Research Topics
| R H WhiteSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Reversal of elevated international normalized ratios and bleeding with low-dose recombinant activated factor VII in patients receiving warfarinWilliam E Dager
Department of Pharmaceutical Services, University of California, Davis Medical Center, Sacramento, California 95817 2201, USA
Pharmacotherapy 26:1091-8. 2006..To assess the effectiveness of using low-dose recombinant activated factor VII (rFVIIa) to reverse the effects of warfarin in critically ill patients with major bleeding events...- Anticoagulation therapy after recent bleeding: is it ever safe?R H White
Division of General Medicine, Anticoagulation Service, Sacramento, CA 95817, USA
J Thromb Haemost 4:2365-6. 2006 - Recurrent venous thromboembolism after pregnancy-associated versus unprovoked thromboembolismRichard H White
Department of Internal Medicine, UC Davis, Sacramento, CA 95817, USA
Thromb Haemost 100:246-52. 2008..These findings should be considered when decisions are made about VTE prophylaxis in women with a history of pregnancy-associated VTE... 
Effects of race and ethnicity on the incidence of venous thromboembolismRichard H White
University of California, Davis, Sacramento, USA
Thromb Res 123:S11-7. 2009..Race/ethnicity should be considered an important factor in the risk-stratification of patients with suspected VTE or patients at some risk for developing VTE...- Low-molecular-weight heparins: are they all the same?Richard H White
Division of General Medicine, University of California Davis, 4150 V Street, Sacramento, CA 95817, USA
Br J Haematol 121:12-20. 2003 - The epidemiology of venous thromboembolismRichard H White
University of California, Davis, Sacramento, California, USA
Circulation 107:I4-8. 2003..Early mortality after VTE is strongly associated with presentation as PE, advanced age, cancer, and underlying cardiovascular disease... - Death due to recurrent thromboembolism among younger healthier individuals hospitalized for idiopathic pulmonary embolismRichard H White
Division of General Medicine, University of California, Davis, California, USA
Thromb Haemost 99:683-90. 2008..Among the patients who died of thromboembolism >28 days after the index PE, 28% had developed pulmonary hypertension... - Incidence of symptomatic venous thromboembolism after different elective or urgent surgical proceduresRichard H White
Division of General Medicine, University of California, Davis, California, USA
Thromb Haemost 90:446-55. 2003..Because of the high incidence of VTE diagnosed after hospital discharge, further studies of extended thromboprophylaxis appear warranted... - Effect of ethnicity and gender on the incidence of venous thromboembolism in a diverse population in California in 1996Richard H White
Division of General Medicine, University of California, Davis, California, USA
Thromb Haemost 93:298-305. 2005..Further research is needed to explain these observed differences among the different racial/ethnic groups... - Effect of age on the incidence of venous thromboembolism after major surgeryR H White
Division of General Medicine, University of California, Davis, USA
J Thromb Haemost 2:1327-33. 2004..We sought to quantify the effect of age on the risk of symptomatic VTE after a spectrum of surgical procedures... - Targeting patients for anticoagulant prophylaxis trials in patients with cancer: who is at highest risk?Richard H White
Department of Internal Medicine, University of California, Davis Sacramento, CA, USA
Thromb Res 120:S29-40. 2007..It is not clear which cancer patients are at highest risk for developing venous thromboembolism (VTE)... - Long-term incidence of death due to thromboembolic disease among patients with unprovoked pulmonary embolismRichard H White
Division of General Internal Medicine, University of California, Davis, Sacramento, California 95817, USA
Curr Opin Pulm Med 15:418-24. 2009..These findings will aid clinicians who must weigh the risk versus the benefits of long-term anticoagulant therapy... - How valid is the ICD-9-CM based AHRQ patient safety indicator for postoperative venous thromboembolism?Richard H White
Division of General Medicine, University of California, Davis, CA 95817, USA
Med Care 47:1237-43. 2009..However, few studies have evaluated the accuracy of these ICD-9-CM codes across multiple hospitals... - Racial and gender differences in the incidence of recurrent venous thromboembolismRichard H White
