M A Whooley

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Association between depressive symptoms and mortality in older women. Study of Osteoporotic Fractures Research Group
    M A Whooley
    General Internal Medicine Section, San Francisco Department of Veterans Affairs Medical Center, University of California 94121, USA
    Arch Intern Med 158:2129-35. 1998
  2. ncbi Depression, falls, and risk of fracture in older women. Study of Osteoporotic Fractures Research Group
    M A Whooley
    San Francisco Department of Veterans Affairs Medical Center and the Department of Medicine, University of California 94121, USA
    Arch Intern Med 159:484-90. 1999
  3. ncbi Randomized trial of case-finding for depression in elderly primary care patients
    M A Whooley
    Section of General Internal Medicine, Department of Veterans Affairs Medical Center, San Francisco, California 94121, USA
    J Gen Intern Med 15:293-300. 2000
  4. ncbi Postmenopausal estrogen therapy and depressive symptoms in older women
    M A Whooley
    Section of General Internal Medicine, San Francisco Department of Veterans Affairs Medical Center, Departments of Medicine and Epidemiology and Biostatistics, University of California, San Francisco, California, USA
    J Gen Intern Med 15:535-41. 2000
  5. ncbi Depressive symptoms, unemployment, and loss of income: The CARDIA Study
    Mary A Whooley
    Department of Veterans Affairs Medical Center, 4150 Clement St Mail Stop 111A1, San Francisco, CA 94121
    Arch Intern Med 162:2614-20. 2002
  6. ncbi Religious involvement and cigarette smoking in young adults: the CARDIA study (Coronary Artery Risk Development in Young Adults)study (
    Mary A Whooley
    Department of Veterans Affairs Medical Center and Department of Medicine, University of California, San Fancisco, 94121, USA
    Arch Intern Med 162:1604-10. 2002
  7. ncbi Depressive symptoms and bone mineral density in older men
    Mary A Whooley
    San Francisco Department of Veterans Affairs Medical Center, 4150 Clement Street 111A1, San Francisco, CA 94121, USA
    J Geriatr Psychiatry Neurol 17:88-92. 2004
  8. ncbi Self-efficacy as a marker of cardiac function and predictor of heart failure hospitalization and mortality in patients with stable coronary heart disease: findings from the Heart and Soul Study
    Urmimala Sarkar
    Department of Medicine, Division of General Internal Medicine, University of California, San Francisco, Box 1732, San Francisco, CA 94143 1732, USA
    Health Psychol 28:166-73. 2009
  9. ncbi Pulmonary regurgitation end-diastolic gradient is a Doppler marker of cardiac status: data from the Heart and Soul Study
    Bryan Ristow
    California Pacific Medical Center, San Francisco, California 94115, USA
    J Am Soc Echocardiogr 18:885-91. 2005
  10. ncbi Depressive symptoms and health-related quality of life: the Heart and Soul Study
    Bernice Ruo
    Section of General Internal Medicine, Veterans Affairs Medical Center, San Francisco 94121, USA
    JAMA 290:215-21. 2003

Detail Information

Publications87

  1. ncbi Association between depressive symptoms and mortality in older women. Study of Osteoporotic Fractures Research Group
    M A Whooley
    General Internal Medicine Section, San Francisco Department of Veterans Affairs Medical Center, University of California 94121, USA
    Arch Intern Med 158:2129-35. 1998
    ..Major depression is associated with increased mortality, but it is not known whether patients who report depressive symptoms have greater mortality...
  2. ncbi Depression, falls, and risk of fracture in older women. Study of Osteoporotic Fractures Research Group
    M A Whooley
    San Francisco Department of Veterans Affairs Medical Center and the Department of Medicine, University of California 94121, USA
    Arch Intern Med 159:484-90. 1999
    ..Previous studies have suggested that depression is associated with falls and with low bone density, but it is not known whether depression leads to an increased risk of fracture...
  3. ncbi Randomized trial of case-finding for depression in elderly primary care patients
    M A Whooley
    Section of General Internal Medicine, Department of Veterans Affairs Medical Center, San Francisco, California 94121, USA
    J Gen Intern Med 15:293-300. 2000
    ....
  4. ncbi Postmenopausal estrogen therapy and depressive symptoms in older women
    M A Whooley
    Section of General Internal Medicine, San Francisco Department of Veterans Affairs Medical Center, Departments of Medicine and Epidemiology and Biostatistics, University of California, San Francisco, California, USA
    J Gen Intern Med 15:535-41. 2000
    ..Evidence regarding the effect of postmenopausal estrogen therapy on mood is limited...
  5. ncbi Depressive symptoms, unemployment, and loss of income: The CARDIA Study
    Mary A Whooley
    Department of Veterans Affairs Medical Center, 4150 Clement St Mail Stop 111A1, San Francisco, CA 94121
    Arch Intern Med 162:2614-20. 2002
    ..Previous studies have suggested an association between depression and low socioeconomic status, but few have empirically examined the effect of depressive symptoms on income and employment over time...
