V P Werth

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint Failure of physiologic doses of pure UVA or UVB to induce lesions in photosensitive cutaneous lupus erythematosus: implications for phototesting
    Michele L Lokitz
    The University of Pennsylvania, Philadelphia, PA, USA
    Photodermatol Photoimmunol Photomed 22:290-6. 2006
  2. pmc Development of outcome measures for autoimmune dermatoses
    Elizabeth Gaines
    Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA
    Arch Dermatol Res 300:3-9. 2008
  3. doi request reprint Multicenter randomized, double-blind, placebo-controlled, clinical trial of dapsone as a glucocorticoid-sparing agent in maintenance-phase pemphigus vulgaris
    Victoria P Werth
    Department of Dermatology, University of Pennsylvania, 2 Rhodes Pavilion, 3600 Spruce St, Philadelphia, PA 19119, USA
    Arch Dermatol 144:25-32. 2008
  4. pmc Measurement of disease severity in cutaneous autoimmune diseases
    Cynthia Anyanwu
    Philadelphia VA Medical Center Philadelphia, PA Department of Dermatology, University of Pennsylvania School of Medicine Philadelphia, PA
    F1000Prime Rep 5:19. 2013
  5. pmc Gottron's papules exhibit dermal accumulation of CD44 variant 7 (CD44v7) and its binding partner osteopontin: a unique molecular signature
    Jessica S Kim
    New York University School of Medicine, New York, New York, USA
    J Invest Dermatol 132:1825-32. 2012
  6. pmc Tumor necrosis factor α release in peripheral blood mononuclear cells of cutaneous lupus and dermatomyositis patients
    Adam S Nabatian
    Philadelphia Veterans Affairs Medical Center, 38th and Woodland Avenues, Philadelphia, PA 08901, USA
    Arthritis Res Ther 14:R1. 2012
  7. pmc Impact of smoking in cutaneous lupus erythematosus
    Evan W Piette
    Philadelphia VA Medical Center, Philadelphia, PA, USA
    Arch Dermatol 148:317-22. 2012
  8. ncbi request reprint Photosensitivity in rheumatic diseases
    Victoria P Werth
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Investig Dermatol Symp Proc 9:57-63. 2004
  9. pmc Ultraviolet irradiation induces the accumulation of chondroitin sulfate, but not other glycosaminoglycans, in human skin
    Benjamin Boegel Werth
    Medical Research, Philadelphia Veterans Administration Medical Center, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 6:e14830. 2011
  10. ncbi request reprint Medical dermatology: a view to the future
    Victoria P Werth
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Invest Dermatol 126:528-9. 2006

Research Grants

Collaborators

Detail Information

Publications66

  1. ncbi request reprint Failure of physiologic doses of pure UVA or UVB to induce lesions in photosensitive cutaneous lupus erythematosus: implications for phototesting
    Michele L Lokitz
    The University of Pennsylvania, Philadelphia, PA, USA
    Photodermatol Photoimmunol Photomed 22:290-6. 2006
    ..Phototesting studies in cutaneous lupus erythematosus have yielded variable results, with most trials reporting photo-induction of lesions by both UVA and UVB in substantial numbers of patients...
  2. pmc Development of outcome measures for autoimmune dermatoses
    Elizabeth Gaines
    Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA
    Arch Dermatol Res 300:3-9. 2008
    ..Finally, this review more closely looks at CLE, DM, and PV and addresses the recent and ongoing progress that has been made in the development of their outcome measures...
  3. doi request reprint Multicenter randomized, double-blind, placebo-controlled, clinical trial of dapsone as a glucocorticoid-sparing agent in maintenance-phase pemphigus vulgaris
    Victoria P Werth
    Department of Dermatology, University of Pennsylvania, 2 Rhodes Pavilion, 3600 Spruce St, Philadelphia, PA 19119, USA
    Arch Dermatol 144:25-32. 2008
    ..To determine the efficacy of dapsone as a glucocorticoid-sparing agent in maintenance-phase pemphigus vulgaris (PV)...