Department of Medicine, UC Davis, Davis, California, USA
Thromb Haemost 96:267-73. 2006..The effect of gender on the risk of recurrent venous thromboembolism can not be generalized because it varies between racial/ethnic groups and with the type of index event... - Effect of weight, sex, age, clinical diagnosis, and thromboplastin reagent on steady-state intravenous heparin requirementsR H White
Division of General Medicine, University of California, Davis, USA
Arch Intern Med 157:2468-72. 1997..Less is known about whether sex, age, clinical diagnosis, and the thromboplastin used to measure the activated partial thromboplastin time (aPTT) affect heparin dose requirements... - Length of hospital stay for treatment of deep venous thrombosis and the incidence of recurrent thromboembolismR H White
Division of General Medicine, University of California at Davis, Sacramento 95817, USA
Arch Intern Med 158:1005-10. 1998..Current guidelines suggest that all patients with acute deep venous thrombosis should be treated with intravenous heparin for at least 5 days, overlapping with warfarin sodium for 4 to 5 days... - Incidence of venous thromboembolism in the year before the diagnosis of cancer in 528,693 adultsRichard H White
Departments of Internal Medicine, Medicine, Medicine and Statistics, and Public Health Sciences, University of California Davis, Sacramento, CA 95817, USA
Arch Intern Med 165:1782-7. 2005..It is unclear how frequently unprovoked venous thromboembolism (VTE) reflects the presence of an occult cancer... - A population-based study of the effectiveness of inferior vena cava filter use among patients with venous thromboembolismR H White
Division of General Medicine, Suite 2400, PSSB, 4150 V St, Sacramento, CA 95817, USA
Arch Intern Med 160:2033-41. 2000..There are few population-based data regarding the effectiveness of inferior vena cava filter use in the prevention of symptomatic pulmonary embolism... - Temporary reversal of anticoagulation using oral vitamin KR H White
University of California, Davis, Sacramento, California, USA
J Thromb Thrombolysis 10:149-53. 2000..5 (r=-0.52, p=0.011). Use of a 2.0 mg oral dose of vitamin K(1) does not reliably reverse (correct) a therapeutic INR in patients maintained on their daily dose of warfarin... - Predictors of rehospitalization for symptomatic venous thromboembolism after total hip arthroplastyR H White
Department of Medicine, University of California, Davis, Sacramento, USA
N Engl J Med 343:1758-64. 2000..Risk factors associated with these symptomatic thromboembolic events are not well defined... - Evaluation of the predictive value of ICD-9-CM coded administrative data for venous thromboembolism in the United StatesRichard H White
Division of General Medicine, University of California, Davis, CA, USA
Thromb Res 126:61-7. 2010..To determine the positive predictive value of International Classification of Disease, 9th Revision, Clinical Modification (ICD-9-CM) discharge codes for acute deep vein thrombosis or pulmonary embolism... - Recurrent venous thromboembolism after surgery-provoked versus unprovoked thromboembolismR H White
Department of Medicine, UC Davis School of Medicine, Sacramento, CA, USA
J Thromb Haemost 8:987-97. 2010..The incidence of recurrent venous thromboembolism (VTE) varies depending on the nature of the initial provoking risk factor(s)... - ICD-9-CM codes poorly indentified venous thromboembolism during pregnancyRichard H White
Division of General Medicine, University of California Davis, Suite 2400, 4150 V Street, Sacramento, CA 95817, USA
J Clin Epidemiol 57:985-8. 2004..There is little data regarding the accuracy of pregnancy-specific ICD-9-CM codes used to identify patients with venous thromboembolism (VTE)... - The incidence of venous thromboembolism among patients with primary lung cancerH K Chew
Division of Hematology Oncology, Department of Internal Medicine, University of California Davis, Sacramento, CA, USA
J Thromb Haemost 6:601-8. 2008..Objectives: To determine the incidence of VTE and the risk factors associated with development of VTE in a large population-based study of patients with non-small cell and small cell lung cancer... - The incidence and case-fatality rates of acute biliary, alcoholic, and idiopathic pancreatitis in California, 1994-2001Charles F Frey
