Research Topics
Species | James B WetmoreSummaryAffiliation: University of Kansas Medical Center Country: USA Publications
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Publications
Atrial fibrillation and risk of stroke in dialysis patientsJames B Wetmore
Department of Medicine, Division of Nephrology and Hypertension, University of Kansas School of Medicine, Kansas City, KS, USA
Ann Epidemiol 23:112-8. 2013..Both stroke and chronic atrial fibrillation (AF) are common in dialysis patients, but uncertainty exists in the incidence of new strokes and the risk conferred by chronic AF...
Geographic variation in HMG-CoA reductase inhibitor use in dialysis patientsJames B Wetmore
Department of Medicine, Division of Nephrology and Hypertension, University of Kansas School of Medicine, Mailstop 3002, 3901 Rainbow Blvd, Kansas City, KS, 66160, USA
J Gen Intern Med 27:1475-83. 2012..Little is known about the demographic, clinical, and geographic factors associated with statin exposure in end-stage renal disease (ESRD) patients...
The prevalence of and factors associated with chronic atrial fibrillation in Medicare/Medicaid-eligible dialysis patientsJames B Wetmore
Division of Nephrology and Hypertension, Department of Medicine, University of Kansas School of Medicine, Kansas City, Kansas 66160, USA
Kidney Int 81:469-76. 2012....
Associations of interleukin-6, C-reactive protein and serum amyloid A with mortality in haemodialysis patientsJames B Wetmore
Department of Medicine, San Francisco VAMC University of California, California, USA
Nephrology (Carlton) 13:593-600. 2008..We undertook a prospective study to determine whether these markers could predict mortality in ESRD...
Geographic variation in cardioprotective antihypertensive medication usage in dialysis patientsJames B Wetmore
Department of Medicine, Division of Nephrology and Hypertension, University of Kansas School of Medicine, Kansas City, KS 66160, USA
Am J Kidney Dis 58:73-83. 2011..We constructed a novel database that permits detailed exploration into the demographic, clinical, and geographic factors associated with the use of these agents in hypertensive long-term dialysis patients...
Association of 25-hydroxyvitamin D deficiency with NT-pro BNP levels in patients with acute myocardial infarction: a cross-sectional analysisJames B Wetmore
Division of Nephrology and Hypertension, University of Kansas Medical Center, Kansas City, KS, USA
BMC Res Notes 4:542. 2011..abstract:..
Role of lean body mass in estimating glomerular filtration rate in Alzheimer diseaseJames B Wetmore
Department of Medicine, Division of Nephrology and Hypertension and The Kidney Institute, University of Kansas Medical Center, Kansas City, KS 66160, USA
Nephrol Dial Transplant 26:2222-31. 2011..Since AD is characterized by sarcopenia and other changes in body composition, which are known to influence GFR, a determination of how lean mass (LM) affects estimation of GFR in AD patients is important...
Elevated FGF23 levels are associated with impaired calcium-mediated suppression of PTH in ESRDJames B Wetmore
Division of Nephrology and Hypertension, University of Kansas School of Medicine, Kansas City, Kansas 66160, USA
J Clin Endocrinol Metab 96:E57-64. 2011..The positive association of elevated fibroblast growth factor-23 (FGF23) with PTH levels in the setting of secondary hyperparathyroidism is paradoxical to the purported effects of FGF23 to suppress PTH secretion...
Effects of cinacalcet and concurrent low-dose vitamin D on FGF23 levels in ESRDJames B Wetmore
University of Kansas Medical Center, MS 3002, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA
Clin J Am Soc Nephrol 5:110-6. 2010..The effects of various treatments for secondary hyperparathyroidism on FGF23 levels in ESRD have not been examined in a clinical trial...
The ABCs of cardioprotection in dialysis patients: a systematic reviewJames B Wetmore
Department of Medicine, Division of Nephrology and Hypertension, University of Kansas School of Medicine, Kansas City, KS 66160, USA
Am J Kidney Dis 53:457-66. 2009....
An angiotensin converting enzyme haplotype predicts survival in patients with end stage renal diseaseJames B Wetmore
The Department of Medicine, San Francisco VAMC University of California, San Francisco, CA 94121, USA
Hum Genet 120:201-10. 2006..This "protective" haplotype may encompass loci with functional significance in the ACE gene...
Association of race with cumulative exposure to statins in dialysisJames B Wetmore
Division of Nephrology and Hypertension, Department of Medicine, University of Kansas School of Medicine, Kansas City, USA
Am J Nephrol 36:90-6. 2012....
Considering health insurance: how do dialysis initiates with Medicaid coverage differ from persons without Medicaid coverage?James B Wetmore
Division of Nephrology and Hypertension, Department of Medicine, University of Kansas School of Medicine, KS, USA
Nephrol Dial Transplant 25:198-205. 2010..How these patients differ from non-Medicaid-enrolled incident dialysis patients and how these differences have changed over time have not been systematically examined...
Economic analysis of cinacalcet in combination with low-dose vitamin D versus flexible-dose vitamin D in treating secondary hyperparathyroidism in hemodialysis patientsTheresa I Shireman
Department of Preventive Medicine and Public Health and the Landon Center on Aging, University of Kansas Medical Center, Kansas City, KS, USA
Am J Kidney Dis 56:1108-16. 2010..The economic implications of these treatment regimens have not been explored...
