Robert L Wilensky

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint Angiotensin-receptor blockers: revival of the systemic prevention of restenosis?
    Robert L Wilensky
    Hospital of the University of Pennsylvania, 3400 Spruce St, 9 Gates, Philadelphia, PA 19104, USA
    Cardiovasc Drugs Ther 17:63-73. 2003
  2. doi request reprint Lipoprotein-associated phospholipase A(2) and atherosclerosis
    Robert L Wilensky
    Cardiovascular Division, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Curr Opin Lipidol 20:415-20. 2009
  3. ncbi request reprint The molecular basis of vulnerable plaque: potential therapeutic role for immunomodulation
    Robert L Wilensky
    University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Curr Opin Cardiol 22:545-51. 2007
  4. ncbi request reprint Role of magnetic resonance and intravascular magnetic resonance in the detection of vulnerable plaques
    Robert L Wilensky
    Cardiovascular Division, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Am Coll Cardiol 47:C48-56. 2006
  5. pmc Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development
    Robert L Wilensky
    Hospital of the University of Pennsylvania, 3400 Spruce Street, 9 Gates, Philadelphia, Pennsylvania 19104, USA
    Nat Med 14:1059-66. 2008
  6. ncbi request reprint Relation of percutaneous coronary intervention of complex lesions to clinical outcomes (from the NHLBI Dynamic Registry)
    Robert L Wilensky
    Cardiovascular Division, University of Pennsylvania, Philadelphia 19104, USA
    Am J Cardiol 90:216-21. 2002
  7. doi request reprint Site-specific atherogenic gene expression correlates with subsequent variable lesion development in coronary and peripheral vasculature
    Emile R Mohler
    University of Pennsylvania, Philadelphia, PA 19104, USA
    Arterioscler Thromb Vasc Biol 28:850-5. 2008
  8. doi request reprint Diabetes reduces bone marrow and circulating porcine endothelial progenitor cells, an effect ameliorated by atorvastatin and independent of cholesterol
    Emile R Mohler
    Department of Medicine, Cardiovascular Division, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Cytometry A 75:75-82. 2009
  9. doi request reprint Vascular responses to drug-eluting and bare metal stents in diabetic/hypercholesterolemic and nonatherosclerotic porcine coronary arteries
    Raul Llano
    Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104, USA
    Circ Cardiovasc Interv 4:438-46. 2011
  10. ncbi request reprint Role of lipoprotein-associated phospholipase A2 in leukocyte activation and inflammatory responses
    Yi Shi
    Department of Surgery, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Atherosclerosis 191:54-62. 2007

Collaborators

Detail Information

Publications66

  1. ncbi request reprint Angiotensin-receptor blockers: revival of the systemic prevention of restenosis?
    Robert L Wilensky
    Hospital of the University of Pennsylvania, 3400 Spruce St, 9 Gates, Philadelphia, PA 19104, USA
    Cardiovasc Drugs Ther 17:63-73. 2003
    ....
  2. doi request reprint Lipoprotein-associated phospholipase A(2) and atherosclerosis
    Robert L Wilensky
    Cardiovascular Division, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Curr Opin Lipidol 20:415-20. 2009
    ..However, only recently have data emerged demonstrating a role of Lp-PLA2 in development of advanced coronary artery disease. Indeed, Lp-PLA2 may be an important link between lipid homeostasis and the vascular inflammatory response...
  3. ncbi request reprint The molecular basis of vulnerable plaque: potential therapeutic role for immunomodulation
    Robert L Wilensky
    University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Curr Opin Cardiol 22:545-51. 2007
    ..Through recent studies the role of the immune system on development of atherosclerosis and approaches to modulate this response are being elucidated...
  4. ncbi request reprint Role of magnetic resonance and intravascular magnetic resonance in the detection of vulnerable plaques
    Robert L Wilensky
    Cardiovascular Division, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Am Coll Cardiol 47:C48-56. 2006
    ..The self-contained intravascular MRI probe appears to hold promise in the identification of high-risk coronary atherosclerotic lesions with increased superficial lipid content...