  4. pmc Measurement of disease severity in cutaneous autoimmune diseases
    Cynthia Anyanwu
    Philadelphia VA Medical Center Philadelphia, PA Department of Dermatology, University of Pennsylvania School of Medicine Philadelphia, PA
    F1000Prime Rep 5:19. 2013
    ..Other challenges with the use of outcome measures include difficulties measuring change in mild disease, measuring response in topical studies, and capturing disease activity in skin with extensive post-inflammatory hyperpigmentation...
  5. pmc Gottron's papules exhibit dermal accumulation of CD44 variant 7 (CD44v7) and its binding partner osteopontin: a unique molecular signature
    Jessica S Kim
    New York University School of Medicine, New York, New York, USA
    J Invest Dermatol 132:1825-32. 2012
    ....
  6. pmc Tumor necrosis factor α release in peripheral blood mononuclear cells of cutaneous lupus and dermatomyositis patients
    Adam S Nabatian
    Philadelphia Veterans Affairs Medical Center, 38th and Woodland Avenues, Philadelphia, PA 08901, USA
    Arthritis Res Ther 14:R1. 2012
    ....
  7. pmc Impact of smoking in cutaneous lupus erythematosus
    Evan W Piette
    Philadelphia VA Medical Center, Philadelphia, PA, USA
    Arch Dermatol 148:317-22. 2012
    ..To investigate cigarette smoking in cutaneous lupus erythematosus (CLE)...
  8. ncbi request reprint Photosensitivity in rheumatic diseases
    Victoria P Werth
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Investig Dermatol Symp Proc 9:57-63. 2004
    ..In the presence of specific MHC class I and II genes, antigen-presenting cells initiate a primary immune response that leads to cutaneous, and likely systemic, autoimmune disease...
  9. pmc Ultraviolet irradiation induces the accumulation of chondroitin sulfate, but not other glycosaminoglycans, in human skin
    Benjamin Boegel Werth
    Medical Research, Philadelphia Veterans Administration Medical Center, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 6:e14830. 2011
    ..These molecules have important biologic functions and contribute to the cutaneous response to UV...
  10. ncbi request reprint Medical dermatology: a view to the future
    Victoria P Werth
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Invest Dermatol 126:528-9. 2006
  11. pmc Response to antimalarial agents in cutaneous lupus erythematosus: a prospective analysis
    Aileen Y Chang
    Philadelphia Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA
    Arch Dermatol 147:1261-7. 2011
    ..To demonstrate response to antimalarial agents in patients with cutaneous lupus erythematosus (CLE) using activity scores from the Cutaneous Lupus Erythematosus Disease Area and Severity Index, a validated outcome measure...
  12. pmc Development of the CLASI as a tool to measure disease severity and responsiveness to therapy in cutaneous lupus erythematosus
    Rachel Klein
    Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    Arch Dermatol 147:203-8. 2011
    ..To determine how to use the Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI) to classify patients according to disease severity (mild, moderate, and severe) and to identify which patients respond to therapy...
  13. ncbi request reprint Cutaneous lupus: insights into pathogenesis and disease classification
    Victoria P Werth
    The University of Pennsylvania and the Philadelphia Veterans Administration Hospital, Department of Dermatology 19104, USA
    Bull NYU Hosp Jt Dis 65:200-4. 2007
    ..Scientific efforts are beginning to clarify the pathophysiologic differences between subsets of cutaneous LE, but there are clearly many areas of investigation needed to elucidate the complex mechanisms that culminate in cutaneous LE...
  14. ncbi request reprint IL-12 completely blocks ultraviolet-induced secretion of tumor necrosis factor alpha from cultured skin fibroblasts and keratinocytes
    Victoria P Werth
    Department of Dermatology, University of Pennsylvania and Philadelphia V A Hospital, Philadelphia, Pennsylvania 19104, USA
    J Invest Dermatol 120:116-22. 2003
    ..Because tumor necrosis factor alpha is central to the pathogenesis of several photosensitive skin diseases and certain forms of immune suppression, interleukin-12 may have important physiologic, pathophysiologic, and therapeutic roles...
