Research Topics
| Frank WerblinSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Crossover inhibition in the retina: circuitry that compensates for nonlinear rectifying synaptic transmissionAlyosha Molnar
School of Electrical and Computer Engineering ECE, Cornell University, Ithaca, NY 14853, USA
J Comput Neurosci 27:569-90. 2009..A similar circuit motif is employed in the electronics industry to compensate for transistor nonlinearities in analog circuits...- Six different roles for crossover inhibition in the retina: correcting the nonlinearities of synaptic transmissionFrank S Werblin
Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA
Vis Neurosci 27:1-8. 2010..In some cases, crossover extends the operating range of cone-driven OFF ganglion cells into the scotopic levels. Crossover inhibition is also found in neurons of the lateral geniculate nucleus and V1... 
Inhibitory feedback shapes bipolar cell responses in the rabbit retinaAlyosha Molnar
Department of Electrical Engineering and Computer Science, University of California Berkeley, Berkeley, CA 94720, USA
J Neurophysiol 98:3423-35. 2007..Thus morphologically diverse bipolar cells receive only four main types of inhibitory input, and the majority of "inhibitory" inputs actually serve to enhance excitation...
Differential targeting of optical neuromodulators to ganglion cell soma and dendrites allows dynamic control of center-surround antagonismKenneth P Greenberg
Department of Molecular and Cell Biology, Division of Neurobiology, University of California, Berkeley, Berkeley, CA 94720 3200, USA
Neuron 69:713-20. 2011..This approach bypasses the degenerated areas of the distal retina and could provide a first step in restoring sight to individuals suffering from retinal disease...- The movies in our eyesFrank Werblin
University of California, Berkeley, USA
Sci Am 296:72-9. 2007 - Rapid global shifts in natural scenes block spiking in specific ganglion cell typesBotond Roska
Department of Molecular and Cell Biology, University of California Berkeley, 145 LSA, California 94720, USA
Nat Neurosci 6:600-8. 2003..These findings indicate that the fast, transient elevation of visual threshold during rapid shifts in scene has a significant retinal component... - Retinal synaptic pathways underlying the response of the rabbit local edge detectorThomas L Russell
Division of Neurobiology, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720 3200, USA
J Neurophysiol 103:2757-69. 2010.... - Three forms of spatial temporal feedforward inhibition are common to different ganglion cell types in rabbit retinaXin Chen
Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA
J Neurophysiol 103:2618-32. 2010..Similar subunits likely exist in the circuits of other ganglion cell types as well... - Mechanisms and circuitry underlying directional selectivity in the retinaShelley I Fried
Vision Science, University of California Berkeley, 145 LSA, Berkeley, California 94720, USA
Nature 420:411-4. 2002..The interplay of these components generates reduced excitation and enhanced inhibition in the null direction, thereby ensuring robust directional selectivity... - Parallel processing in retinal ganglion cells: how integration of space-time patterns of excitation and inhibition form the spiking outputBotond Roska
Department of Molecular and Cell Biology, University of California at Berkeley, 94720, USA
J Neurophysiol 95:3810-22. 2006..They reveal a surprising synergistic interaction between excitation and inhibition in most ganglion cells... - Directional selectivity is formed at multiple levels by laterally offset inhibition in the rabbit retinaShelley I Fried
Vision Science, University of California at Berkeley, 145 LSA, Berkeley, California 94720, USA
Neuron 46:117-27. 2005..Cholinergic pathways from outside the dendritic field reach both ON and OFF dendrites, but both of these pathways are normally inactivated by GABAergic synapses... - Amacrine-to-amacrine cell inhibition in the rabbit retinaHain Ann Hsueh
Department of Bioengineering, University of California at Berkeley, Berkeley, CA 94720, USA
J Neurophysiol 100:2077-88. 2008..Although the morphology of amacrine cells is diverse, the interactions between excitation and inhibition appear to be relatively limited and specific...
Research Grants
- DYNAMIC PATTERN ANALYSIS OF RETINAL FUNCTIONFrank Werblin; Fiscal Year: 2003..Analyses of these data will yield insights into the underlying neural mechanisms that mediate visual function and provide some clues about the strategies undertaken via neuronal interactions at each retinal level. ..
- Amacrine Cell Circuitry Mediating Visual FunctionFrank Werblin; Fiscal Year: 2007..Through this correlation process we hope to be able to describe the role of specific amacrine cells in generating different components of visual function. ..
- Push-pull Interactions Between ON and OFF Bipolar, Amacrine and Ganglion cellsFrank S Werblin; Fiscal Year: 2010....
- MEMBRANE MECHANISMS MEDIATING RETINAL FUNCTIONFrank Werblin; Fiscal Year: 1980..The new techniques liberate the retina from constraints imposed upon the traditional eyecup preparation, and allow detailed neurobiological studies in this intriguing but difficult preparation. ..
- NEUROMODULATORY PATHWAYS IN THE RETINAFrank Werblin; Fiscal Year: 1993..Thus it may be possible to provide a link between retinal function (or dysfunction) and pharmacological intervention...
- Push-pull Interactions Between ON and OFF Bipolar, Amacrine and Ganglion cellsFrank S Werblin; Fiscal Year: 2011....