David Welsh

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Suprachiasmatic nucleus: cell autonomy and network properties
    David K Welsh
    Department of Psychiatry, University of California San Diego, La Jolla, CA 92093, USA
    Annu Rev Physiol 72:551-77. 2010
  2. ncbi Intercellular coupling confers robustness against mutations in the SCN circadian clock network
    Andrew C Liu
    Department of Biochemistry, The Scripps Research Institute, La Jolla, CA 92037, USA
    Cell 129:605-16. 2007
  3. ncbi Gate cells see the light
    David K Welsh
    Department of Biochemistry, Scripps Research Institute, La Jolla, CA 92037, USA
    J Biol Rhythms 22:26-8. 2007
  4. ncbi Reciprocity between phase shifts and amplitude changes in the mammalian circadian clock
    Sandhya R Pulivarthy
    Regulatory Biology Laboratory and Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 104:20356-61. 2007
  5. ncbi Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression
    David K Welsh
    Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Curr Biol 14:2289-95. 2004
  6. ncbi Bioluminescence imaging in living organisms
    David K Welsh
    Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Curr Opin Biotechnol 16:73-8. 2005
  7. ncbi Redundant function of REV-ERBalpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms
    Andrew C Liu
    Section of Cell and Developmental Biology, Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America
    PLoS Genet 4:e1000023. 2008

Research Grants

  1. Circadian Clock Cells: Autonomy Persistence and Calcium Dependence
    David K Welsh; Fiscal Year: 2010

Collaborators

  • S A Kay
  • Joseph S Takahashi
  • Satchidananda Panda
  • Andrew C Liu
  • Eric E Zhang
  • Hien G Tran
  • Aaron A Priest
  • Sandhya R Pulivarthy
  • Inder M Verma
  • Ethan D Buhr
  • Kirsten Meeker
  • Nobushige Tanaka
  • Francis J Doyle
  • Oded Singer
  • Caroline H Ko
  • Luciano De Haro

Detail Information

Publications7

  1. ncbi Suprachiasmatic nucleus: cell autonomy and network properties
    David K Welsh
    Department of Psychiatry, University of California San Diego, La Jolla, CA 92093, USA
    Annu Rev Physiol 72:551-77. 2010
    ..Thus, even though individual SCN neurons can be cell-autonomous circadian oscillators, neuronal network properties are integral to normal function of the SCN...
  2. ncbi Intercellular coupling confers robustness against mutations in the SCN circadian clock network
    Andrew C Liu
    Department of Biochemistry, The Scripps Research Institute, La Jolla, CA 92037, USA
    Cell 129:605-16. 2007
    ....
  3. ncbi Gate cells see the light
    David K Welsh
    Department of Biochemistry, Scripps Research Institute, La Jolla, CA 92037, USA
    J Biol Rhythms 22:26-8. 2007
  4. ncbi Reciprocity between phase shifts and amplitude changes in the mammalian circadian clock
    Sandhya R Pulivarthy
    Regulatory Biology Laboratory and Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 104:20356-61. 2007
    ..Real-time monitoring of PER2 oscillations in single cells reveals that changes in both synchrony and amplitude of individual oscillators underlie these phenomena...
  5. ncbi Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression
    David K Welsh
    Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Curr Biol 14:2289-95. 2004
    ....
  6. ncbi Bioluminescence imaging in living organisms
    David K Welsh
    Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Curr Opin Biotechnol 16:73-8. 2005
    ..Recent applications have included longitudinal monitoring of tumor progression in vivo, and monitoring circadian rhythms with single-cell resolution...
  7. ncbi Redundant function of REV-ERBalpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms
    Andrew C Liu
    Section of Cell and Developmental Biology, Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America
    PLoS Genet 4:e1000023. 2008
    ..Since REV-ERB function and Bmal1 mRNA/protein cycling are not necessary for basic clock function, we propose that the major role of the ROR/REV/Bmal1 loop and its constituents is to control rhythmic transcription of clock output genes...

Research Grants2

  1. Circadian Clock Cells: Autonomy Persistence and Calcium Dependence
    David K Welsh; Fiscal Year: 2010
    ....