Brian A Williams

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Diplopia: a complication of dural puncture
    Isuta Nishio
    Department of Anesthesiology, University of Pittsburgh School of Medicine, Pennsylvania, USA
    Anesthesiology 100:158-64. 2004
  2. pmc Diabetes mellitus and subclinical neuropathy: a call for new paths in peripheral nerve block research
    Brian A Williams
    Anesthesiology 109:361-2. 2008
  3. ncbi request reprint Seeds, trees, and shade-personal experience in research career development
    Brian A Williams
    Reg Anesth Pain Med 32:545-6. 2007
  4. ncbi request reprint Electrical stimulation: an important force behind the growth of regional anesthesia
    Brian A Williams
    Can J Anaesth 54:585-6; author reply 586-7. 2007
  5. ncbi request reprint Skin reactions at the femoral perineural catheter insertion site: retrospective summary of a randomized clinical trial
    Brian A Williams
    Anesth Analg 104:1309-10. 2007
  6. pmc Forecast for perineural analgesia procedures for ambulatory surgery of the knee, foot, and ankle: applying patient-centered paradigm shifts
    Brian A Williams
    University of Pittsburgh, Pennsylvania 15261, USA
    Int Anesthesiol Clin 50:126-42. 2012
  7. ncbi request reprint Process analysis in outpatient knee surgery: effects of regional and general anesthesia on anesthesia-controlled time
    B A Williams
    Same Day Surgical Services, University of Pittsburgh Medical Center, PA 15213 2582, USA
    Anesthesiology 93:529-38. 2000
  8. ncbi request reprint Reduction of verbal pain scores after anterior cruciate ligament reconstruction with 2-day continuous femoral nerve block: a randomized clinical trial
    Brian A Williams
    Department of Anesthesiology, University of Pittsburgh Medical Center, 2000 Mary Street, Pittsburgh, PA 15203, USA
    Anesthesiology 104:315-27. 2006
  9. pmc General health and knee function outcomes from 7 days to 12 weeks after spinal anesthesia and multimodal analgesia for anterior cruciate ligament reconstruction
    Brian A Williams
    Department of Anesthesiology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Anesth Analg 108:1296-302. 2009
  10. pmc Neurotoxicity of adjuvants used in perineural anesthesia and analgesia in comparison with ropivacaine
    Brian A Williams
    University of Pittsburgh School of Medicine, Department of Anesthesiology, Pittsburgh, PA, USA
    Reg Anesth Pain Med 36:225-30. 2011

Research Grants

Detail Information

Publications51

  1. ncbi request reprint Diplopia: a complication of dural puncture
    Isuta Nishio
    Department of Anesthesiology, University of Pittsburgh School of Medicine, Pennsylvania, USA
    Anesthesiology 100:158-64. 2004
  2. pmc Diabetes mellitus and subclinical neuropathy: a call for new paths in peripheral nerve block research
    Brian A Williams
    Anesthesiology 109:361-2. 2008
  3. ncbi request reprint Seeds, trees, and shade-personal experience in research career development
    Brian A Williams
    Reg Anesth Pain Med 32:545-6. 2007
  4. ncbi request reprint Electrical stimulation: an important force behind the growth of regional anesthesia
    Brian A Williams
    Can J Anaesth 54:585-6; author reply 586-7. 2007
  5. ncbi request reprint Skin reactions at the femoral perineural catheter insertion site: retrospective summary of a randomized clinical trial
    Brian A Williams
    Anesth Analg 104:1309-10. 2007
  6. pmc Forecast for perineural analgesia procedures for ambulatory surgery of the knee, foot, and ankle: applying patient-centered paradigm shifts
    Brian A Williams
    University of Pittsburgh, Pennsylvania 15261, USA
    Int Anesthesiol Clin 50:126-42. 2012
    ..Ongoing research in this direction seems to represent the next major advancement in the subspecialty, being distinguished from refinement research involving strictly techniques and technology...
  7. ncbi request reprint Process analysis in outpatient knee surgery: effects of regional and general anesthesia on anesthesia-controlled time
    B A Williams
    Same Day Surgical Services, University of Pittsburgh Medical Center, PA 15213 2582, USA
    Anesthesiology 93:529-38. 2000
    ..The authors hypothesized that, using the anesthesia care team model, RA would be associated with reduced anesthesia-controlled time compared with general anesthesia (GA) alone or combined general-regional anesthesia (GA-RA)...
