accuracy of the Veterans Aging Cohort Study index for mortality with HIV infection: a North American cross cohort analysis
    Amy C Justice
    Department of Internal Medicine, Yale University and the Veterans Affairs Healthcare System, West Haven, CT 06516, USA
    J Acquir Immune Defic Syndr 62:149-63. 2013
    ....
  36. pmc Short communication routine HIV testing in the emergency department: assessment of patient perceptions
    D Scott Batey
    Department of Internal Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, USA
    AIDS Res Hum Retroviruses 28:352-6. 2012
    ..These data are of particular benefit to decision makers considering the addition of routine HIV testing in EDs...
  37. ncbi request reprint Failure to establish HIV care: characterizing the "no show" phenomenon
    Michael J Mugavero
    Division of Infectious Diseases and International Health, Department of Medicine, University of Alabama at Birmingham, USA
    Clin Infect Dis 45:127-30. 2007
    ....
  38. pmc New syphilis cases and concurrent STI screening in a southeastern U.S. HIV clinic: a call to action
    Cynthia W Baffi
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
    AIDS Patient Care STDS 24:23-9. 2010
    ..These low rates are concerning as concurrent sexually transmitted infections (STIs) increase risk for HIV transmission. HIV care provider education with emphasis on STI testing in the setting of incident syphilis is key in prevention...
  39. ncbi request reprint Late diagnosis, delayed presentation and late presentation in HIV: proposed definitions, methodological considerations and health implications
    Michael Kozak
    Division of Infectious Diseases, Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
    Antivir Ther 18:17-23. 2013
    ....
  40. pmc Risk factors for chronic kidney disease in a large cohort of HIV-1 infected individuals initiating antiretroviral therapy in routine care
    Robert C Kalayjian
    Metro Health Medical Center, Cleveland, Ohio, USA
    AIDS 26:1907-15. 2012
    ....
  41. doi request reprint Prevalence, incidence, and recurrence of oral lesions among HIV-infected patients on HAART in Alabama: a two-year longitudinal study
    Irene M Tamí-Maury
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
    South Med J 104:561-6. 2011
    ..Our aim was to quantify prevalence, incidence, and recurrence of oral lesions (OL) among a population in the Southeast...
  42. pmc A qualitative assessment of internal medicine resident perceptions of graduate medical education following implementation of the 2011 ACGME duty hour standards
    Christa R Nevin
    University of Alabama at Birmingham, 845 19th Street South, BBRB 220B, Birmingham, AL 35294, USA
    BMC Med Educ 14:84. 2014
    ..We sought to investigate the impact of these restrictions on graduate medical education among internal medicine residents...
  43. pmc Closing the Feedback Loop: An Interactive Voice Response System to Provide Follow-up and Feedback in Primary Care Settings
    James H Willig
    University of Alabama at Birmingham, 1720 Second Ave South, Birmingham, AL, 35294, USA
    J Med Syst 37:9905. 2013
    ..With proper attention to design and development, modular follow-up and feedback systems can be integrated into existing EMR systems providing the benefits of IVRS follow-up to patients and providers across diverse practice settings...