Cecilia Williams

Summary

Affiliation: University of Houston
Country: USA

Publications

  1. pmc Knockdown of SF-1 and RNF31 affects components of steroidogenesis, TGFβ, and Wnt/β-catenin signaling in adrenocortical carcinoma cells
    Anna Ehrlund
    Center for Biosciences, Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
    PLoS ONE 7:e32080. 2012
  2. pmc Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expression
    Cecilia Williams
    Department of Biology and Biochemistry, Center for Nuclear Receptors and Cell Signaling, University of Houston, 3013 Science and Engineering Research Center, Houston, TX 77204, USA
    Breast Cancer Res 11:R26. 2009
  3. doi request reprint Estrogen receptor β expression induces changes in the microRNA pool in human colon cancer cells
    Karin Edvardsson
    Department of Biology and Biochemistry, Center for Nuclear Receptors and Cell Signaling, University of Houston, Houston, TX 77204, USA
    Carcinogenesis 34:1431-41. 2013
  4. doi request reprint Interplay between AP-1 and estrogen receptor α in regulating gene expression and proliferation networks in breast cancer cells
    Karin Dahlman-Wright
    Department of Biosciences and Nutrition, Novum, Karolinska Institutet, S 141 83 Huddinge, Sweden
    Carcinogenesis 33:1684-91. 2012
  5. doi request reprint Estrogen receptor β induces antiinflammatory and antitumorigenic networks in colon cancer cells
    Karin Edvardsson
    Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, Texas 77204 5056, USA
    Mol Endocrinol 25:969-79. 2011
  6. pmc Estrogen receptors β1 and β2 have opposing roles in regulating proliferation and bone metastasis genes in the prostate cancer cell line PC3
    Prasenjit Dey
    Department of Biology and Biochemistry, Center for Nuclear Receptors and Cell Signaling, University of Houston, Houston, Texas 77204 5056, USA
    Mol Endocrinol 26:1991-2003. 2012
  7. doi request reprint MicroRNA-regulated gene networks during mammary cell differentiation are associated with breast cancer
    Eylem Aydogdu
    Department of Biology and Biochemistry, Center for Nuclear Receptors and Cell Signaling, University of Houston, Houston, TX 77204, USA
    Carcinogenesis 33:1502-11. 2012
  8. doi request reprint Estradiol-activated estrogen receptor α does not regulate mature microRNAs in T47D breast cancer cells
    Anne Katchy
    Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, TX, USA
    J Steroid Biochem Mol Biol 128:145-53. 2012
  9. doi request reprint Coexposure to phytoestrogens and bisphenol a mimics estrogenic effects in an additive manner
    Anne Katchy
    Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, Texas 77204 5056
    Toxicol Sci 138:21-35. 2014
  10. doi request reprint Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells
    Johan Hartman
    Department of Biosciences and Nutrition, Karolinska Institutet, Novum, Huddinge, Sweden
    Cancer Res 69:6100-6. 2009

