Brian W Whitcomb

Summary

Affiliation: University of Massachusetts
Country: USA

Publications

  1. pmc Maternal serum granulocyte colony-stimulating factor levels and spontaneous preterm birth
    Brian W Whitcomb
    Epidemiology Branch, DESPR, NICHD, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Rockville, Maryland
    J Womens Health (Larchmt) 18:73-8. 2009
  2. doi request reprint Assessment of skewed exposure in case-control studies with pooling
    Brian W Whitcomb
    Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts Amherst, Amherst, MA, USA
    Stat Med 31:2461-72. 2012
  3. pmc Association between bilirubin and cardiovascular disease risk factors: using Mendelian randomization to assess causal inference
    Patrick F McArdle
    Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, 660 West Redwood Street, RM, 492, Baltimore, MD 21201, USA
    BMC Cardiovasc Disord 12:16. 2012
  4. pmc Quantification of collider-stratification bias and the birthweight paradox
    Brian W Whitcomb
    Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003 9304, USA
    Paediatr Perinat Epidemiol 23:394-402. 2009
  5. pmc Ovarian function and cigarette smoking
    Brian W Whitcomb
    Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts at Amherst, MA, USA
    Paediatr Perinat Epidemiol 24:433-40. 2010
  6. pmc Treatment of batch in the detection, calibration, and quantification of immunoassays in large-scale epidemiologic studies
    Brian W Whitcomb
    Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003 9304, USA
    Epidemiology 21:S44-50. 2010
  7. doi request reprint Realignment and multiple imputation of longitudinal data: an application to menstrual cycle data
    Sunni L Mumford
    Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, MD 20852, USA
    Paediatr Perinat Epidemiol 25:448-59. 2011
  8. pmc Endogenous reproductive hormones and C-reactive protein across the menstrual cycle: the BioCycle Study
    Audrey J Gaskins
    Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, USA
    Am J Epidemiol 175:423-31. 2012
  9. pmc Effect of daily fiber intake on reproductive function: the BioCycle Study
    Audrey J Gaskins
    Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA
    Am J Clin Nutr 90:1061-9. 2009
  10. pmc The use of follicle flushing during oocyte retrieval in assisted reproductive technologies: a systematic review and meta-analysis
    Gary Levy
    Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Hum Reprod 27:2373-9. 2012