  5. pmc Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development
    Robert L Wilensky
    Hospital of the University of Pennsylvania, 3400 Spruce Street, 9 Gates, Philadelphia, Pennsylvania 19104, USA
    Nat Med 14:1059-66. 2008
    ....
  6. ncbi request reprint Relation of percutaneous coronary intervention of complex lesions to clinical outcomes (from the NHLBI Dynamic Registry)
    Robert L Wilensky
    Cardiovascular Division, University of Pennsylvania, Philadelphia 19104, USA
    Am J Cardiol 90:216-21. 2002
    ..An increased in-hospital adverse clinical event rate was independently noted for thrombotic, bifurcation, and calcified lesions, and bifurcation lesions had worse long-term event rates...
  7. doi request reprint Site-specific atherogenic gene expression correlates with subsequent variable lesion development in coronary and peripheral vasculature
    Emile R Mohler
    University of Pennsylvania, Philadelphia, PA 19104, USA
    Arterioscler Thromb Vasc Biol 28:850-5. 2008
    ..We hypothesized that genes in the vasculature related to cholesterol metabolism, inflammation, and insulin signaling pathways are differentially regulated in a site-specific and time-dependent manner...
  8. doi request reprint Diabetes reduces bone marrow and circulating porcine endothelial progenitor cells, an effect ameliorated by atorvastatin and independent of cholesterol
    Emile R Mohler
    Department of Medicine, Cardiovascular Division, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Cytometry A 75:75-82. 2009
    ..These data suggest a model wherein accelerated atherosclerosis seen with DM may, in part, result from reduction in EPCs which may be ameliorated by treatment with a statin...
  9. doi request reprint Vascular responses to drug-eluting and bare metal stents in diabetic/hypercholesterolemic and nonatherosclerotic porcine coronary arteries
    Raul Llano
    Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104, USA
    Circ Cardiovasc Interv 4:438-46. 2011
    ....
  10. ncbi request reprint Role of lipoprotein-associated phospholipase A2 in leukocyte activation and inflammatory responses
    Yi Shi
    Department of Surgery, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Atherosclerosis 191:54-62. 2007
    ..To explore the biologic role of Lp-PLA2 in atherosclerosis, we examined its expression and contribution to leukocyte activation under proatherogenic conditions...
  11. doi request reprint Subsequent development of fibroatheromas with inflamed fibrous caps can be predicted by intracoronary near infrared spectroscopy
    DHAVALKUMAR PATEL
    Cardiovascular Division, Hospital of the University of Pennsylvania and Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104, USA
    Arterioscler Thromb Vasc Biol 33:347-53. 2013
    ..To prospectively evaluate whether the development of fibroatheromas exhibiting features of potential instability can be detected and predicted by serial invasive imaging...
  12. pmc Akt pathway is hypoactivated by synergistic actions of diabetes mellitus and hypercholesterolemia resulting in advanced coronary artery disease
    Damir Hamamdzic
    Cardiovascular Division, Hospital of University of Pennsylvania and Cardiovascular Institute, University of Pennsylvania 19104, USA
    Am J Physiol Heart Circ Physiol 299:H699-706. 2010
    ..Our results revealed a synergistic effect of DM and HC in triggering abnormal Akt signaling, resulting in advanced atherosclerosis...
  13. ncbi request reprint Clinical progression of incidental, asymptomatic lesions discovered during culprit vessel coronary intervention
    Ruchira Glaser
    University of Pennsylvania, Philadelphia, PA 19104, USA
    Circulation 111:143-9. 2005
    ..Such lesions have been treated conservatively because of risk of restenosis but now are being considered for PCI to prevent plaque instability. However, the impact of incidental stenoses on future cardiac events remains unknown...
  14. ncbi request reprint Effect of gender on prognosis following percutaneous coronary intervention for stable angina pectoris and acute coronary syndromes
    Ruchira Glaser
    University of Pennsylvania, Philadelphia, USA
    Am J Cardiol 98:1446-50. 2006
    ..05, p = 0.5). In conclusion, women undergoing PCI for NSTACS have a higher risk of major adverse cardiac events than men or women undergoing PCI for stable angina...
