Frank Werblin

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Crossover inhibition in the retina: circuitry that compensates for nonlinear rectifying synaptic transmission
    Alyosha Molnar
    School of Electrical and Computer Engineering ECE, Cornell University, Ithaca, NY 14853, USA
    J Comput Neurosci 27:569-90. 2009
  2. pmc Six different roles for crossover inhibition in the retina: correcting the nonlinearities of synaptic transmission
    Frank S Werblin
    Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA
    Vis Neurosci 27:1-8. 2010
  3. ncbi request reprint Inhibitory feedback shapes bipolar cell responses in the rabbit retina
    Alyosha Molnar
    Department of Electrical Engineering and Computer Science, University of California Berkeley, Berkeley, CA 94720, USA
    J Neurophysiol 98:3423-35. 2007
  4. doi request reprint Differential targeting of optical neuromodulators to ganglion cell soma and dendrites allows dynamic control of center-surround antagonism
    Kenneth P Greenberg
    Department of Molecular and Cell Biology, Division of Neurobiology, University of California, Berkeley, Berkeley, CA 94720 3200, USA
    Neuron 69:713-20. 2011
  5. ncbi request reprint Rapid global shifts in natural scenes block spiking in specific ganglion cell types
    Botond Roska
    Department of Molecular and Cell Biology, University of California Berkeley, 145 LSA, California 94720, USA
    Nat Neurosci 6:600-8. 2003
  6. ncbi request reprint The movies in our eyes
    Frank Werblin
    University of California, Berkeley, USA
    Sci Am 296:72-9. 2007
  7. pmc Retinal synaptic pathways underlying the response of the rabbit local edge detector
    Thomas L Russell
    Division of Neurobiology, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720 3200, USA
    J Neurophysiol 103:2757-69. 2010
  8. pmc Three forms of spatial temporal feedforward inhibition are common to different ganglion cell types in rabbit retina
    Xin Chen
    Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA
    J Neurophysiol 103:2618-32. 2010
  9. ncbi request reprint Mechanisms and circuitry underlying directional selectivity in the retina
    Shelley I Fried
    Vision Science, University of California Berkeley, 145 LSA, Berkeley, California 94720, USA
    Nature 420:411-4. 2002
  10. ncbi request reprint Parallel processing in retinal ganglion cells: how integration of space-time patterns of excitation and inhibition form the spiking output
    Botond Roska
    Department of Molecular and Cell Biology, University of California at Berkeley, 94720, USA
    J Neurophysiol 95:3810-22. 2006

Research Grants

  1. DYNAMIC PATTERN ANALYSIS OF RETINAL FUNCTION
    Frank Werblin; Fiscal Year: 2000
  2. DYNAMIC PATTERN ANALYSIS OF RETINAL FUNCTION
    Frank Werblin; Fiscal Year: 2002
  3. MEMBRANE MECHANISMS MEDIATING RETINAL FUNCTION
    Frank Werblin; Fiscal Year: 1980
  4. NEUROMODULATORY PATHWAYS IN THE RETINA
    Frank Werblin; Fiscal Year: 1990
  5. Push-pull Interactions Between ON and OFF Bipolar, Amacrine and Ganglion cells
    Frank S Werblin; Fiscal Year: 2010
  6. Amacrine Cell Circuitry Mediating Visual Function
    Frank Werblin; Fiscal Year: 2005
  7. NEUROMODULATORY PATHWAYS IN THE RETINA
    Frank Werblin; Fiscal Year: 1992
  8. Amacrine Cell Circuitry Mediating Visual Function
    Frank Werblin; Fiscal Year: 2006
  9. Amacrine Cell Circuitry Mediating Visual Function
    Frank Werblin; Fiscal Year: 2007
  10. DYNAMIC PATTERN ANALYSIS OF RETINAL FUNCTION
    Frank Werblin; Fiscal Year: 1999

