H S White
Affiliation: University of Utah
- Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure thresholdH S White
Department of Pharmacology and Toxicology, University of Utah, College of Pharmacy, Salt Lake City 84112, USA
Epilepsy Res 28:167-79. 1997..Taken together these results support the conclusion that enhancement of GABA-mediated Cl- flux may represent one mechanism that contributes to the anticonvulsant activity of topiramate...
- Pharmacological characterization of the 6 Hz psychomotor seizure model of partial epilepsyM E Barton
Anticonvulsant Screening Project, Department of Pharmacology and Toxicology, University of Utah, 30 S 2000 E Room 201, Salt Lake City, UT 84112, USA
Epilepsy Res 47:217-27. 2001..The pharmacological results combined with the c-Fos immunohistochemistry suggest that the 6 Hz stimulation may provide a useful model of therapy-resistant limbic seizures...