Department of Surgery, UC Davis Medical Center, Sacramento, CA, USA
Pancreas 33:336-44. 2006..However, there was no reduction in the 14- or 91-day case-fatality rate. Further research is needed to explain both the rise in the incidence rate of pancreatitis and the absence of any improvement in the early case-fatality rate... - Venous thromboembolism in patients with colorectal cancer: incidence and effect on survivalAllison Alcalay
Division of Hematology and Oncology, Department of Internal Medicine, University of California, Davis, Sacramento, CA 95817, USA
J Clin Oncol 24:1112-8. 2006..Incident VTE reduced survival among patients with local or regional disease, suggesting that, in these patients, VTE may reflect the presence of a biologically more aggressive cancer... - Risk of cancer among rheumatoid arthritis patients in CaliforniaArti Parikh-Patel
California Cancer Registry, Public Health Institute, 1825 Bell Street, Suite 102, Sacramento, CA 95825, USA
Cancer Causes Control 20:1001-10. 2009..The objective of this retrospective cohort study was to evaluate cancer risk among rheumatoid arthritis (RA) patients in California... - Anticoagulation in the elderlyM C Henderson
Department of Internal Medicine, University of California Davis, 4150 V Street, Sacramento, CA 95817, USA
Curr Opin Pulm Med 7:365-70. 2001..This information should enable practitioners to better assess the relative risks and benefit of oral anticoagulation therapy to guide treatment decisions in the elderly... - Optimization of inpatient warfarin therapy: impact of daily consultation by a pharmacist-managed anticoagulation serviceW E Dager
Department of Pharmaceutical Services, University of California, Davis Medical Center, Sacramento 95817, USA
Ann Pharmacother 34:567-72. 2000..To determine the effect of daily consultation by a team of hospital pharmacists on the accuracy and rapidity of optimizing warfarin therapy... - Deep vein thrombosis and pulmonary embolism in two cohorts: the longitudinal investigation of thromboembolism etiologyMary Cushman
Department of Medicine, University of Vermont, Burlington, USA
Am J Med 117:19-25. 2004..To determine the incidence of deep vein thrombosis and pulmonary embolism in two cohorts representing regions of the United States... - Venous thromboembolism after spinal cord injury: incidence, time course, and associated risk factors in 16,240 adults and childrenTracey Jones
Department of Physical Medicine and Rehabilitation, Center for Health Services Research in Primary Care, University of California, Davis, CA, USA
Arch Phys Med Rehabil 86:2240-7. 2005..We identified specific risk factors for VTE. Further studies are needed to determine if prompt initiation of medical prophylaxis in high risk subjects reduces the incidence of symptomatic VTE... - Risk of stroke after surgery in patients with and without chronic atrial fibrillationS Kaatz
Department of Medicine, Henry Ford Hospital, Detroit, MI 48202, USA
J Thromb Haemost 8:884-90. 2010..The extent to which chronic atrial fibrillation affects the risk of postoperative stroke is largely unknown... - Early morbidity after total hip replacement: rheumatoid arthritis versus osteoarthritisR H White
Department of Internal Medicine, University of California, Davis
J Gen Intern Med 5:304-9. 1990..The short-term outcome of patients with rheumatoid arthritis appears comparable to that of patients with osteoarthritis... - Low-molecular-weight heparin-induced thrombocytopenia in a childWilliam E Dager
Department of Pharmaceutical Services, University of California, Davis Medical Center, Sacramento, CA 95817 2201, USA
Ann Pharmacother 38:247-50. 2004..To report a case of probable acute venous thrombosis caused by heparin-induced thrombocytopenia (HIT) in a pediatric patient with a normal platelet count after prolonged enoxaparin therapy... - Venous thromboembolism (VTE) in patients with cancer: epidemiology and risk factorsTed Wun
Division of Hematology and Oncology, Department of Internal Medicine, University of California, Davis, California 95187, USA
Cancer Invest 27:63-74. 2009..Development of VTE is clearly associated with decreased survival and this effect is greater among patients initially diagnosed with local or regional stage cancer compared to patients with metastatic cancer... - Pharmacotherapy of heparin- induced thrombocytopeniaWilliam E Dager