Collaborators

Detail Information

Publications12

  1. pmc Knockdown of SF-1 and RNF31 affects components of steroidogenesis, TGFβ, and Wnt/β-catenin signaling in adrenocortical carcinoma cells
    Anna Ehrlund
    Center for Biosciences, Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
    PLoS ONE 7:e32080. 2012
    ..Finally, the SF-1 gene profile can be used to distinguish malignant from benign adrenocortical tumors, a finding that implicates SF-1 in the development of malignant adrenocortical carcinoma...
  2. pmc Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expression
    Cecilia Williams
    Department of Biology and Biochemistry, Center for Nuclear Receptors and Cell Signaling, University of Houston, 3013 Science and Engineering Research Center, Houston, TX 77204, USA
    Breast Cancer Res 11:R26. 2009
    ..To determine a possible association between mammary stem cells and breast cancer, a detailed characterization of the transcriptome in mammary stem cells is essential...
  3. doi request reprint Estrogen receptor β expression induces changes in the microRNA pool in human colon cancer cells
    Karin Edvardsson
    Department of Biology and Biochemistry, Center for Nuclear Receptors and Cell Signaling, University of Houston, Houston, TX 77204, USA
    Carcinogenesis 34:1431-41. 2013
    ..Our work contributes novel data of ERβ and miRNA in the colon. Elucidating the mechanism of ERβ and biomarkers of its activity has significant potential to impact colon cancer prevention and treatment. ..
  4. doi request reprint Interplay between AP-1 and estrogen receptor α in regulating gene expression and proliferation networks in breast cancer cells
    Karin Dahlman-Wright
    Department of Biosciences and Nutrition, Novum, Karolinska Institutet, S 141 83 Huddinge, Sweden
    Carcinogenesis 33:1684-91. 2012
    ..Knockdown of PKIB results in robust growth suppression of breast cancer cells. Collectively, our findings support c-Fos as a critical factor that governs estrogen-dependent gene expression and breast cancer proliferation programs...
  5. doi request reprint Estrogen receptor β induces antiinflammatory and antitumorigenic networks in colon cancer cells
    Karin Edvardsson
    Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, Texas 77204 5056, USA
    Mol Endocrinol 25:969-79. 2011
    ..We propose that enhancing ERβ action has potential as a novel therapeutic approach for prevention and/or treatment of colon cancer...
  6. pmc Estrogen receptors β1 and β2 have opposing roles in regulating proliferation and bone metastasis genes in the prostate cancer cell line PC3
    Prasenjit Dey
    Department of Biology and Biochemistry, Center for Nuclear Receptors and Cell Signaling, University of Houston, Houston, Texas 77204 5056, USA
    Mol Endocrinol 26:1991-2003. 2012
    ..Thus, in prostate cancer cells, ERβ2 has oncogenic abilities that are in strong contrast to the tumor-suppressing effects of ERβ1...
  7. doi request reprint MicroRNA-regulated gene networks during mammary cell differentiation are associated with breast cancer
    Eylem Aydogdu
    Department of Biology and Biochemistry, Center for Nuclear Receptors and Cell Signaling, University of Houston, Houston, TX 77204, USA
    Carcinogenesis 33:1502-11. 2012
    ..Our studies propose EphA2 as a novel and important target gene for miR-200a. In conclusion, we present evidentiary data on how miRNAs are involved in mammary cell differentiation and indicate their related roles in breast cancer...
  8. doi request reprint Estradiol-activated estrogen receptor α does not regulate mature microRNAs in T47D breast cancer cells
    Anne Katchy
    Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, TX, USA
    J Steroid Biochem Mol Biol 128:145-53. 2012
    ....
  9. doi request reprint Coexposure to phytoestrogens and bisphenol a mimics estrogenic effects in an additive manner
    Anne Katchy
    Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, Texas 77204 5056
    Toxicol Sci 138:21-35. 2014
    ..This study accentuates that coexposure to BPA and soy-based phytoestrogens results in additive estrogenic effects, and may contribute to estrogen-linked diseases, including breast cancer. ..
  10. doi request reprint Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells
    Johan Hartman
    Department of Biosciences and Nutrition, Karolinska Institutet, Novum, Huddinge, Sweden
    Cancer Res 69:6100-6. 2009
    ..Furthermore, this ERbeta-mediated cell cycle repression is dependent on functional ERE binding...
  11. doi request reprint Support of a bi-faceted role of estrogen receptor β (ERβ) in ERα-positive breast cancer cells
    Philip Jonsson
    Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, 3605 Cullen Blvd, Houston, Texas 77204 5056, USA
    Endocr Relat Cancer 21:143-60. 2014
    ..Our study is important because it provides a deeper understanding of ERβ's role in breast tumors that coexpress both receptors and supports an emerging bi-faceted role of ERβ. ..
  12. pmc The two-pore domain potassium channel KCNK5: induction by estrogen receptor alpha and role in proliferation of breast cancer cells
    Claudia P Alvarez-Baron
    Department of Biology and Biochemistry, University of Houston, Houston, Texas 77204 5001, USA
    Mol Endocrinol 25:1326-36. 2011
    ..KCNK5 may therefore represent a useful target for treatment, for example, of tamoxifen-resistant breast cancer...