Matthew A Williams

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. Williams M. Instant recall: a key role for effector-phenotype CD8⁺ memory T cells in immune protection. Immunity. 2013;38:1090-1 pubmed publisher
  2. Snook J, Kim C, Williams M. TCR signal strength controls the differentiation of CD4+ effector and memory T cells. Sci Immunol. 2018;3: pubmed publisher
    ..We conclude that strong TCR signals during early T cell activation favor terminal TH1 differentiation over long-term TH1 and T follicular helper cell memory responses. ..
  3. Williams M, Ravkov E, Bevan M. Rapid culling of the CD4+ T cell repertoire in the transition from effector to memory. Immunity. 2008;28:533-45 pubmed publisher
    ..These results support a model in which CD4+ T cell memory differentiation and longevity depend on the strength of the TCR signal during the primary response. ..
  4. Meek S, Williams M. IFN-Gamma-Dependent and Independent Mechanisms of CD4⁺ Memory T Cell-Mediated Protection from Listeria Infection. Pathogens. 2018;7: pubmed publisher
    ..Overall, we conclude that protection mediated by CD4⁺ memory T cells from heterologous Listeria challenge is most directly dependent on TNF, whereas IFNγ only plays a minor role. ..