Anticoagulation Service, UC Davis Medical Center, UC Davis School of Medicine, Sacramento CA, USA
Expert Opin Pharmacother 4:919-40. 2003.... - An economic model of adverse events and costs for oral anticoagulants used for atrial fibrillationJ Paul Leigh
Center for Healthcare Policy and Research and Department of Public Health Sciences, University of California, Davis, CA 95616 5270, USA
Curr Med Res Opin 23:2071-81. 2007..To construct a semi-Markov model to compare health outcomes and medical costs associated with warfarin and a second anticoagulant over 1- and 5-year periods... - The effects of race/ethnicity and sex on the risk of venous thromboembolismCraig R Keenan
Division of General Internal Medicine, University of California, Davis, Sacramento, California 95817, USA
Curr Opin Pulm Med 13:377-83. 2007..We review the influence of race/ethnicity and sex on venous thromboembolism, concentrating on articles from 2005 to 2007... - Patient self-management of oral anticoagulationTonya L Fancher
Division of General Medicine, University of California, Davis Patient Support Services Building, Suite 2400, Sacramento, CA 95817, USA
Curr Hematol Rep 3:368-74. 2004..This article reviews the evidence behind the efficacy, safety, and cost effectiveness of PSM... 
N-of-1 trials of expensive biological therapies: a third way?Richard L Kravitz
Division of General Medicine and Center for Healthcare Policy and Research, University of California, Davis, School of Medicine, Sacramento, CA 95817, USA
Arch Intern Med 168:1030-3. 2008..In the primary model, the n-of-1 trial option was 15% more expensive than stepped care but 47% cheaper than open access to etanercept. More research is needed on the acceptability, safety, and generalizability of this promising approach...- Venous thromboembolism in patients with acute leukemia, lymphoma, and multiple myelomaTed Wun
Division of Hematology and Oncology, UC Davis School of Medicine, Sacramento, CA 95670, USA
Thromb Res 125:S96-102. 2010..Primary and secondary pharmacological prophylaxis can be problematic in these patients who are often thrombocytopenic. Strategies to prevent VTE, especially upper extremity catheter-associated thrombosis need to be developed... - Cancer risk in a cohort of patients with systemic lupus erythematosus (SLE) in CaliforniaArti Parikh-Patel
California Cancer Registry, Public Health Institute, 1700 Tribute Road, Suite100, Sacramento, CA 95815 4402, USA
Cancer Causes Control 19:887-94. 2008..We conducted a retrospective cohort study to examine cancer risk in a large cohort of systemic lupus erythematosus (SLE) patients in California... - Risk factors for venous thromboembolism after total hip and knee replacement surgeryRichard H White
Division of General Medicine, University of California, Sacramento, California 95817, USA
Curr Opin Pulm Med 8:365-71. 2002..Factors associated with lower risk include (1) Asian/Pacific Islander ethnicity, (2) use of pneumatic compression among non-obese patients after surgery, and (3) extended thromboprophylaxis after hospital discharge... - Venous thromboembolism in ovarian cancerAnne O Rodriguez
Department of Obstetrics and Gynecology, University of California Davis, USA
Gynecol Oncol 105:784-90. 2007..To determine the incidence, time-course, and risk factors associated with the development of thromboembolism (VTE) in a population-based study of women with ovarian cancer... - Treatment of heparin-induced thrombocytopeniaWilliam E Dager
Department of Pharmaceutical Services, The University of California, Davis Medical Center, Sacramento 95817, USA
Ann Pharmacother 36:489-503. 2002..To describe heparin-induced thrombocytopenia (HIT or HIT-2), an immune-mediated adverse reaction to heparin or low-molecular-weight heparin. Available treatment options and considerations in developing a therapy approach are discussed... - Incidence of venous thromboembolism and its effect on survival among patients with common cancersHelen K Chew
Divisionsof Hematology Oncology, Department of Internal Medicine, and Department of Public Health Sciences, University of California, Davis, Sacramento, CA 95817, USA
Arch Intern Med 166:458-64. 2006..The incidence of venous thromboembolism after diagnosis of specific cancers and the effect of thromboembolism on survival are not well defined... - Age as a risk factor for venous thromboembolism after major surgeryCraig R Keenan