  15. pmc Intracoronary delivery of mesenchymal stem cells at high flow rates after myocardial infarction improves distal coronary blood flow and decreases mortality in pigs
    Raul Llano
    Cardiovascular Division, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Catheter Cardiovasc Interv 73:251-7. 2009
    ..Evaluate the effects of pressure and duration of intracoronary (IC) infusion of mesenchymal stem cells (MSCs) on delivery efficiency and safety after myocardial infarction (MI)...
  16. pmc Hypercholesterolemia suppresses Kir channels in porcine bone marrow progenitor cells in vivo
    Emile R Mohler
    Department of Medicine, Cardiovascular Division, Section of Vascular Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Biochem Biophys Res Commun 358:317-24. 2007
    ..We further asses the hypercholesterolemia sensitivity of Kir channels in BM-SP cells, which may play a key role in hypercholesterolemia-mediated regulation of EPCs...
  17. pmc Bisphosphonate-mediated gene vector delivery from the metal surfaces of stents
    Ilia Fishbein
    Division of Cardiology, The Children s Hospital of Philadelphia, Department of Chemical, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 103:159-64. 2006
    ..68 +/- 0.27 and 3.4 +/- 0.35; Ad-iNOS vs. control, P < 0.01). It is concluded that effective gene vector delivery from metallic stent surfaces can be achieved by using this approach...
  18. ncbi request reprint Usefulness of noncoronary vascular disease in predicting adverse events in the year following percutaneous coronary intervention
    Srihari S Naidu
    Cardiovascular Division, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Am J Cardiol 95:575-80. 2005
    ..Because PCI is often performed before vascular surgery, these data may lend insight to the risk/benefit ratio of such an approach...
  19. ncbi request reprint A placebo controlled, dose-ranging, safety study of allogenic mesenchymal stem cells injected by endomyocardial delivery after an acute myocardial infarction
    Seyed M Hashemi
    Cardiovascular Division, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    Eur Heart J 29:251-9. 2008
    ..Although mesenchymal stem cells (MSCs) show promising signs in reducing myocardial infarct (MI) size, the safety of endomyocardial delivery and the most efficacious dose is unknown...
  20. ncbi request reprint Beta-cyclodextrin tetradecasulfate, a novel cyclic oligosaccharide, inhibits thrombus and neointimal formation after coronary vascular injury
    Nicolas F Meneveau
    Department of Medicine, University of Pennsylvania, USA
    Coron Artery Dis 13:189-97. 2002
    ..Beta-cyclodextrin tetradecasulfate (beta-CDT) has been shown to inhibit fibroblast growth factor activity and we hypothesized that beta-CDT would reduce intimal formation...
  21. pmc Comparison of bare-metal and drug-eluting stents in patients with chronic kidney disease (from the NHLBI Dynamic Registry)
    Sandy M Green
    Heart and Vascular Institute, University of Pittsburgh Medical Center, Pennsylvania, USA
    Am J Cardiol 108:1658-64. 2011
    ..In conclusion, presence of CKD predicted poor outcomes after PCI with high rates of mortality regardless of stent type. The effect of DES in decreasing repeat revascularization appeared to be attenuated in these patients...
  22. doi request reprint Comparison of invasive and noninvasive assessment of aortic stenosis severity in the elderly
    Zachary M Gertz
    Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    Circ Cardiovasc Interv 5:406-14. 2012
    ..Accurate assessment of AVA is crucial to determine which patients are appropriate candidates for aortic valve replacement...
  23. ncbi request reprint One-year clinical outcomes of protected and unprotected left main coronary artery stenting
    Michael P Kelley
    Hospital of the University of Pennsylvania, University Health System, 9 Gates, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Eur Heart J 24:1554-9. 2003
    ..To evaluate outcomes for left main coronary artery (LMCA) stenting and compare results between protected (left coronary grafted) and unprotected LMCA stenting in the current bare-metal stent era...
  24. ncbi request reprint FilterWire distal embolic protection device for vein graft stenting: initial single-center experience
    Daniel M Kolansky
    Division of Cardiovascular Medicine, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Clin Cardiol 28:556-60. 2005
    ..The FilterWire distal embolic protection device has recently been approved as an adjunct to SVG intervention. We report here our initial experience in a single center in 30 consecutive patients using this device in SVG stenting...