  15. ncbi request reprint Mannose binding lectin (MBL) polymorphisms associated with low MBL production in patients with dermatomyositis
    Victoria P Werth
    Philadelphia V A Medical Center Department of Dermatology Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, PA 19104, USA
    J Invest Dermatol 119:1394-9. 2002
    ..Our model is that genetic polymorphisms leading to overproduction of apoptotic keratinocytes and then impaired clearance of these cells contribute to the pathogenesis of adult dermatomyositis, a photoinduced autoimmune skin disease...
  16. ncbi request reprint Associations of tumor necrosis factor alpha and HLA polymorphisms with adult dermatomyositis: implications for a unique pathogenesis
    Victoria P Werth
    Philadelphia V A Medical Center, Department of Dermatology, University of Pennsylvania, USA
    J Invest Dermatol 119:617-20. 2002
    ..The differences in linkage with HLA-DR3, as well as several divergent clinical features, indicate that there are also fundamental mechanistic differences between dermatomyositis and subacute cutaneous lupus erythematosus...
  17. ncbi request reprint Association of a promoter polymorphism of tumor necrosis factor-alpha with subacute cutaneous lupus erythematosus and distinct photoregulation of transcription
    V P Werth
    The University of Pennsylvania, VA Hospital, Philadelphia, Pennsylvania, USA
    J Invest Dermatol 115:726-30. 2000
    ..Overall, our findings indicate a strong linkage between the -308A polymorphism and subacute systemic lupus erythematosus, which is likely to directly contribute to the photosensitivity of these patients...
  18. ncbi request reprint Wavelength-specific synergy between ultraviolet radiation and interleukin-1 alpha in the regulation of matrix-related genes: mechanistic role for tumor necrosis factor-alpha
    V P Werth
    Department of Dermatology, University of Pennsylvania, Philadelphia 19104, USA
    J Invest Dermatol 113:196-201. 1999
    ....
  19. ncbi request reprint Clinical manifestations of cutaneous lupus erythematosus
    Victoria P Werth
    Department of Dermatology, University of Pennsylvania, Philadelphia V A Hospital, 2 Rhoads Pavilion, 36th and Spruce Sts, Philadelphia, PA 19104, United States
    Autoimmun Rev 4:296-302. 2005
    ....
  20. ncbi request reprint Pathophysiology of cutaneous lupus erythematosus
    Julie H Lin
    Department of Dermatology, University of Pennsylvania, 2 Rhoads Pavilion, Philadelphia, PA 19104, USA
    Clin Rev Allergy Immunol 33:85-106. 2007
    ..In addition, we consider the role and importance of humoral and cellular factors, synthesizing the current understanding of the pathophysiology of cutaneous lupus...
  21. ncbi request reprint Dapsone as a glucocorticoid-sparing agent in maintenance-phase pemphigus vulgaris
    Michael R Heaphy
    Department of Dermatology, University of California San Francisco, San Francisco, CA, USA
    Arch Dermatol 141:699-702. 2005
    ..To determine the effect of dapsone on glucocorticoid-dependent patients with active or maintenance-phase pemphigus vulgaris...
  22. pmc Dermatomyositis
    M S Krathen
    Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA 19119, USA
    Curr Dir Autoimmun 10:313-32. 2008
    ..The seminal work regarding the pathogenesis of DM is reviewed and an update on the recent basic and molecular advances in the field is provided...
  23. doi request reprint TNF-alpha production in the skin
    M M Bashir
    Department of Dermatology, University of Pennsylvania, 2, Rhodes Pavilion, 3600 Spruce Street, Philadelphia, PA, 19104, USA
    Arch Dermatol Res 301:87-91. 2009
    ..Keratinocyte-derived TNF-alpha is a component of the early induction phase of the inflammatory cascade...
  24. pmc Modification of the cutaneous dermatomyositis disease area and severity index, an outcome instrument
    M Yassaee
    Veterans Affairs Medical Center, University of Pennsylvania, Philadelphia, PA 19104 2676, USA
    Br J Dermatol 162:669-73. 2010
    ..A scoring system of skin disease severity in dermatomyositis known as the Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI) has been developed...
