Jonathan F Wenk

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Numerical modeling of stress in stenotic arteries with microcalcifications: a parameter sensitivity study
    Jonathan F Wenk
    Department of Bioengineering, University of California San Francisco, CA 94121, USA
    J Biomech Eng 133:014503. 2011
  2. pmc Regional left ventricular myocardial contractility and stress in a finite element model of posterobasal myocardial infarction
    Jonathan F Wenk
    Department of Surgery, University of California San Francisco, CA 94121, USA
    J Biomech Eng 133:044501. 2011
  3. doi request reprint Numerical modeling of stress in stenotic arteries with microcalcifications: a micromechanical approximation
    Jonathan F Wenk
    Department of Mechanical Engineering, University of California Berkeley, CA 94720 1740, USA
    J Biomech Eng 132:091011. 2010
  4. doi request reprint Viscoelastic and biomechanical properties of osteochondral tissue constructs generated from graded polycaprolactone and beta-tricalcium phosphate composites
    Cevat Erisken
    Stevens Institute of Technology, Hoboken, NJ 07030, USA
    J Biomech Eng 132:091013. 2010
  5. pmc Dor procedure for dyskinetic anteroapical myocardial infarction fails to improve contractility in the border zone
    Kay Sun
    Department of Surgery, University of California, San Francisco, Calif, USA
    J Thorac Cardiovasc Surg 140:233-9, 239.e1-4. 2010
  6. pmc Biventricular finite element modeling of the Acorn CorCap Cardiac Support Device on a failing heart
    Jonathan F Wenk
    Department of Mechanical Engineering, University of Kentucky, Lexington, Kentucky, USA
    Ann Thorac Surg 95:2022-7. 2013
  7. pmc The effect of mitral annuloplasty shape in ischemic mitral regurgitation: a finite element simulation
    Vincent M Wong
    Department of Surgery, University of California, San Francisco, San Francisco, CA 94121, USA
    Ann Thorac Surg 93:776-82. 2012
  8. pmc Analysis of patient-specific surgical ventricular restoration: importance of an ellipsoidal left ventricular geometry for diastolic and systolic function
    Lik Chuan Lee
    Department of Surgery, University of California, San Francisco, California, USA
    J Appl Physiol (1985) 115:136-44. 2013
  9. pmc Left ventricular myocardial contractility is depressed in the borderzone after posterolateral myocardial infarction
    Rafael Shimkunas
    Department of Medicine, University of California, San Francisco, CA 94121, USA
    Ann Thorac Surg 95:1619-25. 2013
  10. pmc First evidence of depressed contractility in the border zone of a human myocardial infarction
    Jonathan F Wenk
    Department of Mechanical Engineering, University of Kentucky, Lexington, Kentucky, USA
    Ann Thorac Surg 93:1188-93. 2012