  8. ncbi request reprint Reduction of verbal pain scores after anterior cruciate ligament reconstruction with 2-day continuous femoral nerve block: a randomized clinical trial
    Brian A Williams
    Department of Anesthesiology, University of Pittsburgh Medical Center, 2000 Mary Street, Pittsburgh, PA 15203, USA
    Anesthesiology 104:315-27. 2006
    ..In the current study, the authors prospectively determined the effect of continuous femoral nerve block on a numeric rating scale (NRS) of pain intensity with movement for 7 postoperative days...
  9. pmc General health and knee function outcomes from 7 days to 12 weeks after spinal anesthesia and multimodal analgesia for anterior cruciate ligament reconstruction
    Brian A Williams
    Department of Anesthesiology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Anesth Analg 108:1296-302. 2009
    ..We now report the prospectively collected general health and knee function outcomes in the 7 days to 12 wk after surgery in these same patients...
  10. pmc Neurotoxicity of adjuvants used in perineural anesthesia and analgesia in comparison with ropivacaine
    Brian A Williams
    University of Pittsburgh School of Medicine, Department of Anesthesiology, Pittsburgh, PA, USA
    Reg Anesth Pain Med 36:225-30. 2011
    ..Therefore, the impact of these adjuvants on ropivacaine (R)-induced death of isolated sensory neurons was assessed...
  11. ncbi request reprint Nausea and vomiting after outpatient ACL reconstruction with regional anesthesia: are lumbar plexus blocks a risk factor?
    Brian A Williams
    Same Day Surgical Services, University of Pittsburgh Medical Center, Pittsburgh, PA 15203, USA
    J Clin Anesth 16:276-81. 2004
    ....
  12. ncbi request reprint Economics of nerve block pain management after anterior cruciate ligament reconstruction: potential hospital cost savings via associated postanesthesia care unit bypass and same-day discharge
    Brian A Williams
    Same Day Surgical Services, University of Pittsburgh Medical Center, Pennsylvania 15203, USA
    Anesthesiology 100:697-706. 2004
    ..In this study, the authors examine the associations of nerve block analgesia for these patients and its associated reductions in PACU use, hospital admission, and hospital costs...
  13. ncbi request reprint Routine multimodal antiemesis including low-dose perphenazine in an ambulatory surgery unit of a university hospital: a 10-year history. Supplement to: Eliminating postoperative nausea and vomiting in outpatient surgery with multimodal strategies includin
    Brian A Williams
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    ScientificWorldJournal 7:978-86. 2007
    ..e., increase PACU bypass), reduce the need for any nursing interventions for postoperative nausea and/or vomiting (PONV), and influence the extent to which any variable costs of postoperative nursing care are reduced...
  14. ncbi request reprint PACU bypass after outpatient knee surgery is associated with fewer unplanned hospital admissions but more phase II nursing interventions
    Brian A Williams
    Anesthesiology, Department of Same Day Surgical Services, University of Pittsburgh Medical Center, Pennsylvania 15261, USA
    Anesthesiology 97:981-8. 2002
    ..We report PACU bypass rates using these criteria, and the extent to which PACU bypass was associated with (1) required nursing interventions in the step-down recovery unit, and (2) successful same-day discharge...
  15. ncbi request reprint Femoral-sciatic nerve blocks for complex outpatient knee surgery are associated with less postoperative pain before same-day discharge: a review of 1,200 consecutive cases from the period 1996-1999
    Brian A Williams
    University of Pittsburgh, A 1305 Scaife Hall, Pittsburgh, Pennsylvania, 15261, USA
    Anesthesiology 98:1206-13. 2003
    ..The aim of this report is to demonstrate differences in pain and unplanned hospital admission associated with surgical complexity and nerve blocks used...
  16. pmc Nausea, vomiting, sleep, and restfulness upon discharge home after outpatient anterior cruciate ligament reconstruction with regional anesthesia and multimodal analgesia/antiemesis
    Brian A Williams
    Department of Anesthesiology, University of Pittsburgh, Pittsburgh, PA, USA
    Reg Anesth Pain Med 32:193-202. 2007
    ..The outcomes specifically addressed in this report are nausea, vomiting, and retching (NVR) and quality of sleep/difficulty falling asleep/daytime restfulness...