  25. ncbi request reprint Hypercholesterolemia suppresses inwardly rectifying K+ channels in aortic endothelium in vitro and in vivo
    Yun Fang
    Institute for Medicine and Engineering, Department of Pathology and Laboratory Medicine, University of Pennsylvania, USA
    Circ Res 98:1064-71. 2006
    ..Therefore, we suggest that suppression of Kir current is one of the important factors in hypercholesterolemia-induced endothelial dysfunction...
  26. doi request reprint Local drug delivery for treatment of coronary and peripheral artery disease
    Zachary M Gertz
    Cardiovascular Division, Hospital of the University of Pennsylvania, and Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA, USA
    Cardiovasc Ther 29:e54-66. 2011
    ..In this review, we discuss the development, the clinical use, and the effects of LDD from balloon and stent-based platforms in the treatment of restenosis and thrombus...
  27. ncbi request reprint Renal insufficiency is an independent predictor of mortality after percutaneous coronary intervention
    Srihari S Naidu
    Cardiovascular Division, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Am J Cardiol 92:1160-4. 2003
    ....
  28. ncbi request reprint Effect of atorvastatin on postcardiac transplant increase in low-density lipoprotein cholesterol reduces development of intimal hyperplasia and progression of endothelial dysfunction
    Vincent Y See
    Cardiovascular Division, Hospital of the University of Pennsylvania, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 4024, USA
    Am J Cardiol 92:11-5. 2003
    ....
  29. ncbi request reprint Duration of clopidogrel therapy after placement of drug-eluting intracoronary stent
    Sarah A Spinler
    Philadelphia College of Pharmacy, University of the Sciences in Philadelphia, PA 19104, USA
    Am J Health Syst Pharm 64:1432-4. 2007
  30. ncbi request reprint A novel ultrasound method for evaluation of collateral development in limb ischemia
    Emile R Mohler
    Department of Medicine, Cardiovascular Division, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Vasc Med 7:169-75. 2002
    ..This non-invasive method is useful to quantify blood flow, visualize angiogenesis and determine areas of persistent lower limb ischemia, and may have an important role in evaluating new approaches to modulate angiogenesis...
  31. ncbi request reprint Site specific gene delivery in the cardiovascular system
    Ilia Fishbein
    Cardiology Research Laboratories, Children s Hospital of Philadelphia, Abramson Research Center, PA 19104, USA
    J Control Release 109:37-48. 2005
    ..Our group has successfully investigated in animal studies localized gene therapy using an ion channel mutation to treat atrial arrhythmias...
  32. ncbi request reprint Gene delivery to pig coronary arteries from stents carrying antibody-tethered adenovirus
    Bruce D Klugherz
    The Division of Cardiology, Children s Hospital of Philadelphia, University of Pennsylvania Health System and Philadelphia Veterans Administration Medical Center, Philadelphia, PA 19104, USA
    Hum Gene Ther 13:443-54. 2002
    ..Gene delivery using stent-based anti-viral antibody tethering of vectors should be suitable for a wide array of single or multiple therapeutic gene strategies...
  33. pmc Recent developments with lipoprotein-associated phospholipase A2 inhibitors
    Ryan J Chauffe
    Pennsylvania Hospital, 1 Pine West, 800 Spruce Street, Philadelphia, PA 19107, USA
    Curr Atheroscler Rep 12:43-7. 2010
    ..This article reviews the most recent developments with Lp-PLA(2) inhibitors...
  34. ncbi request reprint Patient satisfaction is comparable to early discharge versus overnight observation after elective percutaneous coronary intervention
    Ruchira Glaser
    Cardiology Consultants, Pennsylvania, Division of Cardiovascular Medicine, Christiana Hospital, Newark, Delaware, USA
    J Invasive Cardiol 21:464-7. 2009
    ..S. cohorts. We sought to assess patient satisfaction, safety and cost of a strategy of selective early discharge in U.S. patients undergoing PCI via a femoral approach with contemporary adjunctive pharmacologic and hemostasis agents...