  25. ncbi request reprint Lupus erythematosus induced by medications, ultraviolet radiation, and other exogenous agents: a review, with special focus on the development of subacute cutaneous lupus erythematosus in a genetically predisposed individual
    Michael Shapiro
    Department of Dermatology, University of Pennsylvania Health System, Philadelphia V A Hospital, Philadelphia, PA 19104, USA
    Int J Dermatol 43:87-94. 2004
    ..An environmental agent present in the barn, coupled with springtime ultraviolet light, likely triggered the disease in this immunogenetically susceptible individual...
  26. pmc The interferon-regulated gene signature is elevated in subacute cutaneous lupus erythematosus and discoid lupus erythematosus and correlates with the cutaneous lupus area and severity index score
    I Braunstein
    Dermatology Section, Philadelphia Veterans Affairs Medical Center, Philadelphia, PA 19104, USA
    Br J Dermatol 166:971-5. 2012
    ..Patients with SLE have increased IFN-regulated gene expression pointing towards a possible underlying genetic defect...
  27. ncbi request reprint Combination antimalarials in the treatment of cutaneous dermatomyositis: a retrospective study
    Gina Charlene Ang
    Department of Dermatology and Cutaneous Biology, Jefferson Medical College, Philadelphia, USA
    Arch Dermatol 141:855-9. 2005
    ....
  28. doi request reprint Update on morphea: part I. Epidemiology, clinical presentation, and pathogenesis
    Nicole Fett
    Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Am Acad Dermatol 64:217-28; quiz 229-30. 2011
    ..The underlying pathogenesis of morphea is incompletely understood at this time, but ultimately results in an imbalance of collagen production and destruction...
  29. doi request reprint Update on morphea: part II. Outcome measures and treatment
    Nicole Fett
    Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Am Acad Dermatol 64:231-42; quiz 243-4. 2011
    ..The most robust data in the treatment of morphea exists for methotrexate in combination with systemic steroids and ultraviolet A1...
  30. ncbi request reprint Lack of correlation of skin thickness with bone density in patients receiving chronic glucocorticoid
    V P Werth
    Department of Dermatology, University of Pennsylvania, Philadelphia 19104, USA
    Arch Dermatol Res 290:388-93. 1998
    ..The level of type I procollagen mRNA in skin from three GC-treated patients was 45% of the value in three age-matched controls. In conclusion, GCs cause statistically significant thinning of skin independently of the effects on bone...
  31. pmc Comparison of the reliability and validity of outcome instruments for cutaneous dermatomyositis
    R Q Klein
    Department of Dermatology, School of Medicine, University of Pennsylvania, 3600 Spruce Street, 2 Maloney Building, Philadelphia, PA 19104, USA
    Br J Dermatol 159:887-94. 2008
    ..Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI), Dermatomyositis Skin Severity Index (DSSI) and Cutaneous Assessment Tool (CAT) skin indices have been developed as outcome instruments...
  32. doi request reprint The Cutaneous Lupus Erythematosus Disease Activity and Severity Index: expansion for rheumatology and dermatology
    M S Krathen
    University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Arthritis Rheum 59:338-44. 2008
    ..To evaluate the validity of the Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI) for use by rheumatologists via reliability testing, and to extend the validation for dermatologists...
  33. pmc UVB and proinflammatory cytokines synergistically activate TNF-alpha production in keratinocytes through enhanced gene transcription
    Muhammad M Bashir
    Philadelphia V A Medical Center, Philadelphia, Pennsylvania 19104, USA
    J Invest Dermatol 129:994-1001. 2009
    ..UVB with IL-1alpha did not enhance the half-life of TNF-alpha mRNA over that seen with UVB alone. In conclusion, TNF-alpha expression in primary keratinocytes is upregulated transcriptionally by UVB and IL-1alpha...
  34. pmc Rheumatic manifestations of skin disease
    Jennie T Clarke
    Department of Dermatology, Penn State Hershey Medical Center, Hershey, USA
    Curr Opin Rheumatol 22:78-84. 2010
    ..Increasingly, studies are using the skin as a primary endpoint for evaluating therapies. This will review the current state of the art for the most common rheumatic skin diseases...
