Luke J Whitesell

Summary

Affiliation: University of Arizona
Country: USA

Publications

  1. pmc The physical association of multiple molecular chaperone proteins with mutant p53 is altered by geldanamycin, an hsp90-binding agent
    L Whitesell
    Department of Pediatrics and Steele Memorial Children s Research Center, University of Arizona, Tucson 85724, USA
    Mol Cell Biol 18:1517-24. 1998
  2. ncbi request reprint Inhibition of oncogene expression using vector-generated RNA antisense
    L Whitesell
    Department of Pediatrics, University of Arizona, Tucson, Arizona 85724, USA
    Methods 18:296-303. 1999
  3. ncbi request reprint The stress response: implications for the clinical development of hsp90 inhibitors
    Luke Whitesell
    Steele Memorial Children s Research Center, University of Arizona, Tucson, AZ 85724, USA
    Curr Cancer Drug Targets 3:349-58. 2003

Collaborators

Detail Information

Publications3

  1. pmc The physical association of multiple molecular chaperone proteins with mutant p53 is altered by geldanamycin, an hsp90-binding agent
    L Whitesell
    Department of Pediatrics and Steele Memorial Children s Research Center, University of Arizona, Tucson 85724, USA
    Mol Cell Biol 18:1517-24. 1998
    ..GA did not, however, appear to restore wild-type transcriptional activating activity to mutant p53 proteins in either A1-5 cells or human breast cancer cell lines...
  2. ncbi request reprint Inhibition of oncogene expression using vector-generated RNA antisense
    L Whitesell
    Department of Pediatrics, University of Arizona, Tucson, Arizona 85724, USA
    Methods 18:296-303. 1999
    ..Lastly, using specific examples, the limitations and potential artifacts associated with antisense vector use in the study of tumorigenesis are discussed...
  3. ncbi request reprint The stress response: implications for the clinical development of hsp90 inhibitors
    Luke Whitesell
    Steele Memorial Children s Research Center, University of Arizona, Tucson, AZ 85724, USA
    Curr Cancer Drug Targets 3:349-58. 2003
    ..Lastly, stress response induction by Hsp90 inhibitors may have therapeutic benefits in non-neoplastic disorders such as heart disease, stroke and neurodegenerative diseases. These benefits are just beginning to be explored...