Collaborators

Detail Information

Publications15

  1. doi request reprint Numerical modeling of stress in stenotic arteries with microcalcifications: a parameter sensitivity study
    Jonathan F Wenk
    Department of Bioengineering, University of California San Francisco, CA 94121, USA
    J Biomech Eng 133:014503. 2011
    ..Biomech. Eng., 132, p. 091011), which indicates that the maximum circumferential stress always shifts to the region of microcalcification...
  2. pmc Regional left ventricular myocardial contractility and stress in a finite element model of posterobasal myocardial infarction
    Jonathan F Wenk
    Department of Surgery, University of California San Francisco, CA 94121, USA
    J Biomech Eng 133:044501. 2011
    ..The myofiber stress in the BZ was found to be elevated, relative to the remote region. This could cause further damage to the contracting myocytes, leading to heart failure...
  3. doi request reprint Numerical modeling of stress in stenotic arteries with microcalcifications: a micromechanical approximation
    Jonathan F Wenk
    Department of Mechanical Engineering, University of California Berkeley, CA 94720 1740, USA
    J Biomech Eng 132:091011. 2010
    ..This is a possible explanation of why 40% of plaque ruptures occur away from the shoulder region of the cap...
  4. doi request reprint Viscoelastic and biomechanical properties of osteochondral tissue constructs generated from graded polycaprolactone and beta-tricalcium phosphate composites
    Cevat Erisken
    Stevens Institute of Technology, Hoboken, NJ 07030, USA
    J Biomech Eng 132:091013. 2010
    ..These experimental findings suggest that viscoelastic material functions of the tissue constructs can provide valuable inputs for the stages of in vitro tissue development...
  5. pmc Dor procedure for dyskinetic anteroapical myocardial infarction fails to improve contractility in the border zone
    Kay Sun
    Department of Surgery, University of California, San Francisco, Calif, USA
    J Thorac Cardiovasc Surg 140:233-9, 239.e1-4. 2010
    ..Endoventricular patch plasty (Dor) is used to reduce left ventricular volume after myocardial infarction and subsequent left ventricular remodeling...
  6. pmc Biventricular finite element modeling of the Acorn CorCap Cardiac Support Device on a failing heart
    Jonathan F Wenk
    Department of Mechanical Engineering, University of Kentucky, Lexington, Kentucky, USA
    Ann Thorac Surg 95:2022-7. 2013
    ..However, the effects of the Acorn CSD on myofiber stress and ventricular function remain unknown. We tested the hypothesis that the Acorn CSD reduces end-diastolic (ED) myofiber stress...
  7. pmc The effect of mitral annuloplasty shape in ischemic mitral regurgitation: a finite element simulation
    Vincent M Wong
    Department of Surgery, University of California, San Francisco, San Francisco, CA 94121, USA
    Ann Thorac Surg 93:776-82. 2012
    ..Undersized mitral annuloplasty (MA) is the preferred surgical treatment for chronic ischemic mitral regurgitation. However, the preferred shape of undersized MA is unclear...
  8. pmc Analysis of patient-specific surgical ventricular restoration: importance of an ellipsoidal left ventricular geometry for diastolic and systolic function
    Lik Chuan Lee
    Department of Surgery, University of California, San Francisco, California, USA
    J Appl Physiol (1985) 115:136-44. 2013
    ....
  9. pmc Left ventricular myocardial contractility is depressed in the borderzone after posterolateral myocardial infarction
    Rafael Shimkunas
    Department of Medicine, University of California, San Francisco, CA 94121, USA
    Ann Thorac Surg 95:1619-25. 2013
    ..Contractility in the borderzone (BZ) after anteroapical myocardial infarction (MI) is depressed. We tested the hypothesis that BZ contractility is also decreased after posterolateral MI...
  10. pmc First evidence of depressed contractility in the border zone of a human myocardial infarction
    Jonathan F Wenk
    Department of Mechanical Engineering, University of Kentucky, Lexington, Kentucky, USA
    Ann Thorac Surg 93:1188-93. 2012
    ..We sought, for the first time, to document the presence of impaired contractility of the myofibers in the human BZ myocardium...
  11. pmc First finite element model of the left ventricle with mitral valve: insights into ischemic mitral regurgitation
    Jonathan F Wenk
    Department of Surgery, University of California, San Francisco, California, USA
    Ann Thorac Surg 89:1546-53. 2010
    ..Left ventricular remodeling after posterobasal myocardial infarction can lead to ischemic mitral regurgitation. This occurs as a consequence of leaflet tethering due to posterior papillary muscle displacement...
  12. pmc A novel method for quantifying the in-vivo mechanical effect of material injected into a myocardial infarction
    Jonathan F Wenk
    Department of Surgery, University of California, San Francisco, Department of Veterans Affairs Medical Center, San Francisco, California 94121, USA
    Ann Thorac Surg 92:935-41. 2011
    ..We sought to quantify the effects of injecting a calcium hydroxyapatite-based tissue filler on the passive material response of infarcted left ventricles...
  13. pmc Material properties of CorCap passive cardiac support device
    Sam Chitsaz
    Department of Surgery, University of California at San Francisco and San Francisco Veterans Affairs Medical Center, San Francisco, California, USA
    Ann Thorac Surg 95:148-54. 2013
    ..However, as an open mesh surrounding the heart, it is unknown what the mechanical properties of the CSD are in different fiber orientations...
  14. pmc Effect of adjustable passive constraint on the failing left ventricle: a finite-element model study
    Choon Sik Jhun
    Department of Surgery, University of California, San Francisco, California, USA
    Ann Thorac Surg 89:132-7. 2010
    ..This study determined the relationship between constraint, diastolic wall stress, chamber stiffness, and pump function. We tested the hypothesis that passive constraint at 3 mm Hg reduces wall stress with minimal change in pump function...
  15. pmc Finite element modeling of mitral leaflet tissue using a layered shell approximation
    Jonathan F Wenk
    Department of Mechanical Engineering, University of Kentucky, Lexington, KY 40506 0503, USA
    Med Biol Eng Comput 50:1071-9. 2012
    ..This confirms that the layered composite approximation presented in the current study is able to capture the exponential stiffening seen in both the circumferential and radial directions of mitral leaflets...