Transient impact of automated glomerular filtration rate reporting on drug dosing for hospitalized older adults with concealed renal insufficiencyJessica L Kalender-Rich
Division of General and Geriatric Medicine, Department of Internal Medicine, University of Kansas School of Medicine, Kansas City, Kansas, USA
Am J Geriatr Pharmacother 9:320-7. 2011..Older adults with concealed renal insufficiency are at risk of medication dosing errors. It is not known whether automated estimated glomerular filtration rate (eGFR) reporting is associated with reduced dosing errors in this population...
Impact of race on cumulative exposure to antihypertensive medications in dialysisJames B Wetmore
Department of Medicine, Division of Nephrology and Hypertension, University of Kansas School of Medicine, Kansas City, KS, USA
Am J Hypertens 26:234-42. 2013..However, cumulative exposure has not been investigated in dialysis patients...
Interleukin-1 gene cluster polymorphisms predict risk of ESRDJames B Wetmore
Department of Medicine, San Francisco VAMC University of California, San Francisco, California 94121, USA
Kidney Int 68:278-84. 2005..Inflammation is regulated in part by genes of the interleukin-1 (IL-1) gene cluster. We hypothesized that polymorphisms in this gene cluster may be associated with risk of end-stage renal disease (ESRD)...
Discrepancies between creatinine- and cystatin C-based equations: implications for identification of chronic kidney disease in the general populationJames B Wetmore
Division of Nephrology and Hypertension, Department of Medicine, University of Kansas School of Medicine, Kansas City, Kansas, USA
Scand J Urol Nephrol 44:242-50. 2010....
Does it matter how parathyroid hormone levels are suppressed in secondary hyperparathyroidism?Jason R Stubbs
Division of Nephrology and Hypertension and The Kidney Institute, University of Kansas Medical Center, Kansas City, Kansas, USA
Semin Dial 24:298-306. 2011..We also examine the potential nonclassical effects of these therapies on the renin-angiotensin-aldosterone system, proteinuria, vascular calcification, fibroblast growth factor-23, inflammation, and overall survival...
Calcimimetics or vitamin D analogs for suppressing parathyroid hormone in end-stage renal disease: time for a paradigm shift?James B Wetmore
Division of Nephrology and Hypertension, University of Kansas Medical Center, Kansas City, KS 66160, USA
Nat Clin Pract Nephrol 5:24-33. 2009..Finally, we propose a novel treatment framework in which calcimimetics are the primary therapy for suppressing parathyroid hormone production in patients with end-stage renal disease...
Impact of a modified data capture period on Liu comorbidity index scores in Medicare enrollees initiating chronic dialysisSally K Rigler
Department of General and Geriatric Medicine, University of Kansas School of Medicine, 3901 Rainbow Boulevard, MS 1037, Kansas City, KS 66160, USA
BMC Nephrol 14:51. 2013..The 270 day survival requirement results in sample size reductions and potential survivor bias. An earlier and shorter time-frame for data capture could be beneficial, if sufficiently similar comorbidity information could be ascertained...
Association of decreased glomerular filtration rate with racial differences in survival after acute myocardial infarctionJames B Wetmore
Division of Nephrology, Department of Medicine, University of Kansas School of Medicine, Kansas City, Kansas, USA
Clin J Am Soc Nephrol 6:733-40. 2011..However, whether there are racial differences in the prevalence or prognostic importance of renal insufficiency in AMI is unknown...
A CD3+ count-based thymoglobulin induction regimen permits delayed introduction of calcineurin inhibitors in kidney transplantationConnie J Wang
Division of Nephrology and Hypertension, Department of Pathology, University of Kansas Medical Center, Kansas City, KS 66160, USA
Clin Transplant 26:900-9. 2012..Here, we report our results of a novel CNI-sparing induction protocol, which utilizes a CD3+ cell count-based rATG treatment regimen when delayed graft function (DGF) develops in the immediate postoperative period...
Effects of short-term alendronate on bone mineral density in haemodialysis patientsJames B Wetmore
Department of Medicine, University of California, San Francisco, California 94143, USA
Nephrology (Carlton) 10:393-9. 2005..Further studies of longer duration, and including examination of bone histology, are needed to assess whether bisphosphonates can be used to preserve BMD in dialysis patients...
Painless myocardial ischemia is associated with mortality in patients with chronic kidney diseaseJames B Wetmore
Division of Nephrology and Hypertension, University of Kansas Medical Center, Kansas City, Kans, USA
Nephron Clin Pract 122:9-16. 2012..These findings may partially explain the high mortality traditionally attributed to cardiovascular disease in CKD patients...
Treatment of secondary hyperparathyroidism in kidney disease: what we know and do not know about use of calcimimetics and vitamin D analogsJames B Wetmore
Department of Medicine, Division of Nephrology, University of Kansas Medical Center, Kansas City, KS, USA
Int J Nephrol Renovasc Dis 1:5-17. 2008....
Implications of donor disseminated intravascular coagulation on kidney allograft recipientsConnie J Wang
Division of Nephrology and Hypertension, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
Clin J Am Soc Nephrol 6:1160-7. 2011..The significance of donor DIC on recipient kidney function is poorly understood. Additionally, the significance of thrombocytopenia in recipients of kidneys from DIC-positive donors is understudied...