  35. ncbi request reprint Twenty-eight-day efficacy and phamacokinetics of the sirolimus-eluting stent
    Bruce D Klugherz
    Laboratory for Experimental Cardiology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
    Coron Artery Dis 13:183-8. 2002
    ....
  36. doi request reprint The anti-oxidative capacity of high-density lipoprotein is reduced in acute coronary syndrome but not in stable coronary artery disease
    Parin J Patel
    Division of Cardiovascular Medicine, Department of Medicine, Hospital of University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Am Coll Cardiol 58:2068-75. 2011
    ..This study examined an anti-inflammatory property of high-density lipoprotein (HDL) in subjects with acute coronary syndrome (ACS) and stable coronary artery disease (CAD) compared with control subjects...
  37. ncbi request reprint Electron-beam computerized tomography correlates with coronary angiogram in chronic kidney disease patients
    Janelle Robinson
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Am J Nephrol 27:247-52. 2007
    ..The aim of this study was to determine the correlation in CKD patients between CAC measured by EBCT and 50% stenosis determined by coronary angiography (CA), the gold standard to identify atherosclerotic lesions...
  38. ncbi request reprint Intravascular magnetic resonance imaging
    Victor A Ferrari
    University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Top Magn Reson Imaging 18:401-8. 2007
    ....
  39. doi request reprint Darapladib
    Quang T Bui
    University of Pennsylvania, Hospital of the University of Pennsylvania, Cardiovascular Institute, Cardiovascular Division, Philadelphia, PA 19104, USA
    Expert Opin Investig Drugs 19:161-8. 2010
    ..Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) seems to play a major role in the development of such high-risk lesions, in both the coronary and carotid arteries. Darapladib is a selective inhibitor of Lp-PLA(2)...
  40. pmc Niacin and biosynthesis of PGD₂by platelet COX-1 in mice and humans
    Wen Liang Song
    Institute for Translational Medicine and Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Clin Invest 122:1459-68. 2012
    ..Thus, PGD₂, like PGI₂, may function as a homeostatic response to thrombogenic and hypertensive stimuli and may have particular relevance as a constraint on platelets during niacin therapy...
  41. ncbi request reprint Minimally invasive resection of papillary fibroelastoma in a high-risk patient
    Richard W Kim
    Division of Cardiothoracic Surgery, Department of Surgery, University of Pennsylvania, PA 19104, USA
    J Cardiovasc Med (Hagerstown) 8:639-41. 2007
    ....
  42. pmc Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis
    Amit V Khera
    Cardiovascular Institute, University of Pennsylvania, Philadelphia, USA
    N Engl J Med 364:127-35. 2011
    ..We hypothesized that the capacity of HDL to accept cholesterol from macrophages would serve as a predictor of atherosclerotic burden...
  43. doi request reprint Atherosclerotic plaque development
    Quang T Bui
    Cardiovascular Division, Hospital of the University of Pennsylvania, 9 Gates, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Int J Biochem Cell Biol 41:2109-13. 2009
    ..The interplay of macrophages, T lymphocytes and mast cells play a central role in both the development but more importantly in the progression of coronary and carotid artery disease to high-risk phenotypes...
  44. ncbi request reprint Comparison of degree of platelet inhibition by abciximab versus tirofiban in patients with unstable angina pectoris and non-Q-wave myocardial infarction undergoing percutaneous coronary intervention
    Howard C Herrmann
    University of Pennsylvania Medical Center, Philadelphia 19104, USA
    Am J Cardiol 89:1293-7. 2002
  45. pmc Porcine models of accelerated coronary atherosclerosis: role of diabetes mellitus and hypercholesterolemia
    Damir Hamamdzic
    Cardiovascular Division, Hospital of the University of Pennsylvania and Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Diabetes Res 2013:761415. 2013
    ..All four models reliably represent features of human vascular disease. ..
  46. pmc Intracoronary delivery of bone-marrow-derived stem cells
    Quang T Bui
    Cardiovascular Division, Hospital of the University of Pennsylvania and Cardiovascular Institute, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Stem Cell Res Ther 1:29. 2010
    ..The aim of this review will be to discuss the potential therapeutic effects of myocardial stem cell and progenitor cell therapy delivered by an intracoronary route with special reference to treatment of infarcted myocardium...