Department of Medicine, Division of General Medicine, University of California, Davis, California 95817, USA
Curr Opin Pulm Med 11:398-402. 2005..This article reviews the recent literature on the effect of age on the incidence of postoperative venous thromboembolism... - Mandating coverage of biologic therapies for rheumatic disease: where evidence and politics meetYali A Bair
Center for Health Services Research in Primary Care, University of California Davis, 2103 Stockton Boulevard, Sacramento, CA 95817, USA
Arthritis Rheum 55:353-4. 2006..We hope that the readership of Arthritis Care & Research find this article informative as an exemplar of the policies that could dramatically alter the welfare of our patients... - Tinzaparin in outpatients with pulmonary embolism or deep vein thrombosisWilliam E Dager
Department of Pharmaceutical Services, University of California Davis Medical Center, Sacramento, CA95817 2201, USA
Ann Pharmacother 39:1182-7. 2005..Data regarding outpatient use of any LMWH in pulmonary embolism (PE) or tinzaparin in DVT while transitioning therapy to a vitamin K antagonist are limited... - Combined use of rapid D-dimer testing and estimation of clinical probability in the diagnosis of deep vein thrombosis: systematic reviewTonya L Fancher
Division of General Medicine, University of California at Davis, Patient Support Services Building, Suite 2400, Sacramento, California 95817, USA
BMJ 329:821. 2004..To summarise the evidence supporting the use of rapid d-dimer testing combined with estimation of clinical probability to exclude the diagnosis of deep venous thrombosis among outpatients... - Incidence of venous thromboembolism and the impact on survival in breast cancer patientsHelen K Chew
Division of Hematology Oncology, University of California Davis, CA, USA
J Clin Oncol 25:70-6. 2007..The incidence of venous thromboembolism (VTE) and the risk factors associated with development of VTE have not been reported in a large population-based study of breast cancer patients... - Argatroban for heparin-induced thrombocytopenia in hepato-renal failure and CVVHDWilliam E Dager
Department of Pharmaceutical Services, University of California Davis Medical Center, Sacramento, CA 95817 2201, USA
Ann Pharmacother 37:1232-6. 2003..To report a case of significant hepatic and renal failure with the use of argatroban in a patient with heparin-induced thrombocytopenia (HIT) requiring continuous veno-veno hemodialysis (CVVHD)... - Use of lepirudin in patients with heparin-induced thrombocytopenia and renal failure requiring hemodialysisW E Dager
Department of Pharmaceutical Services, University of California Davis Medical Center, Sacramento, CA 95817 2201, USA
Ann Pharmacother 35:885-90. 2001..To report two cases of successful lepirudin use in two patients with heparin-induced thrombocytopenia (HIT) and renal failure... - DVT prophylaxis and anticoagulation in the surgical patientPeter Kaboli
Division of General Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
Med Clin North Am 87:77-110, viii. 2003..Finally, we review the perioperative management of patients on long-term oral anticoagulation... - Do patients followed in anticoagulation clinics for antiphospholipid syndrome meet criteria for the disorder?Andrew S Dunn
Division of General Medicine, Mount Sinai School of Medicine, 1470 Madison Ave, Box 1087, New York, NY 10029, USA
Thromb Haemost 94:548-54. 2005..A quality improvement program that includes review of cases referred for chronic anticoagulation care is recommended to ensure appropriate testing and treatment of patients with suspected APS... - Co-morbidity is a strong predictor of early death and multi-organ system failure among patients with acute pancreatitisCharles Frey
Department of Surgery, University of California Davis, Davis, CA, USA
J Gastrointest Surg 11:733-42. 2007..We conclude that advancing age and the number of chronic comorbid conditions are very strong predictors of early death among patients with acute pancreatitis... - Epidemiology of venous thromboembolism in 9489 patients with malignant gliomaThomas J Semrad
Department of Internal Medicine, University of California Davis School of Medicine, Sacramento, California 95817, USA
