Research Topics
| HAROLD WIESENFELDSummaryAffiliation: University of Pittsburgh Country: USA Publications
Research Grants
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Detail Information
Publications
Subclinical pelvic inflammatory disease and infertilityHarold C Wiesenfeld
Departments of Obstetrics, Gynecology and Reproductive Sciences and Pathology, Magee Womens Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Obstet Gynecol 120:37-43. 2012..Subclinical PID is common in women with uncomplicated chlamydial or gonococcal cervicitis or with bacterial vaginosis. We assessed whether women with subclinical PID are at an increased risk for infertility...
The use of once-daily dosing of gentamicin in obstetrics and gynecologyH C Wiesenfeld
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburg School of Medicine Magee Womens Research Institute, PA, USA
Infect Dis Obstet Gynecol 6:155-9. 1998..In this symposium, we will describe the pharmacokinetics of gentamicin and review new information advocating the use of once-daily administration of gentamicin...
Knowledge about sexually transmitted diseases in women among primary care physiciansHarold C Wiesenfeld
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Sex Transm Dis 32:649-53. 2005..The objectives of this study were to determine the knowledge about the management of STDs among primary care physicians and to identify physician characteristics associated with possession of STD knowledge...- Comparison of acute and subclinical pelvic inflammatory diseaseHarold C Wiesenfeld
Department of Obstetrics, Gynecology, and Reproductive Sciences and Magee Womens Research Institute, University of Pittsburgh School of Medicine, PA 15213, USA
Sex Transm Dis 32:400-5. 2005..The objective of this study was to compare the demographic, clinical, and microbiologic findings in women with subclinical pelvic inflammatory disease (PID) and women with acute PID... - Bacterial vaginosis is a strong predictor of Neisseria gonorrhoeae and Chlamydia trachomatis infectionHarold C Wiesenfeld
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Magee Womens Research Institute, Pittsburgh, PA 15213, USA
Clin Infect Dis 36:663-8. 2003..These data support the importance of vaginal flora in the defense against STD acquisition... - Lower genital tract infection and endometritis: insight into subclinical pelvic inflammatory diseaseHarold C Wiesenfeld
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Magee Womens Research Institute, Pennsylvania 15213, USA
Obstet Gynecol 100:456-63. 2002..Subclinical PID is believed to be an important cause of tubal factor infertility... - Association between elevated neutrophil defensin levels and endometritisHarold C Wiesenfeld
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
J Infect Dis 186:792-7. 2002..Neutrophil defensins appear to participate in the host defense in ascending pelvic infection and the pathogenesis of PID... - Predictive value of the clinical diagnosis of lower genital tract infection in womenDaniel V Landers
Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, University of Pittsburgh and Magee Women s Research Institute, Pittsburgh, PA, USA
Am J Obstet Gynecol 190:1004-10. 2004..We hypothesized that diagnostic approaches to lower genital tract infections are inaccurate and proposed this study to evaluate typical approaches... - The associations between pelvic inflammatory disease, Trichomonas vaginalis infection, and positive herpes simplex virus type 2 serologyThomas L Cherpes
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Sex Transm Dis 33:747-52. 2006.... - Insight into the treatment of vulvar pain: a survey of cliniciansGlenn M Updike
Department of Obstetrics, Gynecology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Am J Obstet Gynecol 193:1404-9. 2005..The purpose of this investigation was to determine practice patterns among clinicians who frequently treat patients with vulvar pain syndromes... - Endometrial plasma cells: do they indicate subclinical pelvic inflammatory disease?Sharon L Achilles
School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Sex Transm Dis 32:185-8. 2005..Subclinical PID is diagnosed histologically after endometrial biopsy. In the literature, many different histologic criteria have been used to define subclinical PID... - High rate of severe fetal outcomes associated with maternal parvovirus b19 infection in pregnancyRichard H Beigi
Department of Obstetrics, Gynecology and Reproductive Sciences, Magee Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Infect Dis Obstet Gynecol 2008:524601. 2008..To augment the understanding of parvovirus B19 infection in pregnancy with respect to maternal characteristics and their corresponding fetal outcomes... - Exploring the relationship among weight, race, and sexual behaviors among girlsAletha Yvette Akers