Collaborators

Detail Information

Publications12

  1. pmc Crossover inhibition in the retina: circuitry that compensates for nonlinear rectifying synaptic transmission
    Alyosha Molnar
    School of Electrical and Computer Engineering ECE, Cornell University, Ithaca, NY 14853, USA
    J Comput Neurosci 27:569-90. 2009
    ..A similar circuit motif is employed in the electronics industry to compensate for transistor nonlinearities in analog circuits...
  2. pmc Six different roles for crossover inhibition in the retina: correcting the nonlinearities of synaptic transmission
    Frank S Werblin
    Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA
    Vis Neurosci 27:1-8. 2010
    ..In some cases, crossover extends the operating range of cone-driven OFF ganglion cells into the scotopic levels. Crossover inhibition is also found in neurons of the lateral geniculate nucleus and V1...
  3. ncbi request reprint Inhibitory feedback shapes bipolar cell responses in the rabbit retina
    Alyosha Molnar
    Department of Electrical Engineering and Computer Science, University of California Berkeley, Berkeley, CA 94720, USA
    J Neurophysiol 98:3423-35. 2007
    ..Thus morphologically diverse bipolar cells receive only four main types of inhibitory input, and the majority of "inhibitory" inputs actually serve to enhance excitation...
  4. doi request reprint Differential targeting of optical neuromodulators to ganglion cell soma and dendrites allows dynamic control of center-surround antagonism
    Kenneth P Greenberg
    Department of Molecular and Cell Biology, Division of Neurobiology, University of California, Berkeley, Berkeley, CA 94720 3200, USA
    Neuron 69:713-20. 2011
    ..This approach bypasses the degenerated areas of the distal retina and could provide a first step in restoring sight to individuals suffering from retinal disease...
  5. ncbi request reprint Rapid global shifts in natural scenes block spiking in specific ganglion cell types
    Botond Roska
    Department of Molecular and Cell Biology, University of California Berkeley, 145 LSA, California 94720, USA
    Nat Neurosci 6:600-8. 2003
    ..These findings indicate that the fast, transient elevation of visual threshold during rapid shifts in scene has a significant retinal component...
  6. ncbi request reprint The movies in our eyes
    Frank Werblin
    University of California, Berkeley, USA
    Sci Am 296:72-9. 2007
  7. pmc Retinal synaptic pathways underlying the response of the rabbit local edge detector
    Thomas L Russell
    Division of Neurobiology, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720 3200, USA
    J Neurophysiol 103:2757-69. 2010
    ....
  8. pmc Three forms of spatial temporal feedforward inhibition are common to different ganglion cell types in rabbit retina
    Xin Chen
    Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA
    J Neurophysiol 103:2618-32. 2010
    ..Similar subunits likely exist in the circuits of other ganglion cell types as well...
  9. ncbi request reprint Mechanisms and circuitry underlying directional selectivity in the retina
    Shelley I Fried
    Vision Science, University of California Berkeley, 145 LSA, Berkeley, California 94720, USA
    Nature 420:411-4. 2002
    ..The interplay of these components generates reduced excitation and enhanced inhibition in the null direction, thereby ensuring robust directional selectivity...
  10. ncbi request reprint Parallel processing in retinal ganglion cells: how integration of space-time patterns of excitation and inhibition form the spiking output
    Botond Roska
    Department of Molecular and Cell Biology, University of California at Berkeley, 94720, USA
    J Neurophysiol 95:3810-22. 2006
    ..They reveal a surprising synergistic interaction between excitation and inhibition in most ganglion cells...
  11. ncbi request reprint Directional selectivity is formed at multiple levels by laterally offset inhibition in the rabbit retina
    Shelley I Fried
    Vision Science, University of California at Berkeley, 145 LSA, Berkeley, California 94720, USA
    Neuron 46:117-27. 2005
    ..Cholinergic pathways from outside the dendritic field reach both ON and OFF dendrites, but both of these pathways are normally inactivated by GABAergic synapses...
  12. doi request reprint Amacrine-to-amacrine cell inhibition in the rabbit retina
    Hain Ann Hsueh
    Department of Bioengineering, University of California at Berkeley, Berkeley, CA 94720, USA
    J Neurophysiol 100:2077-88. 2008
    ..Although the morphology of amacrine cells is diverse, the interactions between excitation and inhibition appear to be relatively limited and specific...

