Stefan Westermann

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Post-translational modifications regulate microtubule function
    Stefan Westermann
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    Nat Rev Mol Cell Biol 4:938-47. 2003
  2. ncbi request reprint Architecture of the Dam1 kinetochore ring complex and implications for microtubule-driven assembly and force-coupling mechanisms
    Hong Wei Wang
    Life Sciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, California 94720, USA
    Nat Struct Mol Biol 14:721-6. 2007
  3. ncbi request reprint The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends
    Stefan Westermann
    Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California 94720 3202, USA
    Nature 440:565-9. 2006
  4. pmc Architecture and flexibility of the yeast Ndc80 kinetochore complex
    Hong Wei Wang
    Life Science Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA
    J Mol Biol 383:894-903. 2008
  5. ncbi request reprint Structures and functions of yeast kinetochore complexes
    Stefan Westermann
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    Annu Rev Biochem 76:563-91. 2007
  6. pmc A protein interaction map of the mitotic spindle
    Jonathan Wong
    Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA
    Mol Biol Cell 18:3800-9. 2007
  7. ncbi request reprint Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex
    Stefan Westermann
    Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA
    Mol Cell 17:277-90. 2005
  8. pmc Architecture of the budding yeast kinetochore reveals a conserved molecular core
    Stefan Westermann
    Department of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, Berkeley, CA 94720, USA
    J Cell Biol 163:215-22. 2003
  9. ncbi request reprint Identification of CfNek, a novel member of the NIMA family of cell cycle regulators, as a polypeptide copurifying with tubulin polyglutamylation activity in Crithidia
    Stefan Westermann
    Max Planck Institute for Biophysical Chemistry, Department of Biochemistry, Am Fassberg 11, 37077 Goettingen, Germany
    J Cell Sci 115:5003-12. 2002
  10. pmc Stefan Westermann: a close look at kinetochore function. Interviewed by Caitlan Sedwick
    Stefan Westermann
    J Cell Biol 179:810-1. 2007

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Post-translational modifications regulate microtubule function
    Stefan Westermann
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    Nat Rev Mol Cell Biol 4:938-47. 2003
  2. ncbi request reprint Architecture of the Dam1 kinetochore ring complex and implications for microtubule-driven assembly and force-coupling mechanisms
    Hong Wei Wang
    Life Sciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, California 94720, USA
    Nat Struct Mol Biol 14:721-6. 2007
    ..One of Ipl1's roles might be to fine-tune the coupling of the microtubule interaction with the conformational change required for oligomerization, with phosphorylation resulting in ring breakdown...
  3. ncbi request reprint The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends
    Stefan Westermann
    Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California 94720 3202, USA
    Nature 440:565-9. 2006
    ..The Dam1 ring complex is a molecular device that can translate the force generated by microtubule depolymerization into movement along the lattice to facilitate chromosome segregation...
  4. pmc Architecture and flexibility of the yeast Ndc80 kinetochore complex
    Hong Wei Wang
    Life Science Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720, USA
    J Mol Biol 383:894-903. 2008
    ..We hypothesize that the kink in Ndc80 is essential for correct kinetochore geometry and could be part of a tension-sensing mechanism at the kinetochore...
  5. ncbi request reprint Structures and functions of yeast kinetochore complexes
    Stefan Westermann
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA
    Annu Rev Biochem 76:563-91. 2007
    ..Here we review the current understanding of kinetochore function in budding yeast and draw comparisons to recent findings in other organisms...
  6. pmc A protein interaction map of the mitotic spindle
    Jonathan Wong
    Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA
    Mol Biol Cell 18:3800-9. 2007
    ..The wealth of protein interactions presented here highlights the extent to which mitotic spindle protein functions and regulation are integrated with each other and with other cellular activities...
  7. ncbi request reprint Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex
    Stefan Westermann
    Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA
    Mol Cell 17:277-90. 2005
    ..These observations suggest a mechanism by which the kinetochore can recognize and stay attached to the plus ends of microtubules...
  8. pmc Architecture of the budding yeast kinetochore reveals a conserved molecular core
    Stefan Westermann
    Department of Molecular and Cell Biology, Barker Hall, University of California, Berkeley, Berkeley, CA 94720, USA
    J Cell Biol 163:215-22. 2003
    ..We propose that a molecular core consisting of CENP-A, -C, -H, and Ndc80/HEC has been conserved from yeast to humans to link centromeres to spindle microtubules...
  9. ncbi request reprint Identification of CfNek, a novel member of the NIMA family of cell cycle regulators, as a polypeptide copurifying with tubulin polyglutamylation activity in Crithidia
    Stefan Westermann
    Max Planck Institute for Biophysical Chemistry, Department of Biochemistry, Am Fassberg 11, 37077 Goettingen, Germany
    J Cell Sci 115:5003-12. 2002
    ..After purification on a Ni(2+)-column the recombinant enzyme preparation displays ATP-dependent tubulin polyglutamylation activity as well as casein-phosphorylation activity...
  10. pmc Stefan Westermann: a close look at kinetochore function. Interviewed by Caitlan Sedwick
    Stefan Westermann
    J Cell Biol 179:810-1. 2007
    b>Stefan Westermann is probing the structure and function of the yeast kinetochore.