  6. ncbi Religious involvement and cigarette smoking in young adults: the CARDIA study (Coronary Artery Risk Development in Young Adults)study (
    Mary A Whooley
    Department of Veterans Affairs Medical Center and Department of Medicine, University of California, San Fancisco, 94121, USA
    Arch Intern Med 162:1604-10. 2002
    ..We sought to determine whether frequent attendance at religious services is associated with less smoking among young adults...
  7. ncbi Depressive symptoms and bone mineral density in older men
    Mary A Whooley
    San Francisco Department of Veterans Affairs Medical Center, 4150 Clement Street 111A1, San Francisco, CA 94121, USA
    J Geriatr Psychiatry Neurol 17:88-92. 2004
    ..These findings suggest that depressive symptoms are not associated with BMD in community-dwelling, older men...
  8. ncbi Self-efficacy as a marker of cardiac function and predictor of heart failure hospitalization and mortality in patients with stable coronary heart disease: findings from the Heart and Soul Study
    Urmimala Sarkar
    Department of Medicine, Division of General Internal Medicine, University of California, San Francisco, Box 1732, San Francisco, CA 94143 1732, USA
    Health Psychol 28:166-73. 2009
    ..The authors sought to evaluate the association of self-efficacy with objective measures of cardiac function, subsequent hospitalization for heart failure (HF), and all-cause mortality...
  9. ncbi Pulmonary regurgitation end-diastolic gradient is a Doppler marker of cardiac status: data from the Heart and Soul Study
    Bryan Ristow
    California Pacific Medical Center, San Francisco, California 94115, USA
    J Am Soc Echocardiogr 18:885-91. 2005
    ..Echocardiograms routinely sample pulmonary regurgitation signals from which it is possible to measure end diastolic gradients; these correlate with pulmonary artery diastolic pressures...
  10. ncbi Depressive symptoms and health-related quality of life: the Heart and Soul Study
    Bernice Ruo
    Section of General Internal Medicine, Veterans Affairs Medical Center, San Francisco 94121, USA
    JAMA 290:215-21. 2003
    ..Conversely, 2 traditional measures of cardiac function-ejection fraction and ischemia-are not. Efforts to improve health status should include assessment and treatment of depressive symptoms...
  11. ncbi Association of cystatin C and estimated GFR with inflammatory biomarkers: the Heart and Soul Study
    David Singh
    Department of Medicine, University of California, San Francisco, CA 94121, USA
    Nephrol Dial Transplant 22:1087-92. 2007
    ..In this study, we compared the relative strengths of association of cystatin C and estimated glomerular filtration rate (eGFR) with inflammatory biomarkers...
  12. ncbi Development of an echocardiographic risk-stratification index to predict heart failure in patients with stable coronary artery disease: the Heart and Soul study
    Steven M Stevens
    Department of Medicine, Division of Cardiology, University of California, San Francisco, California, USA
    JACC Cardiovasc Imaging 2:11-20. 2009
    ..We sought to determine which transthoracic echocardiographic (TTE) measurements most strongly predict heart failure (HF) and to develop an index for risk stratification in outpatients with coronary artery disease (CAD)...
  13. ncbi Depression, stress, and quality of life in persons with chronic kidney disease: the Heart and Soul Study
    Michelle C Odden
    Section of General Internal Medicine, San Francisco VA Medical Center, San Francisco, CA 94121, USA
    Nephron Clin Pract 103:c1-7. 2006
    ..These findings suggest that self- assessed overall health may decline at earlier stages of renal dysfunction than mental health outcomes or QOL...
  14. ncbi C-reactive protein and ischemia in users and nonusers of beta-blockers and statins: data from the Heart and Soul Study
    Mary S Beattie
    Department of Medicine, University of California, San Francisco, USA
    Circulation 107:245-50. 2003
    ..CONCLUSION: Elevated CRP levels are associated with inducible ischemia in patients with stable coronary disease, particularly among those not treated with beta-blockers or statins...
  15. ncbi Relation between depressive symptoms and treadmill exercise capacity in the Heart and Soul Study
    Bernice Ruo
    Section of General Internal Medicine, VA Medical Center, and Department of Medicine, University of California, San Francisco, USA
    Am J Cardiol 94:96-9. 2004
    ..8, 95% confidence interval 1.1 to 2.7, p = 0.01). Depressive symptoms should be considered in the differential diagnosis of poor exercise capacity...
  16. ncbi Adiponectin and inducible ischemia in patients with stable coronary heart disease: data from the Heart and Soul study
    Mary H Zhang
    University of California, San Francisco, CA 94121, USA
    Atherosclerosis 205:233-8. 2009
    ..We sought to determine whether higher adiponectin levels are associated with exercise-induced ischemia in patients with stable CHD...