  17. pmc Health-related quality of life after tricompartment knee arthroplasty with and without an extended-duration continuous femoral nerve block: a prospective, 1-year follow-up of a randomized, triple-masked, placebo-controlled study
    Brian M Ilfeld
    Department of Anesthesiology, UCSD Center for Pain Medicine, 9300 Campus Point Dr MC 7651, La Jolla, CA 92037 7651, USA
    Anesth Analg 108:1320-5. 2009
    ..However, it remains unknown if the extended infusion improves subsequent health-related quality of life between 7 days and 12 mo...
  18. pmc Rebound pain scores as a function of femoral nerve block duration after anterior cruciate ligament reconstruction: retrospective analysis of a prospective, randomized clinical trial
    Brian A Williams
    Department of Anesthesiology, UPMC South Side, University of Pittsburgh, Pittsburgh, PA, USA
    Reg Anesth Pain Med 32:186-92. 2007
    ..In the current study, we determined rebound pain scores in autograft ACLR outpatients after nerve block analgesia resolved...
  19. ncbi request reprint Eliminating postoperative nausea and vomiting in outpatient surgery with multimodal strategies including low doses of nonsedating, off-patent antiemetics: is "zero tolerance" achievable?
    Susan J Skledar
    University of Pittsburgh School of Pharmacy, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    ScientificWorldJournal 7:959-77. 2007
    ..If available, a consultation for therapeutic acupuncture procedure is ordered. Our approach toward "zero tolerance" of PONV emphasizes liberal identification of and prophylaxis against common risks...
  20. ncbi request reprint Anesthesia and postoperative analgesia: outcomes following orthopedic surgery
    Jacques E Chelly
    Department of Anesthesiology, The University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Orthopedics 26:s865-71. 2003
    ..Regional techniques are usually part of a multimodal strategy that includes both pharmacological and nonpharmacological approaches to pain management...
  21. ncbi request reprint Antiemetics in outpatient regional anesthesia for invasive orthopedic surgery
    Michael L Kentor
    Department of Anesthesiology, University of Pittsburgh, PA 15203, USA
    Int Anesthesiol Clin 43:205-13. 2005
  22. pmc Adverse outcomes associated with nerve stimulator-guided and ultrasound-guided peripheral nerve blocks by supervised trainees: update of a single-site database
    Steven L Orebaugh
    Department of Anesthesiology, University of Pittsburgh School of Medicine, UPMC Southside Mercy Ambulatory Surgical Center, 2000 Mary Street, Pittsburgh, PA 15203, USA
    Reg Anesth Pain Med 37:577-82. 2012
    ....
  23. doi request reprint Future considerations for pharmacologic adjuvants in single-injection peripheral nerve blocks for patients with diabetes mellitus
    Brian A Williams
    Department of Anesthesiology, University of Pittsburgh Medical Center South Side, University of Pittsburgh, Pittsburgh, PA 15203, USA
    Reg Anesth Pain Med 34:445-57. 2009
    ....
  24. ncbi request reprint Regional anesthesia procedures for ambulatory knee surgery: effects on in-hospital outcomes
    Brian A Williams
    Department of Anesthesiology, University of Pittsburgh, Pennsylvania 15203, USA
    Int Anesthesiol Clin 43:153-60. 2005
  25. ncbi request reprint The 8-item Short-Form Health Survey and the physical comfort composite score of the quality of recovery 40-item scale provide the most responsive assessments of pain, physical function, and mental function during the first 4 days after ambulatory knee sur
    James E Bost
    Center for Research on Health Care, and Department of Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Anesth Analg 105:1693-700, table of contents. 2007
    ..The objective was to provide a robust psychometric basis for outcome survey selection for surgical outpatients undergoing regional anesthesia without general anesthesia...
  26. doi request reprint Aprepitant plus ondansetron compared with ondansetron alone in reducing postoperative nausea and vomiting in ambulatory patients undergoing plastic surgery
    Manuel C Vallejo
    Department of Anesthesiology, Magee Womens Hospital of the University of Pittsburgh Medical Center, 300 Halket Street, Pittsburgh, PA 15213, USA
    Plast Reconstr Surg 129:519-26. 2012
    ..This study evaluated the efficacy of a neurokinin-1 receptor antagonist (aprepitant) in reducing postoperative symptoms for up to 48 hours in patients undergoing outpatient plastic surgery...
  27. doi request reprint Diabetes mellitus, independent of body mass index, is associated with a "higher success" rate for supraclavicular brachial plexus blocks
    Ralf E Gebhard
    Department of Anesthesiology, University of Miami Miller School of Medicine, Miami, FL 15203, USA
    Reg Anesth Pain Med 34:404-7. 2009
    ..The authors retrospectively evaluated the influence of diabetes, body mass index (BMI), age, and sex on the success of supraclavicular block (SCB) placed with a landmark-based paresthesia technique...