Department of Obstetrics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Pediatrics 124:e913-20. 2009..The relationship between weight and sexual behavior among adolescents is poorly understood. We examined this relationship in a nationally representative sample of high school girls... - Symptomatic urinary tract infections after surgery for prolapse and/or incontinenceGary Sutkin
Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee Womens Hospital, University of Pittsburgh, Pittsburgh, PA, USA
Int Urogynecol J 21:955-61. 2010..The purpose of our study was to estimate the frequency and risk factors for symptomatic urinary tract infection (UTI) after surgery for stress urinary incontinence (SUI) and/or pelvic organ prolapse (POP)... - Pelvic inflammatory disease: new diagnostic criteria and treatmentRichard H Beigi
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Magee Women s Hospital, 300 Halket Street, Pittsburgh, PA 15213, USA
Obstet Gynecol Clin North Am 30:777-93. 2003..As we learn more about the frequency and importance of subclinical PID, the true burden of upper genital tract infection upon reproductive age women continues to be elucidated... - Quality of life utilities for pelvic inflammatory disease health statesKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Sex Transm Dis 35:307-11. 2008..Utilities for PID could have important implications on the cost-effectiveness of interventions to prevent and manage this disease... - Inflammation on liquid-based cervical cytology: can leukocytes be used to triage for Chlamydia trachomatis testing?Nicole M Donnellan
Department of Obstetrics, Gynecology and Reproductive Sciences, Magee Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Am J Obstet Gynecol 196:e33-5. 2007..The study was undertaken to investigate whether leukocytes on liquid-based cervical cytology can predict Chlamydia trachomatis infection... - Vaginal polymorphonuclear leukocytes and bacterial vaginosis as markers for histologic endometritis among women without symptoms of pelvic inflammatory diseaseMark H Yudin
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Magee-Womens Hospital, Pennsylvania, USA
Am J Obstet Gynecol 188:318-23. 2003..1%) for the diagnosis of upper genital tract infection. CONCLUSION: The presence of vaginal polymorphonuclear leukocytes has a high sensitivity and negative predictive value for the diagnosis of upper genital tract infection... - Does digital vaginal examination using lubricant have an impact on testing for Chlamydia trachomatis by polymerase chain reaction?Pablo Uribasterra
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine and Magee Womens Research Institute, Pittsburgh, Pennsylvania, USA
Sex Transm Dis 29:112-3. 2002 - Alcohol and drug use and related disorders: An underrecognized health issue among adolescents and young adults attending sexually transmitted disease clinicsRobert L Cook
Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Sex Transm Dis 33:565-70. 2006.... - Predictors of chronic pelvic pain in an urban population of women with symptoms and signs of pelvic inflammatory diseaseCatherine L Haggerty
University of Pittsburgh, Department of Epidemiology, Pittsburgh, Pennsylvania 15261, USA
Sex Transm Dis 32:293-9. 2005..69; 95% CI, 0.44-1.10). CONCLUSIONS: A range of demographic, clinical, historical, and behavioral factors predict CPP after PID... - Primary care physician attitudes regarding sexually transmitted diseasesMichael R Ashton
School of Medicine, Department of Medicine, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213, USA
Sex Transm Dis 29:246-51. 2002..Interventions that influence STD-related attitudes may improve STD-prevention practices by primary care physicians... - Risk factors for cervicitis among women with bacterial vaginosisJeanne M Marrazzo
Department of Medicine, University of Washington, Seattle 98104, and Department of Pediatrics, Children s Hospital of Pittsburgh, PA, USA
J Infect Dis 193:617-24. 2006..Cervicitis commonly occurs in women with bacterial vaginosis (BV), often without concomitant chlamydial or gonococcal infection. The risk factors for cervicitis have not been described... - Combined hormonal contraception may be protective against Neisseria gonorrhoeae infectionPriya R Gursahaney
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Sex Transm Dis 37:356-60. 2010..The purpose of this study is to determine the influence of hormonal contraception on gonococcal infection in women exposed to males with gonococcal urethritis... - Untreated asymptomatic group B streptococcal bacteriuria early in pregnancy and chorioamnionitis at deliveryBrenna L Anderson