  35. ncbi request reprint Ultraviolet-B recruits mannose-binding lectin into skin from non-cutaneous sources
    Michele L Lokitz
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Invest Dermatol 125:166-73. 2005
    ..We hypothesize that MBL may facilitate non-inflammatory clearance of apoptotic debris in patients with photosensitive forms of DM...
  36. ncbi request reprint Skin involvement and outcome measures in systemic autoimmune diseases
    J Albrecht
    Department of Dermatology, University of Pennsylvania, Philadelphia, USA
    Clin Exp Rheumatol 24:S52-9. 2006
    ..The most typical skin manifestations are nodular lesions, which are commonly seen in BS and may be due to panniculitis [erythema nodosum (EN)-like lesions] or superficial thrombophlebitis...
  37. pmc The cutaneous lupus erythematosus disease area and severity index: a responsive instrument to measure activity and damage in patients with cutaneous lupus erythematosus
    Zuleika L Bonilla-Martinez
    Department of Dermatology, University of Pennsylvania, 2 Rhodes Pavilion, 3600 Spruce St, Philadelphia, PA 19119, USA
    Arch Dermatol 144:173-80. 2008
    ..To assess the clinical responsiveness of the CLASI (Cutaneous Lupus Erythematosus [CLE] Disease Area and Severity Index)...
  38. pmc Tumor necrosis factor inhibitor-associated dermatomyositis
    Rachel Klein
    Department of Medicine, Division of Rheumatology, University of Pennsylvania School of Medicine, Perelman Center for Advanced Medicine, First Floor South Pavilion, 3400 Civic Center Blvd, Philadelphia, PA 19104, USA
    Arch Dermatol 146:780-4. 2010
    ..Their symptoms persisted after discontinuation of the treatment with the TNF inhibitors but responded to treatment with corticosteroids and immunosuppressive medications...
  39. pmc Interstitial lung disease in classic and skin-predominant dermatomyositis: a retrospective study with screening recommendations
    Pamela A Morganroth
    Department of Dermatology, Hospital of the University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA 19104, USA
    Arch Dermatol 146:729-38. 2010
    ..2) To compare the pulmonary abnormalities of patients with classic dermatomyositis and those with skin-predominant dermatomyositis...
  40. pmc Reliability and convergent validity of two outcome instruments for pemphigus
    Misha Rosenbach
    Department of Dermatology, University of Pennsylvania, Philadelphia, PA 19119, USA
    J Invest Dermatol 129:2404-10. 2009
    ..Subset analysis suggests that for this population of mild-to-moderate disease activity, the PDAI captures more variability in cutaneous disease than the ABSIS...
  41. doi request reprint The impact of skin damage due to cutaneous lupus on quality of life
    S M Verma
    Department of Dermatology, Philadelphia Veterans Affairs Medical Center, Philadelphia, PA, U S A Department of Dermatology, University of Pennsylvania, Philadelphia, PA, U S A
    Br J Dermatol 170:315-21. 2014
    ..Racial and ethnic disparities have been reported in disease activity and outcomes in systemic lupus erythematosus, but similar information is not available for CLE...
  42. pmc A multicentre, cross-sectional study on quality of life in patients with cutaneous lupus erythematosus
    R Vasquez
    Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Br J Dermatol 168:145-53. 2013
    ..Whether patients with CLE in other geographic locations have similar quality of life is unknown...
  43. ncbi request reprint Papulosquamous disorders of the elderly
    A van Voorhees
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Clin Geriatr Med 17:739-68, vii. 2001
    ..Treatment often involves identifying underlying systemic causes, as well as specific approaches based on the diagnosis and severity of clinical presentation...
  44. ncbi request reprint Preserving medical dermatology. A colleague lost, a call to arms, and a plan for battle
    V P Werth
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Dermatol Clin 19:583-92. 2001
    ..Without an steady stream of young clinician-investigators focused on the many challenging problems in medical dermatology, dermatology will not exist as the specialty it is today...
