R James White

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. doi request reprint Pharmacokinetics of oral treprostinil sustained release tablets during chronic administration to patients with pulmonary arterial hypertension
    R James White
    Division of Pulmonary and Critical Care Medicine, University of Rochester, Rochester, NY 14623, USA
    J Cardiovasc Pharmacol 61:474-81. 2013
  2. doi request reprint Novel therapeutic approaches in pulmonary arterial hypertension: focus on tadalafil
    Y D Levin
    Department of Pulmonary and Critical Care Medicine, University of Rochester, Rochester, NY, USA
    Drugs Today (Barc) 47:145-56. 2011
  3. ncbi request reprint Tissue factor is induced in a rodent model of severe pulmonary hypertension characterized by neointimal lesions typical of human disease
    R James White
    Division of Pulmonary and Critical Care Medicine, Center for Cellular and Molecular Cardiology, Aab Institute for Biomedical Sciences, University of Rochester School of Medicine, Rochester, NY 14642, USA
    Chest 128:612S-613S. 2005
  4. ncbi request reprint Plexiform-like lesions and increased tissue factor expression in a rat model of severe pulmonary arterial hypertension
    R James White
    Division of Pulmonary and Critical Care Medicine, Univ of Rochester, 601 Elmwood Ave, Box 692, Rochester, NY, USA
    Am J Physiol Lung Cell Mol Physiol 293:L583-90. 2007
  5. doi request reprint Endothelin-1 induces pulmonary but not aortic smooth muscle cell migration by activating ERK1/2 MAP kinase
    David F Meoli
    Aab Cardiovascular Research Institute and Department of Pulmonary and Critical Care Medicine, University of Rochester, 400 Red Creek Drive, Suite 110, Rochester, NY 14623, USA
    Can J Physiol Pharmacol 88:830-9. 2010
  6. doi request reprint Sildenafil therapy is associated with improved hemodynamics in liver transplantation candidates with pulmonary arterial hypertension
    Michael S Gough
    Division of Pulmonary and Critical Care Medicine, University of Rochester Medical Center, Rochester, NY 14623, USA
    Liver Transpl 15:30-6. 2009
  7. pmc Thrombin induces fibronectin-specific migration of pulmonary microvascular endothelial cells: requirement of calcium/calmodulin-dependent protein kinase II
    David F Meoli
    Aab Cardiovascular Research Institute and Department of Pulmonary and Critical Care Medicine, University of Rochester, Rochester, New York, USA
    Am J Physiol Lung Cell Mol Physiol 297:L706-14. 2009
  8. doi request reprint Inhaled treprostinil sodium for the treatment of pulmonary arterial hypertension
    Matthew Ferrantino
    University of Rochester Medical Center, 400 Red Creek Dr, Suite 110, Rochester, NY 14623, USA
    Expert Opin Pharmacother 12:2583-93. 2011
  9. pmc G-protein-coupled receptor kinase interacting protein-1 is required for pulmonary vascular development
    Jinjiang Pang
    Aab Cardiovascular Research Institute and the Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Circulation 119:1524-32. 2009
  10. pmc Neonatal hyperoxia causes pulmonary vascular disease and shortens life span in aging mice
    Min Yee
    Department of Pediatrics, School of Medicine and Dentistry, The University of Rochester, Rochester, New York, USA
    Am J Pathol 178:2601-10. 2011

Collaborators

Detail Information

Publications10

  1. doi request reprint Pharmacokinetics of oral treprostinil sustained release tablets during chronic administration to patients with pulmonary arterial hypertension
    R James White
    Division of Pulmonary and Critical Care Medicine, University of Rochester, Rochester, NY 14623, USA
    J Cardiovasc Pharmacol 61:474-81. 2013
    ..We conclude that twice-daily oral treprostinil provides sustained and proportional treprostinil concentrations over a wide range of doses during chronic administration to PAH patients...
  2. doi request reprint Novel therapeutic approaches in pulmonary arterial hypertension: focus on tadalafil
    Y D Levin
    Department of Pulmonary and Critical Care Medicine, University of Rochester, Rochester, NY, USA
    Drugs Today (Barc) 47:145-56. 2011
    ....
  3. ncbi request reprint Tissue factor is induced in a rodent model of severe pulmonary hypertension characterized by neointimal lesions typical of human disease
    R James White
    Division of Pulmonary and Critical Care Medicine, Center for Cellular and Molecular Cardiology, Aab Institute for Biomedical Sciences, University of Rochester School of Medicine, Rochester, NY 14642, USA
    Chest 128:612S-613S. 2005
  4. ncbi request reprint Plexiform-like lesions and increased tissue factor expression in a rat model of severe pulmonary arterial hypertension
    R James White
    Division of Pulmonary and Critical Care Medicine, Univ of Rochester, 601 Elmwood Ave, Box 692, Rochester, NY, USA
    Am J Physiol Lung Cell Mol Physiol 293:L583-90. 2007
    ..Increased TF expression may contribute to the prothrombotic diathesis and vascular cell proliferation typical of human disease...
  5. doi request reprint Endothelin-1 induces pulmonary but not aortic smooth muscle cell migration by activating ERK1/2 MAP kinase
    David F Meoli
    Aab Cardiovascular Research Institute and Department of Pulmonary and Critical Care Medicine, University of Rochester, 400 Red Creek Drive, Suite 110, Rochester, NY 14623, USA
    Can J Physiol Pharmacol 88:830-9. 2010
    ..This finding may help explain the striking difference in the efficacy of endothelin receptor blockers for pulmonary hypertension as compared to that for systemic cardiovascular disease...
  6. doi request reprint Sildenafil therapy is associated with improved hemodynamics in liver transplantation candidates with pulmonary arterial hypertension
    Michael S Gough
    Division of Pulmonary and Critical Care Medicine, University of Rochester Medical Center, Rochester, NY 14623, USA
    Liver Transpl 15:30-6. 2009
    ..In conclusion, sildenafil was associated with improved hemodynamics in this small, uncontrolled cohort. A multicenter, prospective evaluation is warranted in this group uniformly excluded from phase III clinical trials...
  7. pmc Thrombin induces fibronectin-specific migration of pulmonary microvascular endothelial cells: requirement of calcium/calmodulin-dependent protein kinase II
    David F Meoli
    Aab Cardiovascular Research Institute and Department of Pulmonary and Critical Care Medicine, University of Rochester, Rochester, New York, USA
    Am J Physiol Lung Cell Mol Physiol 297:L706-14. 2009
    ....
  8. doi request reprint Inhaled treprostinil sodium for the treatment of pulmonary arterial hypertension
    Matthew Ferrantino
    University of Rochester Medical Center, 400 Red Creek Dr, Suite 110, Rochester, NY 14623, USA
    Expert Opin Pharmacother 12:2583-93. 2011
    ....
  9. pmc G-protein-coupled receptor kinase interacting protein-1 is required for pulmonary vascular development
    Jinjiang Pang
    Aab Cardiovascular Research Institute and the Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Circulation 119:1524-32. 2009
    ..However, there have been no in vivo studies of GIT1 function to date...
  10. pmc Neonatal hyperoxia causes pulmonary vascular disease and shortens life span in aging mice
    Min Yee
    Department of Pediatrics, School of Medicine and Dentistry, The University of Rochester, Rochester, New York, USA
    Am J Pathol 178:2601-10. 2011
    ..People exposed to hyperoxia as neonates may be at increased risk for pulmonary hypertension...