Research Topics
| Jonathan F WenkSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Regional left ventricular myocardial contractility and stress in a finite element model of posterobasal myocardial infarctionJonathan F Wenk
Department of Surgery, University of California San Francisco, CA 94121, USA
J Biomech Eng 133:044501. 2011..The myofiber stress in the BZ was found to be elevated, relative to the remote region. This could cause further damage to the contracting myocytes, leading to heart failure...
Numerical modeling of stress in stenotic arteries with microcalcifications: a micromechanical approximationJonathan F Wenk
Department of Mechanical Engineering, University of California Berkeley, CA 94720 1740, USA
J Biomech Eng 132:091011. 2010..This is a possible explanation of why 40% of plaque ruptures occur away from the shoulder region of the cap...
Viscoelastic and biomechanical properties of osteochondral tissue constructs generated from graded polycaprolactone and beta-tricalcium phosphate compositesCevat Erisken
Stevens Institute of Technology, Hoboken, NJ 07030, USA
J Biomech Eng 132:091013. 2010..These experimental findings suggest that viscoelastic material functions of the tissue constructs can provide valuable inputs for the stages of in vitro tissue development...
Numerical modeling of stress in stenotic arteries with microcalcifications: a parameter sensitivity studyJonathan F Wenk
Department of Bioengineering, University of California San Francisco, CA 94121, USA
J Biomech Eng 133:014503. 2011..Biomech. Eng., 132, p. 091011), which indicates that the maximum circumferential stress always shifts to the region of microcalcification...
Dor procedure for dyskinetic anteroapical myocardial infarction fails to improve contractility in the border zoneKay Sun
Department of Surgery, University of California, San Francisco, Calif, USA
J Thorac Cardiovasc Surg 140:233-9, 239.e1-4. 2010..Endoventricular patch plasty (Dor) is used to reduce left ventricular volume after myocardial infarction and subsequent left ventricular remodeling...
The effect of mitral annuloplasty shape in ischemic mitral regurgitation: a finite element simulationVincent M Wong
Department of Surgery, University of California, San Francisco, San Francisco, CA 94121, USA
Ann Thorac Surg 93:776-82. 2012..Undersized mitral annuloplasty (MA) is the preferred surgical treatment for chronic ischemic mitral regurgitation. However, the preferred shape of undersized MA is unclear...
First evidence of depressed contractility in the border zone of a human myocardial infarctionJonathan F Wenk
Department of Mechanical Engineering, University of Kentucky, Lexington, Kentucky, USA
Ann Thorac Surg 93:1188-93. 2012..We sought, for the first time, to document the presence of impaired contractility of the myofibers in the human BZ myocardium...
First finite element model of the left ventricle with mitral valve: insights into ischemic mitral regurgitationJonathan F Wenk
Department of Surgery, University of California, San Francisco, California, USA
Ann Thorac Surg 89:1546-53. 2010..Left ventricular remodeling after posterobasal myocardial infarction can lead to ischemic mitral regurgitation. This occurs as a consequence of leaflet tethering due to posterior papillary muscle displacement...
A novel method for quantifying the in-vivo mechanical effect of material injected into a myocardial infarctionJonathan F Wenk
Department of Surgery, University of California, San Francisco, Department of Veterans Affairs Medical Center, San Francisco, California 94121, USA
Ann Thorac Surg 92:935-41. 2011..We sought to quantify the effects of injecting a calcium hydroxyapatite-based tissue filler on the passive material response of infarcted left ventricles...
Material properties of CorCap passive cardiac support deviceSam Chitsaz
Department of Surgery, University of California at San Francisco and San Francisco Veterans Affairs Medical Center, San Francisco, California, USA
Ann Thorac Surg 95:148-54. 2013..However, as an open mesh surrounding the heart, it is unknown what the mechanical properties of the CSD are in different fiber orientations...
Effect of adjustable passive constraint on the failing left ventricle: a finite-element model studyChoon Sik Jhun
Department of Surgery, University of California, San Francisco, California, USA
Ann Thorac Surg 89:132-7. 2010..This study determined the relationship between constraint, diastolic wall stress, chamber stiffness, and pump function. We tested the hypothesis that passive constraint at 3 mm Hg reduces wall stress with minimal change in pump function...
Finite element modeling of mitral leaflet tissue using a layered shell approximationJonathan F Wenk
Department of Mechanical Engineering, University of Kentucky, Lexington, KY 40506 0503, USA
Med Biol Eng Comput 50:1071-9. 2012..This confirms that the layered composite approximation presented in the current study is able to capture the exponential stiffening seen in both the circumferential and radial directions of mitral leaflets...
