Stephanie White

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction
    Ikuko Teramitsu
    Interdepartmental Programs in Molecular, Cellular, and Integrative Physiology, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA
    J Neurosci 24:3152-63. 2004
  2. ncbi Singing mice, songbirds, and more: models for FOXP2 function and dysfunction in human speech and language
    Stephanie A White
    Department of Physiological Science, University of California, Los Angeles, California 90095, USA
    J Neurosci 26:10376-9. 2006
  3. ncbi Genes and vocal learning
    Stephanie A White
    Department of Physiological Science, University of California, Los Angeles, 90095, USA
    Brain Lang 115:21-8. 2010
  4. ncbi Social regulation of gonadotropin-releasing hormone
    Stephanie A White
    Program in Neuroscience, Stanford University, Stanford, CA 94305 2130, USA
    J Exp Biol 205:2567-81. 2002
  5. ncbi Language-related Cntnap2 gene is differentially expressed in sexually dimorphic song nuclei essential for vocal learning in songbirds
    S Carmen Panaitof
    Department of Physiological Science, University of California, Los Angeles, California 90095, USA
    J Comp Neurol 518:1995-2018. 2010
  6. ncbi FoxP2 regulation during undirected singing in adult songbirds
    Ikuko Teramitsu
    Interdepartmental Programs in Molecular, Cellular, and Integrative Physiology, University of California, Los Angeles, Los Angeles, California 90095, USA
    J Neurosci 26:7390-4. 2006
  7. ncbi Birdsong decreases protein levels of FoxP2, a molecule required for human speech
    Julie E Miller
    Department of Physiological Science, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    J Neurophysiol 100:2015-25. 2008
  8. ncbi Genetic components of vocal learning
    Constance Scharff
    Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany
    Ann N Y Acad Sci 1016:325-47. 2004
  9. ncbi A molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genes
    Kazuhiro Wada
    Department of Neurobiology and Duke Bioinformatics Shared Resource, Duke University Medical Center, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 103:15212-7. 2006
  10. ncbi The sleeping bird gets the song. Focus on: "HVC neural sleep activity increases with development and parallels nightly changes in song behavior"
    Julie E Miller
    J Neurophysiol 98:3-4. 2007

Research Grants

  1. Formation and Function of Circuitry for Vocal Learning
    Stephanie White; Fiscal Year: 2007
  2. Formation and Function of Circuitry for Vocal Learning
    Stephanie White; Fiscal Year: 2009

Collaborators

Detail Information

Publications11

  1. ncbi Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction
    Ikuko Teramitsu
    Interdepartmental Programs in Molecular, Cellular, and Integrative Physiology, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA
    J Neurosci 24:3152-63. 2004
    ..The specific colocalization of FoxP1 and FoxP2 found in several structures in the bird and human brain predicts that mutations in FOXP1 could also be related to speech disorders...
  2. ncbi Singing mice, songbirds, and more: models for FOXP2 function and dysfunction in human speech and language
    Stephanie A White
    Department of Physiological Science, University of California, Los Angeles, California 90095, USA
    J Neurosci 26:10376-9. 2006
    ..Below, we describe genetic through behavioral techniques used currently to investigate FoxP2 in birds, rodents, and humans for discovery of the neural bases of vocal learning and language...
  3. ncbi Genes and vocal learning
    Stephanie A White
    Department of Physiological Science, University of California, Los Angeles, 90095, USA
    Brain Lang 115:21-8. 2010
    ..The whole picture will only come together through comparative and integrative study into how the human language singularity evolved...
  4. ncbi Social regulation of gonadotropin-releasing hormone
    Stephanie A White
    Program in Neuroscience, Stanford University, Stanford, CA 94305 2130, USA
    J Exp Biol 205:2567-81. 2002
    ..Our data show that recognition of social signals by males alters stress levels, which may contribute to the alteration in GnRH gene expression in particular neurons essential for the animal to perform in its new social status...
  5. ncbi Language-related Cntnap2 gene is differentially expressed in sexually dimorphic song nuclei essential for vocal learning in songbirds
    S Carmen Panaitof
    Department of Physiological Science, University of California, Los Angeles, California 90095, USA
    J Comp Neurol 518:1995-2018. 2010
    ..Ongoing functional work will provide important insights into the relationship between Cntnap2 and vocal communication in songbirds and thereby clarify mechanisms at play in disorders of human cognition and language...
  6. ncbi FoxP2 regulation during undirected singing in adult songbirds
    Ikuko Teramitsu
    Interdepartmental Programs in Molecular, Cellular, and Integrative Physiology, University of California, Los Angeles, Los Angeles, California 90095, USA
    J Neurosci 26:7390-4. 2006
    ..Social context-dependent, acute changes in FoxP2 within the basal ganglia of adult songbirds also suggest, by analogy, that the core deficits of affected humans extend beyond development and beyond basic central motor control...
  7. ncbi Birdsong decreases protein levels of FoxP2, a molecule required for human speech
    Julie E Miller
    Department of Physiological Science, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    J Neurophysiol 100:2015-25. 2008
    ..Our data, together with recent reports on FoxP2's target genes, suggest that lowered FoxP2 levels may allow for expression of genes important for circuit modification and thus vocal variability...
  8. ncbi Genetic components of vocal learning
    Constance Scharff
    Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany
    Ann N Y Acad Sci 1016:325-47. 2004
    ..These latter regions also express FoxP2 in mammals and reptiles. We conclude that FoxP2 is important for the building and function of brain pathways including, but not limited to, those essential for learned vocal communication...
  9. ncbi A molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genes
    Kazuhiro Wada
    Department of Neurobiology and Duke Bioinformatics Shared Resource, Duke University Medical Center, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 103:15212-7. 2006
    ..This publicly accessible resource http://songbirdtranscriptome.net can now be used to study molecular neuroethological mechanisms of behavior...
  10. ncbi The sleeping bird gets the song. Focus on: "HVC neural sleep activity increases with development and parallels nightly changes in song behavior"
    Julie E Miller
    J Neurophysiol 98:3-4. 2007
  11. ncbi Motor learning: the FoxP2 puzzle piece
    Ikuko Teramitsu
    University College London, Wolfson Institute for Biomedical Research, Gower Street, London WC1E 6BT, UK
    Curr Biol 18:R335-7. 2008
    ..A recent study provides the first data on mice with this mutation, which exhibit deficits in motor-skill learning and abnormal properties of neural circuits that contribute to these skills...

Research Grants5

  1. Formation and Function of Circuitry for Vocal Learning
    Stephanie White; Fiscal Year: 2007
    ..Discovery of FoxP function in songbirds, the only experimentally tractable vocal learner, will additionally provide essential information regarding human disorders linked to FOXP mutations ..
  2. Formation and Function of Circuitry for Vocal Learning
    Stephanie White; Fiscal Year: 2009
    ..Discovery of FoxP function in songbirds, the only experimentally tractable vocal learner, will additionally provide essential information regarding human disorders linked to FOXP mutations ..