  45. pmc Cutaneous lupus and the Cutaneous Lupus Erythematosus Disease Area and Severity Index instrument
    Rachel S Klein
    Philadelphia VA Medical Center, Philadelphia, PA, USA
    Rheum Dis Clin North Am 36:33-51, vii. 2010
    ..It also describes the Cutaneous Lupus Erythematosus Disease Area and Severity Index, a novel clinical outcome instrument that quantifies cutaneous activity and damage in cutaneous lupus erythematosus...
  46. ncbi request reprint Multicentric reticulohistiocytosis presenting with clinical features of dermatomyositis
    Sherry H Hsiung
    Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Am Acad Dermatol 48:S11-4. 2003
    ..Thus, it is important to consider the possibility of multicentric reticulohistiocytosis when evaluating a patient with the clinical diagnosis of dermatomyositis...
  47. ncbi request reprint Modification to the approach of the diagnosis of mucous membrane pemphigoid: A case report and literature review
    Ernesta Parisi
    University of Pennsylvania, Department of Oral Medicine, Philadelphia, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95:182-6. 2003
    ..This case report illustrates a case of antiepiligrin MMP in a patient with an advanced cancer of the bladder...
  48. pmc The CLASI (Cutaneous Lupus Erythematosus Disease Area and Severity Index): an outcome instrument for cutaneous lupus erythematosus
    Joerg Albrecht
    Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Invest Dermatol 125:889-94. 2005
    ..96 (95% CI = 0.89 to 1.00) and for the damage score Sp was 0.99 (95% CI = 0.97-1.00). Clinical responsiveness needs to be evaluated in a prospective clinical trial, which is ongoing...
  49. ncbi request reprint Number, characteristics, and classification of patients with dermatomyositis seen by dermatology and rheumatology departments at a large tertiary medical center
    Rhonda Q Klein
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Am Acad Dermatol 57:937-43. 2007
    ..The current diagnostic criteria for dermatomyositis (DM) exclude patients without muscle involvement. As a result there is a paucity of research related to the complete spectrum of the disease...
  50. pmc The risk of ultraviolet radiation exposure from indoor lamps in lupus erythematosus
    Rachel S Klein
    Philadelphia V A Hospital, Philadelphia, PA 19104, United States
    Autoimmun Rev 8:320-4. 2009
    ..Therefore, it is possible that this chronic exposure could ultimately result in a significant accumulation of damage...
  51. pmc Analysis of compact fluorescent lights for use by patients with photosensitive conditions
    Rachel S Klein
    Philadelphia V A Hospital, and Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA
    Photochem Photobiol 85:1004-10. 2009
    ..01 to 15 mJ cm(-2). Because patients are exposed continually over long time frames, this could lead to significant cumulative damage. It would therefore be prudent for patients to use bulbs with the lowest UV irradiance...
  52. ncbi request reprint Thalidomide in cutaneous lupus erythematosus
    Michelle T Pelle
    Department of Dermatology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Am J Clin Dermatol 4:379-87. 2003
    ..With appropriate control of drug access and close physician monitoring, thalidomide provides a needed therapeutic option for the treatment of refractory cases of cutaneous lupus erythematosus...
  53. pmc Cross-sectional analysis of a collaborative Web-based database for lupus erythematosus-associated skin lesions: prospective enrollment of 114 patients
    Siamak Moghadam-Kia
    Department of Dermatology, University of Pennsylvania, Philadelphia, PA 19104 4283, USA
    Arch Dermatol 145:255-60. 2009
    ....
  54. ncbi request reprint Nephrogenic fibrosing dermopathy/nephrogenic systemic fibrosis: a case series of nine patients and review of the literature
    Camille E Introcaso
    Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Int J Dermatol 46:447-52. 2007
    ..The only common exposure amongst patients is acute or chronic renal failure. The pathophysiology of the disease remains to be elucidated, and there is currently no consistently effective treatment for this unremitting disease...
