West T, Ernst R, Jansson Hutson M, Skerrett S. Activation of Toll-like receptors by Burkholderia pseudomallei. BMC Immunol. 2008;9:46 pubmed publisher
..Other MyD88-dependent signaling pathways may also be important in the host response to B. pseudomallei infection. These findings provide new insights into critical mechanisms of host defense in melioidosis. ..
West T, Hawn T, Skerrett S. Toll-like receptor signaling in airborne Burkholderia thailandensis infection. Infect Immun. 2009;77:5612-22 pubmed publisher
..TLR signaling in B. thailandensis infection is substantially comparable to signaling induced by virulent B. pseudomallei. These studies provide additional insights into the host-pathogen interaction in pneumonic Burkholderia infection...
West T, Frevert C, Liggitt H, Skerrett S. Inhalation of Burkholderia thailandensis results in lethal necrotizing pneumonia in mice: a surrogate model for pneumonic melioidosis. Trans R Soc Trop Med Hyg. 2008;102 Suppl 1:S119-26 pubmed publisher
..These findings demonstrate that airborne B. thailandensis infection in mice provides an accessible surrogate model of melioidosis. ..
West T, Myers N, Limmathurotsakul D, Liggitt H, Chantratita N, Peacock S, et al. Pathogenicity of high-dose enteral inoculation of Burkholderia pseudomallei to mice. Am J Trop Med Hyg. 2010;83:1066-9 pubmed publisher
..Mice may shed bacteria in the stool for weeks after infection, and high titers of B. pseudomallei-specific IgG are detectable. This report of enteric murine melioidosis supports further consideration of this route of infection...