Research Topics
| Mark J WilliamsSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Publications
The role of acetylcholine in cocaine addictionMark J Williams
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 8564, USA
Neuropsychopharmacology 33:1779-97. 2008....
Dissection of hypothalamic-pituitary-adrenal axis pathology in 1-month-abstinent alcohol-dependent men, part 2: response to ovine corticotropin-releasing factor and naloxoneBryon Adinoff
Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75216, USA
Alcohol Clin Exp Res 29:528-37. 2005..In addition, pulsatile characteristics of corticotropin and cortisol were assessed over a 12-hr period (0800 to 2000 hr)...
Adrenocortical and pituitary glucocorticoid feedback in abstinent alcohol-dependent womenBryon Adinoff
Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, USA
Alcohol Clin Exp Res 34:915-24. 2010....
Altered neural cholinergic receptor systems in cocaine-addicted subjectsBryon Adinoff
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 8564, USA
Neuropsychopharmacology 35:1485-99. 2010..Cholinergic systems may offer a pharmacologic target for cocaine addiction treatment...
Sex differences in medial and lateral orbitofrontal cortex hypoperfusion in cocaine-dependent men and womenBryon Adinoff
Department of Psychiatry, University of Texas Southwestern Medical Center, and VA North Texas Health Care System, Dallas, Texas 75390 8564, USA
Gend Med 3:206-22. 2006..Hypoperfusion of the orbitofrontal cortex (OFC) has previously been reported in individuals addicted to cocaine and has been posited as a biological mediator of relapse due to impulsivity or impaired decision making...
Neural response to lidocaine in healthy subjectsBryon Adinoff
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, United States
Psychiatry Res 173:135-42. 2009..These findings suggest that lidocaine can be safely used to assess sodium channel function in persons with addictive and other psychiatric disorders...
Time to Relapse Questionnaire (TRQ): a measure of sudden relapse in substance dependenceBryon Adinoff
UT Southwestern Medical Center at Dallas, Psychiatry, Dallas, Texas 75390 8564, USA
Am J Drug Alcohol Abuse 36:140-9. 2010..Relapse may occur suddenly, following a short period of craving, or after extended consideration. The time to relapse may reveal underlying mechanisms of relapse and have important implications for treatment...
Dissection of hypothalamic-pituitary-adrenal axis pathology in 1-month-abstinent alcohol-dependent men, part 1: adrenocortical and pituitary glucocorticoid responsivenessBryon Adinoff
Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75216, USA
Alcohol Clin Exp Res 29:517-27. 2005....
Gender differences in limbic responsiveness, by SPECT, following a pharmacologic challenge in healthy subjectsBryon Adinoff
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Neuroimage 18:697-706. 2003..Studies assessing pharmacologic challenges of limbic system structures should consider gender as a critical variable in assessing biologic responsiveness...
Increased salivary cortisol concentrations during chronic alcohol intoxication in a naturalistic clinical sample of menBryon Adinoff
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, USA
Alcohol Clin Exp Res 27:1420-7. 2003..Although moderate levels of acute alcohol ingestion are reported to produce an increase in cortisol levels, it is uncertain whether cortisol remains persistently increased during long-term chronic intoxication...
The development and psychometric validation of the central sensitization inventoryTom G Mayer
Department of Orthopedic Surgery, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA
Pain Pract 12:276-85. 2012..001). Taken together, these 2 studies demonstrate the psychometric strength, clinical utility, and the initial construct validity of the CSI in evaluating CS-related clinical symptoms in chronic pain populations. ..
Impulsivity, neural deficits, and the addictions: the "oops" factor in relapseBryon Adinoff
Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas and VA North Texas Health Care System, Dallas, TX 75390 8564, USA
J Addict Dis 26:25-39. 2007..Empirical investigations documenting the hypothesized relationship between specific deficits in impulsive behaviors, coupled with their neurobiological correlates, and relapse should be the focus of future studies...
Regional cerebral blood flow in female cocaine-addicted subjects following limbic activationBryon Adinoff
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Drug Alcohol Depend 71:255-68. 2003..In this study, we assessed the limbic rCBF response to procaine in female cocaine-addicted subjects (n=10) and female controls (n=10)...