Division of Reproductive Infectious Diseases and Immunology, Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee Womens Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Am J Obstet Gynecol 196:524.e1-5. 2007..The objective of the study was to determine the frequency of adverse pregnancy outcomes in women with untreated asymptomatic group B beta-hemolytic streptococcal (GBS) bacteriuria during pregnancy... - Cost-effectiveness of alternative outpatient pelvic inflammatory disease treatment strategiesKenneth J Smith
Section of Decision Sciences and Clinical Systems Modeling, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Sex Transm Dis 34:960-6. 2007..Effectiveness differences between outpatient pelvic inflammatory disease (PID) treatment regimens are uncertain, but significant differences in cost exist... - Antimicrobial prophylaxis for cesarean delivery before skin incisionStephanie M Owens
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Magee Womens Research Institute, 300 Halket Street, Pittsburgh, PA 15213, USA
Obstet Gynecol 114:573-9. 2009..To estimate the effect of a hospital-wide change in the timing of antimicrobial prophylaxis in cesarean deliveries on maternal and neonatal infections... - Antibiotic therapy for acute pelvic inflammatory disease: the 2006 Centers for Disease Control and Prevention sexually transmitted diseases treatment guidelinesCheryl K Walker
Department of Obstetrics and Gynecology, University of California at Davis, Sacramento, CA, USA
Clin Infect Dis 44:S111-22. 2007..Important contributions to the literature that impact the 2006 guidelines are described in this article... - Additional antibiotic use and preterm birth among bacteriuric and nonbacteriuric pregnant womenBrenna L Anderson
Department of Obstetrics and Gynecology, Brown University, Providence, Rhode Island 02905, USA
Int J Gynaecol Obstet 102:141-5. 2008..To determine the risk of preterm birth related to use of additional antibiotics... - A growing concern: inability to diagnose vulvovaginal infections correctlyHarold C Wiesenfeld
Obstet Gynecol 104:199. 2004 - Maintenance fluconazole therapy for recurrent vulvovaginal candidiasisJack D Sobel
Division of Infectious Diseases, Wayne State University School of Medicine, Detroit, USA
N Engl J Med 351:876-83. 2004..No safe and convenient regimen has proved to be effective for the management of recurrent vulvovaginal candidiasis... - Women's satisfaction with an intravaginal Lactobacillus capsule for the treatment of bacterial vaginosisJeanne M Marrazzo
Department of Medicine, University of Washington, Seattle, Washington, USA
J Womens Health (Larchmt) 15:1053-60. 2006..To assess women's satisfaction with a vaginal capsule containing human-derived, H(2)O(2)-producing Lactobacillus crispatus at completion of a randomized, placebo-controlled study for treatment of bacterial vaginosis (BV)... - Factors associated with absence of H2O2-producing Lactobacillus among women with bacterial vaginosisRichard H Beigi
Department of Obstetrics and Gynecology, MetroHealth Medical Center and Case Western Reserve University, Cleveland, Ohio 44109, USA
J Infect Dis 191:924-9. 2005..Women with bacterial vaginosis have different microbiological profiles. Our objective was to identify risk factors for an absence of H(2)O(2)-producing lactobacilli among women with bacterial vaginosis... - Effectiveness of two tinidazole regimens in treatment of bacterial vaginosis: a randomized controlled trialCharles H Livengood
Duke University Medical Center, Durham, NC 27710, USA
Obstet Gynecol 110:302-9. 2007..S. Food and Drug Administration (FDA)-recommended criteria to define cure... - Timing of prophylactic antibiotic administration in the uninfected laboring gravida: a randomized clinical trialHarold C Wiesenfeld
Am J Obstet Gynecol 195:876-7; author reply 877-8. 2006 - Suppressive antibacterial therapy with 0.75% metronidazole vaginal gel to prevent recurrent bacterial vaginosisJack D Sobel
Department of Medicine, Wayne State University School of Medicine, Detroit, MI, USA
Am J Obstet Gynecol 194:1283-9. 2006..02). CONCLUSION: Suppressive therapy with twice-weekly metronidazole gel achieves a significant reduction in the recurrence rate of bacterial vaginosis; however, secondary vaginal candidiasis is common...
Research Grants
- Prevention of Infertility in Women With Subclinical PIDHAROLD WIESENFELD; Fiscal Year: 2007..During this study, very real public health questions will be asked and answered which will affect the way that lower genital tract infections are routinely managed, potentially enhancing fertility among American women. ..