  28. doi request reprint Aprepitant in a multimodal approach for prevention of postoperative nausea and vomiting in high-risk patients: is there such a thing as "too many modalities"?
    John J Hache
    University of Pittsburgh Department of Anesthesiology, Liliane S Kaufmann Building, 3471 Fifth Avenue, Suite 910, Pittsburgh, PA 15213, USA
    ScientificWorldJournal 9:291-9. 2009
    ..However, there may be the potential that too many unique antiemetic mechanisms combined with preoperative aprepitant may actually increase the incidence of perioperative nausea...
  29. ncbi request reprint For outpatient rotator cuff surgery, nerve block anesthesia provides superior same-day recovery over general anesthesia
    Admir Hadzic
    Department of Anesthesiology, St Luke s Roosevelt Hospital Center, College of Physicians and Surgeons, Columbia University, New York, New York 10025, USA
    Anesthesiology 102:1001-7. 2005
    ..The authors' goal was to compare nerve block with general anesthesia with respect to recovery profile and patient satisfaction after rotator cuff surgery...
  30. doi request reprint Adverse outcomes associated with stimulator-based peripheral nerve blocks with versus without ultrasound visualization
    Steven L Orebaugh
    University of Pittsburgh Medical Center South Side, PA 15203, USA
    Reg Anesth Pain Med 34:251-5. 2009
    ....
  31. pmc Hospitalization costs of total knee arthroplasty with a continuous femoral nerve block provided only in the hospital versus on an ambulatory basis: a retrospective, case-control, cost-minimization analysis
    Brian M Ilfeld
    Department of Anesthesiology, University of California San Diego, San Diego, CA, USA
    Reg Anesth Pain Med 32:46-54. 2007
    ..This study quantified the hospitalization costs for 10 TKA patients receiving ambulatory CFNB versus a matched cohort of 10 patients who received CFNB only during hospitalization...
  32. pmc Effect of adjuvant drugs on the action of local anesthetics in isolated rat sciatic nerves
    Eser Yilmaz-Rastoder
    Department of Anesthesiology and Center for Pain Research, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Reg Anesth Pain Med 37:403-9. 2012
    ....
  33. ncbi request reprint Hospital facilities and resource management: economic impact of a high-volume regional anesthesia program for outpatients
    Brian A Williams
    Department of Anesthesiology, University of Pittsburgh, Pennsylvania 15203, USA
    Int Anesthesiol Clin 43:43-51. 2005
  34. ncbi request reprint Regional anesthesia group practice in the university hospital setting and ambulatory/regional anesthesia clinical pathway formulation
    Brian A Williams
    Department of Anesthesiology, University of Pittsburgh, Pennsylvania 15203, USA
    Int Anesthesiol Clin 43:3-13. 2005
  35. doi request reprint Loss of extension following anterior cruciate ligament reconstruction: analysis of incidence and etiology using IKDC criteria
    Craig S Mauro
    Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Arthroscopy 24:146-53. 2008
    ....
  36. ncbi request reprint Ultrasound guidance with nerve stimulation reduces the time necessary for resident peripheral nerve blockade
    Steven L Orebaugh
    Department of Anesthesiology, UPMC Southside, University of Pittsburgh School of Medicine, Pittsburgh, PA 15203, USA
    Reg Anesth Pain Med 32:448-54. 2007
    ..Ultrasound guidance may affect the efficiency and effectiveness of nerve block. We examined the impact of ultrasound guidance on resident performance of peripheral nerve block in a regional anesthesia rotation...
  37. doi request reprint Brachial plexus anatomy: normal and variant
    Steven L Orebaugh
    University of Pittsburgh, UPMC South Side, 2000 Mary Street, Pittsburgh, PA 15203, USA
    ScientificWorldJournal 9:300-12. 2009
    ..The ability to explore anatomy at the bedside, with real-time ultrasonography, has improved our appreciation of brachial plexus anatomy as well...
  38. pmc Transient heat hyperalgesia during resolution of ropivacaine sciatic nerve block in the rat
    Lavinia M Kolarczyk
    Department of Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Reg Anesth Pain Med 36:220-4. 2011
    ..5% leads to transient heat hyperalgesia in rats independent of mechanical nociception. We also evaluated functional toxicity (eg, long-term hyperalgesia and/or tactile allodynia 2 weeks after injection)...
