Colin D Whitmore

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Six orders of magnitude dynamic range in capillary electrophoresis with ultrasensitive laser-induced fluorescence detection
    Colin D Whitmore
    Department of Chemistry, University of Washington, Seattle, WA 98195 1700, USA
    Talanta 80:744-8. 2009
  2. doi request reprint Chemical cytometry: fluorescence-based single-cell analysis
    Daniella Cohen
    Department of Chemistry, University of Washington, Seattle, 98195, USA
    Annu Rev Anal Chem (Palo Alto Calif) 1:165-90. 2008
  3. pmc Monitoring the uptake of glycosphingolipids in Plasmodium falciparum-infected erythrocytes using both fluorescence microscopy and capillary electrophoresis with laser-induced fluorescence detection
    David C Essaka
    Department of Chemistry, University of Washington, Box 351700, Seattle, Washington 98195, USA
    Anal Chem 82:9955-8. 2010
  4. ncbi request reprint Yoctomole analysis of ganglioside metabolism in PC12 cellular homogenates
    Colin D Whitmore
    Department of Chemistry, University of Washington, Seattle, WA, USA
    Electrophoresis 28:3100-4. 2007
  5. pmc Interface of an array of five capillaries with an array of one-nanoliter wells for high-resolution electrophoretic analysis as an approach to high-throughput chemical cytometry
    Anna K Boardman
    Department of Chemistry, University of Washington, Seattle Washington 98195, USA
    Anal Chem 80:7631-4. 2008
  6. ncbi request reprint Instrumentation for medium-throughput two-dimensional capillary electrophoresis with laser-induced fluorescence detection
    Cuiru Zhu
    Department of Chemistry, University of Washington, Seattle, Washington 98195 1700, USA
    Anal Chem 79:765-8. 2007
  7. ncbi request reprint Metabolic cytometry. Glycosphingolipid metabolism in single cells
    Colin D Whitmore
    Department of Chemistry, University of Washington, Box 351700, Seattle, Washington 98195, USA
    Anal Chem 79:5139-42. 2007
  8. ncbi request reprint Chemical cytometry: the chemical analysis of single cells
    Emily H Turner
    Department of Chemistry, University of Washington, Seattle, WA 98195 1700, USA
    Anal Bioanal Chem 390:223-6. 2008
  9. pmc CE-MALDI interface based on inkjet technology
    Michael W Vannatta
    Department of Chemistry, University of Washington, Seattle, WA, USA
    Electrophoresis 30:4071-4. 2009

Collaborators

  • NORMAN DOVICHI
  • Niels H H Heegaard
  • Cuiru Zhu
  • Daniella Cohen
  • Emily H Turner
  • David C Essaka
  • Monica M Palcic
  • Ole Hindsgaul
  • Michael W Vannatta
  • Anna K Boardman
  • John White
  • Pradip Rathod
  • Mary E Lidstrom
  • Jane A Dickerson
  • David Gonzalez Gomez
  • Sarah C McQuaide
  • Haley R Pugsley
  • David G Gomez
  • James R Kraly
  • Megan R Jones
  • Xinya He
  • Wes Quigley
  • Anna Boardman
  • Michael Eggertson

Detail Information

Publications9

  1. pmc Six orders of magnitude dynamic range in capillary electrophoresis with ultrasensitive laser-induced fluorescence detection
    Colin D Whitmore
    Department of Chemistry, University of Washington, Seattle, WA 98195 1700, USA
    Talanta 80:744-8. 2009
    ..Mass detection limits were 150 yoctomoles injected onto the capillary...
  2. doi request reprint Chemical cytometry: fluorescence-based single-cell analysis
    Daniella Cohen
    Department of Chemistry, University of Washington, Seattle, 98195, USA
    Annu Rev Anal Chem (Palo Alto Calif) 1:165-90. 2008
    ..It is now possible to detect yoctomole amounts of many analytes in single cells...
  3. pmc Monitoring the uptake of glycosphingolipids in Plasmodium falciparum-infected erythrocytes using both fluorescence microscopy and capillary electrophoresis with laser-induced fluorescence detection
    David C Essaka
    Department of Chemistry, University of Washington, Box 351700, Seattle, Washington 98195, USA
    Anal Chem 82:9955-8. 2010
    ..The lysate from erythrocytes infected at 1% parasitemia generated a signal 20 standard deviations larger than uninfected erythrocytes, which suggests that relatively low infection levels can be studied with this technique...
  4. ncbi request reprint Yoctomole analysis of ganglioside metabolism in PC12 cellular homogenates
    Colin D Whitmore
    Department of Chemistry, University of Washington, Seattle, WA, USA
    Electrophoresis 28:3100-4. 2007
    ..Metabolite that preserves the fluorescent label can be detected at the yoctomole level, which should allow characterization of this metabolic pathway in single cells...
  5. pmc Interface of an array of five capillaries with an array of one-nanoliter wells for high-resolution electrophoretic analysis as an approach to high-throughput chemical cytometry
    Anna K Boardman
    Department of Chemistry, University of Washington, Seattle Washington 98195, USA
    Anal Chem 80:7631-4. 2008
    ..The number of cells found in each well was estimated visually under the microscope and was described by a Poisson distribution with mean of 0.98 cell/well. This system provides an approach to high-throughput chemical cytometry...
  6. ncbi request reprint Instrumentation for medium-throughput two-dimensional capillary electrophoresis with laser-induced fluorescence detection
    Cuiru Zhu
    Department of Chemistry, University of Washington, Seattle, Washington 98195 1700, USA
    Anal Chem 79:765-8. 2007
    ..3 +/- 0.7 transfers in the CSE dimension and 0.46 +/- 0.25 s in the MECC dimension. The standard deviation in spot position was 1.8 +/- 1.2 transfers in the CSE dimension and 0.88 +/- 0.55 s in the MECC dimension. Spot capacity was 300...
  7. ncbi request reprint Metabolic cytometry. Glycosphingolipid metabolism in single cells
    Colin D Whitmore
    Department of Chemistry, University of Washington, Box 351700, Seattle, Washington 98195, USA
    Anal Chem 79:5139-42. 2007
    ..The average cell took up roughly 2 amol (10(6) copies) of the labeled substrate. This method allows determination of cell-to-cell diversity and regulation of glycosphingolipid metabolism...
  8. ncbi request reprint Chemical cytometry: the chemical analysis of single cells
    Emily H Turner
    Department of Chemistry, University of Washington, Seattle, WA 98195 1700, USA
    Anal Bioanal Chem 390:223-6. 2008
  9. pmc CE-MALDI interface based on inkjet technology
    Michael W Vannatta
    Department of Chemistry, University of Washington, Seattle, WA, USA
    Electrophoresis 30:4071-4. 2009
    ..Detection limits were 500 amol for an ABI TOF-TOF instrument and 2 fmol for an ABI Q-TOF instrument. Over 70% coverage was obtained for the tryptic digest of alpha-lactalbumin in less than 2.5 min...