  17. ncbi Association of anemia with diastolic dysfunction among patients with coronary artery disease in the Heart and Soul Study
    Deepu Nair
    Department of Department of Medicine, University of California, San Francisco, California, USA
    Am J Cardiol 95:332-6. 2005
    ..6, 95% CI 0.6 to 4.6) were not significantly associated with LVH. We found anemia to be strongly associated with diastolic dysfunction but not with LVH in this community-based sample of outpatients who had established coronary disease...
  18. ncbi Prognostic value of left ventricular end-systolic volume index as a predictor of heart failure hospitalization in stable coronary artery disease: data from the Heart and Soul Study
    David D McManus
    Division of Cardiology, Department of Medicine, University of California, San Francisco, California 94143, USA
    J Am Soc Echocardiogr 22:190-7. 2009
    ..The prognostic value of ESVI and its merit relative to other markers of LV remodeling in patients with coronary heart disease are unknown...
  19. ncbi N-terminal pro-B-type natriuretic peptide as a diagnostic test for ventricular dysfunction in patients with coronary disease: data from the heart and soul study
    David C M Corteville
    Department of Medicine, University of California, San Francisco, CA, USA
    Arch Intern Med 167:483-9. 2007
    ..Whether NT-proBNP can be used to detect ventricular dysfunction in patients with stable coronary heart disease (CHD) and no history of heart failure is unknown...
  20. ncbi Elevated pulmonary artery pressure by Doppler echocardiography predicts hospitalization for heart failure and mortality in ambulatory stable coronary artery disease: the Heart and Soul Study
    Bryan Ristow
    Department of Medicine, Division of Cardiology, University of California, San Francisco, California, USA
    J Am Coll Cardiol 49:43-9. 2007
    ..We compared the predictive ability of tricuspid regurgitation (TR) and end-diastolic pulmonary regurgitation (EDPR) gradients in outpatients with coronary artery disease...
  21. ncbi Kidney function and systolic blood pressure new insights from cystatin C: data from the Heart and Soul Study
    Carmen A Peralta
    General Internal Medicine Section, San Francisco Veterans Affairs Medical Center, and Department of Medicine, University of California, San Francisco, San Francisco, California 94124, USA
    Am J Hypertens 19:939-46. 2006
    ..Whether kidney function in the normal range is associated with systolic BP (SBP), diastolic BP (DBP), and pulse pressure is unclear...
  22. ncbi Depression and cardiovascular disease: healing the broken-hearted
    Mary A Whooley
    Veterans Affairs Medical Center and University of California, San Francisco Medical Center, San Francisco, CA 94121, USA
    JAMA 295:2874-81. 2006
    ..This article evaluates the importance of major depression in patients with cardiovascular disease, and provides practical guidance for identifying and treating this disorder...
  23. ncbi Association of cystatin C with mortality, cardiovascular events, and incident heart failure among persons with coronary heart disease: data from the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, Box 0532, HSE 672, University of California at San Francisco, San Francisco, CA 94143 0532, USA
    Circulation 115:173-9. 2007
    ..Cystatin C is a novel and sensitive endogenous marker of kidney function. Whether cystatin C concentrations are associated with adverse events among ambulatory persons with CHD is unknown...
  24. ncbi Cystatin C, left ventricular hypertrophy, and diastolic dysfunction: data from the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, Box 0532, HSE 672, University of California, San Francisco, San Francisco, CA 94143-0532, USA
    J Card Fail 12:601-7. 2006
    ..83; 95% CI 0.75 to 4.46; P = .15). CONCLUSION: Higher cystatin C concentrations are strongly associated with left ventricular hypertrophy and diastolic dysfunction in outpatients with coronary artery disease and without heart failure...
  25. ncbi C-reactive protein, diastolic dysfunction, and risk of heart failure in patients with coronary disease: Heart and Soul Study
    Eric S Williams
    San Francisco Veterans Affairs Medical Center and the University of California, San Francisco, CA, USA
    Eur J Heart Fail 10:63-9. 2008
    ..Whether the association of inflammation with incident HF is explained by worse baseline left ventricular dysfunction or by underlying CHD is unknown...
  26. ncbi N-terminal fragment of the prohormone brain-type natriuretic peptide (NT-proBNP), cardiovascular events, and mortality in patients with stable coronary heart disease
    Kirsten Bibbins-Domingo
    Department of Medicine, University of California, San Francisco, CA 94143, USA
    JAMA 297:169-76. 2007
    ..Identification of individuals at high risk for cardiovascular events is important for the optimal use of primary and secondary prevention measures...
  27. ncbi Red blood cell docosahexaenoic acid and eicosapentaenoic acid concentrations are positively associated with socioeconomic status in patients with established coronary artery disease: data from the Heart and Soul Study
    Beth E Cohen
    Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    J Nutr 138:1135-40. 2008
    ..Our results raise the possibility that (n-3) fatty acids may be an important mediating factor in the association between low SES and CVD...