Detail Information

Publications21

  1. pmc Maternal serum granulocyte colony-stimulating factor levels and spontaneous preterm birth
    Brian W Whitcomb
    Epidemiology Branch, DESPR, NICHD, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Rockville, Maryland
    J Womens Health (Larchmt) 18:73-8. 2009
    ..G-CSF, a hematopoietic cytokine, mediates the increase in leukocytes in pregnancy and may play a role in placentation. We evaluated the association between maternal serum G-CSF in the first and second trimesters and PTB...
  2. doi request reprint Assessment of skewed exposure in case-control studies with pooling
    Brian W Whitcomb
    Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts Amherst, Amherst, MA, USA
    Stat Med 31:2461-72. 2012
    ....
  3. pmc Association between bilirubin and cardiovascular disease risk factors: using Mendelian randomization to assess causal inference
    Patrick F McArdle
    Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, 660 West Redwood Street, RM, 492, Baltimore, MD 21201, USA
    BMC Cardiovasc Disord 12:16. 2012
    ..In this report, we demonstrate its use in assessing direct causal relations between serum bilirubin levels and CVD risk factors, including obesity, cholesterol, measures of vascular function and blood pressure...
  4. pmc Quantification of collider-stratification bias and the birthweight paradox
    Brian W Whitcomb
    Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003 9304, USA
    Paediatr Perinat Epidemiol 23:394-402. 2009
    ..The simulations demonstrate the conditions necessary to give rise to empirical evidence of the paradox...
  5. pmc Ovarian function and cigarette smoking
    Brian W Whitcomb
    Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts at Amherst, MA, USA
    Paediatr Perinat Epidemiol 24:433-40. 2010
    ..These phase-specific differences in levels of LH and FSH in healthy, regularly menstruating women who are current smokers compared with non-smokers reflect one mechanism by which smoking may influence fertility and reproductive health...
  6. pmc Treatment of batch in the detection, calibration, and quantification of immunoassays in large-scale epidemiologic studies
    Brian W Whitcomb
    Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003 9304, USA
    Epidemiology 21:S44-50. 2010
    ..Immunoassays, polymerase chain reaction, and chromatographic approaches are among assays performed in this manner...
  7. doi request reprint Realignment and multiple imputation of longitudinal data: an application to menstrual cycle data
    Sunni L Mumford
    Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, MD 20852, USA
    Paediatr Perinat Epidemiol 25:448-59. 2011
    ..Our method has applications in settings where missing data may occur over time, where daily blood sampling for hormonal measurements is not feasible, and in other areas where timing is essential...
  8. pmc Endogenous reproductive hormones and C-reactive protein across the menstrual cycle: the BioCycle Study
    Audrey J Gaskins
    Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, USA
    Am J Epidemiol 175:423-31. 2012
    ..4, 31.5). These results support the hypothesis that endogenous estradiol might have antiinflammatory effects and highlight the need for standardization of CRP measurement to menstrual cycle phase in reproductive-aged women...
  9. pmc Effect of daily fiber intake on reproductive function: the BioCycle Study
    Audrey J Gaskins
    Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA
    Am J Clin Nutr 90:1061-9. 2009
    ..The influence of fiber on aspects of reproduction, which include ovulation, has not been well studied in premenopausal women...
  10. pmc The use of follicle flushing during oocyte retrieval in assisted reproductive technologies: a systematic review and meta-analysis
    Gary Levy
    Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Hum Reprod 27:2373-9. 2012
    ..STUDY FUNDING/COMPETING INTEREST(S): This work was supported, in part, by the Program in Reproductive and Adult Endocrinology, NICHD, NIH, Bethesda, MD. The authors have no competing interests to declare. TRIAL REGISTRATION NUMBER: N/A...
  11. pmc Z-scores and the birthweight paradox
    Enrique F Schisterman
    Epidemiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Paediatr Perinat Epidemiol 23:403-13. 2009
    ....
  12. pmc Circulating levels of cytokines during pregnancy: thrombopoietin is elevated in miscarriage
    Brian W Whitcomb
    Epidemiology Branch, Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, National Insttutes of Health, Bethesda, Maryland 20852, USA
    Fertil Steril 89:1795-802. 2008
    ..To evaluate the hypothesis that cytokine levels are associated with miscarriage risk using serum samples collected before report of miscarriage...
  13. ncbi request reprint Circulating chemokine levels and miscarriage
    Brian W Whitcomb
    Epidemiology Branch, Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, Bethesda, MD, USA
    Am J Epidemiol 166:323-31. 2007
    ..The observation regarding ENA-78, which has roles in regulation of angiogenesis and leukocyte recruitment, suggests a possible role for this chemokine as an early indicator of miscarriage risk...
  14. pmc Perceived stress and severity of perimenstrual symptoms: the BioCycle Study
    Audra L Gollenberg
    Division of Epidemiology, Statistics and Prevention Research, NICHD, NIH, DHHS, Bethesda, Maryland, USA
    J Womens Health (Larchmt) 19:959-67. 2010
    ..To examine the longitudinal relation between perceived stress in the previous month and perimenstrual symptom severity across two cycles among regularly menstruating, healthy women (n = 259)...
  15. pmc The limitations due to exposure detection limits for regression models
    Enrique F Schisterman
    Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development, National Institutes of Health, 6100 Executive Boulevard, Rm 7B03, Rockville, MD 20852, USA
    Am J Epidemiol 163:374-83. 2006
    ..These results may inform decisions regarding analytical plans for future studies and provide a possible explanation for some amount of the discordance seen in extant literature...
  16. doi request reprint The use of recombinant luteinizing hormone in patients undergoing assisted reproductive techniques with advanced reproductive age: a systematic review and meta-analysis
    Micah J Hill
    Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    Fertil Steril 97:1108-14.e1. 2012
    ..To evaluate the effect of recombinant LH in assisted reproduction technology (ART) cycles in patients of advanced reproductive age...
  17. pmc Assays with lower detection limits: implications for epidemiological investigations
    Brian W Whitcomb
    Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development, National Institutes of Health, Rockville, MD 20852, USA
    Paediatr Perinat Epidemiol 22:597-602. 2008
    ....
  18. pmc Inflammation and early-life abuse in women
    Elizabeth R Bertone-Johnson
    Division of Biostatistics and Epidemiology, University of Massachusetts, Amherst, MA 01003 9304, USA
    Am J Prev Med 43:611-20. 2012
    ..Although mechanisms underlying these relationships are unclear, chronic stress may lead to dysregulation of immune function and chronic inflammation...
  19. pmc Lipid adjustment in the analysis of environmental contaminants and human health risks
    Enrique F Schisterman
    Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Environ Health Perspect 113:853-7. 2005
    ..g., nonfasting blood samples), laboratory measurement, and other underlying modeling assumptions when devising a statistical plan for assessing health outcomes in relation to environmental exposures...
  20. pmc Physical activity of pregnant Hispanic women
    Kristine E Lynch
    Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003, USA
    Am J Prev Med 43:434-9. 2012
    ..However, factors influencing activity in pregnant Hispanic women, who have high rates of sedentary activity as compared to non-Hispanic whites, are not well characterized...
  21. pmc Effects of low-dose aspirin in in-vitro fertilization
    Enrique F Schisterman
    Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, USA
    Curr Opin Obstet Gynecol 21:275-8. 2009
    ..It is hypothesized that this effect on blood flow will improve success rates...