  47. ncbi request reprint Drug-eluting stents in preclinical studies: recommended evaluation from a consensus group
    Robert S Schwartz
    Minnesota Cardiovascular Research Institute and Minneapolis Heart Institute Foundation Minneapolis, 55407, USA
    Circulation 106:1867-73. 2002
  48. ncbi request reprint Reduced vascular complications after percutaneous coronary interventions with a nonmechanical suture device: results from the randomized RACE study
    Timothy A Sanborn
    Evanston Northwestern Healthcare, Evanston, Illinois 60201, USA
    Catheter Cardiovasc Interv 61:327-32. 2004
    ..The incidence of major complications after PCI was reduced with the device...
  49. ncbi request reprint Preclinical evaluation of drug-eluting stents for peripheral applications: recommendations from an expert consensus group
    Robert S Schwartz
    Minneapolis Heart Institute Foundation, Minnesota Cardiovascular Research Institute, 920 E 28th St, Minneapolis, MN 55407, USA
    Circulation 110:2498-505. 2004
  50. ncbi request reprint Separate and combined effects of local and continuous intravenous administration of beta-cyclodextrin tetradecasulfate on intimal hyperplasia after angioplasty in porcine coronary arteries
    Nicolas F Meneveau
    Department of Medicine Cardiovascular Division of the University of Pennsylvania, 19104, USA
    J Cardiovasc Pharmacol Ther 8:53-60. 2003
    ..This study was designed to assess the separate and combined effects of local intramural delivery and intravenous administration of beta-cyclodextrin tetrade-casulfate on neointimal formation and arterial damage following angioplasty...
  51. ncbi request reprint Unrestricted use of drug-eluting stents compared with bare-metal stents in routine clinical practice: findings from the National Heart, Lung, and Blood Institute Dynamic Registry
    J Dawn Abbott
    Department of Cardiology, Rhode Island Hospital, Providence, Rhode Island, USA
    J Am Coll Cardiol 50:2029-36. 2007
    ..We investigated the effectiveness and safety of drug-eluting stents (DES) as used in routine clinical practice...
  52. ncbi request reprint Diagnosis of thin-cap fibroatheromas by a self-contained intravascular magnetic resonance imaging probe in ex vivo human aortas and in situ coronary arteries
    Jacob Schneiderman
    Department of Vascular Surgery and Gottesdiener Vascular Biology Laboratory, The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Am Coll Cardiol 45:1961-9. 2005
    ..We sought to correlate findings obtained from a self-contained magnetic resonance imaging (MRI) probe with plaque morphology of ex vivo human aortas and coronary arteries...
  53. ncbi request reprint A quantitative, randomized study evaluating three methods of mesenchymal stem cell delivery following myocardial infarction
    Toby Freyman
    Boston Scientific Corporation, Natick, MA, USA
    Eur Heart J 27:1114-22. 2006
    ..This study was designed to quantitatively compare MSC engraftment rates after intravenous (IV), intracoronary (IC), or endocardial (EC) delivery in a porcine myocardial infarction (MI) model...
  54. ncbi request reprint Rash with both clopidogrel and ticlopidine in two patients following percutaneous coronary intervention with drug-eluting stents
    Kathy Makkar
    Mercy Suburban Hospital, Norristown, PA, USA
    Ann Pharmacother 40:1204-7. 2006
    ..To describe 2 cases of rash that occurred following oral administration of both clopidogrel and ticlopidine and to review previously published case reports...
  55. pmc A comparison of bare-metal and drug-eluting stents for off-label indications
    Oscar C Marroquin
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, USA
    N Engl J Med 358:342-52. 2008
    ..Recent reports suggest that off-label use of drug-eluting stents is associated with an increased incidence of adverse events. Whether the use of bare-metal stents would yield different results is unknown...
  56. ncbi request reprint Comparison of the efficacy of direct coronary stenting with sirolimus-eluting stents versus stenting with predilation by intravascular ultrasound imaging (from the DIRECT trial)
    Atsushi Hirohata
    Center for Research in Cardiovascular Intervention, Stanford University, Stanford, California, USA
    Am J Cardiol 98:1464-7. 2006
    ..This strategy appears to be associated with less neointimal hyperplasia near the distal stent edge...