  28. ncbi Biomarkers to predict recurrent cardiovascular disease: the Heart and Soul Study
    Michael G Shlipak
    Section of General Internal Medicine, San Francisco VA Medical Center, San Francisco, Calif, USA
    Am J Med 121:50-7. 2008
    ..The study purpose was to evaluate the ability of 6 biomarkers to improve the prediction of cardiovascular events among persons with established coronary artery disease...
  29. ncbi Association of African American race with elevated pulmonary artery diastolic pressure: data from the Heart and Soul Study
    Kiran K Khush
    Division of Cardiology, University of California, San Francisco, California 94143 0124, USA
    J Am Soc Echocardiogr 20:1307-13. 2007
    ..We hypothesized that African American race is associated with an elevated EDPR gradient that may partially predispose African Americans to heart failure...
  30. ncbi Interleukin-6 and atrial fibrillation in patients with coronary artery disease: data from the Heart and Soul Study
    Gregory M Marcus
    Electrophysiology Section, Division of Cardiology, University of California, San Francisco, CA 94143 1354, USA
    Am Heart J 155:303-9. 2008
    ..We therefore examined several biomarkers of inflammation and ultimately genotyped IL-6 polymorphisms in patients with AF in a cohort of subjects with known CAD...
  31. ncbi Usefulness of noninvasive estimate of pulmonary vascular resistance to predict mortality, heart failure, and adverse cardiovascular events in Patients With stable coronary artery disease (from the Heart and Soul Study)
    Ramin Farzaneh-Far
    Department of Medicine, University of California, San Francisco, California, USA
    Am J Cardiol 101:762-6. 2008
    ..3 to 4.7). In conclusion, a noninvasive estimate of PVR (TRV/VTI RVOT ratio) predicts mortality, heart failure hospitalization, and adverse cardiovascular events in patients with stable coronary artery disease...
  32. ncbi Self-efficacy and health status in patients with coronary heart disease: findings from the heart and soul study
    Urmimala Sarkar
    Department of Medicine, Division of General Internal Medicine, University of California, San Francisco, San Francisco, CA 94143 1211, USA
    Psychosom Med 69:306-12. 2007
    ..We hypothesized that lower self-efficacy would predict worse health status, independent of CHD severity and depression...
  33. ncbi Association of fetuin-A with mitral annular calcification and aortic stenosis among persons with coronary heart disease: data from the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, Box 0532, HSE 672, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    Circulation 115:2533-9. 2007
    ..Lower serum fetuin-A concentrations are associated with valvular calcification in persons with end-stage renal disease. Whether fetuin-A is associated with valvular calcification in other patient populations is unknown...
  34. ncbi Prognostic value of leukocyte telomere length in patients with stable coronary artery disease: data from the Heart and Soul Study
    Ramin Farzaneh-Far
    Department of Medicine, Box 0124, University of California San Francisco, CA 94143 0124, USA
    Arterioscler Thromb Vasc Biol 28:1379-84. 2008
    ..Telomere shortening has been proposed as a marker of biological aging. Whether leukocyte telomere length is associated with mortality among patients with stable coronary artery disease (CAD) is unknown...
  35. ncbi Depression and inflammation in patients with coronary heart disease: findings from the Heart and Soul Study
    Mary A Whooley
    Department of Veterans Affairs Medical Center, San Francisco, California University of California, San Francisco, CA 94121, USA
    Biol Psychiatry 62:314-20. 2007
    ..However, studies investigating the link between depression and inflammation in patients with established CHD have produced inconclusive results...
  36. ncbi A functional polymorphism in renalase (Glu37Asp) is associated with cardiac hypertrophy, dysfunction, and ischemia: data from the heart and soul study
    Ramin Farzaneh-Far
    Division of Cardiology, San Francisco General Hospital, San Francisco, California, United States of America
    PLoS ONE 5:e13496. 2010
    ..The association of this polymorphism with cardiac structure, function, and ischemia has not previously been reported...
  37. ncbi Fetuin-A and kidney function in persons with coronary artery disease--data from the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, Box 0532, HSE 672, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    Nephrol Dial Transplant 21:2144-51. 2006
    ..Whether fetuin-A concentrations are also lower in the setting of mild-to-moderate chronic kidney disease (CKD) is unknown...
  38. ncbi Psychological risk factors and the metabolic syndrome in patients with coronary heart disease: findings from the Heart and Soul Study
    Beth E Cohen
    General Internal Medicine, VA Medical Center, San Francisco, CA, United States Department of Medicine, University of California, San Francisco, CA, USA
    Psychiatry Res 175:133-7. 2010
    ..Further research is needed to determine whether addressing socioeconomic and behavioral factors in people with depression or high levels of anger or hostility could reduce the burden of the metabolic syndrome...
  39. ncbi Association between a serotonin transporter gene variant and hopelessness among men in the Heart and Soul Study
    Kirsten Neudoerffer Kangelaris
    Department of Medicine, Division of General Internal Medicine, University of California, San Francisco, San Francisco, CA, USA
    J Gen Intern Med 25:1030-7. 2010
    ....