Research Grants34

  1. DYNAMIC PATTERN ANALYSIS OF RETINAL FUNCTION
    Frank Werblin; Fiscal Year: 2000
    ..Analyses of these data will yield insights into the underlying neural mechanisms that mediate visual function and provide some clues about the strategies undertaken via neuronal interactions at each retinal level. ..
  2. DYNAMIC PATTERN ANALYSIS OF RETINAL FUNCTION
    Frank Werblin; Fiscal Year: 2002
    ..Analyses of these data will yield insights into the underlying neural mechanisms that mediate visual function and provide some clues about the strategies undertaken via neuronal interactions at each retinal level. ..
  3. MEMBRANE MECHANISMS MEDIATING RETINAL FUNCTION
    Frank Werblin; Fiscal Year: 1980
    ..The new techniques liberate the retina from constraints imposed upon the traditional eyecup preparation, and allow detailed neurobiological studies in this intriguing but difficult preparation. ..
  4. NEUROMODULATORY PATHWAYS IN THE RETINA
    Frank Werblin; Fiscal Year: 1990
    ..Thus it may be possible to provide a link between retinal function (or dysfunction) and pharmacological intervention...
  5. Push-pull Interactions Between ON and OFF Bipolar, Amacrine and Ganglion cells
    Frank S Werblin; Fiscal Year: 2010
    ....
  6. Amacrine Cell Circuitry Mediating Visual Function
    Frank Werblin; Fiscal Year: 2005
    ..Through this correlation process we hope to be able to describe the role of specific amacrine cells in generating different components of visual function. ..
  7. NEUROMODULATORY PATHWAYS IN THE RETINA
    Frank Werblin; Fiscal Year: 1992
    ..Thus it may be possible to provide a link between retinal function (or dysfunction) and pharmacological intervention...
  8. Amacrine Cell Circuitry Mediating Visual Function
    Frank Werblin; Fiscal Year: 2006
    ..Through this correlation process we hope to be able to describe the role of specific amacrine cells in generating different components of visual function. ..
  9. Amacrine Cell Circuitry Mediating Visual Function
    Frank Werblin; Fiscal Year: 2007
    ..Through this correlation process we hope to be able to describe the role of specific amacrine cells in generating different components of visual function. ..
  10. DYNAMIC PATTERN ANALYSIS OF RETINAL FUNCTION
    Frank Werblin; Fiscal Year: 1999
    ..Analyses of these data will yield insights into the underlying neural mechanisms that mediate visual function and provide some clues about the strategies undertaken via neuronal interactions at each retinal level. ..
  11. Push-pull Interactions Between ON and OFF Bipolar, Amacrine and Ganglion cells
    Frank Werblin; Fiscal Year: 2009
    ....
  12. DYNAMIC PATTERN ANALYSIS OF RETINAL FUNCTION
    Frank Werblin; Fiscal Year: 2003
    ..Analyses of these data will yield insights into the underlying neural mechanisms that mediate visual function and provide some clues about the strategies undertaken via neuronal interactions at each retinal level. ..
  13. DYNAMIC PATTERN ANALYSIS OF RETINAL FUNCTION
    Frank Werblin; Fiscal Year: 2001
    ..Analyses of these data will yield insights into the underlying neural mechanisms that mediate visual function and provide some clues about the strategies undertaken via neuronal interactions at each retinal level. ..
  14. NEUROMODULATORY PATHWAYS IN THE RETINA
    Frank Werblin; Fiscal Year: 1991
    ..Thus it may be possible to provide a link between retinal function (or dysfunction) and pharmacological intervention...
  15. NEUROMODULATORY PATHWAYS IN THE RETINA
    Frank Werblin; Fiscal Year: 1993
    ..Thus it may be possible to provide a link between retinal function (or dysfunction) and pharmacological intervention...
  16. Push-pull Interactions Between ON and OFF Bipolar, Amacrine and Ganglion cells
    Frank S Werblin; Fiscal Year: 2011
    ....