  55. ncbi request reprint Pemphigus: a treatment update
    Sarah E Dick
    Department of Dermatology, Philadelphia VA Medical Center, University of Pennsylvania, Philadelphia, PA, USA
    Autoimmunity 39:591-9. 2006
    ..Here we review the available treatment options and novel therapies for pemphigus and the supporting data...
  56. ncbi request reprint Skin disorders with arthritis
    Joshua Levin
    Department of Dermatology, University of Pennsylvania, PA 19104, USA
    Best Pract Res Clin Rheumatol 20:809-26. 2006
    ..This review will discuss the clinical presentation, both cutaneous and musculoskeletal, diagnosis and management of these disorders...
  57. ncbi request reprint Cutaneous Mycobacterium haemophilum infection in iatrogenically immunocompromised patients without transplantation
    Jason P Lott
    Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Am Acad Dermatol 59:139-42. 2008
    ..haemophilum may arise in this patient population. Accordingly, we emphasize that a high index of suspicion is needed for diagnosis, which ultimately relies on skin biopsy, histopathologic examination, and culture...
  58. pmc Mycophenolate mofetil for interstitial lung disease in dermatomyositis
    Pamela A Morganroth
    Philadelphia VA Medical Center, University of Pennsylvania, USA
    Arthritis Care Res (Hoboken) 62:1496-501. 2010
    ..To report our experience using mycophenolate mofetil as first-line treatment for dermatomyositis-associated interstitial lung disease...
  59. ncbi request reprint Management of cutaneous dermatomyositis: current therapeutic options
    Rhonda D Quain
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Am J Clin Dermatol 7:341-51. 2006
    ....
  60. ncbi request reprint Darier's disease associated with an underlying neoplasm in combination with a nodular fibroproliferative disease
    Kathryn L Dortzbach
    Department of Dermatology, The Hospital of the University of Pennsylvania, Philadelphia 19104, USA
    J Am Acad Dermatol 49:S237-9. 2003
    ..We describe a 74-year-old man with metastatic carcinoma in whom fibroproliferative disease and an acquired variant of Darier's disease developed, both of which may have been paraneoplastic processes...
  61. pmc Quality of life and disease severity in a cutaneous lupus erythematosus pilot study
    Elizabeth Gaines
    Arch Dermatol 144:1061-2. 2008
  62. ncbi request reprint Improvement in dermatomyositis rash associated with the use of antiestrogen medication
    Danya Sereda
    Section of Dermatology, Universite de Montreal
    Arch Dermatol 142:70-2. 2006
    ..Recently, reports supporting a role for anti-tumor necrosis factor alpha (TNF-alpha) therapy in the treatment of DM have emerged...
  63. ncbi request reprint Activation of autoimmunity following use of immunostimulatory herbal supplements
    Alice N Lee
    Section of Dermatology, University of Chicago, IL, USA
    Arch Dermatol 140:723-7. 2004
    ..Although this explains their beneficial effects in preventing or curtailing disease, to our knowledge, no immunostimulatory herbal supplements have been reported to exacerbate disorders of immune system overactivity...
  64. ncbi request reprint Development of the CLASI as an outcome instrument for cutaneous lupus erythematosus
    Joerg Albrecht
    Department of Medicine, Division of Dermatology, John Stroger Jr Hospital of Cook County, Chicago, Illinois, USA
    Dermatol Ther 20:93-101. 2007
    ....
  65. pmc Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus
    Dedee F Murrell
    Department of Dermatology at St George Hospital, University of NSW, Sydney, Australia
    J Am Acad Dermatol 58:1043-6. 2008
    ..These should assist in development of consistent reporting of outcomes in future studies...
  66. pmc The cutaneous lupus disease activity and severity index as a validated outcome measure for cutaneous lupus erythematosus: comment on the article by Stamm et al
    Michael Krathen
    Arthritis Rheum 59:601-2. 2008

Research Grants2

  1. PATIENT-ORIENTED RESEARCH IN SKIN AUTOMMUNE DISEASE
    Victoria Werth; Fiscal Year: 2005
    ..This K24 translational grant is intended to permit the P.I. greater time to focus on patient-based scientific studies and will provide an infrastructure for Dr. Werth to pursue and mentor in POR. ..