J Neurosurg 106:601-8. 2007..The authors sought to define the incidence of symptomatic venous thromboembolism (VTE) in patients harboring malignant gliomas... - High risk for venous thromboembolism in diabetics with hyperosmolar state: comparison with other acute medical illnessesC R Keenan
Division of General Internal Medicine, University of California, Davis, Sacramento, CA, USA
J Thromb Haemost 5:1185-90. 2007..Objectives: To determine the risk of VTE in patients hospitalized for diabetes with hyperosmolar state compared to patients with other acute medical illnesses... - Venous ultrasound testing for suspected thrombosis: incidence of significant non-thrombotic findingsMark E Sutter
Department of Emergency Medicine, University of California, Davis Medical Center, Sacramento, California 95817, USA
J Emerg Med 36:55-9. 2009..Further research is needed to determine if D-dimer plus a clinical probability tool will include or exclude the patients with clinically significant major findings... - Validation of the Canadian clinical probability model for acute venous thrombosisG Patrick Shields
University of California, Davis, USA
Acad Emerg Med 9:561-6. 2002..CONCLUSIONS: Use of the Canadian probability model for DVT in this ED resulted in effective risk stratification, comparable to previously published results... - Epidemiology of cancer-related venous thromboembolismTed Wun
Division of Hematology and Oncology, Departments of Internal Medicine and Pathology, Clinical and Translational Sciences Center CTSC, University of California, Davis Cancer Center, 4501 X Street, Sacramento, CA 95187, USA
Best Pract Res Clin Haematol 22:9-23. 2009..Finally, a small percentage of patients with idiopathic VTE and no clinical or laboratory evidence of cancer may harbour an aggressive but 'occult' malignancy likely causally linked to the development of VTE... - The incidence of venous thromboembolism and its effect on survival among patients with primary bladder cancerRasanamar Sandhu
Department of Internal Medicine, Division of Hematology Oncology, University of California Davis, Sacramento, California, USA
Cancer 116:2596-603. 2010..The incidence, risk factors, time course, and impact on survival of venous thromboembolism (VTE) in a large, population-based study of patients with bladder cancer have not been identified previously... - Venous thromboembolism in patients with acute leukemia: incidence, risk factors, and effect on survivalGrace H Ku
Division of Hematology and Oncology, School of Medicine, University of California San Diego, CA, USA
Blood 113:3911-7. 2009..In the patients with ALL, development of VTE was associated with a 40% increase in the risk of dying within 1 year. The incidence of VTE in acute leukemia is appreciable, and is comparable with the incidence in many solid tumors... - Electronic alerts to prevent venous thromboembolismRichard H White
N Engl J Med 352:2349-50; author reply 2349-50. 2005 - Protein C, antithrombin, and venous thromboembolism incidence: a prospective population-based studyAaron R Folsom
Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
Arterioscler Thromb Vasc Biol 22:1018-22. 2002..Attributable risk estimates suggest that low protein C levels account for approximately 2.5% of venous thromboembolic events in the ARIC population... - Comparison of outcomes after hospitalization for deep venous thrombosis or pulmonary embolismSusan Murin
Thromb Haemost 88:407-14. 2002..Venous thrombosis and pulmonary embolism appear to be distinct, albeit overlapping, clinical entities with different natural histories... - Seasonal dynamics of soil micronutrients in compost-amended bermudagrass turfTony L Provin
Department of Soil and Crop Sciences, Texas A and M University, 2474 TAMU, College Station, TX 77843 2474, United States
Bioresour Technol 99:2672-9. 2008..Composts only influenced the magnitude of changes in micronutrient concentrations, as similar seasonal trends occurred for both compost-amended and unamended soils... - Compost impacts on dissolved organic carbon and available nitrogen and phosphorus in turfgrass soilAlan L Wright
Everglades Research and Education Center, University of Florida, 3200 E Palm Beach Road, Belle Glade, FL 33430 4702, United States
Waste Manag 28:1057-63. 2008..Seasonal variability of SOC, DOC, and available P was likely related to St. Augustinegrass growth stages as well as precipitation, as declines occurred after precipitation events...