  57. ncbi request reprint Safety of sirolimus-eluting stenting and its effect on restenosis in patients with unstable angina pectoris (a SIRIUS substudy)
    Giora Weisz
    Columbia University Medical Center, and Cardiovascular Research Foundation, New York, New York, USA
    Am J Cardiol 99:1044-50. 2007
    ..Patients with unstable angina undergoing percutaneous coronary intervention who meet the entry criteria of the SIRIUS study should be preferentially treated with SESs...
  58. ncbi request reprint Drug-eluting stents are here--now what? Implications for clinical practice and health care costs
    John W Hirshfeld
    Cleve Clin J Med 71:825-8. 2004
  59. ncbi request reprint Outcome of percutaneous coronary intervention in unstable angina pectoris versus stable angina pectoris in two different time periods
    Srihari S Naidu
    The Cardiovascular Division, Weill Cornell Medical Center, New York, New York, USA
    Am J Cardiol 98:447-52. 2006
    ....
  60. ncbi request reprint Adenovirus-catheter compatibility increases gene expression after delivery to porcine myocardium
    Wendy A Naimark
    Boston Scientific Corporation, Natick, MA 01760, USA
    Hum Gene Ther 14:161-6. 2003
    ..In conclusion, this study highlights the importance of adenovirus-material compatibility in gene delivery to the myocardium. Efficiency was greater when using the catheter designed to enhance biocompatibility...
  61. ncbi request reprint Role of cardiac troponin T in the long-term risk stratification of patients undergoing percutaneous coronary intervention
    Jorge R Kizer
    Division of Cardiology, Department of Medicine and Public Health, Weill Medical College of Cornell University, New York, NY, USA
    Eur Heart J 24:1314-22. 2003
    ..To investigate the long-term prognostic significance of pre- and post-procedure troponin T (TnT) elevations in patients undergoing percutaneous coronary intervention (PCI)...
  62. ncbi request reprint Ethnic differences in the presentation, treatment strategy, and outcomes of percutaneous coronary intervention (a report from the National Heart, Lung, and Blood Institute Dynamic Registry)
    James Slater
    New York University Medical Center, New York, New York 1016 649, USA
    Am J Cardiol 92:773-8. 2003
    ....
  63. ncbi request reprint Fenoldopam mesylate for the prevention of contrast-induced nephropathy: a randomized controlled trial
    Gregg W Stone
    Department of Cardiology, Cardiovascular Research Foundation and Lenox Hill Heart and Vascular Institute, New York, NY 10022, USA
    JAMA 290:2284-91. 2003
    ....
  64. ncbi request reprint Completeness of revascularization for multivessel coronary artery disease and its effect on one-year outcome: a report from the NHLBI Dynamic Registry
    Vankeepuram S Srinivas
    Division of Cardiology, Montefiore Medical Center, New York, NY 10461, USA
    J Interv Cardiol 20:373-80. 2007
    ..In conclusion, despite the presence of more unfavorable characteristics, patients undergoing TR demonstrate 1-year outcomes equivalent to those having CR, supporting its continued use in selected patients...
  65. ncbi request reprint Volume-to-creatinine clearance ratio: a pharmacokinetically based risk factor for prediction of early creatinine increase after percutaneous coronary intervention
    Warren K Laskey
    Division of Cardiology, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131 0001, USA
    J Am Coll Cardiol 50:584-90. 2007
    ..This study sought to validate a pharmacokinetically derived measure of the risk of an early increase in serum creatinine after percutaneous coronary intervention (PCI)...
  66. ncbi request reprint Importance of the postdischarge interval in assessing major adverse clinical event rates following percutaneous coronary intervention
    Warren K Laskey
    Division of Cardiology, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131 0001, USA
    Am J Cardiol 95:1135-9. 2005
    ..Most postdischarge events derive from pathology related to the controlled vessel. A 30-day MACE rate may serve as a more comprehensive measurement of procedural outcome...