  40. ncbi Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease
    Ramin Farzaneh-Far
    Division of Cardiology, Room 5G1, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA
    JAMA 303:250-7. 2010
    ..Increased dietary intake of marine omega-3 fatty acids is associated with prolonged survival in patients with coronary heart disease. However, the mechanisms underlying this protective effect are poorly understood...
  41. ncbi Additive effects of cognitive function and depressive symptoms on mortality in elderly community-living adults
    Kala M Mehta
    Division of Geriatrics, University of California at San Francisco, 4150 Clement Street, Box 181G, San Francisco, CA 94121, USA
    J Gerontol A Biol Sci Med Sci 58:M461-7. 2003
    ..Our aim was to examine whether the combination of varying levels of cognitive function and depressive symptoms affect the risk of mortality in community-living elderly adults...
  42. ncbi Telomere length trajectory and its determinants in persons with coronary artery disease: longitudinal findings from the heart and soul study
    Ramin Farzaneh-Far
    Division of Cardiology, San Francisco General Hospital, San Francisco, California, USA
    PLoS ONE 5:e8612. 2010
    ..We sought to investigate the longitudinal trajectory of telomere length, and to identify the independent predictors of telomere shortening, in persons with coronary artery disease...
  43. ncbi Posttraumatic stress disorder and health-related quality of life in patients with coronary heart disease: findings from the Heart and Soul Study
    Beth E Cohen
    Department of Veterans Affairs Medical Center, General Internal Medicine, University of California, San Francisco, CA 94121, USA
    Arch Gen Psychiatry 66:1214-20. 2009
    ..In addition to its tremendous mental health burden, PTSD has been associated with worse physical health status and an increased risk of cardiovascular disease...
  44. ncbi Is B-type natriuretic peptide a useful screening test for systolic or diastolic dysfunction in patients with coronary disease? Data from the Heart and Soul Study
    Kirsten Bibbins-Domingo
    Department of Medicine, University of California, San Francisco, USA
    Am J Med 116:509-16. 2004
    ..We examined the characteristics of a BNP test for identifying systolic and diastolic dysfunction in outpatients with stable coronary disease...
  45. ncbi Prevalence and prognostic significance of incidental cardiac troponin T elevation in ambulatory patients with stable coronary artery disease: data from the Heart and Soul study
    Bill P C Hsieh
    Division of Cardiology, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
    Am Heart J 158:673-9. 2009
    ..We sought to investigate the prevalence and prognostic value of cardiac troponin T (cTnT) elevation in a population with stable CAD...
  46. ncbi To screen or not to screen? Depression in patients with cardiovascular disease
    Mary A Whooley
    Veterans Affairs Medical Center and University of California, San Francisco, California, USA
    J Am Coll Cardiol 54:891-3. 2009
    ..Thus, patients with cardiovascular disease should receive routine screening for depression by primary care providers in the context of a collaborative care treatment program...
  47. ncbi Association between human fetuin-A and the metabolic syndrome: data from the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, University of California, San Francisco, CA 94143 0532, USA
    Circulation 113:1760-7. 2006
    ..We evaluated the association between human serum fetuin-A and the metabolic syndrome (MetS) in a cohort of persons with coronary artery disease...
  48. ncbi Depressive symptoms, health behaviors, and risk of cardiovascular events in patients with coronary heart disease
    Mary A Whooley
    VA Medical Center, San Francisco, California, USA
    JAMA 300:2379-88. 2008
    ..Depressive symptoms predict adverse cardiovascular outcomes in patients with coronary heart disease, but the mechanisms responsible for this association are unknown...
  49. ncbi Relation of low socioeconomic status to C-reactive protein in patients with coronary heart disease (from the heart and soul study)
    Lindsey A Lubbock
    Department of Veterans Affairs Medical Center, San Francisco, California, USA
    Am J Cardiol 96:1506-11. 2005
    ..In conclusion, low SES is associated with high CRP levels in patients who have CHD. This observation raises the possibility that inflammation may contribute to the adverse cardiovascular outcomes associated with low SES...
  50. ncbi Lack of association of chromosome 9p21.3 genotype with cardiovascular structure and function in persons with stable coronary artery disease: The Heart and Soul Study
    Ramin Farzaneh-Far
    Department of Medicine, University of California San Francisco, 94143 0124, United States
    Atherosclerosis 205:492-6. 2009
    ..We sought to compare cardiovascular structure and function in carriers and non-carriers of the risk haplotype in a cross-sectional study...
  51. ncbi Inverse association of erythrocyte n-3 fatty acid levels with inflammatory biomarkers in patients with stable coronary artery disease: The Heart and Soul Study
    Ramin Farzaneh-Far
    Department of Medicine, University of California San Francisco, 94143 0124, United States
    Atherosclerosis 205:538-43. 2009
    ..We sought to investigate the relationship between n-3 fatty acid levels in erythrocyte membranes and markers of systemic inflammation in 992 individuals with stable coronary artery disease...