  39. ncbi request reprint Retrospective evaluation of unanticipated admissions and readmissions after same day surgery and associated costs
    Kim C Coley
    Center for Pharmacoinformatics and Outcomes Research, University of Pittsburgh School of Pharmacy, 921 Salk Hall, Pittsburgh, PA 15261, USA
    J Clin Anesth 14:349-53. 2002
    ..To determine the rate of unanticipated admissions and readmissions, and to characterize the associated reasons and costs...
  40. ncbi request reprint Regional anesthesia procedures for outpatient shoulder surgery
    Reginald E Julien
    Department of Anesthesiology, Health Science Center of Brooklyn, State University of New York, 11203, USA
    Int Anesthesiol Clin 43:167-75. 2005
  41. ncbi request reprint Making an ambulatory surgery centre suitable for regional anaesthesia
    Brian A Williams
    University of Pittsburgh Medical Center, Department of Anesthesiology, UPMC South Side, Pittsburgh, USA
    Best Pract Res Clin Anaesthesiol 16:175-94. 2002
    ..The remainder of the care process relies on teamwork among all healthcare providers and meaningful administrative support...
  42. doi request reprint Extrapyramidal symptoms following administration of oral perphenazine 4 or 8 mg: an 11-year retrospective analysis
    John P Henao
    From the Department of Anesthesiology, University of Pittsburgh Medical Center JPH, KAP, SLO, School of Pharmacy ABL, SJS, Department of Anesthesiology, University of Pittsburgh MAP, and Department of Anesthesiology, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, USA BAW John P Henao and Katherin A Peperzak are co lead authors for the article
    Eur J Anaesthesiol 31:231-5. 2014
    ..Chronic administration and high dose are known to cause extrapyramidal system (EPS) dysfunction at a frequency of 8%, but the incidence of acute EPS after a single 4 or 8 mg dose is unknown...
  43. doi request reprint Economics and practice management issues associated with acute pain management
    Dennis P Phillips
    Department of Anesthesiology, University of Pittsburgh Medical Center, Liliane S Kaufmann Building, 3471 Fifth Avenue Suite 910, Pittsburgh, PA 15213, USA
    Anesthesiol Clin 29:213-32. 2011
    ..Additional review and commentary address surgical site infections, cancer recurrence, blood transfusions, and chronic postsurgical pain...
  44. ncbi request reprint Development of a standardized peripheral nerve block procedure note form
    J C Gerancher
    Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1009, USA
    Reg Anesth Pain Med 30:67-71. 2005
    ..Our objective was to create a peripheral nerve block form based on key elements of literature evidence and on our own group consensus...
  45. ncbi request reprint Fast-track ambulatory anesthesia: impact on nursing workload when analgesia and antiemetic prophylaxis are near-optimal
    Brian A Williams
    Can J Anaesth 54:243-4. 2007
  46. ncbi request reprint The incidence of falls at home in patients with perineural femoral catheters: a retrospective summary of a randomized clinical trial
    Brian A Williams
    Anesth Analg 104:1002. 2007
  47. ncbi request reprint For outpatients, does regional anesthesia truly shorten the hospital stay, and how should we define postanesthesia care unit bypass eligibility?
    Brian A Williams
    Anesthesiology 101:3-6. 2004
  48. ncbi request reprint Continuous perineural infusions at home: narrowing the focus
    Jacques E Chelly
    Reg Anesth Pain Med 29:1-3. 2004
  49. ncbi request reprint Billing for outpatient regional anesthesia services in the United States
    Jennifer Greger
    Greater Houston Anesthesia, TX 77057 4817, USA
    Int Anesthesiol Clin 43:33-41. 2005
  50. ncbi request reprint A post hoc analysis of research study staffing: budgetary effects of the Health Insurance Portability and Accountability Act on research staff work hours during a prospective, randomized clinical trial
    Brian A Williams
    Anesthesiology 107:860-1. 2007
  51. ncbi request reprint Potential economic benefits of regional anesthesia for acute pain management: the need to study both inputs and outcomes
    Brian A Williams
    Reg Anesth Pain Med 31:95-9. 2006

Research Grants2

  1. Outcomes After ACL Reconstruction: Femoral Nerve Block
    Brian Williams; Fiscal Year: 2005
    ..The methods learned and the model developed herein will be the basis of future studies funded through the R01 mechanism. ..