Research Topics
| E M WhyteSummaryAffiliation: University of Pittsburgh Country: USA Publications
| Collaborators
|
Detail Information
Publications
Preventing depression after strokeEllen M Whyte
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, USA
Int Rev Psychiatry 18:471-81. 2006..Then, we will discuss recent research supporting the prevention of depression after stroke and the likely positive effect successful prevention may have on non-psychiatric outcomes...
Influence of serotonin-transporter-linked promoter region polymorphism on platelet activation in geriatric depressionE M Whyte
Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
Am J Psychiatry 158:2074-6. 2001..Variations in the serotonin-transporter-linked promoter region (5-HTTLPR) polymorphism may influence the degree of activation. The authors examined the association among depression, platelet activation, and 5-HTTLPR genotype...
Cognitive and behavioral correlates of low vitamin B12 levels in elderly patients with progressive dementiaEllen M Whyte
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Am J Geriatr Psychiatry 10:321-7. 2002..In AD, the prevalence of low vitamin B12 serum levels is consistent with that found in community-dwelling elderly persons in general but is associated with greater overall cognitive impairment...
The relation of white matter hyperintensities to cognitive performance in the normal old: education mattersRobert D Nebes
University of Pittsburgh Medical Center, Pennsylvania, USA
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 13:326-40. 2006..This is consistent with recent concepts of cognitive reserve, but does raise a question as to the underlying source of the cognitive decrement found in the sort of well-educated elders typically used in cognitive-aging studies...
Impact of prior treatment exposure on response to antidepressant treatment in late lifeJames D Tew
Advanced Center for Interventions and Services Research in Late-Life Mood Disorders, Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
Am J Geriatr Psychiatry 14:957-65. 2006..Most TR and TI patients eventually respond, but TR patients may require more intensive and longer courses of treatment than TI and TN patients...
Onset of depression in elderly persons after hip fracture: implications for prevention and early intervention of late-life depressionEric J Lenze
Advanced Center for Interventions and Services Research and John A Hartford Center of Excellence in Geriatric Psychiatry, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
J Am Geriatr Soc 55:81-6. 2007..To identify predictors of onset of major depressive disorder (MDD) and of depressive symptoms in subjects who suffered a hip fracture...
Recovery from major depression in older adults receiving augmentation of antidepressant pharmacotherapyMary Amanda Dew
Department of Psychiatry, University of Pittsburgh School of Medicine and Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
Am J Psychiatry 164:892-9. 2007..The authors examined likelihood, speed, and predictors of recovery in older adults receiving augmentation pharmacotherapy after inadequate response to standardized treatment with paroxetine plus interpersonal psychotherapy...
Preventing depression in medical illness: a new lead?Charles F Reynolds
Advanced Center for Interventions and Services Research for Late Life Mood Disorders, University of Pittsburgh School of Medicine, 3811 O Hara St, Pittsburgh, PA 15213, USA
Arch Gen Psychiatry 64:884-5. 2007
Medical burden in late-life bipolar and major depressive disordersAriel G Gildengers
Intervention Research Center for Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, The Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA
Am J Geriatr Psychiatry 16:194-200. 2008..The authors compare medical burden in elderly patients with bipolar disorder with that in those with major depressive disorder...
Depression in late-life: shifting the paradigm from treatment to preventionEllen M Whyte
University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Int J Geriatr Psychiatry 21:746-51. 2006....
CYP2D6 genotype and venlafaxine-XR concentrations in depressed elderlyEllen M Whyte
Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh School of Medicine, USA
Int J Geriatr Psychiatry 21:542-9. 2006....
Post stroke depression: epidemiology, pathophysiology, and biological treatmentEllen M Whyte
Department of Psychiatry, University of Pittsburgh, Pennsylvania 15213, USA
Biol Psychiatry 52:253-64. 2002..The authors conclude that the available evidence supports poststroke depression as being multifactorial in origin and consistent with the biopsychosocial model of mental illness...
Depression after stroke: a prospective epidemiological studyEllen M Whyte
Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
J Am Geriatr Soc 52:774-8. 2004....
Time course of response to antidepressants in late-life major depression: therapeutic implicationsEllen M Whyte
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Drugs Aging 21:531-54. 2004..Better understanding of factors related to such differences may suggest new intervention strategies to accelerate response...
The nature and determinants of neuropsychological functioning in late-life depressionMeryl A Butters
Department of Psychiatry, University of Pittsburgh Medical Center, PA, USA
Arch Gen Psychiatry 61:587-95. 2004..Further studies of neuropsychological functioning in remitted LLD patients are needed to parse episode-related and persistent factors and to relate them to underlying neural dysfunction...
Geriatric depression treatment in nonresponders to selective serotonin reuptake inhibitorsEllen M Whyte
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
J Clin Psychiatry 65:1634-41. 2004....
Differential cortical atrophy in subgroups of mild cognitive impairmentSandra Bell-McGinty
Department of Psychiatry, University of Pittsburgh Medical Center, PA, USA
Arch Neurol 62:1393-7. 2005..These data also suggest that these structural abnormalities precede the development of Alzheimer disease...
Maintenance treatment of major depression in old ageCharles F Reynolds
Advanced Center for Intervention and Services Research for Late Life Mood Disorders, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213, USA
N Engl J Med 354:1130-8. 2006..Elderly patients with major depression, including those having a first episode, are at high risk for recurrence of depression, disability, and death...
Empirically derived decision trees for the treatment of late-life depressionCarmen Andreescu
Advanced Center in Intervention and Services Research for Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, USA
Am J Psychiatry 165:855-62. 2008..The aim of this analysis was to develop a clinically useful algorithm that would allow clinicians to predict which patients will likely respond to treatment and thereby guide clinical decision making...
Persisting low use of antipsychotics in the treatment of major depressive disorder with psychotic featuresCarmen Andreescu
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
J Clin Psychiatry 68:194-200. 2007..We assessed the extent to which the pharmacotherapy received by patients with MD-Psy under usual care conforms to these recommendations...
Rescue pharmacotherapy with duloxetine for selective serotonin reuptake inhibitor nonresponders in late-life depression: outcome and tolerabilityJordan F Karp
Western Psychiatric Institute and Clinic, Advanced Center for Interventions and Services Research for Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
J Clin Psychiatry 69:457-63. 2008....
Missed diagnosis of psychotic depression at 4 academic medical centersAnthony J Rothschild
Department of Psychiatry, University of Massachusetts Medical School, and UMass Memorial Healthcare, Worcester, MA 01605, USA
J Clin Psychiatry 69:1293-6. 2008..Major depressive disorder with psychotic features (psychotic depression), though occurring relatively frequently in the general population, is a commonly missed psychiatric diagnosis...