  52. ncbi Depressive symptoms and perceived doctor-patient communication in the Heart and Soul study
    Yael Schenker
    Department of Medicine, University of California, San Francisco, Box 1364, San Francisco, CA 94143, USA
    J Gen Intern Med 24:550-6. 2009
    ..Little is known about the extent to which medical comorbidities, disease severity and depressive symptoms influence perceptions of doctor-patient communication in patients with chronic disease...
  53. ncbi Case-finding instruments for depression. Two questions are as good as many
    M A Whooley
    General Internal Medicine Section, San Francisco Department of Veterans Affairs Medical Center, CA 94121, USA
    J Gen Intern Med 12:439-45. 1997
    ..82 to 0.89. CONCLUSIONS: The two-question case-finding instrument is a useful measure for detecting depression in primary care. It has similar test characteristics to other case-finding instruments and is less time-consuming...
  54. ncbi Usefulness of diastolic dominant pulmonary vein flow to predict hospitalization for heart failure and mortality in ambulatory patients with coronary heart disease (from the Heart and Soul Study)
    Xiushui Ren
    Department of Cardiology, California Pacific Medical Center, San Francisco, California, USA
    Am J Cardiol 103:482-5. 2009
    ..004). In conclusion, diastolic dominant pulmonary vein flow pattern was a stand-alone predictor of adverse cardiac events, and its presence was associated with significantly higher rates of HF hospitalizations and cardiovascular death...
  55. ncbi Usefulness of left atrial volume index to predict heart failure hospitalization and mortality in ambulatory patients with coronary heart disease and comparison to left ventricular ejection fraction (from the Heart and Soul Study)
    Bryan Ristow
    California Pacific Medical Center, San Francisco, CA, USA
    Am J Cardiol 102:70-6. 2008
    ..4, p = 0.02), and LAVI >40 ml/m2 was predictive of mortality (OR 1.9, p = 0.005). In conclusion, LAVI had similar predictability as LVEF for HF hospitalization and mortality in ambulatory adults with coronary artery disease...
  56. ncbi Association of hepatitis C virus seropositivity with inflammatory markers and heart failure in persons with coronary heart disease: data from the Heart and Soul study
    Judith I Tsui
    Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine Boston Medical Center, Boston, MA 02118, USA
    J Card Fail 15:451-6. 2009
    ..How hepatitis C virus (HCV) affects coronary heart disease (CHD) risk factors and outcomes is largely unknown...
  57. ncbi Screening for depression in patients with coronary heart disease (data from the Heart and Soul Study)
    David McManus
    Department of Medicine, University of California, San Francisco, USA
    Am J Cardiol 96:1076-81. 2005
    ..A score > or =10 on the Patient Health Questionnaire-9 was 54% sensitive and 90% specific, with a positive likelihood ratio of 5.4. Thus, a cutpoint > or =10 was virtually diagnostic for depression...
  58. ncbi Depressive symptoms and 24-hour urinary norepinephrine excretion levels in patients with coronary disease: findings from the Heart and Soul Study
    Christian Otte
    Department of Psychiatry, University of California, San Francisco, CA 94121, USA
    Am J Psychiatry 162:2139-45. 2005
    ..Future longitudinal studies are needed to determine whether elevations in norepinephrine contribute to adverse cardiac outcomes in patients with depressive symptoms...
  59. ncbi Prognostic value of low-level cardiac troponin-I elevations in patients without definite acute coronary syndromes
    Michael X Pham
    General Internal Medicine Section, Veterans Affairs Medical Center, and the Division of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, Calif, USA
    Am Heart J 148:776-82. 2004
    ..However, their prognostic value in other clinical situations remains unclear...
  60. ncbi Association of chronic kidney disease and anemia with physical capacity: the heart and soul study
    Michelle C Odden
    Section of General Internal Medicine, San Francisco VA Medical Center, CA 94121, USA
    J Am Soc Nephrol 15:2908-15. 2004
    ..CKD and anemia are independently associated with physical limitation and reduced exercise capacity in outpatients with coronary disease, and these effects are additive. The broad impact of these disease conditions merits further study...
  61. ncbi Depression and 24-hour urinary cortisol in medical outpatients with coronary heart disease: The Heart and Soul Study
    Christian Otte
    Department of Psychiatry, University of California, Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Biol Psychiatry 56:241-7. 2004
    ..4, 95% CI 1.3-4.4, p <.01). In this cross-sectional analysis, elevated cortisol was not associated with worse cardiac function. CONCLUSIONS: In patients with CHD,depression is associated with elevated cortisol levels...
  62. ncbi B-type natriuretic peptide and ischemia in patients with stable coronary disease: data from the Heart and Soul study
    Kirsten Bibbins-Domingo
    Department of Medicine, University of California, San Francisco, USA
    Circulation 108:2987-92. 2003
    ..The observed association between BNP levels and ischemia may explain why tests for BNP are not specific for ventricular dysfunction among patients with coronary disease...
