Research Topics
Species | Kelly S WilliamsonSummaryAffiliation: University of Oklahoma Health Sciences Center Country: USA Publications
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Detail Information
Publications
HPLC-PFD determination of priority pollutant PAHs in water, sediment, and semipermeable membrane devicesKelly S Williamson
Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
Chemosphere 49:703-15. 2002..The focus of this publication is to examine the enrichment techniques and the analytical methodologies used in the isolation, characterization, and quantitation of 15 PPPAHs in different sample matrices...- Sequestration of priority pollutant PAHs from sediment pore water employing semipermeable membrane devicesKelly S Williamson
Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
Chemosphere 49:717-29. 2002..The focus of this publication is to demonstrate the ability to sequester environmental contaminants, specifically PPPAHs, from sediment pore water using SPMDs and two different types of fortified sediment... - Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosisKenneth Hensley
Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK 73104, USA
Neurobiol Dis 14:74-80. 2003..Our data support a model wherein TNFalpha acts as a principal driver for neuroinflammation, while several co-stimulating cytokines and chemokines act to potentiate the TNFalpha effects... - New perspectives on vitamin E: gamma-tocopherol and carboxyelthylhydroxychroman metabolites in biology and medicineKenneth Hensley
Free Radical Biology and Aging Research Program, Oklahoma Medical Reserach Foundation, Oklahoma City, OK 73104, USA
Free Radic Biol Med 36:1-15. 2004..The data argue for thorough experimental and epidemiological reappraisal of desmethyl tocopherols, especially within the contexts of cardiovascular disease and cancer biology... - On the relation of oxidative stress to neuroinflammation: lessons learned from the G93A-SOD1 mouse model of amyotrophic lateral sclerosisKenneth Hensley
Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Baltimore, Maryland, USA
Antioxid Redox Signal 8:2075-87. 2006..This review summarizes what has been learned to date from studies of mutant SOD1 transgenic animals and demonstrates that the G93A-SOD1 mouse in particular is a robust laboratory for the study of neuroinflammation and redox biochemistry... - The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor alpha activation of microglia and extends survival of G93A-SOD1 transgenic miceMelinda West
Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 73104, USA
J Neurochem 91:133-43. 2004..Thus, TNFalpha antagonists and especially 5LOX inhibitors might offer new opportunities for treatment of ALS... 
Antioxidants in central nervous system diseases: preclinical promise and translational challengesChandrashekhar D Kamat
Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
J Alzheimers Dis 15:473-93. 2008....- The nitration product 5-nitro-gamma-tocopherol is increased in the Alzheimer brainKelly S Williamson
Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK 73104, USA
Nitric Oxide 6:221-7. 2002..The findings are discussed in reference to the neuroinflammatory hypothesis of AD and the possible role of gamma-tocopherol as a major lipid-phase scavenger of reactive nitrogen species... - A survey of sesamin and composition of tocopherol variability from seeds of eleven diverse sesame (Sesamum indicum L.) genotypes using HPLC-PAD-ECDKelly S Williamson
Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA
Phytochem Anal 19:311-22. 2008..Statistical analysis was conducted and significant differences were observed among the 11 different sesame genotypes. This suggests that genetic, environmental and geographical factors influence sesamin and desmethyl tocopherol content... - Identification of lanthionine synthase C-like protein-1 as a prominent glutathione binding protein expressed in the mammalian central nervous systemCharlotte H Y Chung
Oklahoma Medical Research Foundation, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma 73118, USA
Biochemistry 46:3262-9. 2007..These results indicate LanCL1 is a glutathione binding protein possibly significant to neurodegenerative disease... - HPLC-electrochemical detection of tocopherol products as indicators of reactive nitrogen intermediatesKenneth Hensley
Oklahoma Medical Research Foundation, Free Radical Biology and Aging Research Program, Oklahoma City, OK 73104, USA
Methods Enzymol 396:171-82. 2005.... - Bacillus anthracis peptidoglycan stimulates an inflammatory response in monocytes through the p38 mitogen-activated protein kinase pathwayMarybeth Langer
Immunobiology and Cancer Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA
PLoS ONE 3:e3706. 2008..Given the high bacterial burden in pulmonary anthrax, these findings suggest that the inflammatory events associated with peptidoglycan may play an important role in anthrax pathogenesis...