  63. ncbi Association between renal insufficiency and inducible ischemia in patients with coronary artery disease: the heart and soul study
    Joachim H Ix
    Department of Medicine, University of California, San Francisco, San Francisco, California 94121, USA
    J Am Soc Nephrol 14:3233-8. 2003
    ..The greater severity of atherosclerotic disease observed in patients with CRI may in part explain the association of CRI with increased cardiovascular risk among individuals with CAD...
  64. ncbi Prevalence and prognosis of asymptomatic left ventricular diastolic dysfunction in ambulatory patients with coronary heart disease
    Xiushui Ren
    Department of Cardiology, California Pacific Medical Center, University of California, San Francisco, USA
    Am J Cardiol 99:1643-7. 2007
    ..Patients with asymptomatic LV diastolic dysfunction may benefit from more aggressive therapy to prevent or delay the development of HF...
  65. ncbi Predicting heart failure hospitalization and mortality by quantitative echocardiography: is body surface area the indexing method of choice? The Heart and Soul Study
    Bryan Ristow
    California Pacific Medical Center, San Francisco, California 94115, USA
    J Am Soc Echocardiogr 23:406-13. 2010
    ..The American Society of Echocardiography recommends dividing measurements by body surface area (BSA), but others have advocated alternative indexing methods...
  66. ncbi Relation of self-reported angina pectoris to inducible myocardial ischemia in patients with known coronary artery disease: the Heart and Soul Study
    Anil K Gehi
    Department of Medicine, University of California-San Francisco, San Francisco, CA, USA
    Am J Cardiol 92:705-7. 2003
    ..We observed no association between self-reported angina pectoris and objective evidence of inducible ischemia...
  67. ncbi Left-ventricular power-to-mass ratio at peak exercise predicts mortality, heart failure, and cardiovascular events in patients with stable coronary artery disease: data from the Heart and Soul Study
    Ramin Farzaneh-Far
    Department of Medicine, University of California, CA 94143 0124, USA
    Cardiology 114:226-34. 2009
    ..We hypothesized that LVPMR at peak exercise provides prognostic information beyond established echocardiographic indices such as left-ventricular ejection fraction (LVEF) and left-ventricular mass index (LVMI)...
  68. ncbi Association of metabolic syndrome with exercise capacity and heart rate recovery in patients with coronary heart disease in the heart and soul study
    Christian Spies
    Section of Cardiology, Rush University Medical Center, Chicago, Illinois, USA
    Am J Cardiol 95:1175-9. 2005
    ..Decreased exercise capacity may contribute to the adverse outcomes associated with the metabolic syndrome...
  69. ncbi Quality-of-life and depressive symptoms in postmenopausal women after receiving hormone therapy: results from the Heart and Estrogen/Progestin Replacement Study (HERS) trial
    Mark A Hlatky
    Stanford University School of Medicine, HRP Redwood Bldg, Room 150, Stanford, CA 94305 5405, USA
    JAMA 287:591-7. 2002
    ..Postmenopausal hormone therapy is commonly used by women for disease prevention, but its effects on quality of life have not been well documented...
  70. ncbi Central nervous system-active medications and risk for falls in older women
    Kristine E Ensrud
    Department of Medicine, Veterans Affairs Medical Center, Minneapolis, Minnesota, USA
    J Am Geriatr Soc 50:1629-37. 2002
    ..To determine whether current use of central nervous system (CNS)-active medications, including benzodiazepines, antidepressants, anticonvulsants, and narcotics, increases the risk for subsequent falls...
  71. ncbi Central nervous system active medications and risk for fractures in older women
    Kristine E Ensrud
    Department of Medicine and Center for Chronic Disease Outcomes Research, VA Medical Center, Minneapolis, MN 55417, USA
    Arch Intern Med 163:949-57. 2003
    ..Use of central nervous system (CNS) active medications may increase the risk for fractures. Prior studies are limited by incomplete control of confounders...
  72. ncbi Blood pressure reactivity to psychological stress predicts hypertension in the CARDIA study
    Karen A Matthews
    University of Pittsburgh, 3811 O Hara St, Pittsburgh, PA, USA
    Circulation 110:74-8. 2004
    ..We tested whether BP changes during psychological stress predict incident hypertension in young adults...
  73. ncbi Depression and heart rate variability in patients with stable coronary heart disease: findings from the Heart and Soul Study
    Anil Gehi
    The Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai School of Medicine, New York, NY, USA
    Arch Gen Psychiatry 62:661-6. 2005
    ..These findings raise questions about the potential role of HRV in the association between depression and cardiovascular disease...
  74. ncbi Relation of anemia to low heart rate variability in patients with coronary heart disease (from the Heart and Soul study)
    Anil Gehi
    Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai School of Medicine, New York, New York, USA
    Am J Cardiol 95:1474-7. 2005
    ..Thus, anemia is associated with low HRV in ambulatory patients who have stable coronary heart disease. Low HRV could potentially mediate the association of anemia with increased cardiac risk...
  75. ncbi Differential association of cognitive and somatic depressive symptoms with heart rate variability in patients with stable coronary heart disease: findings from the Heart and Soul Study
    Peter De Jonge
    Department of Internal Medicine, University Medical Center Groningen, University of Groningen, The Netherlands
    Psychosom Med 69:735-9. 2007
    ....
  76. ncbi Association of a serotonin transporter polymorphism (5-HTTLPR) with depression, perceived stress, and norepinephrine in patients with coronary disease: the Heart and Soul Study
    Christian Otte
    Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Am J Psychiatry 164:1379-84. 2007
    ..Whether the short allele increases risk for depression associated with the stress of a chronic illness has not been established...
  77. ncbi Association between anaemia and N-terminal pro-B-type natriuretic peptide (NT-proBNP): findings from the Heart and Soul Study
    Arati S Desai
    Department of Medicine, Johns Hopkins University, United States
    Eur J Heart Fail 9:886-91. 2007
    ..Anaemia is associated with elevated levels of natriuretic peptides. Whether the association of anaemia with natriuretic peptides is independent of other cardiovascular risk factors is unclear...
  78. ncbi Depressive symptoms and rates of bone loss at the hip in older women
    Susan J Diem
    Department of Medicine, Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55415, USA
    J Am Geriatr Soc 55:824-31. 2007
    ..To ascertain whether depressive symptoms are associated with increased rates of bone loss at the hip...
  79. ncbi Acute myocardial infarction in patients with versus without aortic valve sclerosis and effect of statin therapy (from the Heart and Soul Study)
    Sanjiv J Shah
    Division of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois, USA
    Am J Cardiol 99:1128-33. 2007
    ..4-fold increased rate of subsequent MI. Statins may attenuate the increased risk of future MI in patients with aortic sclerosis...
  80. ncbi Association of cystatin C with poor exercise capacity and heart rate recovery: data from the heart and soul study
    David McManus
    Cardiology Division, University of Massachusetts, Worcester, MA, USA
    Am J Kidney Dis 49:365-72. 2007
    ..We hypothesized that serum cystatin C concentration would have a stronger more linear association with cardiovascular functional status than creatinine-based measures in outpatients with established coronary heart disease (CHD)...
  81. ncbi Inducible ischemia and the risk of recurrent cardiovascular events in outpatients with stable coronary heart disease: the heart and soul study
    Anil K Gehi
    Division of Cardiology, Emory University Hospital, 1364 Clifton Rd NE, Ste 424, Atlanta, GA 30322, USA
    Arch Intern Med 168:1423-8. 2008
    ..Our objective was to compare the prognosis of self-reported angina symptoms, inducible ischemia, or both in patients with stable CHD...
  82. ncbi Blood pressure reactivity to psychological stress and coronary calcification in the Coronary Artery Risk Development in Young Adults Study
    Karen A Matthews
    University of Pittsburgh, Pittsburgh, PA 15213, USA
    Hypertension 47:391-5. 2006
    ..Blood pressure reactivity may provide useful prognostic information about future risk beyond standard risk factors...
  83. ncbi Depression and medication adherence in outpatients with coronary heart disease: findings from the Heart and Soul Study
    Anil Gehi
    The Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai School of Medicine, New York, NY, USA
    Arch Intern Med 165:2508-13. 2005
    ..009 for not taking medications as prescribed). CONCLUSIONS: Depression is associated with medication nonadherence in outpatients with CHD. Medication nonadherence may contribute to adverse cardiovascular outcomes in depressed patients...
  84. ncbi Depression predicts mortality and hospitalization in patients with myocardial infarction complicated by heart failure
    John S Rumsfeld
    Section of Cardiology, Denver VA Medical Center, Denver, Colorado 80220, USA
    Am Heart J 150:961-7. 2005
    ..To evaluate whether depressive symptoms are independently predictive of mortality and hospitalization among patients with acute myocardial infarction (AMI) complicated by heart failure...
  85. ncbi Self-reported medication adherence and cardiovascular events in patients with stable coronary heart disease: the heart and soul study
    Anil K Gehi
    Emory University Hospital, 1364 Clifton Rd NE, Ste 414, Atlanta, GA 30322
    Arch Intern Med 167:1798-803. 2007
    ..Whether patient self-report can provide an accurate assessment of medication adherence in outpatients with stable coronary heart disease is unknown...
  86. ncbi Depression screening and patient outcomes in cardiovascular care: a systematic review
    Brett D Thombs
    Department of Psychiatry, McGill University, Montreal, Quebec, Canada
    JAMA 300:2161-71. 2008
    ..Several practice guidelines recommend that depression be evaluated and treated in patients with cardiovascular disease, but the potential benefits of this are unclear...
  87. ncbi Mind your heart
    Mary A Whooley
    Ann Intern Med 144:858-60. 2006